• 한국의상디자인학회지
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• 제18권3호
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• pp.71-83
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• 2016

This study attempted to analyze trends of structural changes in the front middle part of men's underwear and get basic data for the development of men's underwear patterns. In terms of a research method, the structure and pattern of the front middle part of men's underwear were analyzed by referring to the design and description of the drawing, focusing on men's underwear which targeted to isolate penis from scrotum among the 'men's underwear' or 'functional men's underwear'-related patents. According to the study, three topics were obtained as follows: a support attached to the inside of the front middle part; inner cloth attached to the inside of the front middle part; change in the structure of the front middle panel. The aspects by the specific topic targeted to isolate penis from scrotum and prevent the scrotum from adhered to a thigh are as follows: 1) When a support is attached to the inside of the front middle part, the following three methods are proposed: Penis isolated from scrotum by a rest which is designed using the band; penis and scrotum rested in the band and in a pocket respectively; protruded rest inside the front middle part of the underwear. 2) When an inner cloth is attached to the inside of the front middle part, the following methods are designed: A pocket-type inner cloth is attached; isolation of penis hole from the scrotum pocket using a rectangular separator; U-shaped pocket designed to rest penis and scrotum is attached. 3) Regarding change in the structure of the front middle panel, the integration of penis and scrotum resting parts can be divided into two cases: Securing a space using wrinkles; keeping it voluminous using the vertical line. In this all-in-one penis and scrotum-holding type, in addition, different front panel patterns were applied.

• Archives of Plastic Surgery
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• 제38권6호
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• pp.899-902
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• 2011

Purpose: Lymphedema of the scrotum and penis is a functionally and emotionally incapacitating problem for patients. Patients suffer pain from swelling, chronic irritation, repeated infections, drainage, and sexual dysfunction. Although there are various methods for the treatment of scrotal and penial lymphedema, achieving a satisfactory reconstruction in severe cases still remains a challenge due to the lack of locally available tissue. Methods: A 33-year-old man sustained severe lymphedema of the scrotum and penis. He reported a history of swelling since 25 years, which had been intensified during the past few months. There was no history of irritation, surgery, trauma, infection or travel to endemic countries. The authors reconstructed the scrotum and penis using 4 scrotal flaps made by incising the enlarged scrotum crucially. Results: The postoperative course was uneventful. Histopathologic examination showed nonspecific chronic inflammation. The patient was followed up for 18 months and a good reconstructive result was obtained with no recurrence. Conclusion: The authors' method is safe and easy to perform. This method may be a convenient and reliable alternative for the treatment of severe lymphedema of the scrotum and penis.

• Archives of Plastic Surgery
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• 제35권5호
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• pp.619-621
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• 2008

Purpose: By virtue of good nourishment, obese boys are increasing in Korea, which may result in prevalence of cryptopenis. As milieu of economy, culture, and society changes, increased attention to the external genitalia in children should encourage surgeon to do assertive treatment for cryptopenis. But various operative methods have been devised yet to need sophistication and revision. The author performed suprapubic lipectomy and operation according to the modification of the Johnston's principle. Methods: The patient was 5 years old, 32 kg, and 122 cm. He had no pain or tenderness. The operation was done under general anesthesia. It was done with excision of suprapubic fat, cutting of retracted dartos fascia instead of removing the fascia around penile base, and anchoring of dermis and the cutting margin of the fascia to the underlying fascia such as Buck's fascia, tunica albuginea and rectus fascia at penile base. And then circumcision was performed. Results: Postoperative complication was not observed. The clinical result of the operation was satisfactory to both surgeon and parents of the patient. Conclusion: Suprapubic lipectomy and anchoring of dermis and retracted cutting dartos fascia margin to the underlying fascia in all directions at the penile base through a single suprapubic incision provide this patient with complacency.

• 정신신체의학
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• 제7권1호
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• pp.10-25
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• 1999

2세이상의 어린이는 성적 흥분을 느낄 수 있기에 만지거나 자위행위 등의 성적인 즐거움을 찾기 시작 한다. 60년대 후반부터 70년대 초반사이 산부인과 의사 Masters와 사회사업가 Johnson은 인간의 성반응 단계를 흥분기, 고원기, 오르가슴기, 반응소실기의 4단계로 나눠 설명하였고, 여성에게는 무반응기가 없어 여러번의 오르가슴이 가능함을 밝혔다. 그들의 성치료원칙은 행동치료에 입각하여 감각초점법과 부부치료, 성교육등으로 구성되어있다. Masters와 Johnson이후 정신과 의사이자 정신분석가인 Kaplan이 1970년대 초반에 정신분석적 정신치료와 행동치료를 결합한 '새로운 성치료'를 제안했다. 그리고, 성기능 장애를 3가지 카테고리로 재분류했다. 1980년대 이후는 남성의 발기부전의 치료를 중심으로 의학적 치료방법론이 대세를 이루고 있는데, 음경 보속물, 국소주사치료, 경구약제등이 발달하였다. 최근 Sildenafil(Viagra)이 등장해 남성 발기부전 치료의 최선의 선택으로 받아들여지고 있다.

• 한국한의학연구원논문집
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• 제6권1호
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• pp.69-80
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• 2000

Objectives : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea(合穴) points in branches of the twelves meridians will be representative of measurements of the twelve meridians, to measure the electric potentials in twenty healthy volunteers when they were sleeping or waking respectively, to do significance test for electric potential of meridian system between hand and foot meridian, yin and yang meridian, exterior and interior of the body, and among the five elements. Methods : When twenty healthy volunteers were sleeping, their electric potentials of well and sea points in branches of the twelve meridians were simultaneously measured by physiograph. After a minute we measured them again, totally 5 times. And then when they were waking, their electric potentials were measured 5 times by the above method. Results : Measurements were analyzed by statistical t-test, we obtained that the left side electric potential of hand or yin meridian was significantly different from that of foot or yang meridian both sleeping and waking. The right side of electric potential was the same result as the left side's. Most of the t-test was significant between exterior and interior of the body, and among the five elements. That meaned that it was partly possible to apply the ancient theory of meridians to the study of electric potential at well and sea points in branches of the twelves meridians.

• 약학회지
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• 제41권3호
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• pp.370-380
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• 1997

The role of nitric oxide (NO) on the non-adrenergic non-cholinergic (NANC) relaxations induced by the short and prolonged electrical field stimulation (EFS) has been studied in the rabbit corpus cavernosum. In the presence of atropine and guanethidine the prolonged EFS (2-16 Hz) of corpus cavernosal strips precontracted with phenylephrine produced frequency-dependent relaxations, which were abolished by tetrodotoxin as shown in the relaxations induced gy the short EFS, indicating that their orgin is NANC nerve stimulation. $N^G$-nitro-L-arginine (L-NNA), inhibitor of nitirc oxide synthase, caused a concentration-dependent inhibition to the NANC relaxation, and at 100 M L-NNA the relaxation were virtually abolished. The inhibitory effect of L-NNA was reversed by L-arginine. Hemoglobin abolished the relaxations to NO and also caused a concentration-dependent inhibition of the NANC relaxation. The hemoglobin-resistant relaxation induced by EFS was eliminated by L-NNA. Methylene blue significantly reduced the NANC relaxation in a conentration-dependent manner. The NANC relaxation was not affected by a VIP-inactivating pepridase, alpha0chymotrypsin, whereas VIP-induced relaxation was completely abolished. NO- and VIP-induced relaxation were not affected by L-NNA. These results indicate that the NANC relaxation induced by prolonged EFS of the rabbit corpus cavernosum is mediated by NO-guanosine 3',5'-cyclic monophosphate pathway as shown in the relaxation induced by the short EFS, and that VIP release is not essential for the NANC relaxation of the rabbit corpus cavernosum and VIP is not involved the generation fo NO.

• 대한본초학회지
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• 제30권4호
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• pp.71-79
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• 2015

Objectives : These present study was designed to investigate the relaxation effects of Alpiniae Oxyphyllae Fructus(AOF) on isolated corpus cavernosum smooth muscle.Methods : Rabbit corpus cavernous tissues were prepared in strip. Then relaxation responses of AOF at 0.01-3 ㎎/㎖ in contracted strips induced by phenylephrine(PE) were measured. To evaluate mechanisms, indomethacin(IM) tetraethylammonium chloride(TEA), Nω-nitro-L-arginine(_L-NNA), methylene blue(MB) were treated before AOF extract(0.1-3 ㎎/㎖) infused into precontracted strips induced by PE. And 1 mM Ca²⁺was infused into precontracted strips after pretreatment of AOF extract(3 ㎎/㎖) in Ca²⁺-free krebs-ringer solution. NO concentration was measured by Griess reagent system. Ratio of smooth muscles to collagen fibers and eNOS positive reaction were measured by histocheminal and immunohistochemical process.Results : The cavernous strips were significantly relaxed by AOF extract 0.1, 0.3, 1, 3 ㎎/㎖ and the pretreatment with IM 10 μM,_L-NNA 100 μM, MB 10 μM inhibited relaxation of AOF compared to non-pretreatment, but the pretreatment with TEA 100 μM didn't affect relaxation of AOF. In a Ca²⁺-free solution, pretreatment with AOF reduced increase on contraction of strips by Ca²⁺supply than non-pretreatment. On HUVEC, NO concentration was increased. On corpus cavernosum of penis in Spontaneous Hypertensive Rat, ratio of smooth muscles to collagen fibers and eNOS positive reaction in AOF group were increased compared to PE groupConclusions : Taken this results, we can suggest that AOF extract exerts a relaxation effects on rabbit corpus cavernosum smooth muscle in part by suppressing influx of extracellular Ca²⁺throughout prostacyclin, the NO-cGMP system.

• 한국의학물리학회지:의학물리
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• 제19권3호
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• pp.172-177
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• 2008

정량적인 방사선치료 선량을 예측하기위한 일환으로 한국표준남성에 기초하여 수학적 모의피폭체를 제작하였다. 이후 전립선을 선원장기로 하여 전립선암 근접치료 시 발생할 것으로 예상되는 전립선 및 주변장기의 흡수선량을 산정하였다. 모의모사를 위하여 방사성핵종은 전립선 근접치료에 유용하게 사용되는 $^{25}I$ 및 $^{103}Pd$선정하였고, 초기 방사능을 1 Ci를 투여하는 것으로 가정하였다. 그 결과 선원장기인 전립선이 $^{125}I$ 및 $^{103}Pd$ 경우 각각 101 Gy/Ci와 7.24 Gy/Ci를 나타냈으며, 전립선을 제외하고 흡수선량이 높은 장기는 비교적 전립선과 인접되어 있는 장기 즉 음경과 음낭, S자결장, 정소, 방광순으로 나타났다.

• 대한의생명과학회지
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• 제2권2호
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• pp.283-288
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• 1996

최근 한국에 있어서 광절열두조충 감염예가 가끔 보고되고 있다. 저자등은 1994년 10월 강원도 춘천시 거주 남녀 부부가 함께 담수산 송어회를 먹고 감염된 2예에 대하여 보고하는 바이다. 구충은 하제로서 Magnesium sulfate 15gm, 구충제 Praziquantel 15mg/kg를 투여하였다. 제1예는 인ㅇㅇ, 43세 남자, 69kg의 건강체였으며, 구충하여 얻은 충체의 길이 6.65m, 폭 8-13mm였다. 제2예는 최ㅇㅇ, 39세 여자, 56kg으로 소화불량, 복부 불쾌감을 호소하였고, 구충하여 얻은 충체는 5.50m, 폭 8-13mm이었다. 2예 모두에서 두부는 검출되지 않았다. 구충하여 얻은 충체의 외관상 형태, 자궁의 선회, 자궁분지(uterine loops)의 수, 생식공의 위치와 절단표본상 음경낭과 저정낭의 형태, 질의 위치, 자궁구의 위치등과 충란을 광학현미경으로 관찰 한 형태, 크기 및 SEM으로 관찰한 표피의 작은 점각(pits)의 유무, 분포 등 형태학적인 특징등으로 Diphyllobothrium latum으로 동정하였다. 이번의 인체 감염은 담수산 송어회가 원인이 된 것으로 믿어지는 예이다.

• 동의생리병리학회지
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• 제28권2호
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• pp.169-177
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• 2014

This study aimed to investigate the relaxation effects and its underlying mechanisms of Epimedium koreanum Nakai(EK) in phenylephrine(PE) treated isolated rabbit corpus cavernosum smooth muscle. The dose-dependent relaxation responses of phenylephrine(PE, $1{\times}10^{-6}M$)-precontracted strips to EK at $0.01-3.0mg/m{\ell}$ were measured and also observed after endothelial denudation using organ bath. To analyze the underlying mechanisms of EK-induced relaxation, $N{\omega}$-nitro-L-arginine(L-NNA), methylene blue(MB), tetraethylammonium chloride(TEA), indomethacin(IM) were pretreated before EK extract infused into precontracted strips induced by PE. To investigate cytotoxic activity and nitric oxide(NO) concentration of EK extract on EA.hy926 cells, mitochondrial dehydrogenase activity(MTT) assay and nitric oxide detection kit were used. The cavernous strips were significantly relaxed by EK extract at $0.3mg/m{\ell}$, $1.0mg/m{\ell}$, $3.0mg/m{\ell}$ and the relaxation responses of PE-precontracted strips denuded endothelium also inhibited in comparison with intact endothelium. The pretreatment of L-NNA, MB, TEA reduced EK extract-induced endothelium-dependent relaxation, but the pretreatment of IM didn't affect EK extract-induced endothelium-dependent relaxation. When EK extract was applicated on EA.hy926 cells, the NO concentration was increased. Our findings have shown that EK extract exerts a relaxing effect on corpus cavernosum in part by suppressing influx of extracellular $Ca^{2+}$ through activating the NO-cGMP system.