• Analytical Science and Technology
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• v.20 no.4
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• pp.347-354
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• 2007

A simple and rapid high-performance liquid chromatography assay for the determination of residual novobiocin levels in bovine, porcine, chicken, flatfish and japanese eel muscle has been developed and validated. The separation condition for HPLC/UV was optimized with phenyl hexyl ($4.6{\times}150mm$, $5{\mu}m$) column with 10 mM monobasic sodium phosphate buffer (pH 2.5)/acetonitrile (50/50, v/v) as the mobile phase at a flow rate of 1.0 mL/min and detection wavelength was set at 254 nm. Residues were extracted from tissue by blending with methanol and lipid materials were removed with n-hexane. Then, the methanol extract was evaporated to dryness under a nitrogen stream, reconstituted in the mobile phase. Aliquot of the organic extract was decanted and filtered through $0.45{\mu}m$ syringe filter. The $20{\mu}L$ of the resulting solution was injected into the HPLC system. The calibration ranges were $0.5{\sim}5{\mu}g/g$ and calibration curves were linear with coefficients of correlation better than 0.95. The limits of quantification were $0.5{\mu}g/g$ for all muscles. The recoveries of bovine, porcine, chicken, flatfish and japaneseel muscles were 99.8%, 102.4%, 91.0%, 104.0% and 93.0%, respectively. The procedures were validated according to the CODEX guideline, determining specificity, linearity, accuracy, precision, quantitation limit and recovery.

• Analytical Science and Technology
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• v.20 no.4
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• pp.323-330
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• 2007

A simple and rapid HPLC method with fluorescence detection(FLD) for quantitation of penciclovir in human plasma using a monolithic column was developed and validated. Penciclovir and ganciclovir(internal standard, I.S.) were separated on a Chromolith column RP-18e ($4.6{\times}100mm$) with a mobile phase consisting of a mixture of (A) methanol/50 mM sodium phosphate buffer containing 200 mg/L sodium dodecyl sulfate (3/97, pH 2.5) and (B) methanol/50 mM sodium phosphate buffer containing 200 mg/L sodium dodecyl sulfate (50/50, pH 2.5) at a flow gradient of $1.6{\sim}4.0mL/min$. The retention times of penciclovir and internal standard were less than 4.0 min. Calibration curve was linear ($R^2=0.9994$) over a concentration range of $0.1{\sim}5{\mu}g/mL$. Intra-day precision, accuracy and inter-day precision were 1.36~8.55 %, 92.8~100.0 % and 0.93~5.62 %, respectively with a limit of quantitation at $0.1{\mu}g/mL$. The present HPLC-FLD method is sensitive, precise and accurate. The method described herein has been successfully used for the bioequivalence study of a famciclovir formulation product after oral administration to healthy Korean volunteers.

• 한국노년학
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• v.29 no.2
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• pp.425-440
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• 2009

The purpose of this study was to understand the ability of the elderly to activity of daily living, assess their quality of sleep and level of depression at home and analyze how such relate health related quality of life. The subject was 223 senior over 65 years old who lived in B Metropolitan City. Descriptive statistics, independent t-test, one-way ANOVA, Pearson correlation and stepwise multiple regression were performed using SPSS WIN 14.0. The major findings of this study are as follow: 1) 34.1% of the respondents experienced a degree of sleep disorder and 57.8% were vulnerable to depression. 2) Activity of daily living, quality of sleep and depression were related to health related quality of life to a statistically significant degree. quality of sleep, activity of daily living positively related to health related quality of life. level of depression related to health related quality of life. Stepwise multiple regression analysis revealed the most powerful predictor of health related quality of life was depression. While age, level of education and quality of sleep were also found as significant predictor variables. Based on these results, it is necessary to perform more studies on health related quality of life and related factors according to that in various settings. Especially, to develop a program intended to improve the health related quality of life of the elderly at home, we need to consider not only physical factors but also psychological factors.

• Korean Journal of Social Welfare Studies
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• v.42 no.2
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• pp.123-153
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• 2011

This study tries to categorize innovation types for social welfare organizations and investigate the level of innovation in each type in practical field. Firstly, this study scrutinizes the concept and classification's criterias of innovation. Secondly, this study reviews not only classification of innovation in profit organization but also several researches of innovation in service industry and public sectors, and finally, this study makes a suggestion of innovations' classification that is applicable for social welfare organizations. Based on this suggestion, fifteen questions are designed to ask the innovative activities in the organizations. And total 496 respondents from 116 organizations answered these questionnaire. The outcomes of this survey were substantiated by second data through converted procedures to mean value of organizations. Consquently, service innovation, administrative innovation and human resource innovation, proposed based on theoretical review, were subdivided into six categories such as service innovation, structural innovation, internal and efficiency innovation, marketing and communication innovation, external and employment innovation and evalution and mission innovation. The mean value of service(mean=14.7) and marketing innovation(mean=13.3) are higher than other type of innovations, which shows the aspect of innovative activities in social welfare organizations. Based on this result, we can get the directions of following study in investigating innovation of social welfare organization.

• Korean Journal of Culture and Social Issue
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• v.22 no.1
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• pp.119-135
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• 2016

We tried to develop the school violence prevention program which focuses on the bystanders. In the context of school violence, most students are bystanders. They can either reinforce the violence or stop the violence. We hypothesized that the students who know their own temperament dimensions such as novelty seeking, harm avoidance, and reward dependence (Cloninger, 1994) will show more tendencies to defend victims from school violence when they learned the methods to prevent school violence in accordance to their temperament dimensions. 351 Korean middle school students participated the 4 sessions of school violence prevention program. The students completed the questionnaires to identify their own behavior in school violence situations. In the experimental group(temperament group), students learned the methods to help the victims that suits with their own temperaments. Whereas, the comparison group just attend the class regardless of their temperaments. Both groups showed significant increase in the trend of defending the victims. However, the temperament group showed more tendency to protect/defend the victims than the comparison group when they faced with school violence. These results show that students can learn the methods of defending victims from school violence more easily by knowing their own temperament dimensions, and can be the prepared and the effective defenders.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2020.08a
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• pp.81-81
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• 2020

본 연구는 새싹인삼(Panax ginseng sprout) 재배용으로 이용하기 위한 묘삼(종삼)의 장기 저온저장 시 사용되는 필름의 종류가 묘삼의 출아율이나 생육에 영향을 미치는 지 조사하기 위해 수행되었다. 포장에 사용된 필름은 다공성물질인 제올라이트와 페그마타이트가 5% 함유된 50㎛ low density polyethylene(기능성 LDPE) 필름과 nylon/polyethylene 80 ㎛(Ny/PE) 필름에 묘삼을 100g씩 포장한 후 골판지 상자에 담아 -2℃의 저장고에서 10개월 동안 저장하면서 8개월째부터 2개월마다 시료를 꺼내어 5℃에서 5일 동안 온도 순화를 시킨 후 1차 조사에서는 육안조사로 실험실에서 건전한 묘삼과 부패 묘삼을 조사하였고, 건전한 묘삼만 새싹인삼 수경재배 농가에 재식한 후 2차 조사로 묘삼의 출아율과 출아된 묘삼이 새싹인삼으로 건전하게 생육한 비율을 조사하였다. 조사결과 Ny/PE 필름에 8개월 저장된 묘삼의 경우 1차 육안검사 시 뇌두부위가 검게 변하여 묘삼이 대부분 고사된 것으로 조사되었다. 필름 개봉 전 필름 내부의 O₂ 및 CO₂ 가스농도를 측정한 결과 O₂ 농도는 1.91%, CO₂ 농도는 38.9%로 측정되었고, 필름 개봉 시 알코올 냄새의 이취가 나는 것으로 보아 Ny/PE 필름으로 포장 된 묘삼이 -2℃의 저온저장기간 동안에도 호흡을 하면서 필름 내 산소를 완전히 소모하고 혐기적인 환경으로 변화시켜 대사활동이 불가능하였기 때문에 뇌두의 싹이 고사된 것으로 조사되었다. 반면 기능성 필름으로 포장한 묘삼은 저장 8개월에 정식 후 74.3%의 출아율을 보였고, 건전한 새싹인삼의 비율은 67.2%로 조사되었다. 정식 전·후 묘삼의 개체수 대비 건전 출아율의 비율은 56.7%를 나타내어 Ny/PE 필름으로 포장한 묘삼의 결과와 큰 차이를 보였다. 기능성필름의 개봉 전 필름 내부의 O₂ 및 CO₂ 가스농도를 측정한 결과 O₂ 농도는 12.9%, CO₂ 농도는 4.6%로 측정되어 묘삼의 저온저장 시 필름을 적용할 경우 공기의 유동이 원활이 이루어져 내부 O₂ 농도를 일정 수준 이상 유지해주는 필름을 사용하는 것이 묘삼의 출아와 생육에 좋은 것으로 조사되었다.

• Textile Coloration and Finishing
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• v.35 no.4
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• pp.196-205
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• 2023

Water-dispersed pigment is on-going study for without air pollution in the textile and print industry. Primer treatment is essential for the substrate to improve the printing quality of eco-friendly water-dispersed pigment ink. Otherwise in the case of untreated primer, the water-dispersed pigment ink will dry onto the surface and cause defective images. This study was conducted on film substrate coating (primer) to fix eco-friendly water-dispersed pigment ink on film substrate. The drying, bleeding, and color strength of the pigment ink were examined depending on the composition and mixing ratio of the coating solution. The mixing ratio of silica gel in the coating film is increased to 0, 0.5, 1, 2 and 3 and results that DK-1-3 of silica gel ratio of 1 showed the lowest bleeding such as 52%, the letter thickness of 0.76mm and DK-1-5 of SG ratio of 3 showed the highest bleeding such as 304%, the letter thickness of 2.02mm. The mixing ratio of SPA in the coating film is increased to 2.5, 5, 7.5, SPA ratio of 7.5 has a bleeding ratio of 9% and letter thickness of 0.544mm. It showed the closest value to 0.5mm. According to the result, the optimal mixing ratio of binder, polymer coagulant, silica gel is 100:7.5:1.

• Journal of Marine Life Science
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• v.8 no.2
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• pp.178-185
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• 2023

This study was described the microscopic anatomy of male reproductive organs and spermatophore necessary for understanding the reproductive ecology of the long arm octopus Octopus minor. The long arm octopus was a species that has sexual dimorphism that can distinguish between sex based on the presence of hectocotylus. Male reproductive organs consisted of testis, primary spermatic duct, spermatic gland, secondary spermatic duct, spermatophoric gland and spermatophoric sac. Histologically, the testis was testicular tubule type and male germ cells showed a layered arrangement. The primary spermatic duct was a tube connecting the testis and spermatic gland, and consisted with epithelial layer and connective tissue. The spermatic gland was located between the primary and secondary spermatic duct, and the epithelial layer was composed of epithelial cells and mucous cells. Mucous cells reacted blue in the AB-PAS (pH 2.5) reaction and purple in the AF-AB (pH 2.5) reaction. The secondary spermatic duct was a short tube connecting spermatic gland and spermatophoric gland, and folds were developed in lumen. The spermatophoric gland consisted of numerous tubular glands and secretory cells had eosinophilic granules. The spermatophoric sac was shape of pouch, folds were developed in lumen, and vacuolar secretory cells were present in the epithelial layer. The spermatophore was 83.5 mm long and consisted of cap thread in anterior portion, ejaculatory apparatus and cement body in medial portion, sperm mass in posterior portion.

• Korean Journal of Remote Sensing
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• v.39 no.6_1
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• pp.1477-1482
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• 2023

This study examines marine heat wave (MHW) in the Northeast Asia region from 2012 to 2021, utilizing geostationary satellite Communication, Ocean, and Meteorological Satellite (COMS)/Meteorological Imager sensor (MI) and GEO-KOMPSAT-2A (GK-2A)/Advanced Meteorological Imager sensor (AMI) Sea Surface Temperature (SST) data. Our analysis has identified an increasing trend in the frequency and intensity of MHW events, especially post-2018, with the year 2020 marked by significantly prolonged and intense events. The statistical validation using Optimal Interpolation (OI) SST data and satellite SST data through T-test assessment confirmed a significant rise in sea surface temperatures, suggesting that these changes are a direct consequence of climate change, rather than random variations. The findings revealed in this study serve the necessity for ongoing monitoring and more granular analysis to inform long-term responses to climate change. As the region is characterized by complex topography and diverse climatic conditions, the insights provided by this research are critical for understanding the localized impacts of global climate dynamics.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.595-604
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• 2023

This study attempted to provide basic data for developing strategies to improve the psychosocial well-being on nursing university students by identifying the mediating effect of resilience on the relationship between clinic practice stress and psychosocial well-being of nursing university students. The subjects of the study were 175 nursing students in their 3^rd and 4^th year who had clinic practice experience at two universities in J province and G city. The SPSS/23.0 program was used to analyze the data with descriptive statistics; an independent t-test, analysis of variance ANOVA, Pearson's correlation coefficient, and mediating effect analysis were performed using Process Macro 4.0. The psychosocial well-being of nursing university students showed a positive correlation with clinical practice stress (r=.472, p<.001), and a negative correlation with resilience (r=-.860, p<.001). Resilience showed a mediating effect on the relationship between clinical practice stress and psychosocial well-being. Based on the results of this study, it is necessary to development and apply systematic programs to reduce clinical practice stress and increase resilience for improving the psychosocial well-being of nursing university students.