• Korean Journal of Clinical Laboratory Science
• /
• v.52 no.4
• /
• pp.381-388
• /
• 2020

The quality control of pathological specimens is important for accurate molecular pathology testing. This study evaluated that specimen factors affecting the DNA quality during tissue processing and sample types for BRAF, EGFR, and KRAS mutations tests. One thousand seven hundred and seventy-two molecular pathology tests were investigated for the factors influencing the DNA quality, such as sample type, formalin fixation time, and reexamination status. Cytology samples stored in a saline solution had better DNA quality than commercial cytology preservation. Tissue samples fixed in formalin within 24 hours had better DNA quality than the samples fixed over 24 hours. Between the types of samples, fresh tissue samples and tissue samples with a high tumor cell density had relatively better DNA quality than the formalin-fixed paraffin-embedded (FFPE) tissues and cytology specimens. Of real-time PCR, the non-PNA Ct value increased proportionally with samples held for longer than 24 hours in formalin, and that the formalin-fixed time affects the sample DNA quality. In conclusion, the appropriate tumor cellularity and 10% neutral formalin fixation time are the most important factors for maintaining the DNA quality. These factors should be managed properly for an accurate pathological molecular test to ensure optimal DNA quality.

• Journal of Korean Society of Archives and Records Management
• /
• v.21 no.1
• /
• pp.189-209
• /
• 2021

This study aims to examine the current status of and problems in records management by the person in charge of university records management and derive improvement measures to manage university processing and records management systematically. The study's results are as follows: first, administrative problems with processing and service, and second, issues arising from records management procedures, such as the production and registration of processing departments, notification of production status, transfer, cleanup and physical storage, and assessment and disposal, as well as the lack of knowledge and records management. In response, it was suggested that training is needed to improve processing and records management manuals, secure physical storage, strengthen administrative support for the division in charge, ensure the legitimate status of the person in charge of processing and records management in the division in charge, and enhance the recognition of records management by the person in charge and manager.

• Journal of the Korean Applied Science and Technology
• /
• v.37 no.6
• /
• pp.1687-1697
• /
• 2020

This study is a comparative descriptive research that identifies the degree and difference of the brain education meditation program from participation stress(physical stress, psychological stress), depression, resilience(self-control ability, interpersonal relationship ability, and positive) for middle-aged women. The subjects were 26 middle-aged women who participated in the brain education meditation program at the D metropolitan city D center for more than a year, 29 middle-aged women did not participate in the brain education meditation program and a total of 55 middle-aged women collected for three weeks from November 4 to 22, 2019. Data analysis fesult that the participating groups in brain education meditation programs differ statistically significantly in physical stress(t=2.549, p=.014), psychological stress(t=2.352, p=.022), self-control ability(t=-2.219, p=.031) and positive(t=-2.387, p=.021), which are higher factors in resilience than non-participating groups. In other words, brain education meditation program participants scored lower physical and psychological stress scores than nonparticipating groups, with higher self-control ability and positive scores. Therefore, it is thought that brain education meditation programs can be used as nursing intervention to reduce stress and improve self-control ability and positive in middle-aged women.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.3
• /
• pp.138-147
• /
• 2021

The purpose of this study was to develop a measuring tool for the health promotion behavior of Korean nurses. This would address the lack of a proven tool that reflects the nature of the nurses' nursing environment. This study was conducted on 530 nurses from January to December 2019. A literature review and focus group interview were conducted, data analysis was carried out to measure validity and reliability, and the conceptual framework was constructed by applying the IMB model. Five factors namely self-concept (2 questions), hospital life management (4 questions), knowledge and information regarding health (5 questions), physical and mental stress management (3 questions), and work adaptation (2 questions) were framed into 16 questions. The model fit was 346.23 (��<.001), Parsimonious Normed Fit Index (PNFI) was 0.60, and Parsimonious Comparative Fit Index (PCFI) was 0.63, which met the acceptance criteria, and the Root Mean Square Error of Approximation (RMSEA) was 0.10. Goodness of Fit Index (GFI) was 0.88, Comparative Fit Index (CFI) was 0.85, and Incremental Fit Index (IFI) was 0.85 which were found to be acceptable as per the applicable standards. All items had a Cronbach's �� score of .85, which ensured stable reliability. The nurse's health promotion behavior measurement tool developed in this study will be used to measure the nurse's health promotion behavior in terms of nursing practice which will help in understanding the broad contours of this behavior.

• Journal of the Korean Applied Science and Technology
• /
• v.38 no.1
• /
• pp.19-28
• /
• 2021

Corrosion is the degradation of metals by reaction with the environment. It is difficult to completely remove. Corrosion proceeds rapidly after the protective barrier is destroyed, and several reactions occur that alter the composition and properties of the metal surface and local environments, such as diffusion of metal cations into the matrix, the formation of oxides, and local pH changes. The study of corrosion of steel and iron is of theoretical and practical interest and is receiving considerable attention. Acid solutions, which are widely used in industrial pickling, acid descaling, cleaning and acidification of oil wells, require the use of corrosion inhibitors to suppress corrosion attacks on metallic materials. Physical removal of rust requires expensive special equipment, and chemical removal of it can cause corrosion or shorten the life of the metal. In this study, an eco-friendly rust cleaner was developed using cosmetics and food materials by applying the concept of perm reducing agent and chelate, and applied to remove rust from industrial and hot water pipes and various industrial devices. As a result, it was found that rust cleaners remove rust more effectively and safely compared to conventional treatment methods. At the same time, the rust removal efficiency was 1.75 to 2.5 times better for industrial piping and 1.56 to 2.2 times better for boiler hot water than conventional methods.

• Journal of fish pathology
• /
• v.33 no.2
• /
• pp.145-151
• /
• 2020

The whiteleg shrimp Litopenaeus vannamei can survive in a wide range of salinity (1-40 psu). However, such variation, particularly at low salinity (1-5 psu), can affect various physiological changes such as survival rates, non-specific immunity and disease resistance. In this study, growth, non-specific immunity and disease resistance were measured following simultaneous oral feeding and addition of probiotic microbes into culture water for 73 day period. The salinity of the culture water was maintained at 3 psu by periodical salt additions. The result shows that survival rate increased significantly (5.6 vs. 15.4%) after 73 day rearing. Significant increases were identified in reactive oxygen species (ROS) production and phenol oxidase (PO) activity. However, superoxide dismutase (SOD) activity was not influenced. When the shrimp was artificially challenged with Vibrio alginolyticus, slight mortality reduction was observed in the probiotics-treated group (100 vs. 79%). In conclusion, the production of cultured whiteleg shrimp at low salinity might be increased by probiotics survivable at low salinity levels.

• Korean Journal of Remote Sensing
• /
• v.38 no.6_1
• /
• pp.1301-1314
• /
• 2022

Normalized Difference Vegetation Index (NDVI) is utilized as an indicator to represent the vegetation condition on the land surface in various applications such as land cover, crop yield, agricultural drought, soil moisture, and forest disaster. However, satellite optical sensors for visible and infrared rays cannot see through the clouds, so the NDVI of the cloud pixel is not a valid value for the land surface. This study proposed a real-time correction of the underestimation noise for GEO-KOMPSAT-2A (GK2A) daily NDVI and made sure its feasibility through the quantitative comparisons with Moderate Resolution Imaging Spectroradiometer (MODIS) NDVI and the qualitative interpretation of time-series changes. The underestimation noise was effectively corrected by the procedures such as the time-series correction considering vegetation phenology, the outlier removal using long-term climatology, and the gap filling using rigorous statistical methods. The correlation with MODIS NDVI was higher, and the difference was lower, showing a 32.7% improvement compared to the original NDVI product. The proposed method has an extensibility for use in other satellite products with some modification.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.55 no.5
• /
• pp.557-566
• /
• 2022

The Japanese eel Anguilla japonica is a highly valued research object that is important for aquaculture in Asia, including the Republic of Korea. However, few studies have been conducted analyzing parentage using microsatellite markers derived from the Japanese eel. We acquired Japanese eel genome data using next generation sequencing technology, and constructed a draft genome comprising 1,087 Mbp. Using the Simple Sequence Repeat Identification Tool program, 444,724 microsatellites were identified. Of these, 1,842 microsatellites located in the 3' untranslated region, which are stably inherited, were finally selected. Ninety-six primers were selected to validate polymorphism at these microsatellites, and 9 primers were finally identified for multiplex analysis. Using multiplex polymerase chain reaction with three different fluorescence chemistries, we performed parentage analysis of an artificial Japanese eel population. CERVUS software was used to calculate the logarithm of the odds (LOD) scores and the confidence of the parentage assignments. The results presented here show that 83 out of 85 paternity cases were assigned at 95% confidence to a candidate father and mother with LOD scores ranging from 4.79 to 28.2. This study provided a microsatellite marker-based assay for parentage analysis of Japanese eels, which will be useful for selective breeding and genetic diversity studies.

• 한국노년학
• /
• v.41 no.1
• /
• pp.127-147
• /
• 2021

It is critical to secure stable financial resources and efficient financial management for local governments to promote elderly welfare. Using the Fuzzy Set Qualitative Comparative Analysis method, we empirically examined the conditions under which the 17 metropolises and provinces in Korea increase or decrease their budget for elderly welfare. After examining previous studies, socio-economic variables(ratio of elderly people, ratio of elderly welfare recipients), financial variables(financial independence ratio), and political administrative variables (number of regulations on elderly welfare) were included in the analyses to determine the causal conditions of elderly welfare budget per person. Fs/QCA resulted in three combinations of elderly welfare budget per person: first, the combination of low ratio of elderly people, high ratio of elderly welfare recipients, and low number of regulations on elderly welfare; second, the combination of low ratio of elderly welfare recipients, low financial independence ratio, and high number of regulations on elderly welfare; and lastly, the combination of high ratio of elderly people, high ratio of elderly welfare recipients, and low financial independence ratio. Implications for elderly welfare were made considering socio- economic, financial, and political administrative circumstances based on the study results.

• The Korean Journal of Archival Studies
• /
• no.71
• /
• pp.273-309
• /
• 2022

The discussion on local archives management institutions started in the early 2000s and has been steady. In the law, local records management institutions first appeared in 1999, and in 2007, the establishment of local records management institutions by local governments became compulsory. The archival institutions of local government, however, were actually founded in the Gyeongnam Province, 2018, and in the Seoul City, 2019, over 10 years after the revision of the law. And as of 2021, various local governments, including Gyeonggi-do, are conducting research to establish local archives management institutions. This is the time when domestic records management institutions are introduced in earnest. However, it is still unclear how regional archives will operate in practice, particularly how they will accommodate the management of private archives, which has long been regarded as the mission of regional archives. In this thesis, the past discussions on the local record management institutions will be reviewed focusing on private record management. In this regard, it is intended to examine the current state of private records management of local records management institutions through the current status of local records management institutions in operation, and to seek directions for local records management institutions based on this.