• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.2
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• pp.103-111
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• 2010

Objectives : This study was performed to report the effect of oriental medical treatment in the lower back pain(LBP) with amyotrophic lateral sclerosis(ALS). Methods : A 32-years-old man who diagnosed as ALS was admitted with LBP. We treated him by burning acupuncture, herbal medicine, acupuncture, electroacupuncture, moxibustion, cupping therapy and physical therapy from 11th May 2010 to 10th June 2010. Results : After treatment, there was improvement in LBP. Pain Intensity estimated by visual analog scale(VAS) as percentile Pain Intensity Difference(PID), Korean Owestry Disbility Index(KODI) was also improved. Korean version of Amyotrophic lateral sclerosis Functional rating scale-revised(K-ALSFRS-R) shows that the patient's physical ability has been improved. Conclusions : Our study suggests that oriental medical treatment are significantly effective in the LBP due to ALS. And further studies will be aid to identify underlying mechanism of treatment.

• Journal of Gastric Cancer
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• v.7 no.1
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• pp.38-41
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• 2007

Increased risk of gastric cancer has been reported in patients with chronic atrophic gastritis that develops in conjunction with pernicious anemia. We report here a case of a gastric adenocarcinoma associated with pernicious anemia. A 40-year-old female patient had been diagnosed with anemia 6 years earlier at a local hospital. One month ago, she visited our hospital for aggravated dizziness and newly developed epigastric soreness. Her blood hemoglobin level was 4.2 g/dl, and a gastroscopic work-up for anemia discovered a 2.5-cm-sized, slightly elevated mucosal lesion at the anterior wall of the high body in the stomach. The biopsy of this lesion revealed a moderately-differentiated adenocarcinoma. She underwent a total gastrectomy with a Roux en Y esophagojejunostomy with D2 lymph node dissection. The final stage of the gastric carcinoma was identified as T1N0M0. Based on this experience, we recommend that a follow-up gastroscopy be performed in patients with pernicious anemia with atrophic gastritis because of the increased risk of gastric cancer in patients with pernicious anemia.

• Journal of the Korean GEO-environmental Society
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• v.14 no.9
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• pp.31-37
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• 2013

In this study installation diameter, interval, area replacement ratio and ground hardness of applicable ground in C.G.S method should be mastered through surrounding ground by conducting modeling. Optimum artificial neural network was selected through the study of the parameter of artificial neural network and prediction model was developed by the relationship with numerical analysis and artificial neural network. As this result, C.G.S pile settlement and ground settlement were found to be equal in terms of diameter, interval, area replacement ratio and ground hardness, presented in a single curve, which means that the behavior pattern of applied ground in C.G.S method was presented as some form, and based on such a result, learning the artificial neural network for 3D behavior was found to be possible. As the study results of artificial neural network internal factor, when using the number of neural in hidden layer 10, momentum constant 0.2 and learning rate 0.2, relationship between input and output was expressed properly. As a result of evaluating the ground behavior of C.G.S method which was applied to using such optimum structure of artificial neural network model, is that determination coefficient in case of C.G.S pile settlement was 0.8737, in case of ground settlement was 0.7339 and in case of ground heaving was 0.7212, sufficient reliability was known.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.4
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• pp.418-425
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• 2013

This case report describes about recurrent herpetic stomatitis mimicking post-root resection complication. A 49 year-old male patient was diagnosed vertical root fracture of the mesiobuccal root of his left maxillary first molar (#26). The mesiobuccal root was resected following root canal treatment of the same tooth. 19 months later, the patient presented with pain on left hard palate after a barbecue party. Intra oral examination revealed a gum boil-like blister at the hard palate corresponding to the apex of the palatal root of #26. On clinical examination, there was bleeding on probing and the periodontal pocket depth was measured less than 5 mm with no tooth mobility. On a periapical radiograph, periodontal ligament space widening was observed. Tracing the sinus tract with gutta percha cone was attempted, however, it was impossible. Extending the field of vision, small multiple round ulcerations were observed at the palate front which caused pain to the patient. Therefore, the pain was considered a non odontogenic and the patient was referred to the department of oral medicine. The patient was diagnosed recurrent herpetic stomatitis and after 3 days of antiviral medication, the pain and ulceration were subsided.

• Journal of the Korean Geographical Society
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• v.42 no.2 s.119
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• pp.165-176
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• 2007

Absolute age of the deposition of 1.3 km-thick Bunthang sequence within the Skardu intermontane basin of the Central Karakoram was determined using radioactive decay of cosmogonic $^{10}Be$ and $^{26}Al$ burial dating. The Bunthang sequence deposited around 2.65 Ma, which is the oldest glaciation in the region. The timing of deposition of the Bunthang sequence is consistent with the previous suggestion that the basin filling took place between Brunhess and Matuyama chrons. Four major sedimentary facies interfinger within the Bunthang sequence: glacial diamict, lacustrine, fluvial and lacustrine facies upward. This sedimentary distinctiveness and the lack of evidence on the faults for alternative pull-apart basin model around the Bunthang sequence, suggest that the depressional basin was formed by deep subglacial erosion during the exrtensive Bunthang Glacial Stage and subsequently the sediments underlain by basal diamict, was quickly deposited by preglacial and paraglacial processes. Temporary ponding of the Indus River due to tectonic uplift in the downstream or blockage by mass movements might make the basin filing more possible. The hypothesis that the single ice sheet developed on the Tibetan Plateau during the global last glacial cycle should be refuted by the existence of the older extensive Bunthang glacier Furthermore, the extensive glaciation during the early Quaternary (and thus progressive decrease in extent with time) suggests that there may have been significant uplift of the Pamir to the west and Himalaya to the south, which would have reduced the penetration of westerlies and Indian summer monsoon and hence moisture supply to the region.

• Korean Journal of Ichthyology
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• v.19 no.3
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• pp.201-209
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• 2007

The fine structures and histochemical features on the integumentary system of the grass puffer, Takifugu niphobles were examined by means of the light and transmission electron microscopy. Integumentary surface of the grass puffer showed irregular folds in light microscope. The folds of the ventral region are more pronounced than those in the dorsal region. Integumentary system is composed of outer epidermal layer and inner dermal layer. The stratified epidermal layer consists of epithelia, mucous cells, club cells, granular cells and multivacuolar gland. Epithelial cells are classified into superficial, intermediated and basal cell, and free surface of superficial cell is covered with microridges. Glands of the epidermal layer are divided into unicellular and multicellular gland. Mucous cells of multicellular gland contains mucosal materials of neutral glycoprotein. Multivacuolar gland is composed of numerous vacuole cells of about $20{\mu}m$ in axial diameter. Vacuole cells contains a large central vacuole and are connected to another by many desmosomes. The mucous glands and multivacuolar glands are more abundant in ventral region than dorsal integument. The thickness of dermis is more three to five times than epidermis in ventral integument. The collagen fibers, fibrocytes, nerve cells, basal plate of spine and chromatophore are observed in the dermal layer of compact connective tissue.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.4
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• pp.680-684
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• 2004

The hemangioma, a benign proliferation of blood vessel, is the most common tumor of infancy and childhood. In many instances, the lesion probably represents a hamartoma or malformation rather than a true neoplasm. In the oral cavity, common sites are lips, followed by tongue, buccal mucosa and palate. Clinical characteristics appear as a flat or raised reddish-blue lesion and are generally solitary. They are classified on the basis of their histological appearance into capillary, mixed, cavernous or a sclerosing variety. A 6-year-old male of this case was referred to the Department of Pediatric Dentistry, Chonnam National University with a chief complaint of swelling lesion on gingiva. The strawberry appearance mass was detected by clinical examination on attached gingiva at the upper left primary lateral incisor and canine. Surgical excision and biopsy were carried out for histological examination and the lesion was diagnosed with a capillary hemangioma. The risk of recurrence after this therapy is rare, and there is no malignant transformation. Despite their benign origins and behaviour, hemangiomas in the region of oral cavity are always clinically important to the dental profession because of bleeding tendency.

• The Journal of the Petrological Society of Korea
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• v.7 no.1
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• pp.37-52
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• 1998

The granites in the Jeomchon area can be divided into hornblende biotite granite (Hbgr), deformed biotite granite (Dbgr), deformed pinkish biotite granite(Dpbgr), biotite granite (Btgr), and granite porphyry(Gp). These granites show metaluminous, 1-type and calc-alkaine characteristics from their whole-rock chemistry. Hbgr and Dbgr belong to ilmenite-series granitoids, but Gp to magnetite-series. Dpbgr and Btgr show the intermediate nature between ilmenite- and magnetite-series. Tectonic discriminations indicate that Hbgr and Dbgr were formed in active continental margin environment, whereas Dpbgr, Btgr, and Gp in post-orogenic and/or anorogenic rift-related environment. From the Harker diagrams major oxide contents of Hbgr and Dbgr show a continuous variation with $SiO_2$, indicating that they are genetically correlated with each other. On the other hand, any correlation of major oxides variation cannot be recognized among Dpbgr, Btgr and Gp. It seems like that Hbgr and Dbgr were derived from a same parent granitic magma, judging from their occurrence of outcrop, mineral composition as well as whole-rock chemistry. Variation trends of major oxide contents between Hbgr and Baegnok granodiorite are very similar and continuous. If the two granites were derived from a cogenetic magma, there exists a possibility that the granitic bodies had been separated by Btgr and Gp of Cretaceous age. Three stages of the granitic intrusions are understood in the Jeomchon area. After the intrusion of Hbgr and Dbgr during middle to late Paleozoic time, Dpbgr emplaced into the area next, and finally Btgr and Gp intruded during Cretaceous time. Tectonic movement accompanying shear and/or thrust deformation seems likely to have occurred bewteen the intrusions of Dpbgr and Btgr.

• KSBB Journal
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• v.10 no.3
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• pp.283-291
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• 1995

The characteristics of aminopeptidase M(ApM) immobilized covalently on Cellufine Formyl and the continuous production of authentic human growth hormone(hGH) from methionyl human growth hormono(met-hGH) using the column reactor packed with immobilized ApM were investigated. Immobilized ApM with the proportion of 2.3mg ApM per 1g Cellufine Formyl gel had the highest met-hGH conversion activity. The optimum pH(7.0) and temperature($55^{\circ}C$) showed no appreciable difference between free and immobilized enzymes and the optimum temperature in continuous operation of the column reactor was also found to be $55^{\circ}C$. Under the conditions at which met-hGH was converted completely to hGH, the yield and productivity were about 77% and 0.8mg hGH/ml$.$h, respectively. In two column reactors of different sizes, met-hGH was converted to hGH with the same conversion rates and hGH yields at the same space velocities. The half-life of the reactor systems at $45^{\circ}C$ and $55^{\circ}C$ were projected from the continuous operations for 90 days to be 225 days and 81 days, respectively.

• International Journal of Highway Engineering
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• v.9 no.3
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• pp.111-121
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• 2007

During the whole month of December in 2005, Korea experienced both heavy snowfall and freezing temperature in southeast regions, which had caused frost related damages to many pavements laid on top of box culverts. In-situ observation revealed that the formation of ice lenses in subgrade and subsequent unbound layers led to upward heaving and transverse cracks in concrete and asphalt pavements. This has affected the long-term performance of pavements, as well as has threatened drivers' safety for a while. Recently, Korea Expressway Corporation has proposed a design guide to better protect newly constructed unbound pavement layers over culverts from frost heave. A trench drainage system has been selected to effectively draw off water and to alleviate pore-water pressure in soils during the coldest season. This paper presents experimental and analytical backgrounds behind this new design guide. Soil specimens retrieved from the sites are tested to quantify clay content and to estimate the permeability of subgrade. A 2-D ground seepage analysis has been conducted to better understand the changes in pore water pressures as a function of grain size. Finally, an optimum size of trench drainage is determined based on numerical analysis and workability in the field.