• Journal of Animal Science and Technology
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• v.49 no.4
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• pp.437-442
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• 2007

The melanocortin-4 receptor(MC4R) is virtually expressed in all brain regions and plays an important role in energy homeostasis in mammals. MC4R has been intensively studied as a trait gene controlling economically important traits, such as growth and feed conversion, etc. Six hundreds and sixty Duroc pigs were genotyped for the MC4R locus and analyzed their relationships with breeding values for average daily gain(ADG), backfat thickness(BF), days to 90kg(D90) and feed conversion(FC). The estimated genotype frequencies for the all Duroc pigs were: 30.8%, 45.2%, 24.1% for AA, AB and BB genotypes, respectively. The mutant A allele was significantly associated with ADG, D90 and BF whereas no significant relationship was found with FC. The change of gene frequencies by generation was shown in both selected and culled groups. These results indicate that the MC4R polymorphism could be integrated in the present selection program to realize a marker-assisted selection for the growth traits of the Duroc population.

• Journal of Animal Science and Technology
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• v.55 no.3
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• pp.165-171
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• 2013

Genomic relationship matrix (GRM) was constructed using whole genome SNP markers of swine and genomic breeding value was estimated by substitution of the numerator relationship matrix (NRM) based on pedigree information to GRM. Genotypes of 40,706 SNP markers from 448 pure Landrace pigs were used in this study and five kinds of GRM construction methods, G05, GMF, GOF, $GOF^*$ and GN, were compared with each other and with NRM. Coefficients of GOF considering each of observed allele frequencies showed the lowest deviation with coefficients of NRM and as coefficients of GMF considering the average minor allele frequency showed huge deviation from coefficients of NRM, movement of mean was expected by methods of allele frequency consideration. All GRM construction methods, except for $GOF^*$, showed normally distributed Mendelian sampling. As the result of breeding value (BV) estimation for days to 90 kg (D90KG) and average back-fat thickness (ABF) using NRM and GRM, correlation between BV of NRM and GRM was the highest by GOF and as genetic variance was overestimated by $GOF^*$, it was confirmed that scale of GRM is closely related with estimation of genetic variance. With the same amount of phenotype information, accuracy of BV based on genomic information was higher than BV based on pedigree information and these symptoms were more obvious for ABF then D90KG. Genetic evaluation of animal using relationship matrix by genomic information could be useful when there is lack of phenotype or relationship and prediction of BV for young animals without phenotype.

• Korean Journal of Agricultural Science
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• v.42 no.4
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• pp.361-368
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• 2015

This study was to investigate the effect of high energy diet on characteristics of Hanwoo steers distributed by estimated breeding value (EBV). The aim of this experiment was to determine the effect of high energy diet on the high and low beef group distributed by EBV for quality grades. We hypothesized that high energy diet is able to increase quality traits in high EBV groups when fed a high energy diet. A $2{\times}2$ factorial arrangement (High energy, control vs high EBV, low EBV) in a completely random design was used to feed 26 Hanwoo steers. Blood was drawn from each steers from 11 to 28 months. ADG and feed efficiency were not different between high energy and control diet (P>0.05). The level of DMI was greater at calf and early fattening diet in low EBV groups (P<0.05). Serum glucose and tryglyceride conecntrations were increased (P<0.05) by high EBV group from 22 to 28 month old. Serum NEFA concentration were plateau at 24 months at high EBV group and steady reduced by high energy diet (P<0.05). This data indicated that high energy diets increased serum glucose and triglyceride concentrations of high EBV steers at final fattening period.

• 종축개량
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• v.20 no.5
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• pp.12-23
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• 1998

한우개량사업에 있어 종축에 대한 육종가(Breeding Value)의 평가는 아쉽게도 그리 역사가 깊지 않다. 1995년 3월에 축협개량사업본부에서 최초로 종모우 및 종빈우에 대하여 유전능력을 평가한 이래 현재 98년 5월 31일 농촌진흥청 종축개량부, 축협 한우개량부 및 본회와 공동으로 '한우유전능력 평가보고서(제2호)'를 발간하였다. 사실 이 보고서를 통하여 한우농가에서는 용어의 전문성 등으로 직접 활용하기란 어려운 현실이므로 이해하고 활용할 수 있도록 설명코자 한다.

• The Korea Swine Journal
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• v.19 no.10 s.218
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• pp.165-170
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• 1997

• 종축개량
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• v.18 no.3
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• pp.89-94
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• 1996

• The Journal of the Korean bone and joint tumor society
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• v.9 no.2
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• pp.162-168
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• 2003

Purpose: Primary malignant bone tumors are classified with mesenchymal sarcomas (MS) such as osteosarcoma and chondrosarcoma and small round cell sarcomas (SRS) such as Ewing's sarcoma and lymphoma. Radiological examinations for skeletal sarcoma were using MR scan in tubular bone sarcomas and CT scan in flat bone sarcomas recently. Both MR and CT scans show some findings of bone destruction and soft tissue mass but MR scans don't reveal a finding with mineralization relatively. So we investigated bone destructive pattern of skeletal sarcomas on both MR and CT scans for differentiation of MS and SRS. Materials and Methods: There are 28 MS and 26 SRS examined with MR or CT scans. The findings according to bone destructive pattern were divided to eccentric and concentric in 26 cases of tubular bone sarcomas with MR scan and 28 cases of flat bone sarcomas with CT scan. Results: MR images revealed eccentric destruction in 12 cases of 16 MS and concentric in all cases of 10 SRS (p>.01). CT images showed eccentric destruction in 10 cases of 12 MS and concentric bone destruction in 13 cases of 16 SRS (p>.01) Conclusion: The findings divided to eccentric and concentric bone destructive patterns were useful for differential diagnosis of MS from SRS on both MR and CT scans.

• Journal of the Korean Data and Information Science Society
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• v.25 no.4
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• pp.737-743
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• 2014

This experiment was conducted to compare heterogeneity for the variance in dairy cattle population and to induce homogeneity of variance using 502,228 performance test records of dairy cattle. The estimates of heritability for milk yields, fat yields and protein yields were 0.28, 0.26 and 0.24, respectively and the estimate of average breeding value by birth year was lower in HV (heterogenous variance) model than in animal model, collectively. The average breeding values of milk yields, fat yields and protein yields for 545 sire bulls applicable to the criteria of interbull MACE programme were 453.54kg, 10.75kg and 14.33kg, respectively and when the heterogeneity was adjusted they were 432.06kg, 10.15kg and 13.40kg, respectively, which were lower in all milk traits collectively. In animal model, coefficients of phenotypic correlation between dataset I and II were 0.839 in milk yields, 0.821 in fat yields, and 0.837 in protein yields, while in HV model, they were 0.841 in milk yields, 0.820 in fat yields, and 0.836 in protein yields, showing similar results in 2 models. When compared using animal model and HV model, the regression coefficient for ratio of number of daughters by calving year of milk yields increased from 15.157 to 16.105 and that of fat yields increased from =0.227 to =0.196, but that of protein yields decreased from 0.630 to 0.586.

• Food Science of Animal Resources
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• v.25 no.2
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• pp.218-225
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• 2005

This study was performed to determine sequence variation and RFLP of the mt DNA D-loop region using Southern blot hybridization analysis and to develop mt DNA marker affecting milk production traits in Hanwoo cows. The PCR was used to amplify an 1142 bp fragment within the D-loop region of mt DNA using specific primers. Mt DNA were digested with seven restriction enzymes and hybridized using DIG-labeled D-loop probe. The mt DNA RFLP polymorphisms were observed in the four enzymes, BamHI, RsaI, XbaI and HpaII. Nucleotide substitutions were detected at positions 441 (G/C), 469 (T/C), 503 (C/T), 569 (G/A), 614 (C/A) and 644 (C/T) of the mt DNA D-loop region between two selected lines. Significant relationship between the XbaI RFLP type and breeding value was found(p<0.05). Cows with A type had higher estimated breeding values than those with B type (P<0.05) between high and low milk production lines. Therefore, the RFLP marker of mt DNA could be used as a selection assisted tool for individuals with high milk producing ability in Hanwoo.

• 월간낙농육우
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• v.36 no.7
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• pp.125-128
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• 2016

국내 1세대 육종가로서, 38년간 낙농업을 해오면서 두 번의 폐업을 거친 뒤 다시 목장으로 돌아와, 육종가라면 누구나 꿈꾸는 그랜드챔피언에 등극한 경기도 화성의 대원목장 박홍섭 대표(61세, 협회 서울우유연합지회장, 서울우유 발안축산계장). 그는 자신을 어쩔 수 없는 '목장쟁이'라고 한다. 지역 후계농들의 멘토가 되어 스터디그룹을 운영하고, 지역사회 일원으로 어려운 사람들을 위해 나눔을 실천하고 있는 박홍섭 대표를 만나 '건강한 낙농산업 이야기'를 들어봤다.