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Inheritance and Cross Resistance of Bifenazate Resistance in Twospotted Spider Mite, Tetranychus urticae (Bifenazate 저항성 점박이응애의 유전과 교차저항성)

  • Yu Jeong-Soo;Seo Dong-Kyu;Kim Eun-Hee;Han Jong-Been;Ahn Ki-Su;Kim Gil-Hah
    • Korean journal of applied entomology
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    • v.44 no.2
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    • pp.151-156
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    • 2005
  • The development of resistance to bifenazate (resistance ratio of egg=40.3 folds) was found in population of the twospotted spider mite, Tetranychus urticae, collected from rose greenhouses in Chilgok, Gyeongbuk Province in December 2000. This population was selected for 4 years with bifenazate treatment (over 150 times), and showed 248.8 folds increase in resistance as compared to susceptible (S) strain. Inheritance of bifenazate resistant strain (R) and cross resistance of this strain to 9 acaricides were investigated. There were differences of susceptibility in the bifenazate concentration-mortality relationships in F1 progenies obtained from reciprocal cross with the S and R strain $(R{\times}S,\;S{\times}R)$. Degrees of dominance were 0.48 and 0.94 in adult females and eggs of $R{\times}S$ and -0.85 and -0.17 in adult females and eggs of $S{\times}R$, respectively. Inheritance type in the F1 progeny of $R{\times}S$ was incomplete dominant, and F1 progeny of $S{\times}R$ was incomplete recessive. These results suggest that inheritance of bifenazate resistance is controlled by a complete dominance. The R strain exhibited cross resistance to acequinocyl and fenpyroximate in adult females, and amitraz, emamectin benzoate, fenpyroximate, milbemectin, pyridaben and spirodiclofen in eggs. However they showed negatively correlated cross-resistance to emamectin benzoate and milbemectin in adult females, and abamectin in eggs.

Analysis of Heat Transfer Characteristics Based on Design Factors for Determining the Internal Geometry of Metal Insulation in Nuclear Power Plant (원전용 금속단열재의 내부 형상결정을 위한 설계인자 별 열전달 특성 분석)

  • Song, Ki O;Yu, Jeong Ho;Lee, Tae Ho;Jeon, Hyun Ik;Ha, Seung Woo;Cho, Sun Young
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.11
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    • pp.1175-1181
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    • 2015
  • A heat insulating material used in the industrial site normally derives its heat insulating performance by using a low thermal conductivity material such as glass fiber. In case of the metal insulation for nuclear power plant, in contrast, only TP 304 stainless steel foil having high thermal conductivity is the only acceptable material. So, it is required to approach in structural aspect to ensure the insulation performance. In this study, the design factors related to the metal insulation internal structure were determined considering the three modes of heat transfer, i.e., conduction, convection, and radiation. The analysis of heat flow was used to understand the ratio of the heat transfer from each factor to the overall heat transfer from all the factors. Based on this study, in order to minimize the convection phenomenon caused by the internal insulation, a multiple foil was inserted in the insulation. The increase in the conduction heat transfer rate was compared, and the insulation performance under the three modes of heat transfer was analyzed in order to determine the internal geometry.

Cyclic Expression of Cyclooxygenase-l and -2 in Human Endometrium (인간 자궁내막에서 Cyclooxygenase-1과 -2의 주기적 발현 양상)

  • Park, Dong-Wook;Yang, Hyun-Won;Kwon, Hyuek-Chan;Hwang, Kyung-Joo;Yoo, Jung-Hyun;Lee, Chi-Hyeong;Kim, Sei-Kwang;Cho, Dong-Jea;Oh, Kie-Suk
    • Clinical and Experimental Reproductive Medicine
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    • v.25 no.1
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    • pp.25-33
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    • 1998
  • Cyclooxygenase (COX) is an enzyme involved in the conversion of arachidonic acid to prostaglandins (PGs), and exists in two forms, COX-1 and COX-2. COX has been reported to be involved in early implantation by secretion of PGs which causes permeability of vessels and reaction of decidual cells around the implantation site. Recently, in mice and sheep studies, COX-1 and COX-2 expression in the endometrium has been reported to be different according to implantation and stages of the estrous cycle, but expression of COX-1 and COX-2 in human endometrium during the menstrual cycle has not yet been established. The purpose of this study was to observe the variances of COX-1 and COX-2 expression by immunohistochemical staining in endometrial samples obtained from human hysterectomy specimens and biopsies of women of reproductive age according to different stages of the menstrual cycle. Also, we attempted to observe COX-1 and COX-2 expression in the epithelial and stromal cells of the endometrium obtained during the mid-secretory phase, which were cultured separately. COX-2 showed a cyclic pattern of expression according to the different stages of the menstrual cycle and was strongly expressed particularly at the mid-secretory phase which corresponds to the time of implantation. However, COX-1 tended to be increased in the early proliferative, and mid- and late secretory phases, but was also expressed in the whole menstrual cycle showing no particular pattern. In the separately cultured cells COX-1 was expressed in epithilial cells and COX-2 in the stromal cells. The above results suggest that since COX-2 is expressed at the same time as implantation and cultured cells display a specific secretory pattern, COX-2 has inductive endocrine enzyme properties and has an important effect on endometrial cells during implantation. Also, COX-2 expression in endometrial cells may be utilized as a useful marker of endometrial maturation.

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The Reliability and Validity Test of Sasangin Diagnostic Questionnaire for Specialist(SDQ_S) (전문가용 사상체질진단지의 신뢰도와 타당도 검사)

  • Pak, Yun-Seong;kim, Je-Shin;Park, Byung-Joo;Yoo, Jung-Hee;Lee, Jun-Hee;Koh, Byung-Hee;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.28 no.2
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    • pp.110-122
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    • 2016
  • Objectives The purpose of this study was to develop the Sasangin Diagnostic Questionnaire for Specialist(SDQ_S) and to evaluate the reliability and validity of SDQ_S for standardization of sasang constitutional diagnosis by korean medicine Specialist in clinical practice.Methods SDQ_S was developed through discussions of three sasang constitutional medical specialist. We recruited 210 subjects aged from 20 to 70, and conducted the evaluation of SDQ_S and sasang constitutional diagnosis. For the reliability test, internal consistency was examined by calculating the cronbach's α coefficient on 88 items excepted measurements of trunk, and independence and agreement was examined by chi-square test and McNemar test for 84 subjects which retested SDQ_S. For the validity test, discriminant functions was derived from the sample group(105 subjects), and they were applied to the test group(105 subjects). We identified the hit-ratio of SDQ_S in the test group.Results and Conclusions In the reliability test, the cronbach's α coefficient was 0.664 and 87 items(98.9%) have dependent relationships between 1st test and 2nd test. And 39 items(44.3%) have high agreements(0.8≤McNemar), 26 items(29.5%) have common agreements(0.4≤McNemar<0.8). In the validity test, four discriminant variables(Soeum Index, Taeeum Index, Torso Ratio I, Taeyang Index) were selected, and two discriminant functions were derived. Total hit-ratio was 74.2%, and hit-ratio of Taeeumin(76.7%) was higher than that of Soeumin(75.9%) and Soyangin(69.7%). SDQ_S has good reliability and validity for sasang constitutional diagnosis.

The Review of a Standardized Method in Retention-Enema: a Clinical Study (보류관장의 표준화된 방법을 위한 고찰: 임상논문을 중심으로)

  • Song, Eun-Young;Lee, Eui-Ju;Bu, Yong-Min;Shin, Seung-Won;Chai, Kwang-Min;Yoo, Jung-Hee;Kim, Hyo-Jin;Baek, Jong-Heon;Lee, Jun-Hee;Koh, Byung-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.25 no.2
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    • pp.108-114
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    • 2013
  • Objectives This study was aimed to review a standardized method of retention enema by extracting elements associated with methods of retention enema from papers involved. Methods 1) Data sources : Retrieval was made, using 'Enema' or 'Retention Enema' as search words in MEDLINE, The Cochrane Library, KISS, RISS, and NDSL DB. 2) Study selection : Two authors excluded irrelevant papers and chose qualified abstracts in the rest of the papers. The chosen studies were reviewed fully by the authors so that they could screen the significant papers based on the exclusion criteria. 3) Data extraction : Data on the total number of subjects, the target disease, the type, quality, length, diameter of catheter, the insertion length of catheter, the sample, the sample volume, the process of retention enema and the number of performing retention enema were extracted from the selected studies. Results & Conclusions The retention enema can be applied to gastrointestinal diseases, genitourinary diseases, metabolic diseases such as hypertension and diabetes, headaches and neurological disorders. The standardized treatment method is as following: 1) inserting a rental tube of 18-28 Fr that measures 20 to 30 cm into the patient's anus, 2) injecting herbal medicines which have purgative action or benefit on stomach and intestinal tract at the rate of 4 ml/min, and 3) holding them for 10 to 15 minutes.

Development of Clinical Practice Guidelines for Sasang Constitutional Medicine Symptomatology - Purpose, Development Strategy and Procedure - (사상체질병증 임상진료지침 개발 연구 - 목적, 개발 전략 및 절차 -)

  • Kim, Je-Shin;Hwang, Min-Woo;Lee, Jun-Hee;Lee, Eui-Ju;Koh, Byung-Hee;Yoo, Jung-Hee;Bae, Na-Young;Kim, Yun-Hee;Bae, Hyo-Sang;Joo, Jong-Cheon;Park, Hye-Sun;Shin, Mi-Ran;Yoo, Jun-Sang
    • Journal of Sasang Constitutional Medicine
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    • v.25 no.1
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    • pp.23-33
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    • 2013
  • Objectives This study was aimed to develop the clinical practice guidelines, which focuses on Sasang Constitutional Medicine symptomology. By developing clinical practice guidelines, we should present prevention, diagnosis, treatment and assessment of Sasang Constitutional Medicine. Methods We used the method of University of Michigan Health System Guidelines model. Electronic databases including English, Korean databases were systematically searched for clinical articles investigating Sasang Constitutional Medicine symptomology up to March 2010. And "Donguisusebowon-ShinChukbon" was basically used to develop clinical guidelines. Results and Conclusions 12,694 Articles were reviewed. Only 25 articles described adequate methods of this study. Using clinical practice guidelines, we can manage th quality of medicine, emphasis treatment appropriacy and educate patients and doctors. Finally We can get the Sasang Constitutional Medicine standardization and socioeconomic benefit.

A study on AI Education in Graduate School through IPA (대학원 인공지능교육의 방향 탐색: IPA를 활용하여)

  • Yoo, Jungah
    • Journal of The Korean Association of Information Education
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    • v.23 no.6
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    • pp.675-687
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    • 2019
  • As interest in artificial intelligence increases, each university has been establishing a special graduate school with artificial intelligence major, and recently, the Korea government has established various support policies for artificial intelligence education. However, each university has a lot of difficulties because it has little experience in operating graduate education with the latest field of artificial intelligence and it is not easy to find experts. In this study, the response of graduate school students majoring in artificial intelligence was analyzed using IPA technique, and the direction of education of graduate school artificial intelligence major was searched. Among the 40 items surveyed by IPA, 12 items such as systematization of artificial intelligence curriculum, progress of class considering learning level, improvement of academic relations with guidance professors were extracted as items to be improved first. On the other hand, 8 items such as assistant capacity, and relationship with colleagues were overloaded, and twelve items such as instructor's lecture competency, appropriateness of educational contents, learner's artificial intelligence skills and knowledge, and attitude acquisition were to be maintained. In addition, eight items such as convergence education curriculum and diversity of education methods were all low in importance and performance. It is suggested that AI graduate school should be divided into two tracks(technical specialization, convergence expansion) by educational goal, and each track should be conducted by level-specific educational contents and methods suitable for student level. The curriculum should be elaborate and systematic to acquire AI knowledge, skills, and attitudes, and should have an individualized guidance system centered on excellent faculty members.

Comparative esthetic evaluation of anterior zone with immediate, early, and delay implantation (전치부 영역 임플란트의 식립 시기에 따른 심미적 평가)

  • Kim, Jung-Hwa;Seo, Seong-Yong;Kim, Na-Hong;Yu, Jung-Hyun;Lee, Dong -Woon
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.26 no.1
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    • pp.17-23
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    • 2017
  • Purpose: This retrospective study is to evaluate whether the timing of implant placement and the result of esthetic outcomes are related. Materials and Methods: Among the patients who had undergone single implant surgery on anterior area from 2010 to 2013 in Veterans Health Service Medical Center, 34 implants in 27 patients (24 male and 3 female) were selected and categorized into 3 groups according to the timing of placement, which are group D (Delay), group E (Early) and group I (Immediate). Aesthetic indices used included the Pink Esthetic Score (PES). It has 7 variables scores, such as mesial papilla, distal papilla, a level of soft-tissue margin, soft-tissue contour, alveolar process, soft-tissue color, and soft-tissue texture. Each variable ranges from 0 to 2, therefore total 14 points are highest. All patients were received by regular follow-up at least 1-year. One examiner measured PES on the intraoral photos. Each patient was considered as a statistical unit for statistical analysis. Statistical analyses were performed using a commercially available statistical software (SPSS Statistics 21.0, IBM Corp., Armonk, NY, USA). Kruskal-Wallis test was used for inter-group comparisons. Statistical significance was set at P<0.05. Result: Mean score in Group D, Group I, and Group E were $11.5{\pm}1.5$, $11.4{\pm}1.8$, and $11.3{\pm}1.8$ respectively. In Kruskal-Wallis test, there are no differences (P=0.989). Conclusion: In this limited study suggests that clinical aesthetic results can be achieved with all treatment protocols. Finally, various factors can be considered to produce the esthetic results.

Cycloaddition of Carbon Dioxide to Allyl Glycidyl Ether Using Silica-supported Ionic Liquid as a Catalyst (실리카에 고정화된 이온성액체를 촉매로 이용한 알릴글리시딜에테르와 이산화탄소의 부가반응)

  • Shim, Hye-Lim;Lee, Mi-Kyung;Yu, Jeong-In;Park, Dae-Won
    • Clean Technology
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    • v.14 no.3
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    • pp.166-170
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    • 2008
  • In this study, imidazolium salt ionic liquid on amorphous silica was prepared and its catalytic performance in the cycloaddition of $CO_2$ with allyl glycidyl ether (AGE) to produce heterocyclic carbonate was investigated. The ionic liquid was generated on chloropropyl functionalized silica through the immobilization of imidazole. The prepared catalyst was characterized using a number of instrumental analysis including XRD, BET, $^{29}Si$ MAS-NMR and SEM. $^{29}Si$ MAS-NMR showed that the ionic liquid formed adduct with the chloropropyl groups attached to the silica surface. The immobilized ionic liquid showed very good catalytic activity for the cycloaddition of $CO_2$ with AGE, showing 55-61% of AGE conversion with over 85% of the carbonate selectivity at $80-120^{\circ}C$. Its AGE conversion and selectivity to the carbonate were even higher than the homogeneous analog, 1-n-butyl-3-methyl imidazolium bromide (BMImBr).

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Absorption Characteristics of Carbon Dioxide by Water-lean Diethylenetriamine Absorbents Mixed with Physical Solvents (물리 흡수제를 포함한 디에틸렌트리아민(Diethylenetriamine) 저수계 흡수제에서의 이산화탄소 흡수 특성)

  • Lee, Hwa Young;Seok, Chang Hwan;You, Jong-Kyun;Hong, Yeon Ki
    • Clean Technology
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    • v.24 no.1
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    • pp.50-54
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    • 2018
  • In this work, N-methyl-2-pyrrolidone (NMP) was added into diethylenetriamine (DETA) aqueous solution for high $CO_2$ loading via phase splitting of absorbents during $CO_2$ absorption. Immiscible two phases were formed in the range of more than 30 wt% of NMP in 2 M DETA + NMP + water absorbents because of low solubility of DETA-carbamate in NMP solution. As the composition of NMP in the absorbents increased, the difference of $CO_2$ loading between each phase increased and the volume of bottom phase decreased. In $CO_2$ absorption in packed column by 2 M DETA + NMP + water absorbents, the absorption rate decreased in the range of more than 40 wt% of NMP. It is due to the increasing of mass transfer resistance in liquid film of absorbents at the high concentration of NMP. DETA + NMP + water absorbent is expected as the promising one for reducing the regeneration energy of absorbents according to volume reduction of $CO_2-rich$ phase.