• Title/Summary/Keyword: 유사도 질의

Search Result 1,858, Processing Time 0.032 seconds

Immunological Characterization and Localization of the Alcohol-dehydrogenase in Streptococcus pneumoniae (폐렴구균 알코올탈수소효소의 세포 특이성 및 세포내 분포)

  • 권혁영;박연진;표석능;이동권
    • Korean Journal of Microbiology
    • /
    • v.37 no.3
    • /
    • pp.221-227
    • /
    • 2001
  • Heat shock proteins serve as chaperone by preventing the aggregation of denatured proteins and promote survival of pathogens in harsh environments. In bacteria, ethanol shock induced the major chaperone GroEL and DnaK, but in Streptococcus pneumoniae, it induced neither GroEL nor DnaK but alcohol dehydrogenase (ADH). In this study, ADH gene encoding a 104-kDa (p104) protein was identified and characterized. The deduced amino acid sequence of pneumococcal ADH shows homology with other members of the ADH family, and particularly with Entamoeba histolytica ADH2 and E. coli ADH. S. pneumoniae adh is composed of 883 amino acids and its estimated isoelectric point is 6.09. Although ADH is conserved between S. pneumoniae and E. coli, immunoblot analysis employing antisera raised against pneumococcus ADH demonstrated no cross-reactivity with ADH analog in Eschericha coli, Staphylococcus aureus and human HeLa cells. Also secretion of ADH was demonstrated by subcellular fractionation and immunoblot analysis of proteins. These results suggest that S. pneumoniae ADH could be a highly feasible candidate for both diagnostic marker and vaccine.

  • PDF

The Design and Implementation of a Content-based Image Retrieval System using the Texture Pattern and Slope Components of Contour Points (턱스쳐패턴과 윤곽점 기울기 성분을 이용한 내용기반 화상 검색시스템의 설계및 구현)

  • Choe, Hyeon-Seop;Kim, Cheol-Won;Kim, Seong-Dong;Choe, Gi-Ho
    • The Transactions of the Korea Information Processing Society
    • /
    • v.4 no.1
    • /
    • pp.54-66
    • /
    • 1997
  • Efficient retrieval of image data is an important research issue in multimedia database. This paper proposes a new approach to a content-based image retrieval which allows queries to be composed of the local texture patterns and the slope components of contour points. The texture patterns extracted from the source image using the graylevel co-occurrence matrix and the slope components of contour points extracted from the binary image are converted into a internal feature representation of reduced dimensionality which preserves the perceptual similarity and those features can be used in creating efficient indexing structures for a content-based image retrieval. Experimental results of the image retrievalare presented to illustrate the usefulness of this approach that demonstrates the precision 82%, the recall 87% and the average rang 3.3 in content-based image data retrieval.

  • PDF

Studies on the Application of the Spent Alkaline Manganese Batteries Powder as an Adsorbent for Nickel Ion (폐(廢)알칼리망간전지(電池) 분말(粉末)의 니켈 이온 흡착제(吸着劑)로서의 활용(活用)에 관한 연구(硏究))

  • Baek, Mi-Hwa;Kim, Dong-Su;Sohn, Jeong-Soo
    • Resources Recycling
    • /
    • v.17 no.2
    • /
    • pp.63-69
    • /
    • 2008
  • The adsorption features of $Ni^{2+}$ onto spent alkaline manganese batteries powder have been investigated with the adsorbent dose, initial concentration of adsorbate and temperature as the experimental variables. The adsorption reaction of $Ni^{2+}$ ion followed the pseudo-second order rate model, and the adsorption rate constants($k_2$) decreased with increasing initial concentration of nickel ion. The equilibrium adsorption data were fitted to the Langmuir and Freundlich models. The Freundlich model represents the equilibrium data better than the Langmuir model in this initial adsorbate concentration range. As the temperature increased, the adsorbed amount of nickel ion at equilibrium was also increased, which indicated that the adsorption reaction was endothermic. Based on the experimental results obtained along with temperatures, thermodynamic parameters such as ${\Delta}H^{\circ},\;{\Delta}G^{\circ},\;and\;{\Delta}S^{\circ}$ were calculated.

One-Class Classification Model Based on Lexical Information and Syntactic Patterns (어휘 정보와 구문 패턴에 기반한 단일 클래스 분류 모델)

  • Lee, Hyeon-gu;Choi, Maengsik;Kim, Harksoo
    • Journal of KIISE
    • /
    • v.42 no.6
    • /
    • pp.817-822
    • /
    • 2015
  • Relation extraction is an important information extraction technique that can be widely used in areas such as question-answering and knowledge population. Previous studies on relation extraction have been based on supervised machine learning models that need a large amount of training data manually annotated with relation categories. Recently, to reduce the manual annotation efforts for constructing training data, distant supervision methods have been proposed. However, these methods suffer from a drawback: it is difficult to use these methods for collecting negative training data that are necessary for resolving classification problems. To overcome this drawback, we propose a one-class classification model that can be trained without using negative data. The proposed model determines whether an input data item is included in an inner category by using a similarity measure based on lexical information and syntactic patterns in a vector space. In the experiments conducted in this study, the proposed model showed higher performance (an F1-score of 0.6509 and an accuracy of 0.6833) than a representative one-class classification model, one-class SVM(Support Vector Machine).

A Web-based Virtual Experiment Kit for Digital Logic Circuits Using Java Applet (자바 애플릿을 이용한 웹 기반 디지털 논리회로 가상실험키트)

  • Kim Dong-Sik;Kim Ki-Woon
    • Journal of Engineering Education Research
    • /
    • v.6 no.2
    • /
    • pp.5-14
    • /
    • 2003
  • In this paper, we developed an efficient virtual experiment kit with creative and interactive multimedia contents, which can be used to enhance the quality of education in the area of digital logic circuits. Since our virtual experiment kit is implemented to describe the on-campus laboratory, the learners can obtain similar experimental data through it. Also, our web-based virtual experiment kit is designed to enhance the efficiency of both the learners and the educators. The learners will be able to achieve high learning standard and the educators save time and labor. The virtual experiment is performed according to the following procedure: (1) Circuit Composition on the Bread Board (2) Applying Input Voltage (3) Output Measurements (4) Checkout of Experiment Results. Furthermore, the circuit composition on the bread board and its corresponding online schematic diagram are displayed together on the virtual experiment kit for the learner's convenience. Finally, we have obtained several affirmative effects such as reducing the total experimental hours and the damage rate for experimental equipments and increasing learning efficiencies as well as faculty productivity.

Splog Detection Using Post Structure Similarity and Daily Posting Count (포스트의 구조 유사성과 일일 발행수를 이용한 스플로그 탐지)

  • Beak, Jee-Hyun;Cho, Jung-Sik;Kim, Sung-Kwon
    • Journal of KIISE:Software and Applications
    • /
    • v.37 no.2
    • /
    • pp.137-147
    • /
    • 2010
  • A blog is a website, usually maintained by an individual, with regular entries of commentary, descriptions of events, or other material such as graphics or video. Entries are commonly displayed in reverse chronological order. Blog search engines, like web search engines, seek information for searchers on blogs. Blog search engines sometimes output unsatisfactory results, mainly due to spam blogs or splogs. Splogs are blogs hosting spam posts, plagiarized or auto-generated contents for the sole purpose of hosting advertizements or raising the search rankings of target sites. This thesis focuses on splog detection. This thesis proposes a new splog detection method, which is based on blog post structure similarity and posting count per day. Experiments based on methods proposed a day show excellent result on splog detection tasks with over 90% accuracy.

Isolation and Optimal Culture Conditions of Prodigiosin-like Pigment Produced by Zooshikella sp. JE-34 (Zooshikella sp. JE-34가 생산하는 Prodigiosin계 색소의 분리 및 최적 배양조건)

  • Kim, Ju-Sang;Kim, Man-Chul;Lee, Kyeong-Jun;Heo, Moon-Soo
    • Microbiology and Biotechnology Letters
    • /
    • v.37 no.3
    • /
    • pp.219-225
    • /
    • 2009
  • A bacterial strain, JE-34, producing a high concentration of red pigment was isolated from a sediment in East China Sea. It was identified as Zooshikella sp. JE-34 based on the 16S rRNA gene sequence analysis. The red pigment was purified by solvent extraction and HPLC was identified as prodigiosin-like compound. Nutritional and cultural conditions were optimized for the production of prodigiosin-like pigment in the flask level. Optimal culture conditions were at initial medium pH $6.0{\sim}7.0$, $30^{\circ}C$ and 4 days incubation. For carbon and, nitrogen sources were soluble starch and malt extract.

An Analysis of Ortholog Clusters Detected from Multiple Genomes (다종의 유전체로부터 탐지된 Ortholog 군집에 대한 분석)

  • Kim, Sun-Shin;Oh, Jeong-Su;Lee, Bum-Ju;Kim, Tae-Kyung;Jung, Kwang-Su;Rhee, Chung-Sei;Kim, Young-Chang;Cho, Wan-Sup;Ryu, Keun-Ho
    • Journal of KIISE:Databases
    • /
    • v.35 no.2
    • /
    • pp.125-131
    • /
    • 2008
  • It is very useful to predict orthologs for new genome annotation and research on genome evolution. We showed that the previous work can be extended to construct OCs(Ortholog Clusters) automatically from multiple complete-genomes. The proposed method also has the quality of production of InParanoid, which produces orthologs from just two genomes. On the other hand, in order to predict more exactly the function of a newly sequenced gene it can be an important issue to prevent unwanted inclusion of paralogs into the OCs. We have, here, investigated how well it is possible to construct a functionally purer OCs with score cut-offs. Our OCs were generated from the datasets of 20 procaryotes. The similarity with both COG(Clusters of Orthologous Group) and KO(Kegg Orthology) against our OCs has about 90% and inclines to increase with the growth of score cut-offs.

Paradraconema jejuense, a New Species of Genus Paradraconema (Nematoda: Draconematidae) from Korea (곁도마뱀선충속 (선형동물문: 도마뱀선충과)의 해양 선충류 1신종)

  • Rho Hyun Soo;Kim Won
    • Animal Systematics, Evolution and Diversity
    • /
    • v.21 no.1
    • /
    • pp.81-91
    • /
    • 2005
  • A new species of draconematid nematode, Paradraconema jejuense n. sp., is described from the shallow sublittoral coarse sediments of Jeju Island, Korea. Paradraconema jejuense n. sp. is most similar to P. antarcticum Allen and Noffsinger, 1978 in having similar habitus (long slender body) and amphideal fovea (doubled elongate spiral in male and circular spiral in female), but is distinguished by the following characteristics: larger number of posterior sublateral adhesion tubes (10 in male and 11-12 in female) and subventral adhesion tubes (16 in male and 17-18 in female), fewer cephalic acathiform setae on rostrum (a pair of small cephalic acathiform setae in both sexes), the absence of eye-spots, and the presence of a differentiated lateral field in mid-body region. This is the first taxonomic report on Paradraconema species from Korea.

The Comparative evaluation of cultural contents preference for active seniors' enjoyment (액티브시니어의 문화향유 콘텐츠 선호도 비교평가)

  • Kim, Woo-Seop;Shin, Young-Seok;Shin, I-Su;Kim, Kyu-Ho;Jung, Duk-Young
    • Journal of rehabilitation welfare engineering & assistive technology
    • /
    • v.12 no.1
    • /
    • pp.20-28
    • /
    • 2018
  • In this research, for the smooth cultural life of seniors, we recruit 92 smart seniors (male: 22, female: 70) and survey their preferred content sub-genre. The survey is mainly based on the two devices (PC, Smartphone) to be used. As a result of the study, there was a little difference in preference on the web pages between both devices, the video contents showed the similar preference, regardless of the device. Also, sub-genres surveyed show higher correlations with similar sub-genres in other content genres. So, If the result of this study is reflected in the development of cultural contents and the composition of content pages, it will be helpful for senior to enjoy the improved cultural life by lowering entry barriers accessing digital media contents.