• Korean Journal of Food Science and Technology
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• v.46 no.4
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• pp.516-521
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• 2014

The mechanisms underlying the refractory effects of flutamide, a first-line oral anti-androgen drug, have not been entirely elucidated. In the present study, we investigated the mechanism of flutamide-induced hormone-refractory prostate cancer cell growth and its modulation by resveratrol, a phytoalexin present in grapes. Resveratrol significantly attenuated interleukin 6 (IL-6)-induced signal transducer and activator of transcription 3 (STAT3) transcriptional activity and dihydrotestosterone (DHT) or IL-6-induced prostate-specific antigen (PSA) transcriptional activity. Furthermore, compared to treatment with DHT or IL-6 alone, combination treatment of cells significantly increased PSA transcriptional activity, and resveratrol markedly diminished DHT plus IL-6-induced STAT3 and PSA transcriptional activities. Thus, the inhibitory effects of resveratrol on IL-6-, DHT-, and flutamide-induced hormone-refractory prostate cancer cell growth are partly mediated by the suppression of STAT3 reporter gene activity, suggesting that resveratrol represents a promising therapy for prostate cancer.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.6
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• pp.1229-1234
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• 2018

In this paper, a fire prevention system based on a broadband powerline communication (PLC) system is implemented and a demonstration experiment is carried out to prevent from or promptly dealing with possible fires within the nacelle of a wind turbine generator system (WTGS). For this purpose, an inductive coupler having satisfactory attenuation characteristic in the frequency region for high-speed PLC is also manufactured. It is confirmed that the implemented system can monitor the environmental change inside the nacelle in real time by transmitting various information obtained by the sensors such as temperature, flame, and smoke sensor installed in the nacelle and thermal image recorded by a thermal camera to the ground control center through the PLC system. Therefore, it is, considered that the implemented system will significantly improve the reliability of the fire monitoring and prevention system of the WTGS in conjunction with the existing safety system.

• Journal of Radiation Protection and Research
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• v.21 no.3
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• pp.167-173
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• 1996

The calibration method for the detection efficiency of solid state track detector to alpha is presented, and the detection efficiency of CN-85 and LEXAN to alpha is measured by this method. The results are 97% and 57% in CN-85 and LEXAN, respectively. The reason for a better result in CN-85 in not only the high sensitivity but also the low energy dependency with comparing for LEXAN. The peak detection efficiency is 3MeV and 1.8MeV in CN-85 and LEXAN, respectively.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.6
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• pp.1478-1485
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• 1993

A shape optimization problem is formulated to determine the optimal position of heating lines in a compression molding die. The objective of the problem is that the cavity surface would be maintained by a prescribed uniform temperature. A boundary integral equation for the sensitivity of the temperature in terms of hole position is derived using the method of shape design sensitivity analysis. The boundary element method is employed to analyze the temperature and sensitivity field of the die. The sensitivity calculation algorithm is incorporated in an optimization routine. To demonstrate a numerical implementation, an example problem arising in thermal design of a compression molding die is dealt with, showing that the number of heating lines chosen for the die strongly affects the ultimate uniformity of the cavity surface temperature.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.4
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• pp.562-569
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• 2001

This paper presents the optimum design method for T-shaped microstrip-line-fed slot antennas on various substrates. Since the impedance bandwidth of the antenna depends highly on the vertical offset position and the length of horizontal strip conductor, we derived the formulas regarding these design parameters to get the maximum bandwidth. The formulas can compute the offset position and the length of horizontal strip conductor for any given substrate parameters. We compared the results obtained by using these design formulas and the one obtained by the simulation for each slot width, and it showed very good agreement.

• Proceedings of the KIPE Conference
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• 2008.06a
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• pp.326-328
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• 2008

본 논문의 목표는 실제 시스템과 가장 유사한 이중여자 유도발전기(Doubly-Fed Induction Generator)의 시뮬레이터를 구현하고 실험을 통해서 그것을 검증하는 것이다. 바람의 속도를 2D 룩업 테이블을 이용하여 데이터화 한 후 터빈 모델의 입력으로 인가한다. 터빈 모델의 파라미터는 실험용 이중여자 유도발전기의 것과 동일하게 설정하여 실제 시스템과 유사하게 하였다. 지금까지는 이중여자 유도발전기를 모사하기 위하여 매트랩(Matlab) 등을 이용하였지만 실제와 다소 다르다는 문제와 구현하기 힘들다는 문제를 가지고 있었다. 하지만 본 논문에서는 심플로러(Simplorer)를 이용하여 쉽고 정확한 시뮬레이터를 구현하였다. 터빈과 이중여자 유도발전기는 기어를 이용하여 직결함으로써 실제 시스템과 매우 가깝게 모사하였으며 이중여자 유도발전기의 회전자를 여자시키기 위해 이산 캐리어 변조 방법을 이용하여 매트릭스 컨버터를 구동하였다. 그리고 실험을 통해서 시뮬레이터의 결과와 실험 결과의 비교 및 검증을 한다. 궁극적으로 어떤 지역의 바람의 품질과 발전량 등 중요한 정보를 얻기 위해 실제 크기의 발전기를 설치하지 않고 본 논문에서 개발한 시뮬레이터를 이용하여 쉽게 그 정보들을 얻을 수 있다.

• Korean Journal of Food Science and Technology
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• v.44 no.6
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• pp.759-762
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• 2012

Egg allergies have been reported as one of the most prevalent food hypersensitivities in the pediatric population. One of the major egg allergens is ovalbumin (OVA), which is the major protein in the egg whites. Phenethyl isothiocyanate (PEIC) from cruciferous vegetables has an effect on anti-inflammatory therapy. In the present report, we show that PEIC inhibits the nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation induced by OVA. PEIC also inhibits the OVA-induced inducible nitric oxide synthase (iNOS) expression and nitrite production. However, PEIC did not suppress the cyclooxygenase-2 (COX-2) expression induced by OVA. These results suggest that PEIC has the specific mechanism for anti-inflammatory responses and efficient anti-allergic activities.

• The Journal of Natural Sciences
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• v.12 no.1
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• pp.41-48
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• 2002

Atomic coherences can be induced via atom-light interaction and can exhibit new interesting phenomena. Electromagnetically-induced-absorption (EIA) is one of such phenomena where the absorption of probe beam is increased due to the presence of strong coupling beam. EIA can be observed in multiple-V type atomic systems. This paper present a method to study EIA when the frequencies of probe beam and coupling beam are both near resonant to the same transition line. Time-varying interaction Hamiltonian was introduced and density matrix equations were solved and the amplitude of oscillations was used to calculate the EIA.

• Journal of Mushroom
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• v.2 no.4
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• pp.184-191
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• 2004

Mutual growth limitation was observation when the two antagonistic fungi was come in contact with each other. Brown line was formed 2day after contact with Trichoderma spp., and then, green spores formed overnight. The laccase activity of L. edodes was stimulated when this fungus wsa co-incubated with Trichoderma spp. for a few days in liquid media. In sawdust-rice bran nixtures, outstanding broun line developed when the two antagonistic fungi co-cultured. The pH of the substrates changed from 5.5 to 4.5 after overgrowth, suggesting a difference in the degradation ability and the preference of the two fungi for the lignocellulose material.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.9
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• pp.1141-1145
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• 2014

When the stator windings of 3 phase induction motors are in wrong condition, the mutual inductive responses between windings can be utilized for the purpose of diagnosing motors in that fault windings affect even the responses by DC excitation. Three phase induction motors are supposed to generate consistent inductive voltages at the remaining windings when exciting DC current is given to one of 3 windings, while the inconsistence of their voltages indicates the existence of disorder at electric motors. This study describes how the exciting current to one of three windings cause the other windings to create induced voltages, analyzing responses by transfer functions, and discloses whether or not the balance relation at two windings is normal in the way of measuring the differential voltage of their outputs. For experiment, common analog multi-testers is used for applying exciting current and measuring the output signal to confirm whether the proposed method is useful enough to be able to discriminate wrong polarities of windings onboard vessels including also the case of exciting current by AC.