• Clinical and Experimental Pediatrics
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• v.50 no.10
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• pp.987-994
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• 2007

Purpose : This study investigated the clinical significance of AN in children and adolescents with obesity induced metabolic complications. Methods : Forty-nine patients who had obesity induced metabolic complications were participated in this cross-sectional study. Obesity induced metabolic complications are as follows: hypertension, dyslipidemia, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), nonalcoholic steatohepatitis (NASH), homeostasis model assessment of insulin resistance (HOMA-IR)>3.16. Clinical characteristics, such as, age, percentage-weight-for-height (PWH), pubertal status, blood pressure (BP), fasting plasma insulin level, fasting and post-oral glucose tolerance test 2-hour glucose levels, liver function test, lipid profile, HOMA-IR were compared according to the presence of AN. Results : Sixty-five percent of patients had AN, 57.1% NASH, 57.1% dyslipidemia, 55.1% hypertension, 46.9% IFG, 24.5% HOMA-IR>3.16 and 16.2% IGT. The patients who were moderately to severely obese with AN had higher incidence of IGT and HOMA-IR>3.16. The patients with AN had significantly higher diastolic BP ($79.4{\pm}6.9$ vs $75.4{\pm}5.6mmHg$), fasting levels of plasma insulin ($10.6{\pm}6.0$ vs $6.2{\pm}5.4{\mu}IU/mL$), HOMA-IR index ($2.6{\pm}1.4$ vs $1.4{\pm}1.3$) and PWH ($42.4{\pm}13.0$ vs $34.3{\pm}1.8%$). The increasing tendency for the presence of AN was significantly related to the cumulative number of obesity induced metabolic complications. Binary logistic regression analysis revealed that the presence of AN was significantly associated with fasting plasma insulin level, PWH and IFG. Conclusion : AN could be useful as a clinical surrogate of obesity induced metabolic complications.

• Journal of Korean Society for Geospatial Information Science
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• v.24 no.4
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• pp.47-58
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• 2016

The purpose of this study was to select the sectoral vulnerable areas index in welfare field and analyze the socially vulnerable areas from comprehensive analysis. For this study, preceding research and theoretical background were reviewed. Through this, we selected for the analysis index and criteria, and data corresponding to the index are collected. Based on the index and criteria, the data analysis was performed in Seoul Metropolitan City selected as the spatial extent of this study. From the results of analysis, the sectoral lower rank 10% of social vulnerable areas was determined. In addition, Junggu, Yongsangu, and Seodaemungu from the comprehensive analysis of individual vulnerable areas were derived as a final vulnerable areas. In particular, Junggu was weak in all sectors; Yongsangu was in the medical sector; and Seodaemungu was poor in housing and education. Lower vulnerability index of all sectors (energy, housing, medical, transportation, and education) in 1st, 2nd, and 3rd residential areas by examining use zoning was showed. From the results of this study, we can expect time and labor saving of policy support in public sector.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4621-4631
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• 2015

The purpose of this study is to find the grounds for nursing students and teaching professors to confirm the importance of planning and preparing academic careers according to proper time management by determining the learning style exactly for themselves. For this purpose we investigated the learning style and time management behavior of the nursing student in university. The data was collected for 1 months from Nov. 1 to Dec. 2, 2013 in four universities which located in D city and C province. The research tool were used to measure of the learning style, time management behavior and self-directed learning. The participants were 246 nursing students at university who understand the purpose of study and agree to answer it. The data was analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation, stepwise regression using the IBMSPSS/WIN 19.0 program. The result of this study was that the predicting factors for self-directed learning were time management behavior(${\beta}=.629$, p<.001) and adjustment to university life(${\beta}=.153$, p<.001). The variables explained the self-directed learning by 51.4%. This study shows that professors have to encourage students to realize the importance of effective time management for planning, performing and evaluating the academic career for themselves and take into account the related programs about self-directed learning.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.1
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• pp.129-133
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• 2013

Hot pepper (Capsicum annum L.) is one of the most important ingredients in Asian food. The capsaicinoids, capsaicin and dihydrocapsaicin are responsible for more than 90% of the pepper's pungency. The objective of this study was to determine the amounts of these two major capsaicinoids in hot peppers cultivated from different regions in Korea. Peppers (Geumgochu) cultivated in 24 different regions of Korea were collected in 2011. The capsaicinoids of these plants were extracted with methanol and determined quantitatively by HPLC with a fluorescence detector. The capsaicinoid value ranged from 22.4 mg/100 g to 119.1 mg/100 g depending upon different regions. The average capsaicinoid content of the peppers from Gangwon and Gyeonggi was 66.73 mg/100 g, and the content from Jeonbuk and Jeonnam was 50.34 mg/100 g. However, average capsaicinoid content from these four different cultivation regions were not significantly different. Finally, analytical method validation parameters such as recovery, reproducibility, repeatability, were calculated to ensure the method's validity.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.10
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• pp.1525-1532
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• 2013

The objective of this study was to investigate the effect of hot water extract from Cornus walteri Wanger (CWE) on tert-butyl hydroperoxide (TBHP)-induced oxidative stress in HepG2 cells. Generation of reactive oxygen species (ROS), concentrations of cellular lipid peroxidation products and reduced glutathione, and antioxidant enzyme activity were used as biomakers of cellular oxidative status. Cells pretreated with CWE (25~200 ${\mu}g/mL$) showed an increased resistance to oxidative stress in a dose-dependent manner, as revealed by a higher percentage of surviving cells compared to control cells. ROS generation induced by TBHP was significantly reduced when cells were pretreated with 200 ${\mu}g/mL$ CWE for 4 h. Pretreatment with CWE (5~50 ${\mu}g/mL$) prevented the decrease in reduced glutathione and the increase in malondialdehyde and ROS evoked by TBHP in HepG2 cells. Finally, CWE pretreatments prevented the significant increase of glutathione peroxidase, catalase, glutathione reductase, and superoxide dismutase activities induced by TBHP. These results show that CWE has significant protective ability against a TBHP-induced oxidative insult and that the modulation of antioxidant enzymes by CWE may have an important antioxidant effect on TBHP-induced oxidative stress in HepG2 cells.

• Journal of Life Science
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• v.26 no.12
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• pp.1446-1457
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• 2016

Wetlands exhibit intermediate characteristics of both terrestrial and aquatic ecosystems, and the biodiversity is rich in these unique biological habitats. The symbiotic relationships between plants and fungi that inhabit these wetlands play an important role in natural resource management, biodiversity, and conservation. Accordingly, the mujechi, having academic value for the study of the natural environment, was investigated in terms of genetic diversity of endophytic fungi, which inhabit the roots of wild plants. The internal transcribed spacer (ITS) region was amplified to identify fungal strains. In total, 226 strains were isolated and categorized into three phyla, seven classes, 10 orders, 22 families, and 31 genera. In plants by endophytic fungi were classified in Isachne globosa (Ig) to 19 genera, Scirpus karuisawensis (Sk) to 11 genera, Utricularia racemosa (Ur) to 19 genera, and one incertae sedis, Eriocaulon decemflorum (Ed) to 11 genera. The fungal taxa was identified the genera Acephala (19.9%), Tolypocladium (16.3%), Neopestalotiopsis (11.5%), and Perenniporia (7.1%). The fungal group isolated from Isachne globosa (Ig) grew the largest number of isolated fungal strains. After comprehensive evaluation, the endophytic fungal group from Utricularia racemosa (Ur) ranked highest in diversity analyses. From the roots of wild plant in mujechi-neup, it confirmed the distribution and diversity of endophytic fungi. This study provides the basic data to understand fungal community structure in peat wetlands.

• Korean Journal of Food Science and Technology
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• v.27 no.2
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• pp.251-256
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• 1995

Sucrose is added to feed materials to alter the taste and texture of extruded products. Emulsifier can affect extrudate properties by forming complexes with amylose during extrusion-cooking. These ingredients may improve the cell structure and texture of cornmeal extrudates obtained by using $CO_{2}$ as a bubble forming agent. The objective of this study was to evaluate effects of sucrose (5% and 10%) and glyceryl monostearate (GMS) (0.75% and 1%) on properties of cornmeal extrudates produced with $CO_{2}$ at injection pressures from 1.04 to 2.07 MPa. Dough temperature increased and die pressure decreased when $CO_{2}$ was injected into barrel. The addition of sucrose to cornmeal resulted in decreasing dough temperature, specific mechanical energy (SME) input, and die pressure. SME input was not significantly influenced by GMS addition but die pressure was decreased when GMS was added. Extrudate density was decreased over observed $CO_{2}$ injection compared to GMS. WSI was significantly decreased with the addition of GMS. Paste viscosity was also decreased with addition of sucrose or GMS, but significant differences of paste viscosity among $CO_{2}$ injection pressures were not found. Stucture forming and texture of cornmeal extrudates by $CO_{2}$ injection was improved by adding GMS.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.589-592
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• 2008

This study was conducted to assess the durability of Chloride-inhibiting Low-Heat Cement while being subjected to freezing-thawing during winter seasons. Although durability varies slightly depending on the conditions of the jobsite, frost damage to concrete resulting from repeated freezing and thawing over the course of seasonal changes is the leading cause behind lowered concrete durability. in addition, concrete that has been subjected to freezing and thawing during the winter season develops a significant amount of expansive force at the core and begins to exhibit signs of damage, such as cracking, peeling, and detachment from the aggregate. Therefore, this study fabricated test specimens using a Chloride-inhibiting Low-Heat Cement(CLC) and the widely used blast furnace slag cement(BFS) and Ordinary Portland Cement(OPC) with water-to-cement ratios of 35%, 40% and 45%, respectively, to assess the durability index of the CLC as per resistance to freezing-thawing. The specimens were then tested using the KS F 2456 method (Testing method for resistance of concrete to rapid freezing and thawing) to measure the dynamic modulus of elasticity. The dynamic modulus of elasticity measurements were then used to derive the durability indices. By comparing the durability indices, it was confirmed that CLC, BFS, and OPC all had superior durability.

• Tuberculosis and Respiratory Diseases
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• v.61 no.1
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• pp.41-45
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• 2006

Background; Several clinical scoring systems are currently being used to predict the outcome of sepsis, but they all have certain limitations. Therefore, we sought to identify the proteomic biomarkers, with wsing proteomic tools, that differed according to the outcome of sepsis patients. Methods; Upon admission to the ICU, blood samples were obtained from the 16 patients with sepsis who were enrolled in this study. Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI -TOF MS) was used to identify the markers that could predict the outcome of sepsis. Results; We found six peaks, by using cation and anion chips, that statistically differed between those patients who died and those who survived. Conclusion; The biomarkers we found by using proteomic tools may help predict the prognosis and also plan the treatment of sepsis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.5B
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• pp.364-378
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• 2008

Data Envelopment Analysis(DEA) models can be used for performance evaluation on governmental funding projects for IT small and medium-sized enterprises associated with multiple-outputs/multiple-inputs. In order to enhance the accuracy of DEA efficiency scores, DEA models with exogenously fixed variables are required where the corporate competency is taken into account. Additionally, it is necessary to use multiple DEA basic as well as extended models so as to relax the restriction on the performance evaluation to relying on a single DEA model. In this study; 1)a DEA data structure is designed including exogenously fixed variables representing corporate asset, revenue and the number of employees at the point in time that the governmental funding project concerned is initiated; 2)DEA basic as well as extended models are established according to the DEA data structure presented abovementioned; and 3)a case study is illustrated with an empirical testbed dataset. As for the DEA basic models, CCR, BCC, Super-efficiency model are adopted. The DEA extended models are developed based on the models associated with noncontrollable and nondiscretionary variables. In the case study, it is explained a comparison of DEA models and also major numerical outcomes such as efficiency scores, ranks derived from each DEA model are integrated using Analytic Hierarchy Process(AHP) weights. Performance significance with DEA efficiency scores between technical categories are tested based not only on parametric but also nonparametric single-factor analysis of variance method.