• Title/Summary/Keyword: 요로 폐쇄

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Analysis of HLA in Patients with Obstructive Sleep Apnea Syndrome (폐쇄성 수면무호흡증후군 환자에서 사람백혈구항원 분석)

  • Lee, Sang Haak;Kim, Chi Hong;Ahn, Joong Hyun;Kang, Ji Ho;Kim, Kwan Hyoung;Song, Jeong Sup;Park, Sung Hak;Moon, Hwa Sik;Choi, Hee Baeg;Kim, Tai Gyu;Choi, Young Mee
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.3
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    • pp.298-305
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    • 2005
  • Background : Obstructive sleep apnea syndrome (OSAS) is believed to have multifactorial causes. The major risk factors for OSAS are obesity, narrowed upper airways, and abnormal cranial-facial structures. A genetic basis for OSAS has been also suggested by reports of families with many members affected. This study analyzed the HLA typing in patients with OSAS to determine the possible role of genetics in OSAS. Methods : Twenty-five Korean patients with OSAS (1 woman and 24 men; age range 30-66 years) were enrolled in this study. A diagnosis of OSAS was made using full-night polysomnography. The control group consisted of 200 healthy Korean people. Serologic typing of the HLA-A and B alleles was performed in all patients using a standard lymphocyte microcytotoxicity test. Analysis of the polymorphic second exons of the HLA-DRB1 gene was performed using a polymerase chain reaction-sequence specific oligonucleotide probe. Results : The allele frequency of HLA-A11 was significantly lower in patients with OSAS compared with the controls (p<0.05). The HLA-B allele frequencies in the patients and controls had a similar distribution. Analysis of the HLADRB1 gene polymorphisms showed an increased frequency of DRB1*09 in the OSA patients compared with the controls (p<0.05). When the analysis was performed after dividing the OSAS patients according to the severity of apnea, the allele frequency of HLA-DRB1*08 was significantly higher in the severe OSA patients (apnea index >45) than in the controls (p<0.05). Conclusion : This study revealed an association between OSAS and the HLA-A11 and DRB1*09 alleles as well as association between the disease severity and the HLA-DRB1*08 allele in Korean patients. These results suggest that genetics plays an important role in both the development and the disease severity of OSAS.

On the relationship between the phonetic realizations of the allophones of the Korean liquid /l/ and their prosodic status (한국에 유음 /l/의 변이음들의 음성적 실현과 운율적 위상과의 상관관계에 관하여)

  • 이숙향
    • The Journal of the Acoustical Society of Korea
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    • v.18 no.7
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    • pp.85-91
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    • 1999
  • The purpose of this study is to investigate phonetic realization of flap [r], one of the allophones of Korean /l/. Phonetic realization of a segment is affected by not only its neighboring segments but also its prosodic position in an utterance. This study examined how various prosodic positions affect the phonetic realization of [r]. Effects of the four prosodic positions on the phonetic realization of [r] were examined: utterance initial, Intonation Phrase initial, Accentual Phrase initial, and Accentual Medial positions. Word positional effect was also examined: word initial, medial, and final positions. Acoustic and statistical analyses showed that flap [r] was realized in a variety of phonetic forms: from sonorant(the most reduced form) to short stop(the least reduced form). It was shown that generally. word-initial position is stronger than word-medial position. It was also shown that in many cases, utterance-initial position and intonation-phrase-initial position are stronger than accentual-phrase-initial and accentual-phrase-medial positions. Sonorants were observed more often in the prosodically weaker portions. VOT duration was also shorter in accentual-phrase-initial and accentual-phrase-medial positions.

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Validation of Onen's Alternative Grading System for Congenital Hydronephrosis (선천성 수신증을 위한 Onen 등급 분류법의 임상적인 타당성)

  • Woo, Da Eun;Lim, Myung Hee;Kim, Myung Uk;Kim, Sae Yoon;Park, Yong Hoon
    • Childhood Kidney Diseases
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    • v.18 no.2
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    • pp.77-84
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    • 2014
  • Purpose: The purpose of this study was to compare the validity of Onen's alternative grading system (AGS) with that of the APDRP and SFU grading systems in patients with isolated and complicated congenital hydronephrosis. Methods: We retrospectively reviewed the medical records of 153 patients (204 renal units) diagnosed with congenital hydronephrosis between January 2002 and December 2011. We classified patients into 2 groups; isolated or complicated hydronephrosis. All renal units were graded according to anterior-posterior diameter of renal pelvis (APDRP), Society for Fetus Urology (SFU) and Onen's grading systems. We analyzed the prognosis of hydronephrosis, according to each grading system, at 2 years of age. Results: There were 152 renal units with isolated hydronephrosis and 52 renal units with complicated hydronephrosis. The isolated hydronephrosis group had a lower grade according to Onen's AGS, and showed more frequent spontaneous remission by 2 years of age. There was more frequent obstruction (P =0.000) and surgical treatment (P =0.000) of units with high-grade hydronephrosis according to Onen's AGS. In the complicated hydronephrosis group the frequencies of spontaneous remission (P =0.015) and renal dysfunction (P =0.013) were significantly higher than those in high-grade hydronephrosis, as indicated by Onen's AGS. There were no significant differences in clinical outcomes among the highest grade groups, according to the 3 systems, in either isolated or complicated hydronephrosis. Conclusion: Onen's AGS reflects the prognosis of hydronephrosis as well as other grading systems in those with isolated hydronephrosis. It was better predictor of renal dysfunction in those with complicated hydronephrosis. However, Onen's AGS was not superior to the other grading systems in terms of predicting prognosis, especially in high-grade hydronephrosis.

진주만과 인근해역의 동물성 부유생물의 군집구조

  • 마채우;천원석;김종춘;양윤선
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2000.05a
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    • pp.414-415
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    • 2000
  • 남해안의 중부에 위치한 삼천포 근해의 진주만과 자란만 등은 경남 사천군, 남해군 및 고성군에 접해있으며, 만 주변에는 여러 개의 섬이 산재해 있는 반폐쇄적인 만이다. 진주만의 안쪽에는 사천만이 위치해 있으며, 윗쪽은 남강의 하류 지역이다. 일반적으로 동물성 부유생물은 식물성 부유생물에 의해 합성된 유기에너지를 어류와 같은 더 높은 영양 단계로 전달하는 일차 소비자의 역할을 담당하며, 동물성 부유생물의 분포는 다양한 해양 생태 환경에 영향을 받는다. 동물성 부유생물은 피식과 종간 경쟁같은 생물적인 요인(Parsons et al., 1984)뿐만 아니라, 유영 능력이 미약하기 때문에 수온, 염분같은 물리적인 특성에 의해서도 영향을 받는다(Barlow, 1955; Lance, 1963). (중략)

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인터넷 지식공유에 영향을 미치는 요인 연구 : 사회적자본 이론과 자기표현욕구를 중심으로

  • Han, Jin-U;Yu, Cheol-U;Choe, Yeong-Chan
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2008.10b
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    • pp.170-177
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    • 2008
  • 기존의 지식공유에 관한 연구들은 KMS를 중심으로 연구를 진행하였다. 그러나 최근에는 폐쇄적 성격을 가진 KMS 뿐만 아니라 개방적인 성격의 인터넷 공간에서도 지식 공유활동이 활발하게 일어나고 있다. 네이버의 지식인, 포털 사이트들의 지식공유 공간들은 그 중요한 예가 될 것이다. 이런 인터넷 공간에서의 지식공유에 행동에 대한 연구는 미비하기 때문에 이에 대한 연구가 필요한다. 본 연구에서는 이런 상황들은 고찰하여 사회적자본 이론(Social Capital Theory)과 자기표현 개념을 중심으로, 인터넷 지식공유에 미치는 영향 요인들을 밝히고자 시도하였다. 실증분석을 위해서 구조모형을 제안하였으며 PLS를 사용하여 분석하였다. 결과적으로 사회적자본과 자기표현은 지식공유의도에 유의한 영향을 미치는 것으로 나타났다.

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IPTV의 새로운 가능성을 제시하는 SMART 스크린 기술

  • Sim, Jae-Cheol;Kim, Seon-Jung;Jo, Gi-Seong;Ryu, Won;Lee, Ho-Jin
    • Information and Communications Magazine
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    • v.27 no.5
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    • pp.16-23
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    • 2010
  • 방송 통신 융합의 대표적인 서비스인 IPTV가 상용으로 제공되고 있지만, IPTV는 아직 단순히 IP 망에서의 실시간 채널방송 및 VoD 서비스 범주를 크게 벗어나지 못하고 있다. 또한 IPTV사업자들이 Value Chain인 CPNT(Contents-Platform-Network-Terminal) 모든 요소에서 지배력을 가질수 있는 Walled Garden 형태의 폐쇄적 서비스 정책으로 새로운 신규 서비스 시장 성장의 장해요인으로 작용하고 있다. 반면 애플의 아이폰에서 보듯이 개인이 사용하는 단말은 점차 다양해지고 지능화되어 새로운 서비스의 가능성을 제시하고 있다. 정부가 10대 미래 서비스 전략의 하나로 추진하고 있는 SMART 스크린 서비스는 동일한 융합서비스(콘텐츠)를 원하는 시간과 장소에서 단말의 종류에 무관하게 PC, TV, 휴대 단말 등에서, 장소와 단말기간 이동 시에도 끊김 없이 서비스를 제공하는 기술이다. 본 고에서는 SMART 스크린 기술의 목표와 장애 요인, 그리고 이를 극복하기 위한 기술 개발 동향을 살펴본다.

A Case of Idiopathic Chylothorax and Chyluria (원인 미상으로 Chylothorax와 Chyluria가 병발한 1예)

  • Choi, Jung Min;Oh, Hyoung-Chul;Yi, Myung Zoon;Yun, Jae Pil;Kim, Jae Il;Kim, Woo Sung;Kim, Dong Soon;Kim, Won Dong;Shim, Tae Sun
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.4
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    • pp.377-380
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    • 2004
  • We report a rare case of idiopathic chylothorax and chyluria. A 31 year-old woman was referred to our hospital with a right-sided pleural effusion. Cream-colored pleural fluid and urine were confirmed as chylothorax and chyluria, respectively, by a lipoprotein electrophoresis. Even though she had previously underwent surgery for pelvic fibrosarcoma and experienced its recurrence, there has been no change of mass size and no evidence of thoracic duct or urinary tract obstruction as of the moment. Hence, idiopathic chylothorax and chyluira was diagnosed. Because she responded poorly to conservative treatment, thoracic duct ligation and pleurodesis were performend ; wherease chyluria was resolved spontaneously.

Reexpansion Pulmonary Edema (재팽창성 폐부종 3례 보고-)

  • Oh, Duck-Jin;Lee, Young;Lim, Seung-Pyeung;Yu, Jae-Hyeon
    • Journal of Chest Surgery
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    • v.29 no.5
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    • pp.581-584
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    • 1996
  • Reexpansion pulmonary edema is a rare complication of the treatment of lung collapse secondary to pneumothordx, pleural effusion, or atelectasis but occasionally life threatening. Generally, reexpansion pulmonary edema is believed to o cur only when a chronically collapsed lung is rapidly reexpanded by evacuation or large amounts of air or fluid. This complication is heralded by tachypnea, unilateral rales, and profuse expectoration of frothy secretion within several hours of reexpansion. Increased dur- ation of pneumothorax and the use o( suction are important factors in the generation of reexpansion pulmonary edema. We had experienced 3 cases of reexpansion pulmonary edema. In the two cases the pneumothorax had been present for several days, and, after insertion of a chest tube, pulmonary edema developed unilaterally but improved with supplemental oxygen. In the third case, massive pleural effusion was present. and, after insertion of a chest tube, pulmonary edema developed unilaterally, followed by cardiac arrest. He died of pulmonary edema inspire of resuscitation.

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A Case of the Bleomycin-Induced Bronchiolitis Obliterans Organizing Pneumonia (Bleomycin 투여 후 발생한 폐쇄세기관지기질화폐렴)

  • Hahn, Chang Hoon;Moon, Jin Wook;Chang, Jae Hyun;Choi, Byoung Wook;Shin, Dong Whan;Kim, Se Kyu;Chang, Joon;Kim, Sung Kyu;Kim, Young Sam
    • Tuberculosis and Respiratory Diseases
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    • v.55 no.3
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    • pp.311-316
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    • 2003
  • A 34-year-old man was admitted to our hospital due to fever and cough. He received the combination anti-cancer chemotherapy for testicular tumor, including bleomycin. The chest X-ray showed consolidation and ground glass opacity on the right upper lobe and subpleural areas of other lobes. This condition was initially misdiagnosed as a pneuomonia, but consolidation did not disappear after antibiotics treatment. We performed transbronchial lung biopsy and bleomycin induced pulmonary toxicity was confirmed. The bleomycin induced lung injury is the most common chemotherapeutically induced pulmonary disease. Bleomycin induced Bronchiolitis Obliterans Organizing Pneumonia(BOOP) is less common than interstitial pneumonitis and responds well to corticosteroid treatment.

Burnout Process Model of Social Workers: Analysis of the Paths from the Job-related Stressors, Job-stress and Professional Self-efficacy to Burnout (사회복지사의 소진과정(Burnout Process) 모델 - 직업관련 스트레스 요인, 직무스트레스와 전문직효능성에 의한 소진 경로분석 -)

  • Lee, Myung-Shin
    • Korean Journal of Social Welfare
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    • v.56 no.4
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    • pp.5-34
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    • 2004
  • This study aims to find out the determinants of burnout in order to better understand the burnout process among social workers. For this purpose, a hypothetical model which explains the relationships among 8 job-related stressors (role ambiguity, role overload, difficulties in solving problems of clients, conflict with the clients, lack of support from the supervisor, closed communication pattern, bureaucracy, and lack of accountability), 4 mediators (job-stress, professional role performance, abiding by the agency policy and partiality in service delivery), and 4 dimensions of burnout (physical exhaustion, psychological exhaustion, depersonalization and personal accomplishment) was developed. Using the data collected from 207 social workers, the hypothetical model was tested. For data analysis, a path analysis was used, and the best-fitting model was found(df=66, $x^2$=63.250, GFI=0.962, CFI=1.00). As a result of this study, the following results were found. Burnout among social workers was increased by the 6 job-related stressors(role ambiguity, role overload, difficulties in solving problems of clients, conflict with the clients, lack of support from the supervisor, closed communication pattern). Job-stress, the mediating variable of the emotional path to burnout, increased professional role performance and the abiding by agency policy, and finally increased burnout. On the other hand, professional self-efficacy (which consists of professional role performance, abiding by agency policy and partiality in service delivery), the mediationg variable of the cognitive path to burnout, reduced burnout when the professional role performance was high, and abiding by agency policy and partiality in service delivery were low.

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