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Measurement of proptosis for korean young people with the Hertel exophthalmometer (Hertel 안구돌출계에 의한 한국인 청년의 안구 돌출도 측정)

  • Kim, Sang-Moon
    • Journal of Korean Ophthalmic Optics Society
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    • v.6 no.2
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    • pp.129-137
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    • 2001
  • The proptosis of 100 healthy Korean young people was estimated. The average protrusion measured with Hertel exophthalmometer was $14.6{\pm}0.51mm$ and $13.7{\pm}0.42mm$ in the right eye, $14.2{\pm}0.46mm$ and $13.6{\pm}0.42mm$ in the left eye by two observers(A, B), and so right eye was higher than left eye. There is no significant difference of proptosis between two eyes and among the visual acuity in the man and woman. The average coefficient of variation among five measurements by two observers was 3.53% and 3.10% in the right eye, 3.32% and 3.11% in the left eye. The mean base line by two observers was $106.7{\pm}1.13mm$ and $108.4{\pm}1.08mm$ in the man, $103.4{\pm}1.23mm$ and $104.8{\pm}1.02mm$ in the woman, respectively.

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Effect of Snake Venom on Cancer Growth through Induction of Apoptosis via Down Regulation of NF-${\kappa}B$ and STAT3 in the PA-1, Ovarian Cancer Cells (사독(蛇毒)이 난소암세포에 있어서 NF-${\kappa}B$와 STAT3의 활성억제와 관련된 세포자멸사유도를 통한 암세포 성장에 미치는 영향)

  • Lee, Byung-Choon;Song, Ho-Sueb
    • Journal of Acupuncture Research
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    • v.29 no.1
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    • pp.37-45
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    • 2012
  • 목적 : 최근 NF-${\kappa}B$와 STAT3의 활성억제와 관련된 항암제 연구가 주목받고 있으며, 본 연구는 사독(蛇毒)이 세포자멸사 관련 단백질의 발현 조절을 통하여 세포자멸사를 유도하고, NF-${\kappa}B$와 STAT3의 활성억제를 유도하여 난소암 PA-1 세포의 성장을 억제하는지를 확인하고, 해당 기전을 살펴보고자 하였다. 방법 : 사독을 처리한 후 난소암 PA-1 세포의 세포자멸사의 관찰에는 DAPI, TUNEL staining assay를 시행하였고, 세포자멸사 조절단백질 및 NF-${\kappa}B$, STAT3의 활성 변동 관찰에는 western blot analysis를 시행하였다. 결과 : 1. 사독을 처리한 후 난소암 PA-1 세포에서 세포자멸사가 유도되어 암세포성장이 억제되었다. 2. 사독을 처리한 후 세포자멸사 관련 단백질 중 세포자멸사 촉진 단백질인 cleaved caspase-3, Bax의 발현은 증가되었고, 세포자멸사 억제 단백질인 Bcl-2의 발현은 감소되었다. 3. 사독을 처리한 후 난소암 PA-1 세포의 NF-${\kappa}B$와 STAT3 발현은 감소되었고, 각각의 길항제인 salicylic acid와 stattic 처리 후 NF-${\kappa}B$와 STAT3 발현은 더욱 감소되었다. 결론 : 사독은 난소암 세포의 세포자멸사 유발과, NF-${\kappa}B$와 STAT3의 활성억제를 통해 치료 효율이 높고, 내성이 적은 난소암 치료제의 개발에 도움이 될 것으로 기대된다.

Absorption, Translocation and Metabolism of Bensulfuron in Rice and Cyperus serotinus Rottb. (수도(水稻)와 너도방동사니에서 Bensulfuron의 흡수(吸收), 이행(移行) 및 대사(代謝))

  • Kwon, C.S.;Pyon, J.Y.
    • Korean Journal of Weed Science
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    • v.13 no.2
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    • pp.75-80
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    • 1993
  • Root absorption, translocation and metabolism studies of $^{14}C$-bensulfuron in rice and Cyperus serotinus Rottb. were conducted to determine their selective mode of action. Rice absorbed a greater amount of bensulfron than Cyperus serotinus. The translocation rates of bensulfuron from roots into shoots were much faster in Cyperus serotinus than rice plants. The metabolic rate of bensulfuron was very fast in rice plants, but slow in Cyperus serotinus and therefore, the amount of parent bensulfuron remained in the shoots after 12 hours absorption was greater in Cyperus serotinus than rice. In conclusion, this studies indicated that Cyperus serotinus was susceptible to bensulfuron because of the slower metabolic rate and fast translocation rate, but tolerance of rice might be caused by faster metabolic rate in plants.

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Synthesis of Copolyimide Containing 5,15-Bis(mesityl)-10,20-bis(4-amino)porphyrin (5,15-Bis(mesityl)-10,20-bis(4-amino)porphyrin을 포함하는 Copolyimide의 합성)

  • Kim, Hooi-Sung;Lee, Min-Ho;Kim, Chun-Ho;Kim, Mi-Ra;Lee, Jin-Kook
    • Applied Chemistry for Engineering
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    • v.10 no.6
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    • pp.828-831
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    • 1999
  • 5,15-Bis(mesityl)-10,20-bis(4-amino)porphyrin was synthesized with meso-(mesityl)dipyrromethane and 4-nitrobenzaldehyde. It was characterized with $^1H$-NMR spectroscopy, UV spectrophotometer, and GC-MASS. In UV spectrum, Soret-band(438 nm) and Q-bands(526, 572, 611 nm) were confirmed. In NMR spectrum, the characteristic peak of porphyrin was detected at -2.65 ppm. Copolyimide containing porphyrin structure was synthesized with mesityl-$TPP(NH_2)$, 3,3',4,4'-benzophenonetetracarboxylic dianhydride(BTDA) and 2,2-bis(4-(4-aminophenoxy)phenyl) hexafluoropropane(BAPHF) and characterized with UV and FT-IR spectrophotometer. The $T_g$ and $T_m$ of the synthesized copolyimide were 220.7 and $369.2^{\circ}C$, respectively.

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Effect of Antibiotics on Phospholipid Biosynthesis and Fatty Acid Composition in Chlorella ellipsoidea Chloroplasts (Chlorella ellipsoidea 엽록체의 인지질 생합성 및 지방산 조성에 미치는 항생제의 효과)

  • 조수열
    • Journal of Plant Biology
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    • v.35 no.1
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    • pp.25-36
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    • 1992
  • The effects of amphotericin B ($150\;\mu\textrm{g}/ml$) and cycloheximide ($10\;\mu\textrm{g}/ml$) on the biosynthesis of phospholipid and the composition of fatty acids in chloroplasts isolated from ChZorella were analyzed. The contents of the total lipid and phospholipid (PC, PE, PI) in treatment with antibiotics were lower compared with the control. In the whole cell system, the major fatty acids utilized for biosynthesis of phospholipid were palmitic acid (31.96%) and linoleic acid (16.96%) in control while those were palmitic acid (36.15%) and linolenic acid (16.71%) in treatment with amphotericin B. And in treatment with cycloheximide, palmitic acid (31.90%) and stearic acid (15.32%) were used in phospholipid formation. The major fatty acids in chloroplasts were analyzed as to be palmitic acid and linolenic acid in control (33.75%, 18.90%) and in treatment with amphotericin B (36.75%, 9.46%). However, it was shown that the major fatty acids in chloroplasts treated with cycloheximide were palmitic acid (28.01%) and oleic acid (19.27%).9.27%).

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A Study on the International Research Trends in Electronic Records Management: InterPARES 3 and ITrust Achievements (전자기록관리에 대한 국제 연구 동향 분석 - InterPARES 3와 ITrust 성과물을 중심으로 -)

  • Park, Ok nam;Park, Heejin
    • Journal of Korean Society of Archives and Records Management
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    • v.16 no.1
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    • pp.89-120
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    • 2016
  • This study aims to understand the concept and changes of the records management of InterPARES based on the analysis of background, main research interests, and major achievements of IP3 and ITrust. To this end, this study conducted a content analysis of IP3 and ITrust to drive main keywords. This study also utilized word clouds from IP project titles. In addition, a comparative analysis of IP3 and ITrust was conducted based on the environment, scope, core research areas, keywords, objectives, and record management life cycle perspectives. The research identified that InterPARES research was widely expanding the content and subject areas of the study: 1) to apply across the life cycle, as well as long-term preservation; 2) to focus on the concept of trust as well as the concept of authenticity; and 3) to include the concept of the Internet, digital forensics, and the open government along with electronic records.

Plant Damages and Yields of the Different Rice Cultivars to Brown Planthopper (Nilaparvata lugens S.) in Fields (벼멸구에 의한 벼품종(品種)의 피해(被害)와 수량(收量))

  • Kim, Y.H.;Lee, J.O.;Park, H.C.;Kim, M.S.
    • Korean journal of applied entomology
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    • v.24 no.2 s.63
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    • pp.79-83
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    • 1985
  • Plant damages and yields of the different rice cultivars to brown planthopper (BPR), Nilaparvata lugens S., were observed for the evaluation of varietal resistance in paddy fields. Twenty nine Korean cultivas were transplanted in paddy fields with three plots of no insecticide, no insecticide and fungicide, and no fungicide at Haenam, southern coastal area in 1983. Among 6 varieties with BPR resistant genes, Samgang, Gaya, Hangangchal, and Cheongcheong showed very low populations of BPR and no damages on all treatments. Milyang 30 and Wonpung among them had considerable populations of BPR. Seokwang and 23 others showed high populations and serious damages. Yield increasea(%) with insecticides were low on Gaya(12%), Samgang(29%) and Hangangchal(35%), but very high on Bongkwang(260%), Palgueum(223%), Songjeon(200%), and Guanauk(200%).

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Analysis of Expression Patterns of Thymosin β4 and CD133 in Normal Stomach (정상 위 조직에서 thymosin β4와 CD133의 발현 양상 분석)

  • Ock, Mee Sun;Cha, Hee-Jae
    • Journal of Life Science
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    • v.22 no.10
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    • pp.1415-1419
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    • 2012
  • Thymosin ${\beta}4$ ($T{\beta}4$) has been reported to be overexpressed in CD133-positive colorectal cancer stem cells. We analyzed the relationship between $T{\beta}4$ and CD133-positive stem cells in normal stomach by examining the expression patterns of $T{\beta}4$ and CD133 in normal stomach tissues by immunohistochemical staining; co-localization of $T{\beta}4$ and CD133 was studied by immunofluorescence and confocal laser-scanning microscopy. Both $T{\beta}4$ and CD133 were expressed in stomach glands and showed similar expression patterns. Immunofluorescence staining of $T{\beta}4$ and CD133 showed that the expression of $T{\beta}4$ and CD133 was co-localized. In summary, both $T{\beta}4$ and CD133 were expressed in glands of normal stomachs and expression patterns were co-localized. These data suggest that $T{\beta}4$ expression is strongly related to CD133 expression.

Calcium silicate의 생성반응에 미치는 $\SO_3$의 영향

  • 박병철
    • Cement
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    • s.92
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    • pp.41-54
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    • 1983
  • Calcium Silicate의 생성 및 분해에 미치는 $K_2SO_4$$MgSO_4$의 영향을 비교 검토하였으며 Calcium Silicate의 생성을 최대로 하는 $SO_3$, MgO와 $K_2O$의 최적비를 반응표면분석기법으로 조사하였다. $K_2SO_4$의 혼합비 증감에 따라 $C_3S$의 생성촉진에 미치는 영향은 없었다. $C_3S$의 조합원료에 $CaSO_4$를 4.0wt$\%$이상 첨가시 $CaSO_4$$C_2S$주위에 Sulphate reaction rim을 형성함으로써 $C_2S$와 CaO의 반응을 방해해 $C_3S$의 생성을 억제하였으나 적당량의 MgO가 첨가되면 $CaSO_4$가 4.0wt$/%$이상이라도 $C_3S$의 생성은 억제되지 않았다. $C_3S$의 생성을 최대로 하기 위한 $SO_3$, MgO와 $K_2O$의 최적비를 반응표면분석기법을 이용하여 다음과 같은 결론을 얻었다. 1. $K_2SO_4$$K_2O$에 비해 소결에 미치는 영향이 적으므로 크링카에 고용되고 남은 $K_2O$는 전량 $K_2SO_4$로 전환시켜야한다. 2. $SO_3$$K_2O$의 최적비율은 1.5이다. 3. $CaSO_4$와 MgO의 최적비율을 유지하기 위해서는 $CaSO_4$중의 wt$\%SO_3$=0.7의 수준으로 Sulphate의 함량을 조절하여야 한다. 4. $SO_3$와 결합하고 남은 $K_2O$가 0wt$\%$인 경우는 $K_2SO_4$=2.3wt$\%$, MgO=1.5wt$\%$일때 $C_3S$의 생성이 최대로 된다. 5. $SO_3$와 결합하고 남은 $K_2O$가 2.0wt$\%$인 경우는 $K_2$$SO_4$=4.5wt$\%$, MgO=3.0wt$\%$일때 $C_3S$의 생성이 최대로 된다.

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Effects of the Post-annealing of Insulator on the Electrical Properties of Metal/Ferroelectric/Insulator/Semiconductor Structure (절연막이 후 열처리가 Metal/Ferroelectric/Insulator/Semiconductor 구조의 전기적 특성에 미치는 영향)

  • 원동진;왕채현;최두진
    • Journal of the Korean Ceramic Society
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    • v.37 no.11
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    • pp.1051-1057
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    • 2000
  • TiO$_2$와 CeO$_2$박막을 Si 위에 증착한 후 MOCVD법에 의해 PbTiO$_3$박막을 증착하여 MFIS 구조를 형성하였다. 절연층의 후열처리가 절연층 및 MFIS 구조의 전기적 특성에 미치는 영향을 관찰하기 위해 산소분위기와 $600^{\circ}C$~90$0^{\circ}C$의 온도범위에서 후 열처리를 행하였고, C-V 특성 및 누설전류 특성을 분석하였다. CeO$_2$와 TiO$_2$박막의 유전상수는 증착 직후 6.9와 15였으며, 90$0^{\circ}C$ 열처리를 행한 후 약 4.9와 8.8로 감소하였다. 누설전류밀도 역시 증착 직후 각각 7$\times$$10^{-5}$ A/$ extrm{cm}^2$와 2.5$\times$$10^{-5}$ A/$\textrm{cm}^2$에서 90$0^{\circ}C$ 열처리를 거친 후에 약 4$\times$$10^{-8}$ A/$\textrm{cm}^2$와 4$\times$$10^{-9}$ A/$\textrm{cm}^2$로 감소하였다. Ellipsometry 시뮬레이션을 통해 계산된 계면층의 두께는 90$0^{\circ}C$에서 약 115$\AA$(CeO$_2$) 및 140$\AA$(TiO$_2$)까지 증가하였다. 계면층은 MFIS 구조에서 강유전층에 인가되는 전계를 감소시켜 항전계를 증가시켰고, charge injection을 방지하여 Al/PbTiO$_3$/CeO$_2$(90$0^{\circ}C$, $O_2$)/Si 구조의 경우 $\pm$2 V~$\pm$10 V의 측정범위에서 memory window가 계속 증가하는 것을 보여주었다.

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