• Title/Summary/Keyword: 영역-상보성

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Three Dimensional Visualization of Contact Region for a Protein Complex (단백질 복합체를 위한 접촉 영역의 3차원 가시화)

  • Kang, Beom Sik;Kim, Ku-Jin;Kim, Yukyeong
    • KIPS Transactions on Software and Data Engineering
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    • v.2 no.12
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    • pp.899-902
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    • 2013
  • In this paper, we present a method to visualize the contact region between two molecules in a protein complex in a threedimensional space. The contact region of two molecules shows compatibility in geometric aspects. Usually, the computation of the area of contact region has been used to show the strength of compatibility. The numerical value and simple drawing of contact region would be useful for comparing the relative strength of different contacts, but it is not appropriate for analysing the geometric characteristics of the contact region. In this paper, we present a method to show the compatibility between two molecules by visualizing the distance information between them.

A Comparative Study on the Institutional Complementarities in Coordination of the sphere of Distribution and Production: Focus on the Determinants of Income Inequality (분배조정과 생산조정의 제도적 상보성에 관한 비교사회정책연구: 소득 불평등에 미친 영향을 중심으로)

  • Baek, Seung-Ho
    • Korean Journal of Social Welfare
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    • v.57 no.4
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    • pp.91-118
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    • 2005
  • This paper examines the impact of the institutional complementarity between welfare regimes and production regimes on income inequality. Using comparative welfare data by various sources for 14 OECD nations from 1980 to 1997, this paper attempts to answer two questions. First, is there a institutional complementary in regulatory process between distribution and production? Second, if it is correct, what kind of causal structure do we predict? Panel Corrected Standard Errors(PCSE) model, a data analysis method in pooled cross-sectional time-series, is employed to examine the interaction effects between the two variables: coordination in the sphere of distribution; coordination in the sphere of production The evidence suggest that there are powerful interaction effects between distributive coordination and production coordination and that the institutional complementary has effects on income inequality. First, the income inequality effect of coordination in the sphere of distribution becomes less positive(more negative) as coordination in the sphere of production increases. Second, the income inequality effect of coordination in the sphere of production becomes less positive(more negative) as coordination in the sphere of distribution increases.

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The comparison of domain in creativity among performance groups (창의성의 영역성에 대한 수행집단간의 비교연구)

  • Lee, Jeong-Kyu
    • Journal of Gifted/Talented Education
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    • v.13 no.4
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    • pp.119-140
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    • 2003
  • The purpose of this study is to examine the dispute over creativity domain at schools in Korea. In other words, this study is to examine the creativity domain among all subjects, a group of high level performance, and a group of low level performance in creativity. Based on ability-differentiation hypothesis, correlation among 4 domains, correlation between divergent thinking variables of domain-generality and 4 domains of domain-speciality, and multiple linear regression have been computed. The results are opposed to the hypothesis. The group of low level performance is related to domain-speciality. The group of high level performance, however, has relationships neither domain-generality nor domain-speciality. Instead of differentiation between domain-generality and domain-speciality, the results support the domain-complementarity.

Visualization of Geometric Features in the Contact Region of Proteins (단백질 접촉 영역의 기하학적 특성 가시화)

  • Kim, Ku-Jin
    • KIPS Transactions on Software and Data Engineering
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    • v.8 no.10
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    • pp.421-426
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    • 2019
  • In this paper, we propose a method to visualize the geometric features of the contact region between proteins in a protein complex. When proteins or ligands are represented as curved surfaces with irregularities, the property that the two surfaces contact each other without intersections is called shape compatibility. Protein-Protein or Protein-Ligand docking researches have shown that shape complementarity, chemical properties, and entropy play an important role in finding contact regions. Usually, after finding a region with high shape complementarity, we can predict the contact region by using residual polarity and hydrophobicity of amino acids belonging to this region. In the research for predicting the contact region, it is necessary to investigate the geometrical features of the contact region in known protein complexes. For this purpose, it is essential to visualize the geometric features of the molecular surface. In this paper, we propose a method to find the contact region, and visualize the geometric features of it as normal vectors and mean curvatures of the protein complex.

Transmissivity property of condition of melting temperature and added quantity of copper of phosphate glass for ir filter (Ir-filter용 인산계 유리의 용융조건과 Cu 첨가량에 따른 투과율 특성)

  • Kim, Seong-Il;Hwang, Jong-Hee;Lim, Tae-Young;Kim, Jin-Ho;Choi, Duck-Kyun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2009.06a
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    • pp.337-337
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    • 2009
  • 가시광선영역에서 매우 균일한 높은 투과성뿐만 아니라 근적외선영역에서 가파른 홉수성 엣지와 함께 낮은 투과율을 제공하는 산화구리(II)를 함유하는 포스페이트 유리는 컬러 비디오 카메라의 컬러 보정 필터, 발광 컬러 디스플레이용 보호판(sheild), 모노크로메이터의 미광 필터, 플라스틱 복합재 필터의 무기 성분 및 CCD(전하 결합 소자) 및 CMOS(상보성 금속 산화물 반도체) 카메라 및 검출기 분야용 필터 유리로서 사용된다. 용융온도 및 산화구리(II) 첨가량에 따른 투과율을 측정하기 위해 포스페이트 유리 시료를 $1100\sim1500^{\circ}C$ 용융한 후 $400^{\circ}C$에서 2시간 동안 어닐링 공정을 거쳐 제조하였다. 제조된 시료는 두께 0.3mm로 폴리싱하여 자외선-적외선 분광 광도기를 이용하여 광학적 특성을 측정하였다. 본 실험을 통하여 용융온도에 따라 가시광선영역 및 근적외선영역에서의 투과율 거동을 비교한 결과 $1100\sim1200^{\circ}C$에서의 우수한 투과율 특성을 나타냈다. 용융온도가 내려감에 따른 가시광선영역 (400~600nm)에서 높은 투과율 및 근적외선영역 (750~1100nm)에서 낮은 투과율과 가파른 흡수성 엣지를 나타냈다.

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Transcriptional Regulation of the Murine Dopamine Receptor Regulating Factor (DRRF) Gene (생쥐 도파민 수용쳬 조절인자 (DRRF) 유전자의 전사조절)

  • Kim Ok Soo;Lee Young-Choon;Lee Sang-Hyeon
    • Journal of Life Science
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    • v.15 no.1 s.68
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    • pp.55-60
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    • 2005
  • The murine dopamine receptor regulating factor (DRRF) gene is transcribed from a TATA-less promoter that has several putative Sp1 binding sites. The present investigation identifies functional transcription factors that modulate the expression of this gene, In the $D_2-expressing$ NB41A3 cells, Spl potently activates transcription from the DRRF promoter in pCAT-DRRF-1153/+17, but DRRF effectively inhibits it. Deletion of the 31 bp fragment between -1153 and -1122 decreased transcription down to about $60\%$. This fragment contains a functional API binding site. In addition, deletion of the 129 bp region between -901 and -772 further decreased transcription. The latter region has a functional AP2 binding site. Using a DRRF_AP1 (bases -1153 to -1121) probe, a specific retarded band was observed, and the unlabeled AP1 consensus competitor could effectively compete away this retarded band. In addition, using a DRRF_AP2 (bases -873 to -846), a specific retarded band was observed, and the unlabeled AP2 consensus competitor could effectively compete away this retarded band. The present observations suggest that Spl and DRRF regulate the DRRF promoter and that both API and AP2 also modulate this gene.

The Relation between Regional Identity and National Identity in Regional Learning - A Case Study of Regional Textbook in Jeju Province - (지역학습에 있어서 민족정체성과 지역정체성의 관계 - 제주 지역교과서 분석은 사례로 -)

  • 남호엽;김일기
    • Journal of the Korean Geographical Society
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    • v.36 no.4
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    • pp.483-494
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    • 2001
  • The purpose of this study is to analyze the relation between regional identity and national identity in a regional textbook in Korea. In geography education, regional textbooks are curriculum materials which represent regional identity based on territorial difference from other regions. In local curriculum level, the harmony between national unity and regional identity is to be pursued as educational objective. However, this harmony appears to be distorted in the school textbook in Je-Ju Province, a case region. For example, Confucian cultural landscapes are represented as otherness in regional discourses, but togetherness in the regional textbook. Also, the regional textbook implies that the boundary of external territorialization is mainly not regions but nations, and it seems to intend that leasers get a sense of place towards their region as periphery of nation. Therefore, we argue that regional identity, which must be stressed in a regional textbook, is marginalized in a case region.

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MicroRNA Target Prediction using a Support Vector Machine and Position based Features (SVM과 위치 기반의 자질을 이용한 MicroRNA 목표 유전자 예측)

  • Kim Sung-Kyu;Zhang Byoung-Tak
    • Proceedings of the Korean Information Science Society Conference
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    • 2005.07b
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    • pp.286-288
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    • 2005
  • MicroRNA (miRNA)는 작은 크기의 RNA분자로서 동식물의 유전자 발현 과점을 직접적으로 조절하는 인자로 알려져 있다. MiRNA는 보통 목표 유전자의 3'-UTR 영역에 상보성을 갖고 결합함으로써 작용하며 특히 miRNA의 5'부분의 8 nt 정도가 seed로서 중요하다고 알려져 있다. 반면 최근의 연구에 따르면 seed 부분의 서열의 조성 및 양상이 변화함에 따라 특이도가 결정됨을 알 수 있지만 기존의 컴퓨터를 이용한 miRNA 목표 유전자 예측 방법들은 이러한 정보를 활용하지 못한다. 본 논문에서는 열역학적인 수치와 서열의 조성뿐 아니라 miRNA:mRNA pair의 위치에 기반한 정보들을 학습에 자질로서 포함하여 목표 유전자를 예측한다. 그 결과는 위치 기반 자질이 학습 성능 향상에 중요하게 기여함을 보여준다.

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Speech-to-MIDI Conversion with Autocorrelation (자기상관을 이용한 음성 신호의 MIDI 변환)

  • 박상보;황인준
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10c
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    • pp.439-441
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    • 2004
  • 효율적인 멀티미디어 검색의 필요성이 증대됨에 따라 내용기반 멀티미디어의 검색에 대한 다양한 기법들이 소개되고 있다. 그 중에서 친숙한 멜로디를 가지고 사용자가 직접 마이크를 통해 생성한 음성 질의에 대한 분석에 대해 다루고자 한다. 음성 질의에 사용되는 음성 데이터를 분석함으로써 검색에 이용하는 것이다. 음성데이터를 분석하기 위한 방법으로 시간영역에서 가장 많이 쓰이는 기법 중의 하나인 자기상관함수를 사용한다. 자기상관 함수를 이용하여 특정구간에서 발생하는 일정한 주기 즉 기본주기를 검출할 수 있다. 자기상관함수에 의해 분석된 결과를 가지고, 음의 높낮이를 구하기 위한 기본주파수 검출 알고리즘과 음의 길이, 음의 세기를 결정하기 위한 방법을 제안한다.

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Cloning and Transcription Analysis of Sporulation Gene (spo5) in Schizosaccharomyces pombe (Schizosaccharomyces bombe 포자형성 유전자(spo5)의 Cloning 및 전사조절)

  • 김동주
    • The Korean Journal of Food And Nutrition
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    • v.15 no.2
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    • pp.112-118
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    • 2002
  • Sporulation in the fission yeast Schizosaccharomyces pombe has been regarded as an important model of cellular development and differentiation. S. pombe cells proliferate by mitosis and binary fission on growth medium. Deprivation of nutrients especially nitrogen sources, causes the cessation of mitosis and initiates sexual reproduction by matting between two sexually compatible cell types. Meiosis is then followed in a diploid cell in the absence of nitrogen source. DNA fragment complemented with the mutations of sporulation gene was isolated from the S. pombe gene library constructed in the vector, pDB 248' and designated as pDB(spo5)1. We futher analyzed six recombinant plasmids, pDB(spo5)2, pDB(spo5)3, pDB(spo5)4, pDB(spo5)5, pDB (spo5)6, pDB(spo5)7 and found each of these plasmids is able to rescue the spo5-2, spo5-3, spo5-4, spo5-5, spo5-6, spo5-7 mutations, respectively. Mapping of the integrated plasmid into the homologous site of the S. pombe chromosomes demonstrated that pDB(spo5)1, and pDB(spu5)Rl contained the spo5 gene. Transcripts of spo5 gene were analyzed by Northern hybridization. Two transcripts of 3.2 kb and 2.5kb were detected with 5kb Hind Ⅲ fragment containing a part of the spo5 gene as a probe. The small mRNA(2.5kb) appeared only when a wild-type strain was cultured in the absence of nitrogen source in which condition the large mRNA (3.2kb) was produced constitutively. Appearance of a 2.5kb spo5-mRNA depends upon the function of the meil, mei2 and mei3 genes.