• 제목/요약/키워드: 연세대학교

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비소 오염 토양의 복원을 위한 자철석과 바닥재 활용 (Remediation of As-contaminated Soil Using Magnetite and Bottom Ash)

  • 오세진;강민우;이종철;이훈호;노현석;전유권;김동진;이상수
    • 한국환경농학회지
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    • 제41권4호
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    • pp.223-229
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    • 2022
  • BACKGROUND: Mining activities, smelter discharges, and sludges are the major sources of heavy metal contamination to soils. The objective of this study was to determine the efficiency of magnetite and bottom ash derived from coal ash in remediating As-contaminated soil. METHODS AND RESULTS: An incubation experiment was conducted for 10 weeks. Magnetite and bottom ash at different rates and ratios were applied to each plastic bottle repacked with 1,000 g of dried As-contaminated soil. After 3-weeks of incubation, the concentrations of available As were measured by using Mehlich-3, SBET, and sequential extraction methods. All of the subjected soil amendments resulted in significant decreases in available As concentration compared to the controls. The addition of magnetite at the highest rate was the best to stabilize As in the soils; however, the values of As concentration varied with the extraction methods. CONCLUSION(S): To ensure the stabilization accuracy of heavy metals in soil, both single and sequential extractions are recommended. The magnetite derived from fly coal ash can also be applicable as a heavy metal stabilizer for the As-contaminated soil.

단결정 PbTe 단일 나노선의 열전도도 (Thermal Conductivity in Individual Single-Crystalline PbTe Nanowires)

  • 노종욱;장소영;강주훈;이승현;노진서;박정희;이우영
    • 대한금속재료학회지
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    • 제48권2호
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    • pp.175-179
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    • 2010
  • We investigated the thermal conductivity of individual single-crystalline PbTe nanowires grown by chemical vapor transport method. Suspended MEMS was utilized to precisely measure the thermal conductivity of an individual nanowire. The thermal conductivity of a PbTe nanowire with diameter of 292 nm was measured to be $1.8W/m{\cdot}K$ at 300 K, which is about two thirds of that of bulk PbTe. This result indicates that the thermal conduction through a PbTe nanowire is effectively suppressed by the enhanced phonon boundary scattering. As the diameter of a PbTe nanowire decreases, the corresponding thermal conductivity linearly decreases.

한국 지역 간 보건의료수준의 상대적 위치 비교 연구: Position Value for Relative Comparison Index를 활용하여 (A Study on Regional Differences in Healthcare in Korea: Using Position Value for Relative Comparison Index)

  • 윤흰뫼;윤초아;강수현;권준현;이현지;박은철;장성인
    • 보건행정학회지
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    • 제31권4호
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    • pp.491-507
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    • 2021
  • Background: This study aims to measure regional healthcare differences in Korea, and define relatively underserved areas. Methods: We employed position value for relative comparison index (PARC) to measure the healthcare status of 250 areas using 137 indicators in five following domains: healthcare demand, supply, accessibility, service utilization, and outcome. We performed a sensitivity analysis using t-SNE (t-distributed stochastic neighboring embedding). Results: Based on PARC values, 83 areas were defined as relatively underserved areas, 49 of which were categorized as moderate and 34 as severe. The provincial regions with the most underserved areas were Gyeongbuk (16 areas), Gangwon (13), Jeonnam (13), and Gyeongnam (12). Conclusion: This study suggests a relative comparison approach to define relatively underserved areas in healthcare. Further studies incorporating various perspectives and methods are required for policy implications.

간호학과와 타 보건의료관련 학과 학생들의 전문직 간 학습 준비도 차이 (Differences between Perceived Readiness for Interprofessional Learning in Nursing and Other Health-related Students)

  • 이현경;김인숙;이태화;김광숙;조은희;이경희;김정희
    • 한국간호교육학회지
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    • 제25권3호
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    • pp.312-320
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    • 2019
  • Purpose: The purpose of this study was to investigate the level of perceived readiness for interprofessional learning and its differences between nursing and other health-related students. Methods: A web-based survey was conducted from April 25 to June 30, 2017 in one university in Korea. A total of 325 undergraduate nursing students and other health-related disciplines completed the structured questionnaire consisting of Readiness for Interprofessional Learning Scale and general characteristics. Data were analyzed by descriptive statistics, t-test, ANOVA, and multiple linear regression. Results: The scores of readiness for interprofessional learning in nursing students were significantly higher than those in other health-related students (t=3.50, p=.001). Nursing students had higher collaboration, professional identity, and roles and responsibilities than other health-related students. The class experiences with other major students was a significant factor related to the readiness for interprofessional learning both in nursing (p=.001) and other health-related students (p=.001). Conclusion: The findings suggest that nursing educators consider the different level of readiness for interprofessional learning between nursing and other health-related students while integrating interprofessional education into nursing education curricula.

아세트아미노펜 중독 환자에서 간독성 발생 예측인자들의 유용성 (Usefulness of Predictors for Hepatotoxicity in Acetaminophen Poisoning Patient)

  • 김은영;정성필;고동률;공태영;유제성;좌민홍;김민정
    • 대한임상독성학회지
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    • 제16권2호
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    • pp.149-156
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    • 2018
  • Purpose: The purpose of this study was to determine whether hepatotoxicity could be predicted early using biochemical markers in patients with acetaminophen (AAP) poisoning and to assess the usefulness of predictive factors for acute liver injury or hepatotoxicity. Methods: This study was a retrospective observational study involving a medical records review. The participants were patients who were admitted to the emergency department (ED) with AAP overdose at two hospitals over a 10-year period. Demographic data, age, time from ingestion to visit, initial AAP level, initial hepatic aminotransferases, and initial prothrombin time were recorded. Acute liver injury was defined as a peak serum ALT >50 U/L or double the admission value, and hepatotoxicity was defined as a peak ALT >1,000 U/L. Receiver operating characteristic curve analyses were performed to compare the prognostic performance among variables. Results: A total of 97 patients were admitted to the ED with AAP overdose, of whom 26 had acute liver injury and 6 had hepatotoxicity. Acute liver injury was associated with the time interval after taking the drug, and hepatotoxicity was associated with the initial PT and the ALT level. The scoring system proposed by the authors has a significant ability to predict both acute liver injury and hepatotoxicity. Conclusion: To predict the prognosis of AAP poisoning patients, the time interval after taking AAP was important, and initial prothrombin time and ALT level were useful tests. Also a scoring system combining variables may be useful.

생체시료를 이용한 프탈레이트의 실내 노출인자 연구 (Study on the indoor exposure factors of phthalates using bio-monitoring data)

  • 양지연;신동천;이시은;이건우;김준혁;이용진;임영욱
    • 실내환경 및 냄새 학회지
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    • 제17권4호
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    • pp.315-321
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    • 2018
  • Phthalate is an endocrine disruptor that interferes with homeostasis and developmental regulation. It is highly toxic to the environment and is associated with various diseases of the human body. Using biological samples from 140 adult subjects, to evaluate the influencing factors which are related to contaminant concentration levels, we used correlation analysis and multiple regression analysis. Lastly, in order to analyze the health effects related to exposure to phthalates, we conducted a risk assessment by estimating acceptable daily intake exposure according to the influential factors. When we compared the concentration level according to influential factors, in general, the subjects who had engaged in home remodeling work had higher urinary phthalate metabolite concentrations levels than the subjects who had not engaged in home remodeling work. We can confirm statistically significant differences in DBP metabolites. In addition, we can confirm the concentration appeared higher in the categories such as using air freshener, sofa and foods. Through conducting a risk assessment of DEHP, BBzP, DiBP, and DnBP by using data on phthalate metabolite concentration in urine, it was found that the average concentration of all metabolites did not exceed TDI.

3T3-L1 지방전구세포에 대한 다양한 주파수 진동의 지방 생성 억제 효과 (Anti-adipogenic Effects of Vibration with Varied Frequencies on 3T3-L1 Preadipocytes)

  • 이영훈;이석호;정혜빈;정용찬;김민환;이은미;김지현
    • 대한의용생체공학회:의공학회지
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    • 제42권1호
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    • pp.18-24
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    • 2021
  • Vibration is a mechanical cue that can be applied to adipose tissues for the purpose of treating obesity. However, the exact correlation between vibration and other anti-adipogenic pathways, such as development of cytoskeleton and apoptosis, remains unknown. The objective of this study was to investigate the unknown anti-adipogenic effects of vibration with varied frequencies on preadipocytes. 3T3-L1 preadipocytes were cultured in Dulbecco's modified Eagle's medium (DMEM) containing 5% calf serum at 37 ℃ with 5% CO2 in a humidified incubator. Vibration was generated using Arduino Uno microcontroller and vibration motor module with 1 V DC, and applied to preadipocytes for 3 days. Frequency conditions were set to 20, 55, and 90 Hz. Then, the expressions of p38 pathway, ROCK-1, α-actinin, Bax, Bcl-2, caspase-9, 8, and 3 were analyzed with western blot. As a result, p38 pathway was inhibited in 55 and 90 Hz while ROCK-1 and α-actinin were expressed in 20 Hz. Caspase-3, a terminal apoptotic factor, was activated in 20 Hz via extrinsic pathway rather than intrinsic pathway. Results suggest that various frequencies of vibration can inhibit adipogenesis via different pathways which sheds light on future mechanotransduction applications of vibration for the treatment of obesity.

자동차 시트의 인간공학적 디자인에 따른 착좌 안락감 및 압력분포 평가 (Evaluation of Seat Comfort and Pressure Distribution According to the Ergonomic Design of Automobile Seats)

  • 정하림;최준원;양승완;박준규;김도용;송창현;김종배;김한성
    • 대한의용생체공학회:의공학회지
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    • 제44권2호
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    • pp.157-165
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    • 2023
  • The purpose of this study was to evaluate the importance of developing slim seats with ergonomic design to improve seat comfort and expand the interior space. Two seats were used for the experiment: a sample seat designed based on hip shape and spinal alignment and a normal seat with a flat design without curves. Subjects sat in both the sample seat and a normal seat applied to the vehicle simulator and the experiment was conducted. The next part of the experiment was conducted in two different postures: a driving posture and a relaxed posture. The subjects filled out a comfort questionnaire immediately after sitting and after 30 minutes. The results showed that the comfort in the sample seat was found to be more comfortable than the normal seat. However, no significant difference was noted for the relaxation posture. Pressure distribution was also recorded immediately after sitting and after 30 minutes. In the case of pressure distribution, it was confirmed that the pressure in the sample seat was more evenly distributed in both the driving and relaxed postures than in the normal seat. The results showed that the ergonomically designed sample seat greatly improved seating comfort and pressure distribution compared to the normal seat, which is a general vehicle seat design.

연도별 흡연율 및 간접흡연율 추이 분석: 2015-2020 (Trend of Smoking and Second-Hand Smoke Rate: Year 2015-2020)

  • 남지웅;장국영;김기현;김청년;송지수;노진원;유기봉
    • 보건행정학회지
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    • 제33권1호
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    • pp.85-106
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    • 2023
  • Background: The Korean government has established Health Plan and reinforced tobacco control policies step by step according to Framework Convention on Tobacco Control (FCTC). This study aims to investigate yearly smoking and secondhand smoking (SHS) exposure rates adjusted by demographic and socioeconomic factors. Methods: Multiple logistic regression analysis was conducted about the smoking experience, current smoking, and exposure to SHS at home, at work, and in public places using data from the 6th to 8th Korea National Health and Nutrition Examination Survey (2015-2020). Results: Comparing 2015 with other years, smoking experience rates significantly decreased from 2015 to 2018 in men and significantly increased from 2018 to 2020 in women. Compared to 2015, current smoking rates significantly decreased only in 2020 for men and significantly increased in 2018 and 2019 for women. The rate of exposure to SHS at home significantly decreased until 2018. Rates of exposure to SHS in the workplace and public places were significant all year. Conclusion: There were a slowly decreasing trend in men and an increasing trend in women at current smoking rates. It was found that there were significant decreasing trends at exposure to SHS. There is a need to set policies that reduce current smoking rates and especially to set a customized program to lower women's smoking rates.