• Proceedings of the Korean Society for Bioinformatics Conference
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• 2006.02a
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• pp.109-114
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• 2006

최근 Human 지놈 프로젝트를 포함한 다양한 종의 지놈 프로젝트가 수행되고 수많은 지놈정보가 생산되고 있으며 이를 해석하고 서로 연관성를 찾기 위한 다양한 연구가 진행되고 있다. 즉 최신 생명공학과 관련된 연구방향이 DNA의 구조적 해석에서 기능 해석과 유전자들의 상호연관성을 규명하는 방향으로 변화하고 있으며 이를 위한 강력한 도구로서 DNA microarray (DNA chip)는 방대한 양의 지놈 정보를 이용하여 단시간에 대량으로 고속처리하여 효율적으로 유전자 기능을 분석할 수 있는 주목받고 있는 방법이다. DNA microarray 실험과 분석에 있어 데이터분석, 재현성, 종간의 비교, 확인실험 및 비용 등의 문제가 있지만 유전자발현양상 데이터로부터 정확한 환자의 예후를 예측할 수 있는 비교적 적은 유전자 그룹의 진단마커를 찾거나, 하나의 유전자가 아니라 mouse 전체 지놈의 유전자발현 패턴을 인간의 암을 위시한 각종 질병 연구를 위한 발현 신호나 변화 등을 발견하여 신약개발 등에 활용하고자 하는 시도가 활발히 진행되고 있다. 서로 다른 종간에 비슷한 phenotype의 유전자발현도 진화적으로 보존되었다는 전제 하에서 지놈 sequence의 비교연구가 가능하고 DNA microarray 발현 데이터에 근거하여 독립적으로 각 종간의 유전자발현패턴을 비교함으로써 난치병 등을 새롭게 분류할 수 있다. 즉, 암세포 등에서 유전자발현 양상은 유전학적, 환경적 alteration들이 잘 반영되어 있다고 간주하고, 이러한 양상을 바탕으로 인간의 암을 위시한 다양한 질병 연구를 위한 최적의 mouse 모델을 찾을 수 있고, 이는 결국 새로운 치료 방법 개발이나 맞춤의학 실현에 중요한 역할을 할 것으로 기대된다. 특히 pathway 타겟으로 하는 치료를 위해서는 Human-mouse 비교를 통한 발현 신호를 찾는 것이 진단에서는 매우 유용한 방법이다. 이를 위한 고성능의 분석방법이나 시스템의 개발이 중요하게 된다.. 관류의 정도와 조영증강정도를 중심으로 관류 MR 영상소견과 조직학적 소견을 관련지어 분석하였다. 결과: 조영증강 T1강조MR영상에서 환상조영증강을 보이는 다형성 교보세포종 2예에서는 변연부 외륜이 고관류를, 중심부의 괴사부위는 저관류로 나타났다. 저등급 교종은 경계가 불분명한 저관류부위로 보였다. 뇌농양 2예는 변연부 외륜이 경도의 고관류를, 중심부는 저관류로 나타났다. 뇌수막종은 미만성의 균일한 중등도 혹은 고도의 고관류로 보였으며, 임파종과 배아종은 경계가 명확한 저관류부위로 나타났다. 신경세포종은 종괴\ulcorner 일부에 중등도 혹은 고도의 고관류부위가 관찰되었고, 전이암은 다수병변중 일부에서 중등도의 고관류를 보였다. 방사선괴사는 저관류부위내에 국소적 고관류부위를 보였다. 결론: 관류 MR영상은 뇌종양의 관류상태를 비교적 잘 반영하며, 조직학적 특성을 예측하는데에 도움을 주 수 있을 것으로 기대된다. 뇌종야에서의 관류MR영상의 분명한 역할을 규명하기 위해서는 앞으로 더 많은 임상적 연구가 필요할 것으로 생각된다.조증 환자의 자극성 전타액내 lactobacilli양은 peroxidase system을 함유한 세치제를 사용한 군에서 대조군에 비해 상대적으로 낮게 나타났으나(p = 0.067) 통계학적 유의성은 없었다.같은 예에서 찾아 볼 수 있다. 첫째, 발음상으로 동사의 변화형에서 "porte[$p{\jmath}rte$](들다: 현재형), porte[$p{\jmath}rte$](과거분사형), porta[$p{\jmath}rte$](단순과거형)"등이 대립되며, 이휘 "Porto[$p{\jmath}rte$](포르토)"와도 대립된다. 둘째, 어휘적 대립 "le haut[$l{\partial}o$](위)/l'eau[lo](물)"와 형태론적 대립 "le[$l{\partial}$](정관사, 남성단수)/l

• Sleep Medicine and Psychophysiology
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• v.6 no.2
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• pp.143-148
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• 1999

Objectives: We studied correlations between neuropsychological tests and perceptual disorder in patients with head trauma and psychiatric patients in order to explore the functional localization of brain in perceptual disorders. Methods: Halstead Reitan Neuropsychological Test Battery, Korean Wechsler Intelligent Scale, and Minnesota Multiphasic Peronality Inventory(MMPI) were administered to one hundred ninteen patients consisting of sixty nine psychiatric patients and fifty patients with brain damage. We tested the correlation between results of neuropsychological tests and peceptual disorder scale PDS) made from nine items related with perceptual disorder in MMPI. T-tests between twenty one higher scorers and seventeen lower scorers of PDS were also performed in the psychiatric group. Results: In brain damage group, significant correlations were found in tests related with function of frontal lobe such as category tests, trail making tests, tactual performance test, and fingertip number writing test, and significant correlations were also noted in the tests related with function of right hemisphere such as tactual performance test, performance, picture completion, picture arrangement and block design. Tests related with subcortical function such as digit symbol test, arithmetic and digit span were signigicantly correlated, too. In psychiatric group, there were significant differences of PDS in the tests related with function of right hemisphere such as picture completion, block design, and right laterality index, and in the tests related with function of left hemisphere such as comprehension, vocabulary, and similarities. Conclusion: Perceptual disorder seems to be related with functions of frontal lobe, right hemisphere, and subcortex in both groups. In a psychiatric group, left hemisphere may be also partially related with perceptual disorder.

• Journal of KIISE:Computing Practices and Letters
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• v.6 no.3
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• pp.364-372
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• 2000

Subcategorization, defining dependency relation between predicates and their complements, is an important source of knowledge for resolving syntactic and semantic ambiguities arising in analyzing sentences. This paper describes a Korean subcategorization dictionary, particularly annotated with semantic roles of complements coupled with thesaural semantic hierarchy as well as syntactic dependencies. For annotating roles, we defined 25 semantic roles associated with surface case markers that can be used to derive semantic structures directly from syntactic ones. In addition, we used more than 120,000 entries of thesaurus to specify concept markers of noun complements, and also used 47 and 17 predicate patterns for verbs and adjectives, respectively, to express dependency relation between predicates and their complements. Using a full-fledged thesaurus for specifying concept markers makes it possible to build an effective selectional restriction mechanism coupled with the subcategorization dictionary, and using the standard predicate patterns for specifying dependency relations makes it possible to avoid inconsistency in the results and to reduce the costs for constructing the dictionary. On the bases of these, we built a Korean subcategorization dictionary for frequently used 13,000 predicates found in corpora with the aid of a tool specially designed to support this task. An experimental result shows that this dictionary can provide 72.7% of predicates in corpora with appropriate subcategorization information.

• The Journal of Sustainable Design and Educational Environment Research
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• v.19 no.4
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• pp.40-49
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• 2020

Recently, the form of education has changed from one-way to two-way and mutual exchange rather than the existing one-way order form, and accordingly, it is necessary to consider creating a suitable learning environment for each type of education. The basic form of education consists of the delivery of knowledge, that is, the delivery of knowledge by teachers to education consumers through voice delivery, so the sound environment is considered an essential factor in creating a pleasant learning environment. The indoor sound environment is very closely related to the mental stress of the inmate, so the quality level of education will also change greatly depending on whether or not the appropriate sound environment is created. However, the importance of the sound environment in educational facilities such as classrooms has not been highlighted due to the lack of research and related laws on the sound environment. Therefore, in this study, auditory tests were conducted using the auralization based on the physical acoustic performance data presented in the preceding study. Through this, we wanted to verify the validity of this research by analyzing the subjective acoustic performance satisfaction of the occupants due to the improvement of the physical acoustic performance. Based on these research results, it is estimated that the improvement of the sound environment of educational facilities through remodeling in the future will be possible to verify whether the sound environment suitable for educational facilities is created only after the analysis stage on the improvement of subjective sound performance as well as physical sound performance.

• The Journal of the Korea Contents Association
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• v.20 no.11
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• pp.492-500
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• 2020

The purpose of this study was to investigate (1) the aspect of the correlation among subcategories in English reading anxiety, (2) the aspect of the cause and effect relation. The reading anxiety was measured by a questionnaire. Then, the results were analyzed by SPSS program. The findings of this study were as follows: First, most of the sub-elements in reading anxiety in both groups correlate with one another even though the overall coefficient of correlation in high achievement group is rather higher. Second, it is also found that the lack of confidence for reading has negative influence on entire reading anxiety in both groups, which is followed by lengthy reading, evaluation and general anxieties in consecutive order. The implication of this study is that the teachers and students should be aware that the constituents of reading anxiety not only correlate with one another, but have great deal of relative influence on reading process. Therefore, teachers should organize a learning environment where learners can minimize the feeling of anxiety.

• Journal of the Korean Society for Library and Information Science
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• v.40 no.3
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• pp.289-304
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• 2006

The purpose of this pilot study is to construct a searching thesaurus with word association test in the library and information science field and to confirm it's functionality as searching aids through query expansion experiments. The test results were analyzed to four types of relationship between stimulus words and response words, and the terms of association thesaurus were compared with descriptors of an existing thesaurus. The test results show that the word association test is a fruitful method to identify many related terms and narrower and equivalent terms in some degree to the stimulus terms. Furthermore. in the query expansion experiment. the Performance of association thesaurus was better than that of an existing thesaurus, This result demonstrates that word association thesaurus can apply to query expansion.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.6
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• pp.1034-1044
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• 2016

This study seeks a method to objectively evaluate sensibility based on Big Data in the field of design. In order to do so, this study examined the sensibility responses on design factors for the public through a network analysis of texts displayed in social media. 'Hanbok', a formal clothing that represents Korea, was selected as the subject for the research methodology. We then collected 47,677 keywords related to Hanbok from 12,000 posts on Naver blogs from January $1^{st}$ to December $31^{st}$ 2015 and that analyzed using social matrix (a Big Data analysis software) rather than using previous survey methods. We also derived 56 key-words related to design elements and sensibility responses of Hanbok. Centrality analysis and CONCOR analysis were conducted using Ucinet6. The visualization of the network text analysis allowed the categorization of the main design factors of Hanbok with evaluation terms that mean positive, negative, and neutral sensibility responses. We also derived key evaluation factors for Hanbok as fitting, rationality, trend, and uniqueness. The evaluation terms extracted based on natural language processing technologies of atypical data have validity as a scale for evaluation and are expected to be suitable for utilization in an index for sensibility evaluation that supplements the limits of previous surveys and statistical analysis methods. The network text analysis method used in this study provides new guidelines for the use of Big Data involving sensibility evaluation methods in the field of design.

• Cross-Cultural Studies
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• v.51
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• pp.291-327
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• 2018

'Hyesung' and 'Jeilsun' are media that reveal the new searches of the Gaebyeoksa Publishing Company of the 1930s. However, studies in the past did not sufficiently analyze their significance. Furthermore, there are no analyses on how the critical minds of 'Hyesung' and 'Jeilsun' were linked to 'Gaebyeok', which continued publications in 1934. The 1930s when 'Hyesung' and 'Jeilsun' were published, was a time where the media of colonial Chosun was rapidly changing, and it was a time where literary magazines were increasing in quantity. In the 1930s, Gaebyeoksa attempted to actively respond to such changes reflected in the media. This was demonstrated through the publication of the new media 'Hyesung' and 'Jeilsun' and continuing publication of the 'Gaebyeok' magazine in 1935. This study analyzed the literary discourses shown in the magazines published by Gaebyeoksa in the 1930s based on 'Hyesung', 'Jeilsun', and the continued publication of 'Gaebyeok'. Through such analysis, this study examined how the magazines published by Gaebyeoksa perceived the culture and literature of colonial Chosun in the 1930s and in which direction it tried to reorganize this.

• Annual Conference on Human and Language Technology
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• 2001.10d
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• pp.260-266
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• 2001

본 논문은 불어 명사의 의미 통사적 분류와 관련된 '대상부류(classes d'objets)' 이론을 바탕으로 한국어의 "크기" 명사 부류에 대한 의미적, 형식적 기준을 설정함으로써 자연언어 처리에의 활용 방안을 모색하고자 한다. 한국어의 일부 명사들은 어떤 대상 혹은 현상의 다양한 속성이 특정 차원에서 갖는 규모의 의미를 표현한다 예를 들어, '길이', '깊이', '넓이', '높이', '키', '무게', '온도', '기온' 등이 이에 해당하는데, 이들은 측정의 개념과도 밀접한 연관을 가지며, 통사적으로도 일정한 속성을 공유한다. 즉 '측정하다', '재다' 등 측정의 개념을 나타내는 동사 및 수량 표현과 더불어 일정한 통사 형식으로 실현된다는 점이다. 본 논문에서는 이러한 조건을 만족시키는 한국어 명사들을 "크기" 명사라 명명하며, "크기" 명사와 특징적으로 결합하는 '측정하다', '재다' 등의 동사를 "크기" 명사 부류에 대한 적정술어라 부른다. 또한 "크기" 명사는 결합 가능한 단위명사의 종류 및 호응 가능한 정도 형용사의 종류 등에 따라 세부 하위유형으로 분류할 수도 있다. 따라서 주로 술어와의 통사적 결합관계를 기준으로 "크기" 명사 부류를 외형적으로 한정하고, 이 부류에 속하는 개개 명사들의 통사적 세부 속성을 전자사전의 체계로 구축한다면 한국어 "크기" 명사에 대한 전반적이고 총체적인 의미적 통사적 분류와 기술이 가능해질 것이다. 한편 "크기" 명사에 대한 연구는 반드시 이들 명사를 특징지어주는 단위명사 부류의 연구와 병행되어야 한다. 본 연구는 한국어 "크기" 명사를 한정하고 분류하는 보다 엄밀하고 형식적인 기준과 그 의미 통사 정보를 체계적으로 제시해 줄 것이다. 이러한 정보들은 한국어 자동처리에 활용되어 "크기" 명사를 포함하는 구문의 자동분석 및 산출 과정에 즉각적으로 활용될 수 있을 것이다. 또한, 이러한 정보들은 현재 구축중인 세종 전자사전에도 직접 반영되고 있다.teness)은 언화행위가 성공적이라는 것이다.[J. Searle] (7) 수로 쓰인 것(상수)(象數)과 시로 쓰인 것(의리)(義理)이 하나인 것은 그 나타난 것과 나타나지 않은 것들 사이에 어떠한 들도 없음을 말한다. [(성중영)(成中英)] (8) 공통의 규범의 공통성 속에 규범적인 측면이 벌써 있다. 공통성에서 개인적이 아닌 공적인 규범으로의 전이는 규범, 가치, 규칙, 과정, 제도로의 전이라고 본다. [C. Morrison] (9) 우리의 언어사용에 신비적인 요소를 부인할 수가 없다. 넓은 의미의 발화의미(utterance meaning) 속에 신비적인 요소나 애정표시도 수용된다. 의미분석은 지금 한글을 연구하고, 그 결과에 의존하여서 우리의 실제의 생활에 사용하는 $\ulcorner$한국어사전$\lrcorner$ 등을 만드는 과정에서, 어떤 의미에서 실험되었다고 말할 수가 있는 언어과학의 연구의 결과에 의존하여서 수행되는 철학적인 작업이다. 여기에서는 하나의 철학적인 연구의 시작으로 받아들여지는 이 의미분석의 문제를 반성하여 본다.반인과 다르다는 것이 밝혀졌다. 이 결과가 옳다면 한국의 심성 어휘집은 어절 문맥에 따라서 어간이나 어근 또는 활용형 그 자체로 이루어져 있을 것이다.으며, 레드 클로버 + 혼파 초지가 건물수량과 사료가치를 높이는데 효과적이었다.\ell}$ 이었으며 , yeast extract 첨가(添加)하여 배양시(培養時)는 yeast extract 농도(濃度)가 증가(增加)함에 따라 단백질(蛋白質) 함량(含量)도 증가(增加)하였다. 7. CHS-13 균주(菌株)의 RNA 함량(含量)은 $4.92{\times}10^{-2 }\;mg/m{\ell}$이었으며 yeast extract 농도(濃度)가 증가(增加)함에 따라 증가(增加)하다가 농도(濃度) 0.2%에서 최대함량(最大含量)을 나타내고 그후는 감소(減少)하였다.

• Korean Journal of Culture and Social Issue
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• v.21 no.1
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• pp.67-96
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• 2015

Do cultural differences affect moral decisions? Two studies were conducted to investigate whether attitudes of individualism vs. collectivism have an impact on ethical decision making. Study 1 (N=92) showed that utilitarianism was preferred in a situation, in which an intervention resulted in the best outcome (i.e., saving more people's lives), while deontology was preferred in a situation, in which the focus was on negative consequences of the intervention (i.e. personal sacrifices). Additionally, there were differences between the idiocentrics and the allocentrics groups regarding morality aspects. In the idiocentrics group, harm and fairness were regarded as more important than other moral aspects, while in the allocentrics group, not only harm and fairness, but also ingroup and authority were perceived as critical moral aspects. In Study 2 (N=30), after lexical decision tasks were conducted for culture priming, the mouse tracking method was used to explore response dynamics of moral decision processes, while judging appropriateness of interventions in moral dilemmas. In Study 2, in a condition, in which the small number of victims were focused upon, there were more maximal deviations and higher X_flips in the individualism priming group than in the collectivism priming group, which showed that the participants in the individualism condition had more deliberative processes before choosing their answers between utilitarianism and deontology. In addition, the participants in the individualism priming condition showed more maximal deviations in the mouse trajectories regarding ingroup related interventions in moral dilemmas than those in the collectivism priming condition. These results implicated the possibilities that the automatic emotional process and the controlled deliberative process in moral decision making might interact with cultural dispositions of the individuals and the focus of situations.