• Title/Summary/Keyword: 어레이센서

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Machine Vision Platform for High-Precision Detection of Disease VOC Biomarkers Using Colorimetric MOF-Based Gas Sensor Array (비색 MOF 가스센서 어레이 기반 고정밀 질환 VOCs 바이오마커 검출을 위한 머신비전 플랫폼)

  • Junyeong Lee;Seungyun Oh;Dongmin Kim;Young Wung Kim;Jungseok Heo;Dae-Sik Lee
    • Journal of Sensor Science and Technology
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    • v.33 no.2
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    • pp.112-116
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    • 2024
  • Gas-sensor technology for volatile organic compounds (VOC) biomarker detection offers significant advantages for noninvasive diagnostics, including rapid response time and low operational costs, exhibiting promising potential for disease diagnosis. Colorimetric gas sensors, which enable intuitive analysis of gas concentrations through changes in color, present additional benefits for the development of personal diagnostic kits. However, the traditional method of visually monitoring these sensors can limit quantitative analysis and consistency in detection threshold evaluation, potentially affecting diagnostic accuracy. To address this, we developed a machine vision platform based on metal-organic framework (MOF) for colorimetric gas sensor arrays, designed to accurately detect disease-related VOC biomarkers. This platform integrates a CMOS camera module, gas chamber, and colorimetric MOF sensor jig to quantitatively assess color changes. A specialized machine vision algorithm accurately identifies the color-change Region of Interest (ROI) from the captured images and monitors the color trends. Performance evaluation was conducted through experiments using a platform with four types of low-concentration standard gases. A limit-of-detection (LoD) at 100 ppb level was observed. This approach significantly enhances the potential for non-invasive and accurate disease diagnosis by detecting low-concentration VOC biomarkers and offers a novel diagnostic tool.

Signal Analysis of Optical Biosensor to Detect Peroxide Using Electrically Controlled Release System (전기적 방출 조절 시스템을 이용한 광 페록사이드센서의 개발)

  • Min, Jun-Hong;Lim, In-Hee;Kim, Hyo-Han;Lee, Sang-Beak;Choi, Jeong-Woo;Lee, Won-Hong
    • Journal of Sensor Science and Technology
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    • v.6 no.1
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    • pp.35-42
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    • 1997
  • The optical biosensor using the electrically controlled release of reactive reagent is developed for the detection of peroxide. Rapid degradation of polymer complex of PEOx and PMAA occurs as the applied current increases and thus released amount of HPA increases. The degradation velocity of polymer and the amount of HPA released are linearly proportional to the applied current. Peroxide is reacted with the released reagent by peroxidase and then the product, a fluorescent dimer DBDA, is formed. The monochromic light from light source (150W Xe arc ramp) excites the DBDA and the excited light is transmitted through an optical fiber to be detected by a photodiode array. The change of fluorescence intensity is related to the change of peroxide concentration. The peroxidase is entrapped in Ca-alginate get on the inner surface. The biosensor has the linear signal range of 0.025mM-10.mM peroxide. By applying the step function of peroxide, reproducibility of biosensor has been investigated. The mathematical model is constructed by the combination of enzyme kinetics with reactor flow model. Good agreement is obtained between the experimental result and model prediction in the sensor signal.

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The fabrication and sensing characteristics of conducting polymer sensors for Measurement of VOCs (Volatile organic compounds) gas (휘발성 유기 화합물 가스 측정을 위한 전도성 고분자 센서의 제조(製造) 및 감응(感應) 특성(特性))

  • Paik, J.H.;Hwang, H.R.;Roh, J.G.;Huh, J.S.;Lee, D.D.;Lim, J.O.;Byun, H.G.
    • Journal of Sensor Science and Technology
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    • v.10 no.2
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    • pp.125-133
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    • 2001
  • Conducting polymer sensors show high sensitivity when exposed to volatile organic compounds gases at room temperature. The 8 sensor array using by polypyrrole and polyaniline has been fabricated by chemical polymerization for measuring sensing characteristics of VOCs gases. Conducting polymer was polymerized by using distilled pyrrole, aniline as a monomer and ammonium persulfate (APS) as an oxidant and dodecylbenzene sulfonic acid (DBSA) as a dopant. Dedoped film was synthesized by reverse voltage and redoped film was synthesized by using 1-octanesulfonic acid sodium salt as another dopant in electrochemical cell. The sensitivity and reversibility were influenced by doping, dedoping, redoping and thickness for the polypyrrole and polyaniline. We investigated the relation between the structure of conducting polymer and sensitivity of these sensors through the analysis of scanning electron microscope (SEM), scanning probe microscope (SPM) and $\alpha$-step.

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Design of Small-Area eFuse OTP Memory for Line Scan Sensors (Line Scan Sensor용 저면적 eFuse OTP 설계)

  • Hao, Wenchao;Heo, Chang-Won;Kim, Yong-Ho;Ha, Pan-Bong;Kim, Young-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.8
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    • pp.1914-1924
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    • 2014
  • In this paper, a small-area cell array method of reducing number of SL drivers requiring large layout areas, where the SL drivers supplying programming currents are routed in the row direction in stead of the column direction for eFuse OTP memory IPs having less number of rows than that of columns such as a cell array of four rows by eight columns, and a core circuit are proposed. By adopting the proposed cell array and core circuit, the layout area of designed 32-bit eFuse OTP memory IP is reduced. Also, a V2V ($=2V{\pm}10%$) regulator necessary for RWL driver and BL pull-up load to prevent non-blown eFuse from being blown from the EM phenomenon by a big current is designed. The layout size of the designed 32-bit OTP memory IP having a cell array of four rows by eight columns is 13.4% smaller with $120.1{\mu}m{\times}127.51{\mu}m$ ($=0.01531mm^2$) than that of the conventional design with $187.065{\mu}m{\times}94.525{\mu}m$ ($=0.01768mm^2$).

Performance Prediction for Plenoptic Microscopy Under Numerical Aperture Unmatching Conditions (수치 구경 불일치 플렌옵틱 현미경 성능 예측 방안 연구)

  • Ha Neul Yeon;Chan Lee;Seok Gi Han;Jun Ho Lee
    • Korean Journal of Optics and Photonics
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    • v.35 no.1
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    • pp.9-17
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    • 2024
  • A plenoptic optical system for microscopy comprises an objective lens, tube lens, microlens array (MLA), and an image sensor. Numerical aperture (NA) matching between the tube lens and MLA is used for optimal performance. This paper extends performance predictions from NA matching to unmatching cases and introduces a computational technique for plenoptic configurations using optical analysis software. Validation by fabricating and experimenting with two sample systems at 10× and 20× magnifications resulted in predicted spatial resolutions of 12.5 ㎛ and 6.2 ㎛ and depth of field (DOF) values of 530 ㎛ and 88 ㎛, respectively. The simulation showed resolutions of 11.5 ㎛ and 5.8 ㎛, with DOF values of 510 ㎛ and 70 ㎛, while experiments confirmed predictions with resolutions of 11.1 ㎛ and 5.8 ㎛ and DOF values of 470 ㎛ and 70 ㎛. Both formula-based prediction and simulations yielded similar results to experiments that were suitable for system design. However, regarding DOF values, simulations were closer to experimental values in accuracy, recommending reliance on simulation-based predictions before fabrication.

Design of a CMOS x-ray line scan sensors (CMOS x-ray 라인 스캔 센서 설계)

  • Heo, Chang-Won;Jang, Ji-Hye;Jin, Liyan;Heo, Sung-Kyn;Kim, Tae-Woo;Ha, Pan-Bong;Kim, Young-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.10
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    • pp.2369-2379
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    • 2013
  • A CMOS x-ray line scan sensor which is used in both medical imaging and non-destructive diagnosis is designed. It has a pixel array of 512 columns ${\times}$ 4 rows and a built-in DC-DC converter. The pixel circuit is newly proposed to have three binning modes such as no binning, $2{\times}2$ binning, and $4{\times}4$ binning in order to select one of pixel sizes of $100{\mu}m$, $200{\mu}m$, and $400{\mu}m$. It is designed to output a fully differential image signal which is insensitive to power supply and input common mode noises. The layout size of the designed line scan sensor with a $0.18{\mu}m$ x-ray CMOS image sensor process is $51,304{\mu}m{\times}5,945{\mu}m$.

Hand Gesture Recognition Regardless of Sensor Misplacement for Circular EMG Sensor Array System (원형 근전도 센서 어레이 시스템의 센서 틀어짐에 강인한 손 제스쳐 인식)

  • Joo, SeongSoo;Park, HoonKi;Kim, InYoung;Lee, JongShill
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.11 no.4
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    • pp.371-376
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    • 2017
  • In this paper, we propose an algorithm that can recognize the pattern regardless of the sensor position when performing EMG pattern recognition using circular EMG system equipment. Fourteen features were extracted by using the data obtained by measuring the eight channel EMG signals of six motions for 1 second. In addition, 112 features extracted from 8 channels were analyzed to perform principal component analysis, and only the data with high influence was cut out to 8 input signals. All experiments were performed using k-NN classifier and data was verified using 5-fold cross validation. When learning data in machine learning, the results vary greatly depending on what data is learned. EMG Accuracy of 99.3% was confirmed when using the learning data used in the previous studies. However, even if the position of the sensor was changed by only 22.5 degrees, it was clearly dropped to 67.28% accuracy. The accuracy of the proposed method is 98% and the accuracy of the proposed method is about 98% even if the sensor position is changed. Using these results, it is expected that the convenience of the users using the circular EMG system can be greatly increased.

Design of a Vision Chip for Edge Detection with an Elimination Function of Output Offset due to MOSFET Mismatch (MOSFET의 부정합에 의한 출력옵셋 제거기능을 가진 윤곽검출용 시각칩의 설계)

  • Park, Jong-Ho;Kim, Jung-Hwan;Lee, Min-Ho;Shin, Jang-Kyoo
    • Journal of Sensor Science and Technology
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    • v.11 no.5
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    • pp.255-262
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    • 2002
  • Human retina is able to detect the edge of an object effectively. We designed a CMOS vision chip by modeling cells of the retina as hardwares involved in edge detection. There are several fluctuation factors which affect characteristics of MOSFETs during CMOS fabrication process and this effect appears as output offset of the vision chip which is composed of pixel arrays and readout circuits. The vision chip detecting edge information from input image is used for input stage of other systems. Therefore, the output offset of a vision chip determine the efficiency of the entire performance of a system. In order to eliminate the offset at the output stage, we designed a vision chip by using CDS(Correlated Double Sampling) technique. Using standard CMOS process, it is possible to integrate with other circuits. Having reliable output characteristics, this chip can be used at the input stage for many applications, like targe tracking system, fingerprint recognition system, human-friendly robot system and etc.

Development and Application of Polymer-based Flexible Force Sensor Array (폴리머 재료를 이용한 유연 수직/수평 힘 센서 어레이 개발 및 응용)

  • Hwang, Eun-Soo;Yoon, Young-Ro;Yoon, Hyoung-Ro;Shin, Tae-Min;Kim, Yong-Jun
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.5
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    • pp.142-149
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    • 2009
  • This paper proposes and demonstrates novel flexible contact force sensing devices for 3-dimensional force measurement. To realize the sensor, polyimide and polydimethylsiloxane are used as a substrate, which makes it flexible. Thin-film metal strain gauges, which are incorporated into the polymer, are used for measuring the three-dimensional contact forces. The force sensor characteristics are evaluated against normal and shear load. The fabricated force sensor can measure normal loads up to 4N. The sensor output signals are saturated against load over 4N. Shear loads can be detected by different voltage drops in strain gauges. The device has no fragile structures; therefore, it can be used as a ground reaction force sensor for balance control in humanoid robots. Four force sensors are assembled and placed in the four corners of the robot's sole. By increasing bump dimensions, the force sensor can measure load up to 20N. When loads are exerted on the sole, the ground reaction force can be measured by these four sensors. The measured forces can be used in the balance control of biped locomotion system.

A wavelength readout of a fiber-optic tunable laser using a double-pass Mach-Zehnder Interferometer (더블패스 마하젠더 간섭계를 이용한 광섬유 레이저의 파장검출)

  • Park, Hyong-Jun;Kim, Hyun-Jin;Song, Min-Ho
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.46 no.1
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    • pp.43-48
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    • 2009
  • We constructed a simple wavelength readout system for a tunable fiber laser which was used for a fiber Bragg grating sensor array system. A quadrature sampling method was used to demodulate wavelength variations of the tunable laser which consisted of a SOA(semi-conductor optical amplifier) and a fiber-optic Fabry-Perot filter. Internal triggers, which have a 90 degree phase period, have been generated by using a double-pass Mach-Zehnder interferometer. From Lissajous plots with quadrature sampled data, a mean phase error of ${\sim}2.51$ mrad was obtained. From the wavelength readout experiments, an accurate and fast linear wavelength demodulation has been confirmed.