• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.5
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• pp.479-484
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• 2007

A case of epithelial-myoepithelial carcinoma transformed in pleomorphic adenoma occurring in palate of a 61 years old woman is reported. The tum or was composed of 2 different components, pleomorphic adenoma and epithelial myoepithelial carcinoma, accounting for approximately 40% and 60% of whole tumor, respectively. As the results of the immunohistopathologic study, epithelial-myoepithelial carcinoma showed multiple tubular or solid nest, which were separated by a basement membrane and considered of variable proportion of 2 cell types, cuboidal epithelial cells positive for cytokeratin and clear myoepithelial cells positive for glial fibrillary acid protein, wheres the myoepithelial nest of pleomorphic adenoma intermingled with hyaline and myxoid stroma. The malignancy was demonstrated by convincing evidence of invasion into the submucosa, although the epithelial-myoepithelial carcinoma component was mostly surrounded by the pleomorphic adenoma componemts. An increased immunoreactivity of proliferating cell nuclear antign in the epithelial myoepithelial carcinoma area in comparison to the pleomorphic adenoma also suggested epithelial-myoepithelial carcinoma arising in a pleomorphic adenoma.

• The Journal of the Korean bone and joint tumor society
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• v.12 no.2
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• pp.136-140
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• 2006

Pelvic bone is location with the worst prognosis in primary malignant bone tumor. Malignant bone tumor around symphysis pubis is extremely rare, and although small size, it is difficult to excise because of anatomical location. The authors report a case of intra-pelvic chondrosarcoma of the pubic bone with good functional result through resection by both superior & inferior pubic ramus osteotomy.

• Journal of Ethics
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• no.94
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• pp.249-275
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• 2014

This study aims to standardize Moral Judgment Test (MJT) for measure the level of moral judgment to apply to Korean society. The questionnaire of MJT was composed of two stories: Worker's Dilemma; Doctor's Dilemma. The procedure of this study was started with translation, making final questionnaire through several times pre-test, survey, then did analyze. The degree of reliability was .669. To verify validity, this study carried 3 kinds of tests as follows: the Order of Preferences, Quasi-simplex Structure, Cognitive-Affective Parallelism. Through these tests, this study showed that Korean-translated version questionnaire of MJT is significant and good base to measure moral judgment.

• Journal of the Korean Arthroscopy Society
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• v.13 no.3
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• pp.242-248
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• 2009

Purpose: To evaluate the clinical and radiologic results of the arthroscopic rotator cuff repair for partial articular surface tendon avulsion lesion. Materials and Methods: Twelve patients with symptomatic, partial articular surface tendon avulsion underwent arthroscopic rotator cuff repair between Mar. 2006 and Sep. 2008. The mean follow-up period was 18.3 months(12~36 months), and the mean age at the time of surgery was 46.9-year-old(19~64 years). Three cases had underwent rotator cuff repair after conversion to full-thickness tear and nine cases had transtendon repair with preserving bursal side cuff. Results: The mean VAS during motion was 6.2 before treatment and 2.0 at final follow-up (p<0.001). The passive forward flexion improved from $163.3^{\circ}$ preoperatively to $169.8^{\circ}$ postoperatively (p=0.038). The mean UCLA score improved from 18.4 preoperatively to 30.1 with 2 excellent, 8 good and 2 fair results at final follow-up. The mean KSS improved from 61.8 preoperatively to 76.8 at final follow-up. By examining the postoperative MR images of 5 patients, complete healing was observed in all of them. Conclusion: Arthroscopic rotator cuff repair may be an effective procedure for partial articular surface tendon avulsion in pain relief and improvement of the range of motion. If the remaining bursal side cuff fibers are intact, transtendon repair procedure with preserving the intact bursal layer of the tendon can be considered. If the remaining bursal side cuff fibers are friable or little, completion from partial-thickness to full-thickness tears with subsequent cuff repair can be considered.

• Journal of the Korean Orthopaedic Association
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• v.55 no.3
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• pp.229-236
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• 2020

Purpose: This study examined the utility of preliminary magnetic resonance imaging (MRI) measurements in the ultrasound-guided L4 selective nerve root block. Materials and Methods: As a retrospective study, 71 patients, who met the criteria for outpatient visits from March 2016 to December 2017, were included. From March 2016 to February 2017, 31 patients who underwent an L4 nerve root block without MRI were classified as group A, and 40 patients who underwent an L4 nerve root block through MRI measurements from March 2017 to December 2017 were classified as group B. Group A was injected under ultrasound-guidance through the pararadicular approach without a pre-interventional MRI evaluation, and group B was injected under ultrasound-guidance according to the preliminary MRI measurements. The results were assessed using the numeric rating scale scores before, three hours, and two, six, and 12 weeks after the procedure. Results: At three hours after the procedure, the proportion of patients better than good results were 51.6% in group A and 67.5% in group B. At two weeks after the procedure, the proportion of patients with better than good results were 48.4% and 70.0% in groups A and B, respectively; 58.1% and 62.5% of patient of groups A and B, respectively, showed better than good results after six weeks. In 12 weeks after the procedure, the results of group A and B were 67.7% and 62.5%, respectively. At three hours and two weeks after the procedure, group B showed significant symptom improvement than group A (p<0.05). The procedures were repeated 2.8 and 1.7 times in groups A and B, respectively, between two and six weeks for satisfactory pain relief (p<0.05). Conclusion: A pre-interventional MRI evaluation might improve pain relief within the initial two weeks after ultrasound-guided L4 selective nerve root block by improving the success rate of the procedure.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.5 no.2
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• pp.43-48
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• 2010

Objectives : This study is designed to evaluate the effect of conservative oriental medical treatment using Chuna manual therapy for meridian sinew system for snapping hip patient who have hip joint movement system impairment. Methods : 28-year old snapping hip patient who have hip joint movement system impairment was treated with conservative oriental medical treatment using Chuna manual therapy for meridian sinew system. The improvement of the patient was evaluated by Numerical rating scale(NRS), Snapping Sound Degree(SSD), Range of Motion(ROM). Results: After 13 times treatment, the patient had significant improvement in Numerical rating scale(NRS), Snapping Sound Degree(SSD), Range of Motion(ROM). Conclusions: If hip joint movement system impairment cause a snapping hip, we can treat with Chuna manual therapy for meridian sinew system.

• Korean Journal of Plant Tissue Culture
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• v.22 no.1
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• pp.29-33
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• 1995

This study was carried out to analyse saikosaponin contents in adventitious root formed from callus of Bupleurum falcatum L. The induction of adventitious root from callus of 4 weeks of culture was most favorable to MS medium supplemented with 0.1 mg/L 2,4-D. The adventitious root formation ratio per callus was highest when the size of callus was 900 to 1,000 $\mu$M The content of saikosaponin a and d was 2089$\pm$124 $\mu$g and 4778 $\pm$ 214 $\mu$g at 150 days of culture respectively on the basis of g dry root wt, whereas that of saikosaponin c was 3492 $\pm$ 123 $\mu$g at 60 days of culture.

• Korean Journal of Plant Resources
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• v.23 no.1
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• pp.14-18
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• 2010

Rosmarinic acid, an ester of caffeic acid with 3,4-dihydroxyphenyl lactic acid, is one of the main active constituents of Agastache rugosa Kuntze and has an astringent property, antioxidant capacity, anti-inflammatory activity, antimutagenic ability, antimicrobial capacity, and an antiviral property. Five different strains of Agrobacterium rhizogenes differed in their ability to induce Korean mint (Agastache rugosa Kuntze) hairy roots and also showed varying effects on the growth and rosmarinic acid production in hairy root cultures. A. rhizogenes R1601 is the most effective strain for the induction (72.90%), growth (13.50 g/l) and rosmarinic acid production (22.60 mg/g) in hairy root of Korean mint. Our results demonstrate that use of suitable strains of A. rhizogenes may allow study of the regulation of rosmarinic acid biosynthesis in hairy root cultures of Agastache rugosa.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.8
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• pp.952-956
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• 2017

An high performance liquid chromatography (HPLC) analysis method was developed for standard determination of coixol as a functional cosmetic material in Coix lachryma-jobi var. ma-yuen roots extract. HPLC was performed on a $C_{18}$ Unison US column ($4.6{\times}250mm$, $5{\mu}m$ column) using a gradient elution of 0.1% (v/v) trifluoroacetic acid and acetonitrile at a flow rate of 1.0 mL/min at $30^{\circ}C$. The analyte was detected at 290 nm. The HPLC method was validated in accordance with the International Conference on Harmonization guideline of analytical procedures with respect to specificity, precision, accuracy, and linearity. The limit of detection and quantitation were 0.07 and 0.25 mg/mL, respectively. Calibration curves showed good linearity ($R^2$>0.9995), and the precision of analysis was satisfied (less than 0.29%). Recoveries of quantified compounds ranged from 98.36 to 100.30%. This result indicates that the established HPLC method is very useful for the determination of a marker compound in C. lachryma-jobi var. ma-yuen roots extracts.

• Restorative Dentistry and Endodontics
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• v.27 no.3
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• pp.290-298
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• 2002

3차원적으로 잘 충전된 근관은 치근단 누출과 재감염을 방지하며, 조직이 잘 치유될 수 있는 생물학적 환경을 제공해준다. 이 때문에 근관계의 완전한 충전은 근관치료의 중요한 목표 중의 하나이다. 본 연구의 목적은 4가지 방법으로 근관충전 후 디지털 방사선 사진을 촬영하여 근관충전의 질을 평가하고 투명표본을 제작하여 색소침투범위를 측정함으로써, 근관충전방법에 따른 치근단부 폐쇄능을 비교 평가하고자 하는 것이다. 직선형의 단근관을 갖는 80개의 전치를 선택하여 ProFile$^{\circledR}$ 니켈-티타늄 회전식 기구를 사용하여 근관을 성형한 후 무작위로 20개씩 4군으로 나누었다. 사용된 근관충전법은 다음과 같다：MicroSeal$^{\circledR}$(Group A), Thermafil$^{\circledR}$(Group B), Continuous wave 충전법(Group C), 측방가압충전법(Group D), 각 군에서 10개 치아는 Sealapex를, 나머지 10개 치아는 AH26$^{\circledR}$을 충전용 시멘트로 사용하였다. 근관충전이 끝난 치아는 충전의 질과 길이를 평가하기 위해, 근원심과 협설방향으로 디지털 방사선 사진을 이용하여 촬영하였다. 각 치아의 치근단부 2mm를 제외한 나머지 부위는 두겹의 nail varnish를 바르고, 2% methlylene blue용액에 48시간동안 침잠시켰다. 흐르는 물에 깨끗이 세척한 후, 투명치아를 만들었다. 선상의 색소침투를 관찰하고 치관측 최대깊이를 입체현미경하에서 40배율로 평가하여 다음과 같은 결과를 얻었다. 1. 충전방법에 따른 근단부 폐쇄효과를 비교시, 실험군 모두 비교적 양호한 근단부 폐쇄효과를 보였고 통계학적으로 유의성이 없었다. 2. 충전용 시멘트에 따른 근단부 폐쇄효과를 비교시, AH26$^{\circledR}$을 사용한 군에서 Sealapex를 사용한 군보다 더 적은 색소침 투를 나타냈다(p<0.05). MicroSeal$^{\circledR}$을 이용한 실험 1군내에서 AH26$^{\circledR}$을 사용하였을 때 미세누출이 더 적었고(p<0.05), 다른 군내에서는 통계학적으로 유의성이 없었다. 3. 근단부 충전상태에 따른 미세누출 비교시, 저충전, 과충전과 색소침투간에는 상관관계가 없었다. 4.충전방법에 따른 근단부 충전상태 평가시, Thermafil$^{\circledR}$을 이용한 실험 2군에서 과충전이 많이 나타났다(p<0.05). 이상의 결과로, 기존의 측방가압법 및 여러 열가소성 충전법이 유사한 근단부 폐쇄효과를 나타낸 바, 방법에 따른 술자의 숙련도, 충전시간, 재근관치료의 편이성 등을 고려하여 근관충전방법을 선택하는 것이 합리적일 것이라고 사료된다.