• Title/Summary/Keyword: 약효

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A Study on Crop Group for Pesticide Efficacy and Crop Safety of Minor Crops (소면적 재배작물의 약효 및 안전성 그룹화 적용 연구)

  • Ahn, Chang-Hyun;Kim, Yong-Hun;Eom, Hoon-Sik;Lee, Gwang-Ha;Ryu, Gab-Hee
    • The Korean Journal of Pesticide Science
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    • v.18 no.4
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    • pp.364-375
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    • 2014
  • This study was carried out to investigate the pesticide efficacy and crop safety among different leafy vegetables applied with foliar spraying under greenhouse and to check extrapolating from some trial data to other minor crops. Leafy vegetables used in this study were: lettuce (Lactuca sativar), leaf broccoli (Brassica oleracea.), chicory (Cichorium intybus.), chinese cabbage (Brassica campestris subsp. napus var. pekinensis), radish (Raphanus sativus), rape (Brassica napus), crown daisy (Chrysanthemum coronarium), edible burdock (Arctium lappa), endive (Cichorium endivia) and mustard greens (Brassica jumcea). Based on the result of control efficacy, all crops were classified into the groups. The results showed the probabilities of extrapolating the control value data of minor crop within the same group. It would be possible to use the pesticides which are already been registered for similar crops to those crops have no registered pesticides.

Effects of Increasing Air Temperatures and CO2 Concentrations on Herbicide Efficacy of Acalypha australis and Phytotoxicity of Soybean Crops (대기온도와 CO2 농도 증가에 따른 우점잡초 깨풀의 제초제 약효 및 콩 약해 변화)

  • Hyo-Jin Lee;Hyun-Hwa Park;Ye-Geon Kim;Do-Jin Lee;Yong-In Kuk
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.68 no.3
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    • pp.121-133
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    • 2023
  • The purpose of this study was to improve weed management systems under varying carbon dioxide concentrations and temperatures by evaluating the growth of Acalypha australis and observing the efficacy of four foliar and four soil herbicides, as well as measuring phytotoxicity in soybean crops treated with these herbicides. In both growth chamber and greenhouse conditions, plant height and shoot fresh weight of Acalypha australis increased as temperature increased. The variable to maximum fluorescence ratio (Fv/Fm), relative electron transport rate (ETR), plant height, leaf area, and shoot fresh weight of Acalypha australis were higher at carbon dioxide concentrations of 800 ppm than at 400 ppm. The efficacy of a foliar herbicide, glufosinate, on Acalypha australis was lower at 30℃ than at 20℃ and 25℃ in the growth chamber condition and was also lower at 29℃ than at 21℃ and 25℃ in greenhouse conditions. In contrast, mecoprop efficacy on Acalypha australis was lower at 20℃ and 25℃ than at 30℃ in growth chamber conditions and lower at 21℃ and 25℃ than at 29℃ in greenhouse conditions. Glyphosate efficacy was lower at 21℃ than at 25℃ and 29℃ under greenhouse conditions. With soil herbicides, metolachlor and ethalfluraline, efficacies were higher at relatively high temperatures under both growth chamber and greenhouse conditions. However, in the case of linuron, the difference in efficacy was not observed under varying temperatures in both growth chamber and greenhouse conditions. When ¼ of the recommended glyphosate rates were applied to Acalypha australis, efficacy was lower under 800 ppm carbon dioxide concentrations than under 400 ppm. In contrast, when ¼ of the recommended rate of bentazone was applied to Acalypha australis, efficacy was higher under 800 ppm carbon dioxide concentrations than under 400 ppm. Despite application rates, glufosinate efficacy differed insignificantly under different carbon dioxide concentrations. When applied at ¼ of the recommended rate, the efficacy of ethalfuralin was higher under 800 ppm carbon dioxide concentrations than under 400 ppm. However, efficacies of other herbicides were not different despite varying carbon dioxide concentrations. Soybean phytotoxicity in crops treated with the recommended rate and twice the recommended rate of soil herbicides was not significantly different regardless of temperature and carbon dioxide concentrations. Overall, weed efficacy of some herbicides decreased in response to different temperatures and carbon dioxide concentrations. Therefore, new weed management methods are required to ensure high rates of weed control in conditions affected by climate change.

핵산 유도체들에 대한 in vitro 항바이러스 약효검색

  • 이종교
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.112-112
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    • 1993
  • 바이러스 치료제 개발을 위하여 합성된 핵산유도체 11개에 대한 in vitro 항바이러스 약효검색을 수행하였다. 검색대상 바이러스로서 외피보유 DNA 바이러스인 human herpesvirus에 속하는 herpes simplex virus type 1과 type 2에 대해서는 Vero 세포체계에서 3일 후 CPE 저해정도를 MTT 검색법으로 cytomegalovirus에 대해서는 HEL 세포체계에서 7일 후 Giemsa 염색법으로 약효를 측정하였다. 외피비보유 RNA 바이러스인 picornavirus에 속하는 poliovirus type 1과 type 3과 coxsackie B virus type 3에 대한 약효를 HeLa 세포체계에서 2일 후 CPE 저해정도를 MTT 검색법으로 측정하였다. 아울러 selectivity index를 구하기 위하여 Vero와 HeLa 세포에 대한 약물자체의 독성인 cytocidal effect를 MIT 검색법으로 측정하였다. 그 결과 항 herpesvirus 약효는 어떤 물질에서도 발견되지 않았으나 한 물질이 poliovirus type 1과 3에 대하여 selectivity index 10정도 (CC$_{60}$ 38 ug/ml, EC$_{50}$ 1-4 ug/ml)를 나타내었고 자세한 기작은 좀 더 조사할 필요가 있다.

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과학ㆍ기술ㆍ사회 - 의약분업과 대체조제

  • Kim, Yong-Ik
    • The Science & Technology
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    • v.32 no.8 s.363
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    • pp.22-23
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    • 1999
  • 의약분업이 의사회와 약사회의 협의로 2000년 7월부터 실시하게 되었다. 이번 합의안에는 '대체조제'를 전면 허용하고 있는데 여기서 문제되는 것은 '약효의 동등성'이다. 최초로 개발해 시판하는 오리지널 제품이 아닌 카피 제품들의 약효를 믿을 수 있는가. 이번 의약분업 실현을 계기로 이미 시판되고 있는 모든 카피 제품들을 재검정하여 약효가 떨어지는 제품은 과감히 정리하여 '약이 국민 건강을 지키는 진정한 약'으로 새롭게 탄생해야 하겠다.

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Application of Neo-PPS Fumigation to the Disinfection of the Silkworm Larvae, Bombyx mori(L.), for the Control of Silkworm Diseases(I) Effect of Neo-PPS Fumigation on the Virus Diseases (Neo-PPS 훈증에 의한 잠체 소독에 관한 연구(I) -누에 바이러스병에 대한 약효-)

  • 임종성;김근영
    • Journal of Sericultural and Entomological Science
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    • v.18 no.2
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    • pp.79-81
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    • 1976
  • Experiments on the disinfection of the silkworm larvae by the application of Neo-PPS fumigation have been carried out for the control of virus diseases. The results obtained are summarized as follows. The disinfection of 2, 4 and 6 hours'fumigation with Neo-PPS (para-formaldehyde) showed an outstanding effect on the inactivation of the both viruses, nuclear polyhedrosis virus and cytoplasmic polyhedrosis virus, without significance in the 2. 4. and 6 hours' treatment.

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Flumethasone 투여후의 수의임상 관찰

  • McCormick J.E.
    • Journal of the korean veterinary medical association
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    • v.27 no.5
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    • pp.288-290
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    • 1991
  • 개의 여러가지 질병상태에서 근복적인 치료나 보조적인 치료제로서의 flumethasone 투여는 아주 좋은 치료효과를 나타냈다. 우리가 병원에서 상용하는 flumethasone의 평균 투여량은 0.125$\~$0.5mg으로서 경구 또는 주사로 투여했다. 경구적으로 투여하는 주된 사용량은 1일 0.03125mg$\~$0.125mg이며 환축의 크기, 치유과정 그리고 병증의 심한 정도에 따라 양을 가감했다. 투여경로를 달리하여도 약효에 차이가 생기지는 않았다. flumethasone의 소염효과, 당신생효과 및 항독소적 치료효과에서 기존의 corticoids 투여시 나타나는 효과에 비해 정성적인 차이는 없었으나 실험실 결과와 병원에서 사용한 임상결과 flumethasone은 hydrocortisone보다 300$\~$400배 그리고 prednisone이나 prednisolone 보다는 60$\~$80배나 강한 약효를 발휘하는 것으로 나타났다. 임상적용에서 나타난 감동적인 효과에서 이러한 flumethasone의 약효에 대한 자료들이 입증되었다. 또한 치료된 동물들이 보여준 반응은 flumethasone의 약효 지속시간이 기존의 corticoids보다 더 긴 것으로 나타났다. 앞에서 언급했듯이 flumethasone 투여시는 전해질 불균형에 의해 유발되는 다음다갈증이나 다뇨증, 식욕촉진 등의 부작용이 전혀 나타나지 않았다. 이러한 flumethasone의 안전성은 기존의 corticoids로 비만동물이나 나이든 환축을 치료할때 자주 나타났던 부작용업이 장기간 치료할 수 있으므로 아주 중요하다.

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한방의학 면에서 본 오골계

  • 대한양계협회
    • KOREAN POULTRY JOURNAL
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    • v.12 no.3 s.125
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    • pp.50-51
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    • 1980
  • 오골계에 대하여는 이미 지상을 통하여 그 약효등이 널리 알려져 왔으며 천연기념물로 정하여 보호하고 있다. 오골계에 대한 일반의 관심이 높아지자 서울 한가운데에서 삼계탕을 오골계로 만들어 삼오골계탕이 대성업을 하고있다. 외지에 소개된 중국산 오골계에 대한 약효를 참고로 소개한다.

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Herbicidal Activity of Newly Rice Herbicide Tefuryltrione Mixture against Sulfonylurea Resistant Weeds in Korea (설포닐우레아계 제초제 저항성 논잡초에 대한 신규 제초제 Tefuryltrione 합제의 약효 및 선택성)

  • Park, Min-Sik;Kim, Se-Min;Park, Yong-Seog;Lee, Kun-Sik;Woo, Jung
    • Korean Journal of Weed Science
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    • v.32 no.2
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    • pp.133-138
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    • 2012
  • This study was conducted to investigate the herbicidal activity against resistant biotype on sulfonylurea (SU) herbicides such as Scirpus juncoides and Monochoria vaginalis at the glasshouse and paddy rice cultivation area. In order to investigate resistance breakability against SU-resistanted annual weeds, new rice herbicides containing tefuryltrione [p-hydrophenyl pyruvate dioxygenase (HPPD) inhibitor] were tested. In both lab test and field experiment, tefuryltrione mixture, 4-HPPD inhibitor had shown excellent efficacy with a bleaching on the leaves of resistant annual weeds at early time after treatment and showed excellent persistance. Especially, tefuryltrione mixture had shown excellent controlling effect on annual and perennial SU-resistant S. juncoides in the regional field experiment. In phytotoxicity test, this tefuryltrione mixture had shown good selectivity to common rice species.