• Food Science of Animal Resources
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• v.25 no.3
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• pp.316-321
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• 2005

A total of ninety six pigs ($L{\times}Y{\times}D$, 20.92(2.13kg average initial body weight) were used in a 16-week performance growth assay to determine the effect of supplemental medicinal plane (Artemisia, Acanthopanax and Garlic) on growth performance, IGF-1 of serum and carcass characteristics in finishing pigs. The dietary treatments were included 1) CON (basal diet; Control), 2) MP1 (basal diet added $0.02\%$ of medicinal plant mixtures), 3) MP2 (basal diet added $0.04\%$ of medicinal plant mixtures) and 4) MP3 (basal diet added $0.06\%$ of medicinal plant mixtures). Through entire experimental period, as medicinal plants mixture (MP) increased, there was a decrease (linear, P<0.08) in average daily feed intake and an increase (linear, P<0.02; quadratic, P<0.08) in gain/feed. The backfat thickness tended to decrease in pigs fed MP diet compared to pigs fed CON diet (linear, P<0.09; quadratic, P<0.01). Increasing medicinal plane mixture tended to increase in IGF-1 content in serum (linear, P<0.09). The hunter $a^{*}$ (redness) (linear, P<0.01) and $b^{*}$ (yellowness) (linear, P<0.02) values of longissimus muscle were affected by the dietary MP treatments. The color of longissimus muscle was higher in the dietary MP treatments than that of the muscle in the control diet (linear, P<0.03). In conclusion, the result obtained from this feeding triad suggest that the medicinal plants mixture supplementation below $0.06\%$ in diets for growing-finishing pigs can be improved growth performance, IGF-1 and meat quality.

• The Korean Journal of Food And Nutrition
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• v.16 no.4
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• pp.328-333
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• 2003

When the extract of the medicinal plants, Kaempferia galanga L., Zanthoxylum bungeanum, Eugenia caryophyllata, Foeniculum vulgare, was added to Naengmyeon broth with the concentration of 0.1% and 0.3% each, its effect during the preservation time of broth was investigated. pH of the extract-added broth was lower than control at the initial, but higher after 72 hours of preservation, which showed that when it added 0.1% and 0.3% of extract to the broth, pH of Kaempferia galanga L. was 4.92 and 5.08 respectively, whereas control was 4.60. Titratable acidity was lowered after 48 hours and also Kaempferia galanga L. showed the lowest acidity with 0.66 for adding 0.1% of its extract and 0.55 for 0.3% of adding, but control was 0.89 at the time of 90 hours of preservation, and then it showed to be lowered in the order of Zanthoxylum bungeanum, Eugenia caryophyllata and Foeniculum vuigare. Turbidity of each broth added the extracts of four of the medicinal plants was 7.5∼7.9 and 7.9∼8.2, respectively for 0.1% and 0.3% of concentration at the initial, but it began to lower and 90 hours later it was 8.8∼9.5 and 8.7∼9.0 respectively, whereas control was 10.8. Total viable cells(TVC) and coliform bacteria(CB) were increased with great at the 72 hours of preservation time, and Kaempferia galanga L. was the most effective, which when control was 4.8${\times}$10 CFU/ml at 72 hours, TVC was 1.7${\times}$10 CFU/ml for the addition of 0.1% of extract and 0.9${\times}$10 CFU/ml for 0.3%. CB was 3.2${\times}$10 CFU/ml for 0.1% and 1.7${\times}$10 CFU/ml for 0.3% respectively and 6.0 ${\times}$ 10 CFU/ml for control at the time of 72 hours, and it was lowered in the order of Zanthoxylum bungeanum, Eugenia caryophyllata and Foeniculum vulgare. Volatile basic nitrogen content detected that control was 2.67mg% at first, and then increased to 3.96mg% at 90 hours of preservation, but the broth added with the extract of Kaempferia galanga L. was 2.58mg% for 0.1% and 2.47mg% for 0.3% at the initial, and at 90 hours it was 3.64mg% and 3.33mg% respectively. The results of adding the extracts of four medicinal plants for the improvement of the preservation time of Naengmyeon broth, were that the most effective medicinal plant was Kaempferia galanga L. and the antimicrobial activity of the medicinal plant extracts for Naengmyeon broth was highly effective after 3 days of preservation time.

• Korean Journal of Plant Resources
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• v.34 no.1
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• pp.44-51
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• 2021

Centella asiatica (L.) Urban is a medicinal plant containing madecassic acid, triterpenoids and asiaticoside, and has a wound healing effect. However, since it grows only in some regions of Korea, it is necessary to breed stable varieties. In this study, it were analyzed for the growth characteristics, asiaticoside, anxiodant components and 2,2-diphenyl-1picryl hydrazyl (DPPH) radical scavening activity of C. asiatica collected from domestic natural habitat (Hapcheon, Gyeongnam). In the growth characteristics of each resource, CA9 and CA10 were superior in characteristics of aerial part and in dry weight. In asiaticoside content analysis, CA5 and CA3 were high with 53.96 mg/g and 52.40 mg/g, respectively. CA12 showed the possibility of development because the resource showed high in total flavonoid (7.3 mg/g), total polyphenol (10.64 mg/g) and DPPH activity (11.96 mg AAE/g) among other resources. However, it is necessary to select a resource suitable for each characteristic of C. asiatica and to study charateristics through additional resources collection since the excellent growth characteristics of the collected resources do not necessarily coincide with the content and antioxidant activities.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2020.08a
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• pp.98-98
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• 2020

본 연구의 목적은 약재로 사용되는 천궁 중 토천궁(Ligusricum chuanxing Hort.)에 대한 지역별 생육환경을 확인하고 이에 따른 지상부 및 지하부 생장과의 상관관계를 규명하여 토천궁의 적정 재배지역 확인 및 지속 가능한 안정적인 한약재 생산에 대한 기초자료로 사용함에 있다. 토천궁이 주로 재배되고 있는 봉화군, 영양군, 평창군과 더불어 기후변화에 의한 재배지 이동을 고려하여 고위도 지역인 인제군을 포함한 4지역의 재배지를 선정하였으며, 생육특성을 비롯 기상 및 토양환경을 분석하여 토천궁의 생육특성과의 상관관계를 분석하였다. 4지역의 재배지 중 지상부와 지하부의 전체적인 생육은 평창지역에서 유의적으로 높게 확인되었다. 그리고 생육특성과 기상환경과의 상관관계에서 대기 및 토양온도가 지상부의 전체높이, 줄기직경, 지하부의 생육특성과 P < 0.01수준에서 유의적인 음의 상관관계, 잎의 길이 및 너비와는 양의 상관관계를 보였다. 또한 일사량이 높아질수록 잎의 크기를 제외한 생육특성이 양의 상관관계를 나타냈는데 이는 대기 및 온도의 상승으로 인한 잎의 증발산율 상승과 일사량에 따른 잎의 광합성량의 차이에 의한 결과라 사료된다. 또한 토양특성과의 상관관계에서 OM과 N, P, K는 지상부의 전체 높이와 줄기 직경을 비롯한 지하부의 생육특성과 음의 상관관계를 보였는데 근권의 토양시료를 사용하여 분석한 것이라 실질적으로 토천궁의 생육에 필요한 토양의 성분이 OM과 N, P, K이며, 토천궁에 의해 흡수되었다고 판단되는데 생육이 가장 우수했던 평창지역 토양 내 OM(1.69%)과 N(0.09%), P(897.72mg/kg), K(0.21cmol⁺/kg)의 수치가 타 지역 대비 상대적으로 낮게 측정된 결과가 본 실험에서 확인된 생육에 대한 OM, N, P, K의 함량과 부의 상관관계를 지지하며, 본 연구의 결과는 향후 토천궁의 재배지 선정 및 재배기술 정립에 활용할수 있을 것이라 사료된다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2020.08a
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• pp.99-99
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• 2020

참당귀(Angelica gigas Nakai)는 중국의 동북부지역, 일본 및 한반도 전역에 자생하고 있으며, 예로부터 보혈, 활혈지통, 윤장등의 효능으로 심신혈허, 월경불순, 통경경폐 등의 병증에 주로 사용되었고, 8월부터 뿌리가 급격히 비대하여 10월 말에서 11월 초에 수확을 한다. 본 연구는 참당귀의 주산지인 봉화, 평창을 비롯한 영양, 인제 등 4지역을 선정하여 미세기상장비를 설치 및 토양의 이화학성 분석을 통해 지역별 생육환경을 측정하였고, 또한 참당귀의 생육특성을 조사하였다. 그 결과 5월에서 10월까지 평균 대기온도와 일사량은 인제지역에서 다른지역에 비해 비교적 높은 경향을 나타냈다. 또한 토양온도는 5월에서 8월까지는 영양지역이, 9월과 10월은 봉화지역이 다른지역에 비해 비교적 높은 것으로 조사되었다. 지역별 토양 성분의 이화학적 특성은 봉화지역이 유기물(5.17%), 전질소(0.19%), 유효인산(2187.76mg/kg), 칼륨(1.53cmol⁺/kg)의 함량이 다른 지역에 비해 높은 경향으로 확인되었고, 인제지역이 칼슘(12.63 cmol⁺/kg), 마그네슘(3.7cmol⁺/kg)등 미량원소의 함량이 높은 것으로 분석되었다. pH는 지역별 차이가 확인되지 않았으며, 영양지역의 토성이 사질식양토로 배수성의 차이는 확인되었다. 이에 따른 참당귀의 생육특성은 초장과 줄기직경은 영양지역에서 각각 70.95cm와 35.72mm로 가장 높게 측정되었으며, 잎 길이및 너비는 평창지역에서 각각 42.84cm, 52.39cm로 가장 높게 측정되었다. 뿌리직경은 영양에서 50.49mm, 뿌리길이는 봉화에서 38.05cm, 생중량은 평창에서 328.23g으로 다른지역에 비해 높은 경향을 나타냈다. 상기 결과를 바탕 재배환경과 생장량간의 상관관계를 분석하였다. 재배환경 중 대기 및 토양온도, 대기 습도는 실험이 수행되어진 전 지역에서 이상고온이나 저온과 같은 특이점 없이 비슷한 양상으로 측정되었고, 이에 따라 참당귀생장에 대해 유의한 상관관계가 분석되지 않았다. 토양습도는 지상부(초장, 줄기직경, 잎길이, 잎너비)의 생육과 음의 상관관계에 있다고 사료되나 유의성이 검증되지 않았다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.1
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• pp.83-89
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• 2012

Medicinal herbs have been shown to have protective functions for skin and hair. We investigated the effects of complex of soluble ${\beta}$-cyclodextrin and phytochemicals on the functions of skin and hair. In previous report, we evaluated the safety of supramolecules and found their anti-microbial effects and anti-fungal effect against Gram (+) and Malassezia furfur which is known to cause dandruff. Here we present that functional supramolecules-containing cream promotes the biological skin activity by inducing the collagen formation. And treatment of supramolecules-containing hair tonic increased the rate of hair growth of mouse. Taken together, supramolecular cosmetic compounds containing water insoluble phytochemicals and water soluble ${\beta}$-cyclodextrin exhibit the potential ability for hair growth promotion and delaying the aging of skin.

• Journal of the Korean Applied Science and Technology
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• v.30 no.1
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• pp.173-182
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• 2013

Atopic dermatitis is a chronic, relapsing inflammatory skin disease associated with dysfunction of skin barrier and cutaneous hyper-reactivity to environmental triggers. In the previous study, cytotoxicity, antioxidant, anti-inflammatory and anti-allergic activities were investigated for various herbal extracts such as Aloe vera L. (AV), Viola mandshurica W. Becker (VM), Punica granatum L. (PG), and Dendrobium nobile L. (DN) in order to develop effective therapeutic herbal extracts for atopic dermatitis, In this study, anti-inflammatory activities of these herb extracts in lipopolysaccharide (LPS)-induced macrophage RAW264.7 cells were further examined to find the underlying molecular mechanisms. The RT-PCR (reverse transcription polymerase chain reaction) analysis showed that PG, DN and AV inhibited effectively the gene expression of pro-inflammatory cytokines IL-6 and IL-$1{\beta}$ in LPS-stimulated macrophages, while VM did not. The transfection and luciferase analysis exhibited that all herbal extracts hindered the activation of transcription nuclear factor kappa B (NF-${\kappa}B$). The western blot analysis indicated that AV blocked the activation of only JNK MAP (c-Jun N-terminal kinase mitogen-activated protein) kinase not p38 MAP kinase, while VM, PG and DN did not show the activation of both JNK and p38 MAP kinases. These results suggest that AV, VM, PG, and DN have anti-inflammatory activities and thus have the potential to reduce and alleviate the symptoms of atopic dermatitis.

• Korean Journal of Weed Science
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• v.9 no.2
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• pp.154-167
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• 1989

This study was conducted to determine the influence of various extracts from 21 medicinal plants including Bupleurm falcatum on the germination and growth of Lactuca sativa, Oryza native and E. crus-galli var. crus-galli, and the amount of their phenolic acids, fatty acids and organic acids, Water extract(5%) of all the medicinal plants, particularly Acorus gramineus, Cnidium officinale, Aconitum carmicheali, Bulpeurum falcatum, Zingiber officinale, Angelica gigas and Curcuma zeodaria inhibited over 90% of the lettuce seed germination and growth, indicating that medicinal plants contained the biologically active substances. The highest amount of phenolic compounds was observed in Prunus crmenica var, ansu(30.6013mg/g) followed by Aconitum ciliare(29.1008mg/g) and Cnidium officienale(27.2943mg/g) which inhibited markedly the germination of testing plants, showing the close relation of phenolic compounds to inhibitory effects. Cnidium officinale contained the highest amount of fatty acids(24.10mg/g) and organic acids(21.04mg/g) which may be partly related to inhibitory effects.

• Food Science and Preservation
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• v.19 no.5
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• pp.744-750
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• 2012

In this study, the optimal conditions for phenolic-compound extraction from medicinal plants were found to be 24 h and about 50% ethanol. The electron-donating scavenging activities (DPPH), ABTS radical-cation decolorization (ABTS), antioxidant protection factor (PF), and thiobarbituric acid reaction substance (TBAR) were measured to determine the antioxidant activities of the extracts of Sanguisorba officinalis Linn., Citrus unshiu Markovich, Melia azedarach L., Asparagus cochinchinensis Merr., Citrus unshiu S., Polygonum aviculare L., and Leonurus sibiricus L. The total phenolic contents of the extracts of medical plants were determined to be 0.45-3.00 mg/g in the water extracts and 0.33-3.15 mg/g in the 50% ethanol extracts. The electron-donating abilities (EDA) of the water and ethanol extracts were both above 85% at the $50{\mu}g/ml$ concentration. The ABTS radical-cation decolorization was above 80% at the $100{\mu}g/ml$ concentration in all the extracts of various medicinal plants. The antioxidant protection factor (PF) of the Melia azedarach L. extracts was found to be $1.65{\pm}0.40$ PF in the water extracts at the $100{\mu}g/ml$ concentration, and was higher than those of the other medicinal-plant extracts. The TBAR inhibition rates of all the medicinal-plant extracts, except Asparagus cochinchinensis Merr., were above 85% at the $100{\mu}g/ml$ concentration. These results confirmed that the various oriental medicinal plants (Sanguisorba officinalis Linn., Citrus unshiu Markovich, Melia azedarach L., Asparagus cochinchinensis Merr., Citrus unshiu S., Polygonum aviculare L., and Leonurus sibiricus L.) that were included in this study are useful functional-food sources.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.8
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• pp.1136-1142
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• 2005

To develop new anti-aging foods or cosmetics by using antioxidants, SOD activator and elastase inhibitor, both potent anti-aging substances, were screened from various extracts of medicinal Plants and its optimal extraction conditions were investigated. Antioxidant activity has showed the highest in methanol extracts of Prunus persica (seed; 98.0$\%$). Methanol extracts of Morus alba (leave; 41.0$\%$) showed the highest elastase inhibitory activity while Lycium chinense (fruit; 197$\%$) showed the highest activation effect in SOD activity. The Prunus persica extract that exhibited the highest activity was extracted by treatment of Prunus persica powder with methanol at 40$^{\circ}C$ for 18 h and the SOD activity was maximum with extract from Lycium chinense extracted with deionized water at 30$^{\circ}C$ for 12 h. Elastase inhibitory activity of Morus alba was maximally extracted when it was treated with 70$\%$ methanol at 50$^{\circ}C$ for 12 h.