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http://dx.doi.org/10.3746/jkfn.2005.34.8.1136

Screening and Extraction Condition of Antiaging Bioactive Substances from Medicinal Plants  

Yu, Hyung-Eun (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Dela Paz, Leaniza Michella M. (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Bae, Young-Joo (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Lee, Dae-Hyoung (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Park, Jong-Sang (Central Research Institute, Pan Korea Co.)
Kwak, Hahn-Shik (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Kim, Ha-Kun (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Lee, Jong-Soo (Dept. of Life Science and Genetic Engineering, Paichai Univerity)
Publication Information
Journal of the Korean Society of Food Science and Nutrition / v.34, no.8, 2005 , pp. 1136-1142 More about this Journal
Abstract
To develop new anti-aging foods or cosmetics by using antioxidants, SOD activator and elastase inhibitor, both potent anti-aging substances, were screened from various extracts of medicinal Plants and its optimal extraction conditions were investigated. Antioxidant activity has showed the highest in methanol extracts of Prunus persica (seed; 98.0$\%$). Methanol extracts of Morus alba (leave; 41.0$\%$) showed the highest elastase inhibitory activity while Lycium chinense (fruit; 197$\%$) showed the highest activation effect in SOD activity. The Prunus persica extract that exhibited the highest activity was extracted by treatment of Prunus persica powder with methanol at 40$^{\circ}C$ for 18 h and the SOD activity was maximum with extract from Lycium chinense extracted with deionized water at 30$^{\circ}C$ for 12 h. Elastase inhibitory activity of Morus alba was maximally extracted when it was treated with 70$\%$ methanol at 50$^{\circ}C$ for 12 h.
Keywords
anti-aging bioactive substances; extracts; medicinal plants;
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