• 대한치과보철학회지
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• 제53권1호
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• pp.74-80
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• 2015

구강암의 발생 시, 구순의 결손과 방사선치료에 의한 치주조직과 치경부우식증 등의 문제가 발생할 수 있다. ADI (Association of dental implantology)에 의하면 상 하악골에 대한 방사선치료가 최근에 시행되었을 경우 임플란트를 식립하는 것은 상대적 비적응증이 된다. 대부분의 경우 임플란트를 이용한 보철물의 제작이 어렵고 의치를 사용한 수복이 이루어지게 된다. 특히, 구강암 수술로 인한 구순결손은 의치의 유지에 심각한 영향을 주게 된다. 본 증례는 상순암을 가진 환자로 일차적으로 절제술을 시행하고, 이차적으로 방사선 치료가 정기적으로 이루어진 결과, 환자의 상악 치아들은 순차적으로 자연 발치되었고, 하악은 매우 불량한 치주상태를 나타내었다. 상악은 총의치에 의치접착제를 적용하여 구순결손에 의한 의치의 유지력 저하를 극복하였고, 하악에서는friction pin을 이용한 하악이중관의치가 2년 동안 성공적으로 사용되었다.

• 대한상부위장관⦁헬리코박터학회지
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• 제18권3호
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• pp.150-156
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• 2018

Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which "precision" is important because the current modern medicine starts from "trial and error," and "one does not fit all". Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.

• 대한간호학회지
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• 제30권4호
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• pp.857-868
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• 2000

The purpose of the present study is to identify the mediation effect of hope between fatigue and psychosocial adjustment in women with breast cancer. The framework for this study was guided by concepts and propositions derived from the theoretical and empirical literature on fatigue, hope and adjustment. The design of this study is a descriptive correlation study using a cross-sectional design. One hundred and twenty two outpatients with early breast cancer, receiving post-surgical radiation therapy or chemotherapy, were selected from three major medical centers in Seoul, Korea. A packet including PABCF (Psychosoical Adjustment to Breast Cancer Factor), revised RPFS (Revised Piper Fatigue Scale), HHI (Herth Hope Index), and self-addressed return envelope was given to the participants at seven to eight weeks post surgery. The questionnaires were to be completed at home and returned to the researcher by mail. The obtained data were analyzed using three regression equations guided by Baron and Kenny (1986); first, hope was regressed on fatigue; second, psychosocial adjustment was regressed on fatigue; and third, psychosocial adjustment was regressed on fatigue and hope, simultaneously. In the first equation, fatigue explained 4% of the variance in hope. In the second equation, fatigue explained 47% of the variance in psychosocial adjustment. In the last equation, hope and fatigue significantly explained the variance in psychosocial adjustment. Therefore, all conditions for the test of mediation effect of hope were satisfied. For the test of the mediation effect, the beta coefficients of fatigue on psychosocial adjustment on the second and third regression equations were compared. The beta coefficients were decreased from .69 (p < .001) on the second regression equation to .63 (p < .001) on the third regression equation. Thus, the hypothesis of this study was supported. As a result of this study, the negative Influence of fatigue on psychosocial adjustment is dampened through the mediator effect of hope in women with breast cancer. Therefore, when planning care for the adverse effect of fatigue on psychosocial adjustment, oncology nurses should consider hope as a mediator between fatigue and psychosocial adjustment to breast cancer.

• Child Health Nursing Research
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• 제24권1호
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• pp.78-90
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• 2018

Purpose: The purpose of this study was to evaluate measurement properties of self-report questionnaires measuring the social adjustment for youth after treatment of childhood cancer. Methods: Social adjustment measurement tools were identified through a two-stage systematic review. First, we searched for articles using self-report questionnaires to measure the social adjustment of youth after the treatment of childhood cancer. The appropriate tools were listed and categorized. Second, using methodological filters, we searched 5 electronic databases for articles examining the measurement properties of the tools when used with youth after the treatment of childhood cancer. The quality of these papers was then evaluated using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist. Results: Eight tools were frequently used to measure social adjustment. Eight studies investigated the measurement properties of 4 of these tools. The PedsQL 4.0 and MMQL-AF had moderate to strong evidence in some domains, but the rest of the domains had a lack of evidence. The SF-36 and KIDSCREEN-27 were validated for only a few areas. Conclusion: We found a lack of evidence regarding the measurement properties of these tools. More research is required on the measurement properties of tools for use in this population.

• 대한간호학회지
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• 제41권2호
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• pp.225-235
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• 2011

Purpose: To describe psychosocial adjustment of low-income Koreans who have cancer. Methods: Data were collected during 2008 using individual in-depth interviews with 18 Korean people with cancer. The income status of the participants was low, 11 were recipients of the National Basic Livelihood Protection program. Mean age was 58.3 yr and 11 were female. Five participants had stomach cancer, five, colorectal cancer, and four, breast cancer. Data were analyzed using grounded theory methodology. Results: The core category emerged as 'bearing up alone with double suffering'. 'Poverty and cancer: A double suffering' emerged as a causal condition. The adjustment process consisted of three stages: 'forming a treatment will to live', 'practicing for the cure', and 'restructuring self and repaying favors'. Each stage indicated action-interaction strategies which were employed to bear up alone with double suffering during the illness process. Self-reflection, parental responsibility, and support from the public sector played important roles in overcoming the double suffering. Two types of consequences were identified: Transcended life and strained life suppressed by poverty and cancer. Conclusion: The results provide insights into the psychosocial adjustment process for low income Korean with cancer and can be used in developing and implementing efficient home-care services for these people.

• 종양간호연구
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• 제12권4호
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• pp.289-296
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• 2012

Purpose: The purposes of this study were to find the levels of distress and quality of life of breast cancer survivors in Korea and to identify relationship between distress and quality of life. Methods: The data were collected from 122 breast cancer survivors in 2009. To measure the distress and quality of life, the 'Distress Thermometer and Problem List' and the 'Functional Assessment Cancer Therapy-Breast' were used respectively. Results: The mean score of distress was 4.77 (${\pm}2.35$) and 63.1% of the subjects reported a distress score of 4 or more, indicating a clinically significant level of distress. Among these, the most frequently reported problem area was emotion, followed by family. The mean score of the quality of life was 88.22 (${\pm}18.41$), signifying 6.13 out of 10. The levels of distress and the quality of life were negatively correlated (r=-.38, p<.001). Conclusion: The results of the study indicate that distress is prevalent in Korean breast cancer survivors and the distress is related negatively with their quality of life. Thus oncology professionals continuously need to assess distress of breast cancer survivors and to provide appropriate psychosocial interventions to improve their quality of life.

• Journal of Hospice and Palliative Care
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• 제11권2호
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• pp.106-110
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• 2008

완화적 진정은 임종이 임박한 불응성 증상을 가진 환자들에게 고려될 수 있는 치료이지만 부적절한 진정으로 인한 윤리적인 문제가 쟁점이 된다. 본 증례는 수차례항암화학요법과 완화적 방사선 치료에도 불구하고 진행되는 다발성 뼈 전이를 동반한 전이성 위암을 가진 50세 남자에게 완화적 진정을 시행했던 예를 권고안에 비추어 후향적 검토하였다. 환자는 표준적인 통증경감치료에 불응성으로 판단되었고 환자의 의사결정능력 부족으로 환자보호자에게 완화적 진정에 대한 치료 목적 및 예견되는 부작용을 설명한 후 midazolam으로 완화적 진정을 시작하였다. 본 증례에 통하여 완화적 진정의 적응, 완화적 진정의 시작 전 의사 결정, 완화적 진정 시작, 완화적 진정 시작 후의 돌봄에 대한 토의를 하였고 국내실정을 반영한 권고안 마련을 제의하는 바이다.

• 건강소식
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• 제26권4호통권281호
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• pp.6-13
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• 2002

우리 몸은 적절한 운동을 함으로써 각각의 기능이 정상으로 적응하도록 되어있으며 적절한 운동을 하지 않으면 신체의 기능은 점점 약화되어 건강에 나쁜 영향을 주게 된다. 우리 주위의 많은 사람들은 이러한 사실을 알고 있어도, 시간이 없다는 핑계로, 다른 할 일이 많다는 핑계로 운동 부족을 자초하고 있다. 우리나라의 사망원인 순위를 보면 위기 암(악성신생물), 위가 뇌혈관 질환, 3위가 심장질환으로 식생활, 운동부족 등 잘못된 생활습관이나 스트레스등으로 인한 만성질환이다. 특히 운동부족은 심장병, 암, 당뇨병, 근골격계 질환(골다공증) 등의 위험요인이 되는데 운동부족과 밀접한 관계가 있는 허혈성 심질환의 경우 사망률이 1985년 인구 10만명당 3.8명에서 2000년 21.5명으로 5배 이상 증가하였으며 당뇨병의 경우 1985년 인구 10만명당 6.8명에서 2000년 22.6명으로 3배 이상 증가하였나(통계청, 200년 조사), 우리나라 성인들의 운동 실천율은 매우 낮은 편으로 규칙적으로 운동하는 사람의 비율이 0.8%에 머물러 운동부족의 심각성을 보여주고 있다(한국보건사회연구원 1998) 세계보건기구(WHO)와 보건복지부는 2002년 4월 7일 세계 보건의 날을 맞아 ‘Move for health'라는 구호로 운동의 중요성 및 생활 속의 활기찬 움직임에 대한 중요성을 일깨우기 위해 보건의 날 올해의 주제로 선정하였다. 4월의 이달의 건강 길라잡이에서는 생활 속에서 쉽게 실천할 수 있는 운동, 나에게 맞는 운동에 대하여 알아본다.

• 대한간호학회지
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• 제33권2호
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• pp.293-300
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• 2003

Purpose: The purpose of this study was to describe health problems and psychosocial adaptation in children with cancer and to determine the relationship between these two variables. Method: The data were collected from parents of 61 children with cancer, aged 4-11 years at one university hospital in Seoul. The instruments for this study were the Korea Child Behavior Check List (KCBCL) and a physical symptom checklist developed by the researchers. Result: The major health problems were coughing, sleeping disturbances, fatigue and weakness. The total behavior problem score for children in the cancer group was higher than the score for those in the norm group. The scores on the scales for withdrawal, somatic complaints, social immaturity, and internalizing problems were higher in the children with cancer compared to normative findings. Scores on social and school competence in the cancer group were lower than the norms for healthy children. The relationship between health problems and psychosocial adaptation was significant in the subscales of withdrawal, anxiety/depression, internalizing problems and social involvement in the off therapy group. Conclusions: This study shows the various areas that need further study in caring for children with cancer.

• 여성건강간호학회지
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• 제21권3호
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• pp.216-231
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• 2015

Purpose: The purpose of this study is to provide the basic data to develop the effective nursing intervention for the parent who have children with cancer by acquiring the deeper understanding of the mothers' adjustment of caring for their children with cancer. Methods: The ethnographic research method was used to find out the pattern of caring adjustment in Korean cultural context. Informants consisted of 12 mothers who were caring for their children with cancer. The data were collected using in-depth interviews, participant observation, and telephone interviews by maximum variation purposive sampling. The data were analyzed following Spradley's methodology. Results: The mothers' caring adjustment were organized into one cultural theme, four categories, and twelve properties. The cultural theme was 'standing alone as a mother with sin'. The four categories were 'blaming for falling illness', 'overcoming with motherhood', 'desperate struggling with side effects', and 'establishing new network as a dependent'. Conclusion: For the mothers who are caring children with cancer, the supportive nursing intervention based on the deeper understanding of mothers' pattern of caring adjustment for their children and centered on facilitating effective adjustment in each cultural context especially from the very early stage of caring in the hospital ward is extremely required.