• Title/Summary/Keyword: 암발생귀속위험

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Radiation dose and Lifetime Attributable Risk of Cancer Estimates in 64-slice Multidetector Computed Tomography (64-절편 다행검출 CT 검사에서의 환자선량과 암 발생의 Lifetime Attributable Risk(LAR) 평가)

  • Kang, Yeong-Han;Park, Jong-Sam
    • The Journal of the Korea Contents Association
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    • v.11 no.4
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    • pp.244-252
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    • 2011
  • This study was to estimate the radiation dose associated with 64-slice multidetector CT(MDCT) in clinical practice and quantify the potential cancer risk associated with these examinations. Lifetime attributable risks(LAR) were estimated with models developed in the national Academies' Biological Effects of Ionizing Radiation VII report. Mean effective dose were 1.48mSv in Brain axial scan, 7.66mSv in chest routine contrast, 12.17mSv in coronary angiogram, 24.52mSv in Dynamic abdomen scan. LAR estimates for brain routine varied from 1 in 7463 for man to 1 in 4926 for women. In chest routine with contrast, LAR varied from 1 in 1449 for men to 1 in 952. LAR of Abdomen dynamic CT varied from 1 in 453 for men to 1 in 298 for women. So, 64-slice MDCT scan is associated with non-negligible LAR of cancer. Doses can be reduced by careful attention to scanning protocol.

Radiation Dose and Estimate of Lifetime Attributable Risk of Cancer from Coronary Angiography and Percutaneous Coronary Intervention (관상동맥조영술과 경피적관상동맥중재술에서 환자 선량과 암 발생 생애귀속위험 평가)

  • Kang, Yeong-Han;Kim, Bu-Sun;Park, Jong-Sam
    • Journal of radiological science and technology
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    • v.33 no.3
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    • pp.213-221
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    • 2010
  • The Purpose of this study was to determine the effective dose to an average patient from Coronary Angiography (CA) and Percutaneous Coronary Intervention (PCI). And to estimate the lifetime attributable risk (LAR) of cancer associated with radiation exposure from CA and PCI. The dose-area product (DAP) values to the patient were recorded from 60 CA and 58 PCI. A Monte Carlo based program PCXMC was used to calculate the effective dose from DAP values for each patient. Lifetime attributable risks were estimated with models developed in the National Academies' Biological Effects of Ionizing Radiation VII report. The mean DAP values was $53.76\;Gy{\cdot}cm^2$ for CA and $165.82\;Gy{\cdot}cm^2$ for PCI. Mean effective dose were 1.28 mSv in CA, 3.94 mSv in PCI. Results of Calculate organ dose, lung doses was 2.17 mSv in CA and 6.71 mSv in PCI. Female breast doses was 5.45 mSv in CA and 16.82 mSv in PCI. LAR estimates for CA varied from 1 in 1,508 for man to 1 in 1,357 for women. In PCI procedure varied from 1 in 553 for man to 1 in 482 for women. DAP can be used as the dose indicator to calculate the organ dose and effective dose of patient based on Monte Carlo simulation. These dose estimates derived from our simulation models suggest that CA and PCI are associated with a nonnegligible LAR of cancer. This risk varies markedly and is considerably greater for women, PCI than for man, CA.

Comparison of Radiation Doses between 64-slice Single Source and 128-slice Dual Source CT Coronary Angiography in patient (64-slice single source CT와 128-slice dual source CT를 이용한 관상동맥 조영 검사 시 환자선량 비교)

  • Kang, Yeong-Han
    • Journal of the Korean Society of Radiology
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    • v.6 no.2
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    • pp.129-136
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    • 2012
  • The purpose of this study was to estimate radiation doses from 64-slice single source Computed Tomography(SSCT) coronary angiography(CA) and 128-slice dual source Computed Tomography(DSCT). With SSCT CA, the effective dose averaged approximately 13.86 mSv when two dose modulation was not. The mean effective dose for DSCT CA with retrospectively gated helical(RGH) technique was 11.87 mSv, when prospective ECG gating transverse(PGT) without dose modulation technique was 5.61 mSv. The one with dose modulation in PGT technique and flash mode were 3.04 mSv and flash mode was 0.98 mSv respectively. The lifetime attributable risk(LAR) of cancer incidence from SSCT RGH mode averaged approximately 1 for 1,176, and DSCT averaged 1 for 1,960(RGH mode), 1 for 3,030(PGT without modulation), 1 for 5,882(PGT with modulation). Because of CTCA is associated with non-negligible risk of cancer. Doses can be reduced by application PGT, FLASH than RGH using DSCT.