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http://dx.doi.org/10.5392/JKCA.2011.11.4.244

Radiation dose and Lifetime Attributable Risk of Cancer Estimates in 64-slice Multidetector Computed Tomography  

Kang, Yeong-Han (대구가톨릭대학교병원 영상의학과)
Park, Jong-Sam (대구보건대학 방사선과)
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Abstract
This study was to estimate the radiation dose associated with 64-slice multidetector CT(MDCT) in clinical practice and quantify the potential cancer risk associated with these examinations. Lifetime attributable risks(LAR) were estimated with models developed in the national Academies' Biological Effects of Ionizing Radiation VII report. Mean effective dose were 1.48mSv in Brain axial scan, 7.66mSv in chest routine contrast, 12.17mSv in coronary angiogram, 24.52mSv in Dynamic abdomen scan. LAR estimates for brain routine varied from 1 in 7463 for man to 1 in 4926 for women. In chest routine with contrast, LAR varied from 1 in 1449 for men to 1 in 952. LAR of Abdomen dynamic CT varied from 1 in 453 for men to 1 in 298 for women. So, 64-slice MDCT scan is associated with non-negligible LAR of cancer. Doses can be reduced by careful attention to scanning protocol.
Keywords
64-slice Multidetector CT; Dose Length Product; Effective dose; Lifetime Attributable Risk;
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1 보건복지가족부, 식품의약품안전평가원, 대한영상의학회, 대한방사선사협회, CT 엑스선검사에서의 환자선량 권고량 가이드라인, 방사선안전관리시리즈 No.19, 2009.
2 The Royal College of Radiologists, "Good Practice Guide for Clinical Radiologists," Royal College of Radiologists, London, 1999.
3 FDA, "Nationwide Evaluation of X-ray Trends(NEXT) Computed Tomography Dataset," 2000. http://www.fda.gov/cdrh/ radhlth/next.html
4 의료피폭가이드라인위원회, 의료피폭의 가이드라인, 사단법인 일본방사선기사회, 2000.
5 A. J. Einstein, M. J. Henzlova, and S. Rajagopalan, "Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography," JAMA, Vol.298, No.3, pp.317-323, 2007.   DOI   ScienceOn
6 J. Andrew, Javier Sanz, and D. Santo, "Radiation dose and cancer risk estimates in 16-slice computed tomography coronary angiography," J Nucl Cardiol, Vol.15, No.2, pp.232-240, 2008.   DOI   ScienceOn
7 김문찬, "64 채널 Multi-Detector Computed Tomography를 이용한 관상동맥검사의 선량 : 검사 프로토콜 다변화에 따른 환자선량 감소", 방사선기술과학, 제32권, 제3호, pp.299-306, 2009.   과학기술학회마을
8 ICRP, "Managing Patient Dose in Multi-Detector Computed Tomography," ICRP publication 102, 2007.
9 G. Bongartz, S. J. Golding, A. G Jurik, M. Leonardi, EvP van Meerten, and J Geleijns, "European guidelines on quality criteria for computed tomography," EUR 16262, 2000. http://www.drs.dk/guidelines/ct/quality
10 National research council of the National academies, "Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII-Phase 2," Division on Earth and Life Studies, Board on Radiation Effects Research, Washington, DC: National Academy Press; 2005.
11 L. F. Rogers, "Radiation Exposure in CT: Why so high?," AJR, Vol.177, No.2, pp.269-277, 2001.
12 European Atomic Energy Community, NEW Euratom Directive 43, 1997.
13 European Commission, European guidelines on quality criteria for computed tomography, Report EUR 16262, Office for Official Publications of the European Communities, Luxembourg 1999.
14 J. M. Boone, "The trouble with $CTDI_{100}$", Med Phys, Vol.34, No.4, pp.1364-1371, 2007.   DOI   ScienceOn
15 건강보험심사평가원, 건강보험통계연보, 2006.
16 D. J. Brenner, C. H. McCollough, and G. O. Colin, "It is time to retire the computed tomography dose index(CTDI) for CT quality assurance and dose optimization. For the proposition," Med Phys, Vol.33, No.5, pp.1189-1191, 2006.   DOI   ScienceOn
17 R. L. Dixon, "Restructuring CT dosimetry-A realistic strategy for the future. Requiem for the pencil chamber," Med Phys, Vol.33, No.10, pp.3973-3976, 2006.   DOI   ScienceOn
18 NRPB, "Doses from Computed Tomography (CT) Examinations in the U.K. 2003 Review," NRPB, UK, 2003.
19 S. Diederich and H. Lenzen, "Radiation exposure associated with imaging of the chest: comparison of different radiographic and computed tomography techniques," Cancer, Vol.89, No.11, pp.2457-2460, 2000.   DOI   ScienceOn
20 김문찬, TEXTBOOK of Computed Tomography, 청구문화사, pp.608-622, 2005.
21 E. S. Amis, P. F. Butler, and K. E. Applegate, "American college of radiology white paper on radiation dose in medicine," J Am Coll Radiol, Vol.4, No.5, pp.272-284, 2007.   DOI   ScienceOn
22 D. J. Brenner and E. J. Hall, "Computed tomography: an increasing source of radiation exposure," N Engl J Med, Vol.357, No.22, pp.2277-2284, 2007.   DOI   ScienceOn
23 R. Smith-Bindman, J. Lipson, and R. Marcus, "Radiation with common computed tomography examinations and the associated lifetime attributable risk of cancer," Arch Intern Med, Vol.169, No.22, pp.2078-2086, 2009.   DOI   ScienceOn
24 임청환, 조정근, 이만구, "전산화단층촬영 검사의 방사선 선량에 관한 연구", 방사선기술과학, 제30권, 제4호, pp.381-389, 2007.   과학기술학회마을
25 R. Fazel, H. M. Krumholz, and Y. Wang, "Exposure to low-dose ionizing radiation from medical imaging procedures," N Engl J Med, Vol.361, No.9, pp.849-857, 2009.   DOI   ScienceOn
26 Berrington de Gonzalez A, Mahesh M, Kim KP, and et al. "Projected cancer risks from computed tomographic scans performed in the United States in 2007," Arch Intern Med, Vol.169, No.22, pp.2071-2077, 2009.   DOI   ScienceOn