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Radiation Dose and Estimate of Lifetime Attributable Risk of Cancer from Coronary Angiography and Percutaneous Coronary Intervention  

Kang, Yeong-Han (Department of Diagnostic Radiology, Daegu Catholic University Hospital)
Kim, Bu-Sun (Department of Radiologic Technology, Daegu Health College)
Park, Jong-Sam (Department of Radiologic Technology, Daegu Health College)
Publication Information
Journal of radiological science and technology / v.33, no.3, 2010 , pp. 213-221 More about this Journal
Abstract
The Purpose of this study was to determine the effective dose to an average patient from Coronary Angiography (CA) and Percutaneous Coronary Intervention (PCI). And to estimate the lifetime attributable risk (LAR) of cancer associated with radiation exposure from CA and PCI. The dose-area product (DAP) values to the patient were recorded from 60 CA and 58 PCI. A Monte Carlo based program PCXMC was used to calculate the effective dose from DAP values for each patient. Lifetime attributable risks were estimated with models developed in the National Academies' Biological Effects of Ionizing Radiation VII report. The mean DAP values was $53.76\;Gy{\cdot}cm^2$ for CA and $165.82\;Gy{\cdot}cm^2$ for PCI. Mean effective dose were 1.28 mSv in CA, 3.94 mSv in PCI. Results of Calculate organ dose, lung doses was 2.17 mSv in CA and 6.71 mSv in PCI. Female breast doses was 5.45 mSv in CA and 16.82 mSv in PCI. LAR estimates for CA varied from 1 in 1,508 for man to 1 in 1,357 for women. In PCI procedure varied from 1 in 553 for man to 1 in 482 for women. DAP can be used as the dose indicator to calculate the organ dose and effective dose of patient based on Monte Carlo simulation. These dose estimates derived from our simulation models suggest that CA and PCI are associated with a nonnegligible LAR of cancer. This risk varies markedly and is considerably greater for women, PCI than for man, CA.
Keywords
Coronary angiography; Effective dose; Organ dose; Lifetime attributable risk;
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1 Andrew JE, Kevin WM, Randall CT, Manuel DC, Milena JH: Radiation dose to Patients From Cardiac Diagnostic Imaging. Circulation, 116, 1290-1305, 2007   DOI   ScienceOn
2 Bor D, $Ol\breve{g}ar$ T, Toklu T, $Ca\breve{g}lan$ A, Onal E, Padovani R: Patient doses and dosimetric evaluations in interventional cardiology. Phys Med, 25(1), 31-42, 2009   DOI   ScienceOn
3 D Harrison, M Ricciardello, L Collins: Evaluation of radiation dose and risk to the patient from coronary angiography. Aust NZ J Med, 28, 597-603, 1998   DOI   ScienceOn
4 Efstathios PE, Makrygiannis SS, Kottou S, et al.: Medical personnel and patient dosimetry during coronary angiography and intervention. Phys Med Biol, 48, 3059-3068, 2003   DOI   ScienceOn
5 Sandborg M, Fransson SG, Petterson H: Evaluation of patient-absorbed doses during coronary angiography and interventional by femoral and radial artery access. Eur Radiol, 14, 653-658, 2004   DOI   ScienceOn
6 Kuon E, Dahm JB, Schmitt M, Glaser C, Gefeller O, Pfahlberg A: Time of day influences patient radiation exposure from percutaneous cardiac interventions. Br J Radiol, 76, 189-191, 2003   DOI   ScienceOn
7 Kuon E, Glaser C, Dahm JB: Effective techniques for reduction of radiation dosage to patients undergoing invasive cardiac procedures. Br J Radiol, 76, 406-413, 2003   DOI   ScienceOn
8 Padovani R, Bernardi G, Malisan MR, Vano E, Morocutti G, Fioretti PM: Patients dose related to the complexity of interventional cardiology procedures. Radiat Prot Dosimetry, 94(1-2), 189-192, 2001   DOI
9 Tapiovaara M, Lakkisto M, Servomaa A: A PC-based Monte Carlo program for calculating patient doses in medical X-ray examinations. STUK-A 139, Helsinki Finland; Program version 1.5, 2001
10 K Faulkner, DA Broadhead, RM Harrison: Patient dosimetry measurement methods. Applied Radiation and Isotopes, 50(1), 113-123, 1999   DOI   ScienceOn
11 Committee to Assess Health Risks from Exposure to low levels of Ionizing Radiation; Nuclear and Radiation Studies Board, Division on Earth and Life Studies, National Research Council of the National Academies. Health risks from Exposure to Low Levels of Ionizing Radiation, BEIR Ⅶ Phase 2. Washington, DC: The National Academies Press; 2006
12 Tsapaki V, Kottou S, Vano E, et al.: Patient dose values in a dedicated Greek cardiac centre. Br J Radiol, 76, 726-730, 2003   DOI   ScienceOn
13 Wilde P, Pitcher EM, Slack K: Radiation hazards for the patient in cardiological procedures. Heart, 85, 127-130, 2001   DOI
14 Schueler BA, Julsrud PR, Gray JE, John GS, Kan KW: Radiation exposure and efficacy of exposure-reduction techniques during cardiac catheterization in children. Am J Roent, 162, 173-177, 1994   DOI   ScienceOn
15 Harrison D, Ricciardello M, Collins L: Evaluation of radiation dose and risk to the patient from coronary angiography. Aust NZ J Med, 28, 597-603, 1998   DOI   ScienceOn
16 Delichas MG, Psarrakos K, Molyva-Athanassopoulou E, Giannoglou G, Hatziioannou K, Papanastassiou E: Radiation doses to patients undergoing coronary angiography and percutaneous transluminal coronary angioplasty. Radiat Prot Dosimetry, 103(2), 149-154, 2003   DOI   ScienceOn
17 Stisova V: Effective dose to patient during cardiac interventional procedures(Prague workplaces). Radiat Prot Dosimetry, 111(3), 271-274, 2004   DOI   ScienceOn
18 Vijayalashmi K, Kelly D, Chapple CL, et al.: Cardiac catheterisation: radiation doses and lifetime risk of malignancy. Heart, 93, 370-371, 2007   DOI   ScienceOn
19 Neofotistou V, Vano E, Padovani R, et al.: Preliminary reference levels in interventional cardiology. Eur Radiol, 13, 2259-2263, 2003   DOI   ScienceOn
20 Hynes DM, Gershater R, Edmonds EW, Rowlands JA, Baranoski D, Turow DG: Radiation dose implications of digital angiographic systems. Am J Roent, 143, 307-312, 1984   DOI   ScienceOn
21 마상철, 김함겸, 박병섭, 구효근, 유상재, 백성일 등: Vascular and Interventional Radiology, 대학서림,2008
22 Baldazzi G, Corazza I, Rossi PL, et al.: In vivo effectiveness of gadolinium filter for paediatric cardiac angiography in terms of image quality and radiation exposure. Phys Med, 18, 109-113, 2002