• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.598-601
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• 2016

최근 알파고로 인해 인공지능의 인기가 급부상하고 있고 '머신러닝'의 가능성과 위상을 널리 알려 컴퓨터 및 여러 분야에서 연구단계를 넘어 실용화, 상업화 될 가능성을 확인 시켜주었다. 본 연구는 전망 있는 인공지능산업에 발맞춰 비록 '알파고' 같은 고성능 완벽한 인공지능이 아니지만 랜덤 상태의 초기에서 한 최적의 해를 찾기 위한 도구로서, 유전알고리즘(genetic algorithms)을 사용하여 목표 값에는 최대한 수렴하도록 하는 학습형 AI 게임을 개발하였다. 본 연구에서 개발한 게임은 향후 각각의 다양한 개성을 가진 양산형 인공지능 게임개발에 응용되리가 사료된다.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.3
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• pp.253-260
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• 2020

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disease that can be described by the occurrence of dementia due to a decline in cognitive function. The disease is characterized by the formation of extracellular and intracellular amyloid plaques. Amyloid beta (Aβ) is a hallmark of AD, and microglia can be activated in the presence of Aβ. Activated microglia secrete pro-inflammatory cytokines. Furthermore, S100A9 is an important innate immunity pro-inflammatory contributor in inflammation and a potential contributor to AD. This study examined the effects of metformin and α-LA on the inflammatory response and NLRP3 inflammasome activation in Aβ- and S100A9-induced BV-2 microglial cells. Metformin and α-LA attenuated inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6). In addition, metformin and α-LA inhibited the phosphorylation of JNK, ERK, and p38. They activated the nuclear factor kappa B (NF-κB) pathway and the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome. Moreover, metformin and α-LA reduced the marker levels of the M1 phenotype, ICAM1, whereas the M2 phenotype, ARG1, was increased. These findings suggest that metformin and α-LA are therapeutic agents against the Aβ- and S100A9-induced neuroinflammatory responses.

• Journal of the korean veterinary medical association
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• v.20 no.4
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• pp.193-198
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• 1984

• Proceedings of the Korean Nuclear Society Conference
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• 2004.05a
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• pp.268.2-268.2
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• 2004

• Analytical Science and Technology
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• v.17 no.1
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• pp.85-89
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• 2004

Fragrance components of lilac (Syringa vulgaris) blossom have been characterized in this paper. The accurate characterization of fragrances collected from lilac blossom was carried out by solid-phase trapping-solvent extraction and gas chromatography-ion trap mass spectrometry. According to lilac species, the chemical compositions were significantly different. Benzaldehyde, phenylacetaldehyde, and ${\alpha}$-farnesene were found as the predominant component of white lilac blossom whereas benzaldehyde, ${\alpha}$-pinene, and ocimene were those of pale purple lilac. The enantiomeric analysis of ${\alpha}$-pinene in lilac blossom was found in the form of ( ).

• Proceedings of the Korean Institute of Building Construction Conference
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• 2011.11a
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• pp.109-110
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• 2011

Gypsum is an important building material used to provide fire resistance to constructions by reducing their temperature rises. As the hardened gypsum is exposed to fire, evaporation of both the free water and the chemical bond water is easier than that in the cement extruding panel. The purpose of this study is to investigate the utilizability of alpha-hemihydrate gypsum to prevent spalling failure of cement extruding panel exposed to fire. This paper reports the fire-resistance property of a controled general cement extruding panel(C100), and gypsum-cement extruding panels(C50A50, A100) according to replacement ratio of alpha-hemihydrate gypsum. As a results, it is found that A100 and C50A50 are more effective to prevent the explosive spalling failure under standard fire condition than C100.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2004.09a
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• pp.142-146
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• 2004

지하수중에 존재하는 극미량의 환경방사성 동위원소를 측정하기 위한 방법을 개발하였다. 각 핵종들중 234U, 238U, 222Rn, 226Ra은 섬광액을 포함한 용매추출법을 사용하여 개별분리한 후 액체섬광계수기를 사용하여 각 핵종에서 방출되는 알파선을 검출하였다. 환경방사성 원소인 U과 Th 딸핵종의 비평형에 의한 지하수 특성 연구를 위해서 국내 지하수 중의 234U와 238U의 방사능비 측정을 대전 화강암 지역에서 채취한 지하수 시료를 ICP/MS를 사용하여 U 함량을 결정하고, 지하수에서 U을 용매추출한 후 알파전용 액체섬광계수기를 사용하여 234U와 238U의 방사능을 측정하였다.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2000.11a
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• pp.15-15
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• 2000

• Proceedings of the Korean Ceranic Society Conference
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• 2000.10a
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• pp.166.2-166
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• 2000

• Proceedings of the Korean Ceranic Society Conference
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• 2000.10a
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• pp.170.1-170
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• 2000