• Journal of Chest Surgery
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• v.37 no.4
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• pp.376-381
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• 2004

Primary cardiac lymphoma is an extranodal malignant lymphoma of any cell type involving only heart and pericardium without dissemination. Patients usually present symptoms of heart failure, arrhythmias, pericardial effusion and cardiac tamponade. Diagnosis of primary cardiac lymphoma can be performed by echocardiogram, CT and MRI and cytologic examination of pericardial effusion or transvenously biopsied cardiac tissue. Prognosis of primary cardiac lymphoma is poor. Because of poor prognosis, early diagnosis and complete surgical excision is essential and postoperative systemic chemotherapy or radiotherapy is useful. In this case extensive tumor infiltration on the right ventricle and atrioventricular groove preclude surgical excision. Tissue biopsy revealed primary cardiac lymphoma. After postoperative chemotherapy and radiotherapy, the size of intracardiac mass is decreased in follow up chest CT scan and echocardiogram and symptoms of patient are relieved. Therefore, we report a case of primary cardiac lymphoma with review of literatures.

• Journal of Chest Surgery
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• v.36 no.10
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• pp.776-779
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• 2003

An eight-year-old boy was referred to our hospital with cough and high fever. His past medical history included a small sized ventricular septal defect (VSD) at birth. Transthoracic echocardiography disclosed a 10 x 6 mm vegetation on tricuspid valve, a small VSD and the moderate tricuspid valve insufficiency were found. Blood cultures grew methicillin-resistant staphylococcus aureus. Despite proper antibiotic therapy, fever was not controlled and his course was complicated by pulmonary infarction. The patient simultaneously underwent pulmonary resection and open heart surgery. Through the median sternotomy we performed open thrombectomy and lobectomy (right lower lobe) at first, and then vegetectomy, tricuspid valve repair, and direct closure of VSD were done under cardiopulmonary bypass.

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.643-649
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• 2017

심장 이온통로의 변화는 활동전압의 모양과 길이에 영향을 주어 심부정맥을 유발한다. 산화적 스트레스의 증가로 인해 생체에 침착이 증가하는 지질산화물 (4-HNE, 4-ONE)는 여러 단백질 및 이온통로에 영향을 주는 독성이차전달자로 알려져 있다. 본 연구자는 선행 연구를 통해 4-HNE와 4-ONE의 단기간 노출이 심실근세포에 발현되는 3종류의 이온통로 ($I_{Kr}$, $I_{Ks}$, $I_{Ca,L}$)의 전류감소와 kinetics변화를 일으키고, 심실근세포의 활동전압길이가 증가하는 것을 확인하였다. 두 물질이 이온통로들에 준 영향은 유사하였으나, 활동전압길이의 증가 정도가 4-ONE에서 더 크게 나타났다. 활동전압의 연장에 차이가 나는 원인과, 두 지질산화물이 또 다른 이온통로에 미치는 영향 유무를 예측하기 위해서 Grandi and Bers human ventricular model[1]을 적용한 Integrated human ventricular myocyte model 프로그램 (developed by prof. Youm)을 활용하였다. 시뮬레이션으로 재현한 4-HNE와 4-ONE에 의한 활동전압은 실험으로 기록된 것보다 연장 정도가 작았다. 시뮬레이션 모델의 background $Na^+$ 전류의 크기를 크게 하였을 경우, 실험에서 기록된 활동전압 길이에 상응하는 연장을 가져왔다. 그러므로, 4-HNE와 4-ONE는 실험으로 확인한 $I_{Kr}$, $I_{Ks}$, $I_{Ca,L}$ 이외에 심장세포에 존재하는 내향전류 (Late $Na^+$ current)의 크기를 증가하는 효과가 있음을 예측할 수 있으며, 실험적 검증이 요구된다.

• Journal of Chest Surgery
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• v.29 no.3
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• pp.311-314
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• 1996

Eighteen patients (13 female and ave male) aged from 15 to 62 years (mean age 42.6 years) underwent excision of cardiac myxoma(17 left atrial, one right atrial) between 1985 and 1994 at Pusan National University hospital. All patients complained of exertional dyspnea and most had a few additional symtoms including palpitation, chest pain, syncope, general weakness, weight loss, fever, cough and epigastric disconyort. The diagnosis was made by echocardiography alone in left atrial myxomas but a myxoma in right atrium was diagnosed incidentally during mitral valve replacement for rheumatic valvular heart disease. The tumor attachment sites were fossa ovalis in 13, other interatrial septum in 4, mitral valve annulus in one and free wall of left atrium in two cases. The tumor was excised successfully via right atriotomy in 8 and biatriotomy in 10 cases. There was no hospital nor late death, and no recurrent case during the follow up period. Curative surgical excision of cardiac myxoma can be performed with low morbidity and very low r currence rate.

• The Journal of the Acoustical Society of Korea
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• v.32 no.1
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• pp.32-42
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• 2013

Typical underwater piezoelectric spherical sensors are omni-directional, thus can measure the scalar quantity sound-pressure-magnitude only with the limitation not being able to measure the direction of the incoming wave. This paper proposes a method to simultaneously measure both the magnitude and direction of the sound wave with the spherical sensor. The method divides the piezoceramic sphere of the sensor into eight elements, and distinguishes the magnitude and direction of the sound pressure by combining the output voltage of the elements in a particular manner. Further, through the analysis of the sensitivity variation in relation to the structural parameters like radius and thickness of the piezoceramic sphere, we have suggested the way to improve the sensitivity of the vector sensor.

• Proceedings of the Korea Multimedia Society Conference
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• 2001.11a
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• pp.873-876
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• 2001

관상 동맥 질환은 관상 동맥 내벽에 플라크(Plaque)가 침착된 결과 혈관이 좁아져서 생기는 질환으로, 혈관이 좁아져 심장으로의 혈류가 감소하고, 혈전이 동맥을 막아 심장 발작을 일으킨다. 본 논문에서는 관상동맥 질환의 객관적 분석을 위한 분할 방법론과 분할된 영역으로부터 정량적 분석 방법을 제안한다. 동맥 단면영상으로부터 정량 분석을 위해 획득한 단면영상을 현미경으로부터 12.5배 배율로 얻었으며, 정량 분석을 위해 혈관의 각 영역을 분할하여 분할영역의 크기, 최대 장축 등의 정보를 추출하였다. 본 논문에서 제시한 알고리즘을 사용하여 수 작업에 의한 혈관 단면 분석을 자동화하면, 3차원적 변화량에 따른 정량분석 결과를 얻을 수 있을 것이다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.07a
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• pp.355-356
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• 2013

심장의 활동을 전기적 변위로 표현되는 심전도 신호는 심장병 진단에 중요한 임상적 파라미터들을 제공한다. 특히 심전도 신호에서 P, QRS Complex,, T 특징점들로 대표되는 파형 변곡점들의 시간상 위치와 크기 및 형태학적 모양은 심장의 이상 리듬을 나타내는 부정맥여부를 검출하는데 핵심적인 역할을 한다. 본 연구에서는 특히 QRS complex 구간에 대한 첨도치의 연산 해석을 통하여 정상적인 심전도 리듬과 심실조기수축 부정맥 리듬을 구분하는 방법을 제시하고 또한 스마트폰을 기반으로 하는 심전도 모니터링 시스템에 적용하고자 하였다.

• Journal of radiological science and technology
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• v.39 no.2
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• pp.135-142
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• 2016

The purpose of this study is to evaluate propriety of using SID 180cm at Chest PA examination and to find effect of geometrical cause to the image. XGEO-GC80, INNOVISION-SH, CXDI-40EG detector and a chest phantom designed self-production was used for this study. Images were acquired at SID 180cm with changing the factor OID as 0, 75 and 83mm and were analyzed by Centricity Radiography RA1000 PACS system. Statistical program was used the SPSS (Version 22.0, SPSS, Chicago, IL, USA), p-value(under 0.05) was considered to be statistically significant. In OID 0 mm was enlarged about 2.7~3.5 mm than the actual degree of the HS, BS of phantom in all equipments. Compared with the calculated magnification has been expanded 1.6~2.8% when viewed. The OID 75 mm with OID 83 mm was extended from the CS and BS 6~8 mm range. Compared to the calculated values, the measured values are expanded from 6.1 to 7.9%. CS and BS according to the OID change showed a statistically significant difference (p<0.05) among each group, the post-analysis only OID 0 mm group appeared as an independent group, 75 mm and 83 mm are separated in the same group It was. But had no statistically significant difference could change depending on the OID (p>0.05), post-mortem analysis showed, both in the same group. Heart sizes appears larger than actual size 6~8 mm at chest PA examination which is enlarged 6.1~7.9% more than the actual theoretical value. We can find magnification of the image because of the increase of the OID due to technical limitations between cover of standing detector and the image plate. so we suggest to have occurred between them when considering the need to adjust the equipment installed by the SID to match the characteristics of the equipment.

• Journal of Chest Surgery
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• v.36 no.2
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• pp.101-104
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• 2003

Although lung transplantation has been accepted as the most effective treatment for end-stage pulmonary emphysema, it is not only very hard to find a donor but also to obtain a relatively healthy lung. Furthermore, it is more difficult to match the size of the allograft, considering the height, the weight, and the size of the thoracic cage. The single lung transplatations for the end-stage emphysema have been more commonly performed than bilateral lung transplantation due to the shortage of the donors and the long-term survival rate of the single lung transplantations has shown no reasonable difference compared with that of the bilateral lung transplantationh. Recently, the functional criteria based on a comparison of predicted TLCs(Total Lung Capacities) of the donor and recipient according to height, sex and age, have been accepted at a more suitable.

• Clinical and Experimental Pediatrics
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• v.46 no.9
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• pp.871-875
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• 2003

Purpose : This study was performed to follow the natural course and size change of isolated atrial septal defect(ASD) secundum. Methods : Among the newly diagnosed with ASD secundum at the division of pediatric cardiology in Yonsei cardiovascular hospital from January 1996 to December 2000, 89 patients with pure ASD secundum were checked by the serial echocardiographic evaluation to measure the size change. Results : There was a statistical difference(P<0.05) in the rate of spontaneous closure and size change of the defect between the group of bigger defect(>8 mm) and the group of smaller defect (${\leq}8mm$). There was also a statistical difference(P<0.05) in the rate of spontaneous closure and size change of the defect between the group of younger than three years of age and the group of older than three years of age. The initial size of the defect and change of size were the significant influencing factors in the rate of spontaneous closing of ASD. In the group of patients who have persistent ASD, the size of defect showed a tendency of increasing size of defect with the age(P<0.005); however in the correction of these values by the body surface area of each patients, there was no statistical difference. Conclusion : The possibility of spontaneous closure of pure ASD secundum was higher in the group of patients who have smaller defect and who were younger. The ASD secundum that did not have spontaneous closure showed an increase in size with the growth of the patients; however when this size was corrected by the body surface area, there was no statistical difference. The closure of the defect was at 26.2 months of age so close follow-up of the patients is important.