• 전기의세계
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• v.37 no.7
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• pp.81-86
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• 1988

임피던스 혈량 측정법(impedance plethysmography)은 인체의 어느 특정부위에서의 혈량의 변화를 환자에게 전혀 고통을 주지않고(noninvasive) 안전하고 간편하게 측정하는 방법으로서, 특히 심장의 빅동량(stroke volume)를 측정하는 분야를 임피던스 카디오그라피(impedance cardiography)라고 한다. 혈량 측정법은 인체의 어느 부위에서 박동하는 혈량은 그 부위로 유입되는 혈량과 유출하는 혈량의 차이 만큼 유발한다는데 근거를 두고 있다. 한편 심전도는 주로 심장의 전기적인 면을 측정하는 반면 임피던스 카디오그라피는 박동량과 심장 근육의 수축능력(contractility)등 심장의 기계적인 면을 측정할 수 있다.

• Journal of Convergence for Information Technology
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• v.11 no.7
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• pp.164-171
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• 2021

This study analyzed the post-exercise cardiopulmonary function, maximal oxygen uptake, heart rate and recovery time through smoker's short - term smoking cessation and trunk stabilization exercise for 72 hours. We analyzed the effect of trunk stabilization exercise on the cardiopulmonary function of smokers and non-smokers. As a result, it was found that both smokers and non-smokers groups showed significant changes in pulmonary function (FVC, SVV, MVV), maximal oxygen uptake, recovery time Difference. This suggests that the trunk stabilization exercise may have a positive effect on the cardiopulmonary function of short-term non-smokers as well as non-smokers for a short period of time, and a more stable and effective method for preventing and improving the reduction of cardiorespiratory function

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.653-655
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• 2017

심근섬유증은 심장에서 전도 장애를 일으키며 심부전증상을 발생시킨다. 심근섬유증으로 인한 심장박동현상의 변화를 확인하기 위해 시뮬레이션 연구를 진행하였다. 심실의 유한요소 모델을 설계하고 무작위로 전도 블록을 생성하여 심근섬유증을 적용하고 그 비율을 조절하였다. 심근섬유증의 비율에 따라 전기생리학적 시뮬레이션을 진행하고 그 결과를 바탕으로 기계 수축 시뮬레이션을 진행하여 심실의 수축 변화를 확인하였다. 심근섬유증의 비율이 증가할수록 좌심실의 압력이 감소하고 박출되는 혈액량과 박출계수, 심장박동의 효율이 감소하였다.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.501-504
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• 2006

The estimation of the work of heart can be treated as one of the most important parameters for determining the amount of circulating blood needed for harmonious metabolism in the human body. By monitoring the work of heart, one can detect increased work load of heart and start the treatment at the early stage of CHF. Thus it is necessary to estimate the work of heart. The contractility of the left ventricle, the second important parameter for representing the motion of heart, can be estimated through information on the work of heart. In this study, the modified Windkessel model, which has been used for a measure of vascular hemodynamic impedance parameters, was adapted to estimate the work of heart.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.19 no.3
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• pp.62-74
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• 2020

Although the government and local governments devote efforts to activate bicycles, they only access to the supply infrastructure such as bike lanes and the public bicycle rental service centers without considering the measures to overcome the geographical constraints of slope. Therefore, this study constructs bicyclist's energy consumption estimation model through experimental methods of slope gradient and heart rate measurement and suggest the bicycle route choice model which could minimize the energy by the slope gradient. After calculating the RMSE of the estimated energy consumption by applying this model to the simulation section, it is confirmed to be 41% better than the model which does not reflect slope gradient. The results of this study are expected to be applied to the bicycle infrastructure planning that considers both longitude and transverse of bike lanes and the algorithm of bicycle route guidance system in the future.

• Journal of Chest Surgery
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• v.38 no.2 s.247
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• pp.101-109
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• 2005

Background: In sudden cardiac arrest, the effective maintenance of coronary artery blood flow is of paramount importance for myocardial preservation as well as cardiac recovery and patient survival. The purpose of this study was to directly compare the effects of pulsatile and non-pulsatile circulation to coronary artery flow and myocardial preservation in cardiac arrest condition. Material and Method: A cardiopulmonary bypass circuit was constructed in a ventricular fibrillation model using fourteen Yorkshire swine weighing $25\~35$ kg each. The animals were randomly assigned to group I (n=7, non-pulsatile centrifugal pump) or group II (n=7, pulsatile T-PLS pump). Extra-corporeal circulation was maintained for two hours at a pump flow of 2 L/min. The left anterior descending coronary artery flow was measured with an ultrasonic coronary artery flow measurement system at baseline (before bypass) and at every 20 minutes after bypass. Serologic parameters were collected simultaneously at baseline, 1 hour, and 2 hours after bypass in the coronary sinus venous blood. The Mann-Whitney U test of STATISTICA 6.0 was used to determine intergroup significances using a p value of < 0.05. Result: The resistance index of the coronary artery was lower in group II and the difference was significant at 40 min, 80 min, 100 min and 120 min (p < 0.05). The mean velocity of the coronary artery was higher in group II throughout the study, and the difference was significant from 20 min after starting the pump (p < 0.05). The coronary artery blood flow was higher in group II throughout the study, and the difference was significant from 40 min to 120 min (p < 0.05) except at 80 min. Serologic parameters showed no differences between the groups at 1 hour and 2 hours after bypass in the coronary sinus blood. Conclusion: In cardiac arrest condition, pulsatile extracorporeal circulation provides more blood flow, higher flow velocity and less resistance to coronary artery than non-pulsatile circulation.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.11
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• pp.1191-1198
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• 2011

The use of a ventricular assist device (VAD) can raise the one-year survival rate without cardiac transplantation from 25% to 52%. However, malfunction of the VAD system causes 6% of VAD patients' deaths, which could possibly be avoided through the development of new VADs in which VAD malfunctions do not affect the patient's heart movement or hemodynamic state. A conventional VAD has an impeller or vane for propelling blood that can allow blood to regurgitate when the propelling force is weaker than the aortic pressure. In this paper, we developed a new pulsatile conduit-shaped VAD that has two valves. This device removes the possibility of blood regurgitation and has a small stationary area even when the pumping force is extremely weak. We estimated the characteristics of the device by measuring the outflow and the pressure of the pump in in-vitro and in-vivo experiments.

• Journal of Chest Surgery
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• v.38 no.1 s.246
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• pp.13-22
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• 2005

It has been known that pulsatile flow is physiologic and more favorable to tissue perfusion than nonpulsatile flow. The purpose of this study is to directly compare the effect of pulsatile versus nonpulsatile blood flow to renal tissue perfusion in extracorporeal circulation by using a tissue perfusion measurement system. Material and Method: Total cardiopulmonary bypass circuit was constructed to twelve Yorkshire swines, weighing 20$\~ $30 kg. Animals were randomly assigned to group 1 (n=6, non pulsatile centrifugal pump) or group 2 (n=6, pulsatile T-PLS pump). A probe of the tissue perfusion measurement system $(QFlow^{TM}-500)$ was inserted into the renal pa­renchymal tissue. Extracorporeal circulation was maintained for an hour at a pump flow of 2 L/min after aortic cross-clamping. Tissue perfusion flow of the kidney was measured at baseline (before bypass) and every 10 minutes after bypass. Serologic parameters were collected at baseline and 60 minutes after bypass. Result: Baseline parameters were not different between the groups. Renal tissue perfusion flow was substantially higher in the pulsatile group throughout the bypass (ranged 48.5$\~$ 64 in group 1 vs. 65.8$\~$88.3 mL/min/100 g in group 2, p=0.026$\~$ 0.45) The difference was significant at 30 minutes bypass $(47.5{\pm}18.3\;in\;group\;1\;vs.\;83.4{\pm}28.5$ mL/min/100 g in group 2, p=0.026). Serologic parameters including plasma free hemoglobin, blood urea nitrogen, and creatinine showed no differences between the groups at 60 minutes after bypass (p=NS). Conclusion: Pulsatile flow is more beneficial to tissue perfusion of the kidney in short-term extracorporeal circulation. Further study is suggested to observe the effects to other vital organs or long-term significance.

• Journal of Chest Surgery
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• v.29 no.7
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• pp.689-699
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• 1996

An animal experiment was designed for the evaluation of in vivo performance of the newly developed electrohydraulic type ventricular assist device and its influence on the left ventricular function during pal- satile left ventricular assist. Eight adult sheep were incorporated into the study and data were collected from seven sheep. Total as- sist time ranged from 69 minutes to 7 days. The performance of the device was satisfactory both in asyn- chr nous and synchronous mode within the range of given native heart rate. More than 4 liters of device output could be reached within the range of normal left atral pressure without development of negative pressure in the left atrium. Moderate to severe degree of hemolysis was noted as evidenced by significant increase of plasma free hemoglobin level after 3 days of left ventricular support along with the presence of the small amount of thrombi around the floating disc type polymer valve apparatus reflecting that further study and refinement of the device need to be done in regard of biocompatibility and thromboresistance. The hemodynamics showed increase in heart rate (p < 0.05), cardiac output and left ventricular minute work (p < 0.05) after placement of the device at the flow rate of 2.0∼2.5 Llmin. The left atrial pressure, left ventricular pressure and LV dpldt were decreased after the device placement(p < 0.05). The endocardial viability ratio and oxygen contents of the mixed ven us blood and coronary venous blood were all increased (p < 0.05) after the device placement suggesting effective unloading of the left ventricle was accomplished. The myocardial perfusion was thought improved in synchronous counterpulsation as suggested by sig- nificant increase in endocardial viability ratio and coronary venous blood oxygen content in synchronous assist mode comparing with asynchronous mode.

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.142-151
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• 1997

본 연구는 주부들의 주활동공간인 부엌가구와 공간의 설계에 있어사용하기 편리하며 가사활동에 따 른 피로를 경감시키고 요통과 같은 주부직업병을 예방할 수 있는 부엌가구와 공간의 개발에 그 목적을 두었다. 연구는 먼저 수도권의 32평형 규모의 아파트150가구를 대상으로 설문조사를 실시하였으며, 만 24시간동안의 실제 가사활동을 Video로 촬영하여 동작분석을 실시하였다. 그 결과 주부들은 수납의 용 이성과 공간의 크기, 작업대의 높이 등을 가장 많은 개선사항으로 지적하였으며, 절반이상의 주부들이 앉은 자세에서 작업이 이루어졌으면 좋겠다고 응답하였다. 또한 동작분석 결과 작업의 70%이상이 개수 대를 중심으로 조리대와 가열대 주변의 한정된 공간에서정적으로 선 자세에서이루어지는 것으로 파악 되었다. 이러한 선 자세에서의 작업에 따른 피로도를 감소시키기 위하여 입좌식 의자를 도입하였으며, 개수대를 씽크대의 'ㄱ'자 코너에 위치하여 주방활동시의 이동거리를 단축하고자 하였다. 피로도의 경감 을 측정하기 위하여 입좌식 의자를 도입한 개선된 씽크대와 기존의 입식씽크대에서 가사활동시 요구되는 주부들의 에너지 대사량을 비교하기 위하여 심장박동수와 산소호흡량을 측정하였다. 실험결과에 따르면 주방에 입좌식의자를 도입한 경우가 가사활동에 요구되는 에너지 소모량이 심장박동수와 산소호흡량의 기준에서 각각 평균적으로 30%와 57.5% 이상이 감소하는 것으로 파악되어 이러한 부엌가구의 도입으로 주부들의 가사활동에따른 피로도가 절반 가까이 감소될 수 있음을 니타내었다. 또한 부엌가구의 재배치 에따른 가사활동시 이동거리가 평균적으로5.5%이상이 감소하는 것으로 나타났다. 본 연구결과를 주방설 계에 적용할 경우 가사활동의 효율성과 편리성이 향샹됨은 물론 가사활동에따른 피로도를 경감 시키고 요통 등의 주부직업병을 예방할 수 있을 것으로 기대된다.1일 1회씩 4회 투여한 군에서도 암수에 상관없이 전 농도 군에서 염색체이상을 나타내지 않아 유전독성을 나타내지 않음을 관찰하였다. 특히 vitamin C와 E의 병용투여는 상승적으로 적용하여 간세포손상을 더욱 억제시킴을 알 수 있었다.mance and on TFP(Total Factor Productivity) growth which is a pure measure of firm performance. To utilize the advantage of panel data, FEM(Fixed Effect Model) and REM(Random Effect Model) were used. The empirical result shows that the entropy index as a measurement of inter-business relatedness is not significant but technological relatedness index is significant. OLS estimates on pooled data were considerably different from FEM or REM estimates on panel data. By introducing interaction effect among the three variables for business portfolio properties, we obtained three findings. First, only VI (Vertical integration) has a significant positive correlation with ROS. Second, when using TFP growth as an dependent variable, both TR(Technological Relatedness) and f[ are signif