• Title/Summary/Keyword: 심부구조

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Pathophysiology and therapeutics in heart failure (심부전증의 병리 기전과 치료)

  • 현창백
    • Journal of the korean veterinary medical association
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    • v.40 no.3
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    • pp.227-240
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    • 2004
  • 심부전증(Heart failure)이란 심장이 조직에서 필요로 하는 산소나 영양분을 제대로 공급하지 못하는 상태로 심장 자체의 구조적 결함이외에도 혈역학(hemodynamics)에 영향을 주는 신장 질환이나 고혈압등에 의해서도 발생한다. 심장은 커다란 펌프로 혈역학적 변화에 능동적으로 대처할 능력을 가지고 있다. 하지만 이러한 혈역학의 변화를 유발하는 원인을 제거하지 않은채 장기적으로 원인이 지속할 경우, 심장, 특히 심실은 재구성(remodeling)이 일어나게되고(좌심실의 벽이 비후되고 우심실의 벽이 얇아지는 변화) 이로인하여 심장의 혈역학 변화에 따른 보상 반응은 점차 무력화 되게된다. 이로인하여, 혈액 정체에 따른 폐부종이나 복수증 및 산소 부족에 의한 허혈성 손상이 여러 장기에 나타나게 된다. 심장 질환은 불량한 예후와 치료의 제한성때문에 그동안 수의 분야에서 간과되어왔지만, 우리나라도 애완동물의 노령화가 시작되고 있고 고급 진료에 대한 축주들의 요구가 증가하고 있어서 점파 심장 질환의 진료가 늘어갈 것으로 사료된다. 따라서 본 종설에서는 심부전증에 대한 여러 가지 병리 기전과 이에 따른 치료 방법에 대해 기술하고자한다.

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석회석 자원 탐사 및 개발의 효율성 증대를 위한 통합 층서적 접근

  • 유인창
    • Proceedings of the Mineralogical Society of Korea Conference
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    • 2002.10a
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    • pp.69-92
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    • 2002
  • 비금속 및 금속 광물자원의 탐사는 국가경영에 있어서 절대적으로 필요한 공공의 기반산업에 해당된다. 지금까지 수행되어 왔던 자원 탐사사업의 대부분은 비교적 개발이 용이한 천부 광상들에 집중되어 왔으며, 천부 광상들의 과도한 개발로 인하여 자원탐사의 범위가 점차 심부화 되고있는 실정이다. 지하 심부에 분포하는 광상들을 효율적으로 탐사해 내기 위해서는 분지 내 심부 퇴적층들에 대한 정밀한 대비와 평가가 요구된다. 그러나, 그 동안 천부 광상들의 평가에 적용되어 왔던 기재적 층서 원리들로는 심부에 분포하는 광상들을 도출해 내는데 한계가 있어 왔다. 따라서, 분지 내 퇴적층들에 대한 보다 명확한 이해를 위해 새로운 고해상도의 층서틀 수립이 시급하다. 본 연구에서는 태백산분지 오오도비스 중기 퇴적층들에 대한 통합 층서적 접근을 통하여 고해상도 층서틀 수립에 대한 예를 제시하고자 한다. 이러한 통합 층서적 접근은 퇴적 분지의 지체 구조적 진화에 따른 층서를 규명하는데 있어서 보다 나은 통찰을 제공하고 있으며, 아울러 분지 내 비금속 및 금속 광물자원 탐사 및 개발사업의 효율성을 증대시키는데 사용될 수 있을 것이다 따라서, 통합 층서적 접근을 통한 퇴적층들에 대한 고해상도 층서틀 수립은 분지 내에 부존 되어 있는 모든 형태의 자원 탐사 및 개발사업에 있어서 성공률을 극대화시킬 수 있는 새로운 층서적 규범으로 강조되어 져야 한다.

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석회석 자원 탐사 및 개발의 효율성 증대를 위한 통합 층서적 접근

  • 유인창
    • Proceedings of the KSEEG Conference
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    • 2002.10a
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    • pp.69-92
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    • 2002
  • 비금속 및 금속 광물자원의 탐사는 국가경영에 있어서 절대적으로 필요한 공공의 기반산업에 해당된다. 지금까지 수행되어 왔던 자원 탐사사업의 대부분은 비교적 개발이 용이한 천부 광상들에 집중되어 왔으며, 천부 광상들의 과도한 개발로 인하여 자원탐사의 범위가 점차 심부화 되고있는 실정이다. 지하 심부에 분포하는 광상들을 효율적으로 탐사해 내기 위해서는 분지 내 심부 퇴적층들에 대한 정밀한 대비와 평가가 요구된다. 그러나, 그 동안 천부 광상들의 평가에 적용되어 왔던 기재적 층서 원리들로는 심부에 분포하는 광상들을 도출해 내는데 한계가 있어 왔다 따라서, 분지 내 퇴적층들에 대한 보다 명확한 이해를 위해 새로운 고해상도의 층서틀 수립이 시급하다. 본 연구에서는 태백산분지 오오도비스 중기 퇴적층들에 대한 통합 층서적 접근을 통하여 고해상도 층서틀 수립에 대한 예를 제시하고자 한다. 이러한 통합 층서적 접근은 퇴적 분지의 지체 구조적 진화에 따른 층서를 규명하는데 있어서 보다 나은 통찰을 제공하고 있으며, 아울러 분지 내 비금속 및 금속 광물자원 탐사 및 개발사업의 효율성을 증대시키는데 사용될 수 있을 것이다. 따라서, 통합 층서적 접근을 통한 퇴적층들에 대한 고해상도 층서틀 수립은 분지 내에 부존 되어 있는 모든 형태의 자원 탐사 및 개발사업에 있어서 성공률을 극대화시킬 수 있는 새로운 층서적 규범으로 강조되어져야 한다.

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Two-dimensional Inversion of Sea-effect-corrected Magnetotelluric (MT) Data in Jeju Island (해양효과가 보정된 제주도 자기지전류 탐사 자료의 2차원 역산)

  • Yang, Jun-Mo;Lee, Heui-Soon;Lee, Choon-Ki;Park, Gye-Soon
    • Journal of the Korean earth science society
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    • v.32 no.6
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    • pp.602-612
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    • 2011
  • Jeju Island, a volcanic island located in South Korea, has been one of the main targets of geophysical and/or geological studies because of its tectonic importance related to the volcanism and tectonic link to the southern part of the Korean Peninsula. Recently, as a number of broad-band magnetotelluric (MT) measurements were made, we have examined the deep part of the island. In such an insular setting, it is not easy to properly recover the deep structures such as the lower crust and the upper crust using MT data, because their low-frequency components are strongly affected by the surrounding sea of the island. In this study, we apply the sea-effect correction to the existing MT data collected at a total of 102 sites in Jeju Island. The sea-effect correction makes remarkable changes in the observed MT data at frequencies below 1 Hz, clearly indicating the existence of a conductive lower crust. The 2-D inversion results for both Jeju Southern Line (JSL) and Jeju Northern Line (JNL) show that the transition zone separating the resistive upper crust and conductive lower crust exists at a depth of 20 km on average.

Frture mapping and deep-seated ground water exploration in the crystalline rocks by integrated geophysical techniques (종합적 물리탐사에 의한 파쇄대 및 심부 지하수 탐사)

  • 정승환;김정호;조인기;전정수
    • The Journal of Engineering Geology
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    • v.2 no.2
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    • pp.113-130
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    • 1992
  • Groundwater in crystalline basement is controlled primarily by tectonic fractures. It is evident that the delineation of the heavily faulted area and/or fractures deeply developped should be considerable value in deep-seated low enthalphy geothermal water. Electrical and electromagnetic methods have effectively been employed to map hydraulic faults and shear zones for groundwater exploration. In this study VLi; dipoledipole resistivity, controlled source audio~frequency magneto-telluric(CSAMT) and magnetic methods were applied in the Bomun resort area, adjacent to Kyongju city, southeastern part of Korea. The integrated geophysical tools employed in this experiment can be manifested themselves as: 1. Magnetic high for granite intrusions which is more favorable for geothermal gradient increase in depth. 2. VLF cross-over trends for mapping linear shallow conductive fractures and shear zones. 3. Dipole-dipole resistivity distributions for the deep-seated(less than 500m in depth) fractures and shear zones. The dipole-dipole resistivity field data were inverted to the true resistivity distribution with two-dimensional automatic inversion program based on the finite-difference method. 4. CSAMT provides an efficient way of delineating fractures and fault zones if the depth is greater than about 500m.

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Establishment of the Heart Failure Model in Swine for the Experiment of the Pneumatic Ventricular Assist Device (공압식 심실보조기의 실험을 위한 돼지에서의 심부전 모델의 개발)

  • 박성식;서필원;이상훈;강봉진;문상호;김삼현
    • Journal of Chest Surgery
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    • v.36 no.3
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    • pp.123-130
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    • 2003
  • Background: In order to develop the acute heart failure model for the animal experiment of the pneumatic ventricular assist device, we decided to use young pig whose coronary artery distribution is almost the same as humans and also very cheap in price. The purpose of this study is to develop stable, reproducible acute ischemic heart failure model in swine using coronary artery ligation method. Material and Method: Five young pigs whose weights are the same as adult humans are under experiment. Each pig was under endotracheal intubation and connected to a mechanical ventilator. Through left lateral thoracotomy, we exposed the heart and induced ischemic heart failure by coronary artery ligation. The ligation began at the distal part of the left anterior descending coronary artery. After 5 minutes of initial ligation we reperfused the artery and then re-ligated. Before and after each ligation-reperfusion procedure we assessed the left ventricular end-diastolic pressure, arterial pressure, and cardiac index. We also measured left ventricular end-diastolic dimension, end-systolic dimension, fractional shortening, ejection fraction using intraoperative epicardial echocardiography. After appropriate heart failure was established with sequential (from distal part of LAD to proximal location) ligation-reperfusion-ligation procedure, we inserted the ventricular assist device and operated. Result: We established stable acute ischemic heart failure in 3 of 5 young pigs with this sequential ligation-reperfusion-ligation procedure, and could maintained 50% less ejection fraction before the procedure according to intraoperative epicardial echocardiography. We also observed no ventricular arrhythmia usually associated with simple coronary artery ligation in large animals and no cardiac arrest associated with ventricular arrhythmia or myocardial stunning. In pathologic specimen, we observed scattered ischemic myocardium in all around the ischemic field induced by coronary artery ligation. Conclusion: Under the concept of ischemic preconditioning, we developed safe and reproducible acute ischemic heart failure model in swine using sequential coronary artery ligation-reperfusion-ligation method.

Integrated stratigraphic approach for enhancing the efficiency of domestic resources exploration and development (국내 자원 탐사 및 개발의 효율성 증대를 위한 통합 층서적 접근)

  • Ryu In-Chang
    • The Korean Journal of Petroleum Geology
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    • v.9 no.1_2 s.10
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    • pp.24-39
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    • 2001
  • Prospecting for energy and mineral resources is essential kind of public fundamentals that manage the nation's economy. Most explorations in the past were concentrated in the simple structural traps in relatively shallow depth. Due to their vast exploitation, recent history has shown that the emphasis in explorations has steadily shifted toward the subtle stratigraphic traps in deeper level. Increasing exploration for the subtle stratigraphic traps in deeper level requires precise correlation and assessment of deeply buried strata in the basin. However, the descriptive stratigraphic principles used for evaluation of the simple structural traps are limited to delineate the subtle stratigraphic traps in deeper depth. As this occurs, it is imperative to establish a new stratigrtaphic paradigm that allows a more sophisticated understanding on the basin stratigraphy. This study provides an exemplary application of integrated stratigraphic approach to defining basin stratigraphy of the Middle Ordovician Taebacksan Basin and the Cretaceous South Yellow Sea Basin, Korea. The integrated stratigraphic approach gives much better insight to unravel the stratigraphic response to tectonic evolution of the basins, which can be utilized for enhancing the efficiency of resources exploration and development in the basins. Thus, the integrated stratigraphic approach should be considered as a new stratigraphic norm that can improve the probability of success in any type of resources exploration and development project.

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Constructing Geological Cross-sections at Depth and Interpreting Faults Based on Limited Shallow Depth Data Analysis and Core Logging: Southern Section of the Yangsan Fault System, SE Korea (제한된 천부자료와 시추코어분석을 통한 심부지질단면도 작성과 단층 인지법: 한반도 남동부 양산단층대 주변에서의 적용)

  • Kim, Taehyung;Kim, Young-Seog;Lee, Youngmin;Choi, Jin-Hyuck
    • The Journal of Engineering Geology
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    • v.26 no.2
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    • pp.277-290
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    • 2016
  • Deep geological cross-sectional data is generally not common nor easy to construct, because it is expensive and requires a great deal of time. As a result, geological interpretations at depth are limited. Many scientists attempt to construct geological cross-sections at depth using geological surface data and geophysical data. In this paper, we suggest a method for constructing cross-sections from limited geological surface data in a target area. The reason for this study is to construct and interpret geological cros-sections at depth to evaluate heat flow anomaly along the Yangsan fault. The Yangsan Fault passes through the south-eastern part of the Korean Peninsula. The cross-section is constructed from Sangbukmyeon to Unchonmyeon passing perpendicularly through the Yangsan Fault System trending NW-SE direction. The geological cross-section is constructed using the following data: (1) Lithologic distributions and main structural elements. (2) Extensity of sedimentary rock and igneous rock, from field mapping. (3) Fault dimension calculated based on geometry of exposed surface rupture, and (4) Seismic and core logging data. The Yangsan Fault System is composed of the Jain fault, Milyang fault, Moryang fault, Yangsan fault, Dongnae fault, and Ingwang fault which strike NNE-SSW. According to field observation, the western section of the Yangsan fault bounded by igneous rocks and in the eastern section sedimentary rocks are dominant. Using surface fault length we infer that the Yangsan Fault System has developed to a depth of kilometers beneath the surface. According to seismic data, sedimentary rocks that are adjacent to the Yangsan fault are thin and getting thicker towards the east of the section. In this study we also suggest a new method to recognize faults using core loggings. This analysis could be used to estimate fault locations at different scales.

Geomagnetic Depth Sounding to Investigate the Trend of Electrical Conductivity in and around the Korean Peninsula (지자기 수직 탐사에 의한 한반도 주변의 전기전도도 구조)

  • 오석훈;양준모;이덕기;남재철
    • Economic and Environmental Geology
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    • v.35 no.5
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    • pp.437-444
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    • 2002
  • Geomagnetic depth sounding (GDS) was performed to analyze the characteristics of deep resistivity structure in and around the Korean Peninsula. The data that have 0.01 nT precision were collected from 5 geomagnetic observatories and measured every one or five second. In this study, amount of 16 days of geomagnetic data were used for analyzing. Generally the sea affects the GDS data seriously due to its high conductivity. However, though the Korean peninsula is surrounded by seas in three sides, the results given by induction arrow strongly show that the trend of electrical conductivity at neighborhood of the Korean Peninsula is reigned by some geological features. Also it is believed that observation in Jeju island is related with the electrical structure around the East China Sea.