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Mode of Action of the Bacteriocan from Lactobacillus sp. GM7311 against Gram Negative Bacteria (Lactebacillus sp. GM7311이 생산하는 박테리오신의 Gram 음성균에 대한 작용형태)

  • KANG Ji-Hee;LEE Myung-Suk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.2
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    • pp.139-143
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    • 1999
  • The antimicrobial action of bacteriocin produced by lactobacillus sp. GM7311 against three Gram negative bacteria, Proteus mirabilis, Vibrio parahaemolyticus, and Escherichia coli, was investigated, When the bacteriocin was added to the culture at different stages, viable cells of all of the indicator strains tested were decreased, even though the most inhibited indicator cell growth stages were different. Transmission electron microscopic observation of indicator strains treated with bacteriocin revealed cell Iysis, indicating the cell membrane appears to be the primary site of action. The amino acids concentration of indicator strains treated with bacteriocin were diminished and fatty acids compositions were changed as compared with controls.

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Foundation Establishment of Professional Evaluation Center for Convergence of Energy Storage System (ESS) (에너지저장장치(ESS) 융복합 전문평가센터 기반구축)

  • Yoon, Yongho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.20 no.4
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    • pp.165-170
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    • 2020
  • In the rapidly growing new and renewable ESS parts and materials market, there is a limit for domestic SMEs to cope with the rapidly changing global new and renewable ESS market. There is a growing need to build a new and renewable ESS convergence commercialization support center. Therefore, through the establishment of a new and renewable ESS convergence professional evaluation center base, performance evaluation and standardization of new and renewable ESS products enhance product reliability. And By securing the reliability of new and renewable ESS, it is possible to promote domestic supply business and export activation. In addition, by supporting domestic research institutes and manufacturers to enhance their development capabilities and strengthen their competitiveness, and shortening the test cost and testing period according to the total-test evaluation system, it is possible anti-spill effect can be expected. Therefore, in this paper, we intend to study the establishment of a test certification center beyond the level of developed countries that can establish standardization for performance evaluation and demonstration.

A Study of evaluation methodology and basic data building to apply for the new renewable energy technology on the type of building (건축물의 유형별 신재생에너지 기술을 적용하기 위한 평가방안과 기초자료 구축에 관한 연구)

  • Choi, Jun-Ho;Kim, Yea-Sang
    • Korean Journal of Construction Engineering and Management
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    • v.14 no.2
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    • pp.108-116
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    • 2013
  • Recently, there is the growing concern about the environment and energy. Such concern has been seen in the field of building. In this study, Analysis was performed about a variety of techniques that can be applied to the building sector. By conducting a survey of expert, Characteristics of each technology and each Building types application are certificated. As a result, The application of renewable energy in buildings and determine the characteristics of each technology are presented. Based on these results, the selection method of the efficient technologies that take advantage of the building of the project from the planning stage are expected.

The Influence of Assay Error on Tobramycin Pharmacokinetics using the Nonlinear Least Square Regression and Bayesian Analysis in Gastric Cancer Patients (위암환자에서 비선형 최소자승 회귀분석과 베이시안 분석에 의한 토브라마이신의 약물동태에 분석오차의 영향)

  • Choi, Jun-Shik;Burm, Jin-Pil
    • Korean Journal of Clinical Pharmacy
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    • v.19 no.1
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    • pp.43-49
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    • 2009
  • 토브라마이신은 그람음성균 감염에 사용하는 아미노글리코사이드계 항생제로 이독성 및 신독성 등의 부작용과 큰 개인차로 혈중농도 모니터를 통한 투여계획이 필요한 약물이다. 본 연구에서는 16명의 위암환자에서 비선형 최소자승 회귀분석과 베이시안 분석에 의한 토브라마이신의 약물동태에 분석오차의 영향에 대하여 연구하였다. 약물투여는 토브라마이신 1-2 mg/kg을 30분에 걸쳐 8시간 간격으로 등속 주입하였으며, 혈액 채취는 정상상태에 도달되었다고 판단되는 첫 약물투여 72시간 후에, 약물 주입 5분전과 주입이 끝난 뒤 30분과 2시간에서 세차례 채취하였다. 혈청중 약물농도는 형광편광면역법으로 측정 하였다. 분석오차를 위해 0, 1, 2, 4, 8 및 12 ${\mu}g/mL$에 해당하는 토브라마이신 혈중농도(C)을 네차례 측정하여 각 혈중농도의 표준편차 (SD)을 구하였다. 토브라마이신 분석오차를 구하기 위한 다항식이 SD = 0.0224+0.0540C+0.00173C2, $R^2$ = 0.935이었다. 이 식에서 구한 SD 값으로 분석시 가중치를 주었을 때, 비선형 최소자승 회귀분석에 의한 토브라마이신의 약물동태학적 파라메타 ($V_d$, $K_{el}$, $K_{slpoe}$, $t_{1/2}$)에 유의성있는 영향을 주었으나, 베이시안 분석에 의한 토브라마이신의 약물동태학적 파라메타에는 영향이 없었다. 이 다항식으로 부터 구한 분석오차를 토브라마이신의 비선형 최소자승 회귀분석을 이용한 약물동태 연구 및 파라메타 분석에 적용하여 좀 더 정확한 투여용량을 결정할 수 있으며, 더 나아가 토브라마이신 약물동태 시뮬레이션 연구에 응용할 수 있다.

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Topic Model Analysis of Research Trend on Renewable Energy (신재생에너지 동향 파악을 위한 토픽 모형 분석)

  • Shin, KyuSik;Choi, HoeRyeon;Lee, HongChul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.9
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    • pp.6411-6418
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    • 2015
  • To respond the climate change and environmental pollution, the studies on renewable energy policies are increasing. The renewable energy is a new growth engine technology represented by the green industry and green technology. At present, the investments for the renewable energy supply and technology development projects of three main strategy sectors such as sunlight, wind power and hydrogen fuel cell are implemented in our country, while they are still in the early stage, accordingly reducing those uncertainty for the research direction and investment fields is the most urgent issue among others. Thus, this study applied text mining method and multinominal topic model among the big data analysis methods on our country's newspaper articles concerning the renewable energy over the last 10 years, and then analyzed the core issues and global research trend, forecasting the renewable energy fields with the growth potential. It is predicted that these results of the study based on information and communication technology will be actively applied on the renewable energy fields.

Argument Structure of Leibniz's Theodicy (라이프니츠 변신론의 논증 구조)

  • Lee, Nam-won
    • Journal of Korean Philosophical Society
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    • v.131
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    • pp.273-301
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    • 2014
  • This study aims to reconstruct Leibniz's theodicy. Theodicy is to defense of the highest wisdom of the creator against the charge which reason brings against it for whatever is the evil in the world. For this defense, Leibniz created his own new kind of concepts: the principle of sufficient reason, the principle of perfection, the best of all possible worlds, moral necessity. Leibniz's theodicy is developed as following. Most good and wisest God created this world freely by moral necessity. God's will was to choose the goods antecedently. But God's will could not create goods only. For God's final purpose is to create the best. For this reason, it happens that the evils may come about by concomitance, and as a result of other greater goods. Therefore the evils are necessary in the world. And evil consists in imperfection. Man has free will as God. Freedom, according to Leibniz, consists in intelligence, which involves a clear knowledge of the object of deliberation. Man has freedom, but man's freedom is imperfect. Evil is originated in man's imperfect freedom.

Trend Review of Solar Energy Forecasting Technique (태양에너지 예보기술 동향분석)

  • Cheon, Jae ho;Lee, Jung-Tae;Kim, Hyun-Goo;Kang, Yong-Heack;Yun, Chang-Yeol;Kim, Chang Ki;Kim, Bo-Young;Kim, Jin-Young;Park, Yu Yeon;Kim, Tae Hyun;Jo, Ha Na
    • Journal of the Korean Solar Energy Society
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    • v.39 no.4
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    • pp.41-54
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    • 2019
  • The proportion of solar photovoltaic power generation has steadily increased in the power trade market. Solar energy forecast is highly important for the stable trade of volatile solar energy in the existing power trade market, and it is necessary to identify accurately any forecast error according to the forecast lead time. This paper analyzes the latest study trend in solar energy forecast overseas and presents a consistent comparative assessment by adopting a single statistical variable (nRMSE) for forecast errors according to lead time and forecast technology.

Topic modeling and topic change trend analysis for advanced construction technologies (건설신기술에 대한 토픽 모델링 및 토픽 변화추이 분석)

  • Jeong, Seong Yun;Kim, Nam Gon
    • Smart Media Journal
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    • v.10 no.4
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    • pp.102-110
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    • 2021
  • Currently, the advanced construction technology endorsement system is being operated to promote the development of domestic construction technology. We tried to examine the implicit meanings inherent in advanced construction technologies by analyzing the relationship between emerging vocabularies with high importance in relation to the advanced construction technologies endorsed through this system. For this purpose, 918 cases of advanced construction technology information were collected. Based on the endorsed year and summary of the advanced construction technologies, the importance of the emerging vocabularies was measured for each advanced construction technology. And, based on the LDA model, the degree of influence between related vocabularies was evaluated for each of the four topic areas. Topics according to the technical application fields were analyzed. From 1990 to 2021, the trend of changes in highly influential vocabularies by each topic was inferred. In the future, changes in the degree of influence of the topics of environment, machinery, facilities, and maintenance and reinforcement of structures and related technology fields were predicted.

A Case Study on the New Administrative Capital Construction Records Management: Focusing on the Arquivo Publico do Distrito Federal of Brazil (신행정수도건설기록물 관리 사례 연구: 브라질의 ArPDF를 중심으로)

  • Gyeonghyeon, Park;Soonhee, Kim
    • Journal of Korean Society of Archives and Records Management
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    • v.22 no.4
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    • pp.109-128
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    • 2022
  • The new administrative capital construction project is an important national project implemented to relocate the national administrative capital, and the records produced during the construction have high historical value. However, Korea's management of these records related to the construction of the new administrative capital is insufficient; thus, finding a management plan is necessary. In contrast, Brazil is a country that collects, builds, and maintains both public and private records produced during the construction of Brasilia, the new administrative capital. Thus, Arquivo Publico do Distrito Federal (ArPDF), the Brazilian records management organization established to manage Brasilia's construction records, was selected as the case analysis subject in this study. By analyzing ArPDF's website and official publications, this study investigated the overall matters related to the management of new administrative capital construction records and derived implications applicable to the management of new administrative capital construction records in Korea.

Critical Review of Discourse on Aging in Korean Newspaper (대중매체에서의 신노년 담론 분석:신문매체를 중심으로)

  • Han, Gyounghae;Yoon, Sung-eun
    • 한국노년학
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    • v.27 no.2
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    • pp.299-322
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    • 2007
  • The purpose of this study is to critically review recent discourse on aging appeared in Korean newspapers. For this purpose, 1,725 articles on 'aging' or 'elderly' appeared on three major Korean newspapers during 1997- 2006 are analyzed. It is shown that there is a recent surge of articles portraying the positive images of aging in Korean newspapers emphasizing the importance of productive, successful aging and active life style of the elderly. This trend is a welcomed change from the negative images of elderly as dependent burden of society. However, it seems that over emphasis on positive aging and 'New Elderly' might have created another stereotype about the elderly and unintentionally marginalize the certain group of the elderly. By focusing on individual responsibility, it also overlooked the constraints imposed by social structure on disadvantaged elderly group, such as women, elderly in low socio-economic strata. Theoretical and policy implications of this trends are discussed.