• 혜화의학회지
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• 제8권1호
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• pp.727-738
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• 1999

Sintongchugoetang(CTCOT) is one of the importent prescription that has been used in oriental medicine(yyilimgaechak) for helling fractured condition. The study was done to evaluate effects of CTCOTwater extract on the tibia fractured rats. The result were obtained as follows : 1. In the change of X-ray, experimental group was significantly effected than control. 2. In the changes of body weight, experimental group was decreased than control. 3. In the change of Ca, P and ALP(alkaline phosphatase) on serum, all experimental group was not significant. 4. In the change of bone tissue, experimental group was was significantly effected than control in callus formation and maturity. From above results, CTCOT was had significant effects on the helling of fractured in rats, so it is expected to clinical application.

• 대한한방부인과학회지
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• 제33권1호
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• pp.104-115
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• 2020

Objectives: The purpose of this study is to discuss the differential diagnosis of postpartum pain. Methods: In this study, postpartum pain cases reported in the Journal of Korean Medicine were investigated, and a case of postpartum patient who diagnosed syringomyelia was reported. Results: Patients with autoimmune diseases who complained of postpartum pain had a different course of treatment process and they had related family history. Patients with syringomyelia also differed from the usual treatment process. Conclusions: In patients with postpartum pain who differ from usual treatment process, differential diagnosis of autoimmune disease and syringomyelia is necessary.

• 정보학연구
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• 제3권4호
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• pp.55-72
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• 2000

본 연구는 오늘날 국제금융 또는 국제건설공사거래 외에 매매대금의 지급을 위해 활용되는 보증신용장을 중심으로 하여 보증신용장의 본질과 보증신용장과 관련된 국제규칙을 분석한 다음, 보증신용장에 관한 신통일규칙의 제정배경과 규정된 내용 기존의 UCP와 URDG 등과 비교하여 이 규칙의 효용성과 활용상의 문제점들을 구체적으로 제시하였다.

• 대한한방부인과학회지
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• 제33권2호
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• pp.90-111
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• 2020

Objectives: The purpose of this study was to analyze randomized controlled trials (RCTs) related to the effect and safety of Korean Traditional Medicine treatment for postpartum pain, and to suggest desirable future clinical research trend. Methods: Randomized controlled trials (RCTs) on postpartum pain were searched using domestic and foreign search engines to investigate the effect and safety of Korean Traditional Medicine on postpartum pain, and 12 studies were selected as a result. Results: There were 4 studies using Acupoint Therapy, 3 studies using Herbal Medicine, 3 studies using Using Acupoint Therapy and Herbal Medicine together, and 2 studies using Manipulative Therapy for postpartum pain. As control interventions, non-treatment, other Korean Traditional Medicine treatment, or Western medicine were used. All the studies reported a significant effect in experimental group compared to the control group, with no or minor side effects. Conclusions: Korean Traditional Medicine treatment showed effectiveness and safety for postpartum pain. In the future, it is necessary to eliminate the ambiguity of recruiting subjects and to study the most effective application method of Korean Traditional Medicine treatment for postpartum pain.

• 대한한방부인과학회지
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• 제25권4호
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• pp.125-133
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• 2012

Objectives: Postpartum thyroiditis patient's symptoms are very similar to symptoms of postpartum disease which can be called sanhupung. This study is to report the effect of herbal medicine on sanhupung patient diagnosed of postpartum thyroiditis. Methods: We treated a 32-year-old female patient who had symptoms of postpartum thyroiditis and sanhupung with Jaeumganghwa-tang and Jayumkeonbi-tang. Results: After herbal medicine treatment the symptoms of postpartum thyroiditis such as general weakness, hot flush on the palms and soles of the feet, fever pattern of malaria and symptoms of sanhupung such as arthralgia, depression, imsomnia, sweating were improved. Conclusions: This case report shows that herbal medicine can be used to treat patient with postpartum thyroiditis and Jaeumganghwa-tang, Jayumkeonbi-tang is effective for mitigating the symptoms of postpartum thyroiditis. However, patient is still in thyroxine treatment, and additional care is required.

• 대한한방부인과학회지
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• 제23권4호
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• pp.109-116
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• 2010

Purpose: The purpose of this study was to examine Bone Marrow Density (BMD) of women suffering from general pain after childbirth. Methods: We studied 18 patients visiting $\bigcirc\bigcirc$hospital from March 2007 to May 2010. The subjects were categorized in two groups, symptom group(n=12) and no symptom group(n=6). We measured BMD using Dual Energy X-ray Absorptiometry (DEXA) and studied the difference of BMD between two groups by Student T-test using SPSS for windows(version 13.0). Results: The general characteristics such as age, days of postpartum, primiparity, cesarean section, breast-feeding of two groups were not different statistically. BMD, T-score and Z-score of symptom group were statistically lower than no symptom group. Conclusion: The results suggest that women suffering from general pain after childbirth shows low BMD, T-score and Z-score. It seems to be due to the kidney deficiency after childbirth.

• 대한한방내과학회지
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• 제18권1호
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• pp.69-85
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• 1997

This study was designed to elucidate the anti-inflammatory, cardiovascular, anti-thrombotic and analgesic effects of Shintongchugeotang. The anti-inflammatory effect was measured by the method of carragenin induced edema, protein leakage test using CMC-pouch, and the analgesic effect was measured by the acetic acid method and hot plate method, and the effect of Shintongchugeotang on the cardiovascular system was observed by the change of flow rate of Ringer solution in the vascular system in the ear of rabbit, and the contraction and dilatation of rat tail artery. Death rate, platelet aggregation, plasma coagulation activity was observed for the measurement of the anti-coagurative effect of Shintongchugeotang. The result was as follows : 1. After the administration of Shintongchugeotang extract, Carragenin induced edema and CMC-pouch protein leakage were significantly decreased. 2. The slight analgesic effect of Shintongchugeotang extract was confirmed by the observation of writhing syndrome, paw licking time, and escape time. 3. The drug increased the auricular blood flow in rabbit. 4. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 5. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 6. The drug inhibited the platelet aggregation in rat. 7. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable.

• 소음진동
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• 제5권3호
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• pp.292-302
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• 1995

압전재료를 이용한 능동진동제어에 관한 연구동향과 연구결과를 살펴보았다. 능동 진동제어에 사용되고 있는 감지기/작동기들 중 압전세라믹은 몇 가지 장점을 지니고 있어 그 적용에 관한 연구가 활발하게 진행되고 있는 것이 현실이며 실제 구조 물로의 적용이 이루어지고 있다. 압전세라믹을 이용한 진동제어는 박판으로 이루어진 국부구조물의 진동제어에 적합하며 그래서 자동차의 진동소음제어, 위성체 태양판의 진동제어에 사용할 수 있고 또한 겹쳐놓은 형태의 압전세라믹은 트러스 구조물의 능동 멤버로 활용할 수 있다. 이렇게 겹쳐놓은 압전세라믹 구조는 진동 고립(vibration isolation)을 원하는 장비의 지지대로 사용할 수 있어 그 응용분야가 넓다. 최근까지 도 압전세라믹을 이용한 진동제어는 주로 외팔보, 또는 평판과 같은 단순한 기하학적 형상을 가진 구조물에 국한되어 연구가 진행되어 왔고 제어기법 또한 그동안 전기 제어분야에서 개발되어 온 기법들을 적용하는 현상을 보였는데 구조물의 자유도가 무한대임을 고려할때 앞으로 구조물에 합당한 제어기법의 개발이 요망된다고 하겠다. 이 논문에서 선보인 PPF와 SRF 제어 기법은 필자가 간단히 회로를 구성하여 실험을 수행하였는데 압전재료의 진동제어 기법으로 단순하면서도 효율적인 제어기법이라고 말할 수 있다. 압전재료를 이용한 진동제어에 관한 국내의 연구활동이 미미한 상태 이으로 이분야에 대한 연구자들의 관심을 모을 필요가 있다. 압전세라믹 감지기와 작동기의 설치는 그동안 압전세라믹 판을 직접 구조물에 접착시킨 형태로 진행되었 는데 새로운 형태의 압전세라믹 작동기의 개발이 시급하다. 이는 높은 전압을 필요로 하는 진동제어는 필수적으로 커다란 부대시설을 요구하게 됨으로 전압을 높이지 않고 도 진동제어를 효율적으로 할 수 있는 압전세라믹의 제조가 필요하다고 하겠다. 필자 는 이런 목적으로 다층 압전세라믹(multilayer piezoceramic plate)을 제작한 적이 있었는데 실험결과는 신통치 않았다. 또한 압전세라믹을 길고 얇은 조각으로 잘라 사용하는 방법로 있었으나 세라믹의 절단시 다이아몬드 컷터를 사용해야 되어 제작이 곤란했다. 또한 압전세라믹이 부서지기 쉬운점을 개선한다면 진동제어에 있어 아주 효과적인 감지기/작동기가 될 수 있을 것이다.

• 대한한방내과학회지
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• 제22권4호
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• pp.557-565
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• 2001

Objectives : This study was carried out to examine toxic effect of Sintongchukeo-tang on cultured mouse spinal sensory neurons inhibited by neurotoxicity induced by hydrogen peroxide. Methods : MTT assay, NR assay, LDH and neurofilament assay were performed after spinal sensory neurons were preincubater with various concentrations of Sintongchukeo-tang water extract before treatment of cells with hydrogen peroxide. Results : Hydrogen peroxide induced ceil degeneration such as the decrease of cell viability was measured by MTT and NR assay in the cultured mouse spinal sensory neurons. Sintongchukeo-tang water extract was effective in the decrease of LDH activities of neurons produced by hydrogen peroxide. Sintongchukeo-tang water extract was effective in the increase of amount of neurofilaments damaged by hydrogen peroxide. Conclusions : From the above results, it is suggested that hydrogen peroxide induces the inhibition of cell viability in cultured mouse spinal sensory neurons and Sintongchukeo-tang water extract was effective in cultured neurons damaged by hydrogen peroxide.

• 한방재활의학과학회지
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• 제30권3호
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• pp.1-21
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• 2020

Objectives This study was designed to evaluate the bone regeneration effects of Sintongchukea-tang (SC) on rib fractured rats. Methods Rats were randomly divided into 5 groups (normal, control, positive control, SC low [SC-L] and SC high [SC-H]). All groups were subject to fractured rib except normal group. Normal group received no treatment at all. Control group was orally fed with phosphate buffered saline, and positive control group was medicated with tramadol (20 mg/kg). SC group was orally medicated with SC (50 mg/kg, 100 mg/kg) once a day for 14 days. The fracture healing process was observed by x-ray, micro CT and fracture tissue slide was observed by immunohistochemical staining. We analysed levels of transforming growth factor-β1, Ki67, alkaline phosphatase (ALP), runt-related transcription factor 2 (Runx2), receptor activator of nuclear factor kappa-β, tartrate resistant acid phosphatase (TRAP) and analysed levels of Osteocalcin in plasma. We measured levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), ALP, blood urea nitrogen (BUN) and creatinine in plasma, for hepatotoxicity and nephrotoxicity of SC. Results Though X-ray and micro-computed tomography, more callus formation was observed and bone union was progressing. Through Hematoxylin and Eosin, callus formation was increased compared to the control group. Runx2 level at SC-H was significantly increased and TRAP level at SC-L was significantly decreased compared with the control group. AST, ALT, ALP, BUN and creatinine were not statistically different from the control group. Conclusions As described above, SC promoted fracture healing by stimulating the bone regeneration factor. And SC shows no hepatotoxicity and nephrotoxicity. In conclusion, it seems that SC helps to promote fracture regeneration and it can be used clinically to patients with fracture.