• Journal of Digital Convergence
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• v.13 no.6
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• pp.225-234
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• 2015

Neurobiological approach helps to resolve the mind-body dualism and develop new assessment and treatment approaches in psychiatry. However, it could be a problem to place too much emphasis on certain aspects of neurobiology, specifically structural neuroanatomy, because of the complexity or comorbidity of neuropsychiatric disorders. Developmental Coordination Disorder (DCD), for instance, is generally related to problems in motor skills and this movement disability is often related to perception. One account, two visual systems theory, relied on functional distinction in brain; ventral stream is responsible for visual recognition, and dorsal stream is responsible for the guidance of actions. However, Studies are now showing that shape perception is relevant to visually guided action, such as reaching-to-grasp an object. In this article, I reviewed fundamental findings of two-visual system theory and suggested problems of visually guided action to consider what shape perception implies for the two visual systems. Questions raised highlight possible limitations of adopting a structural neuroanatomical approach to account for perception and action effects, and by extent related psychiatric conditions such as DCD. In conclusion, neurobiological approach converging to neuropsychiatry, while useful, would be limited if it focuses too much on anatomical distinction.

• The Science & Technology
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• s.474
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• pp.32-35
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• 2008

• The Science & Technology
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• v.33 no.10 s.377
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• pp.86-87
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• 2000

21세기를 주도하는 과학은 생물학으로 생명의 기원을 실험실에서 재생할 것이며 또 금속과 실리콘 신경과 근육이 함께 어우러져 일어나는 산업혁명이 시작될 것이다. 우리는 1백년 안에 소행성에 식민지를 건설하고 천년 후엔 인류도 다양하게 분화되며 1만년 단위로 보면 인간진화의 싸움터는 생물학에서 철학으로 옮겨갈 것이다.

• Korean Journal of Biological Psychiatry
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• v.8 no.1
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• pp.71-78
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• 2001

The current understanding of the neurobiology of anxiety is generally based on experimental animal model, empirical effective psychopharmacological agents, chemical and naturalistic challenge paradigms, and psychoendocinological assessment. This article focuses on reviewing neuroanantomical, neuroendocinological and neurofunctional research of anxiety disorder. In the decade ahead, we anticipate that extension of current research and the new integrated approach promise novel insight into mechanism of anxiety.

• The Science & Technology
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• v.35 no.7 s.398
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• pp.68-69
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• 2002

• Defense and Technology
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• no.12 s.190
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• pp.70-79
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• 1994

북한은 80년대 들어 신경가스등 화학작용제를 대규모 생산하면서 대포나 항공기에 실어 나를 수 있는 화학탄을 개발했고, 생물학전을 위해 세균연구 실험소 2곳과 연구시설 4곳을 갖추고 있는 것으로 알려져 있다. 더구나 96년 배치예정인 대포동 1호 등 장거리 탄도미사일에 장착할 경우 남한은 물론 동북아에 심각한 위협이 되고 있다. 이 글은 국방대학원 부설 안보문제연구소에서 개최한 국제안보학술토론회에서 영국의 마이클 시한 교수의 주제발표 내용이다.

• Mood & Emotion
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• v.10 no.1
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• pp.13-21
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• 2012

Suicide is a complex behavior associated with various neurobiological and psychosocial factors. It is considered that genetic polymorphism combined with environmental stress such as child-adolescent trauma make differences in neurobiological systems, which cause psychiatric disorders or pessimistic personality, impulse-aggressive behaviors, lack of judgment, and finally result in suicidal behavior. Much progress in the neurobiology of suicide has been made over the several decades. There seems to be a hereditary disposition to suicide independent of psychiatric disorder. The changes in neurotransmitters, neurohormones, neurotrophic factors, cytokines, lipid metabolisms related with their genetic polymorphism can contribute to disturbance of signal transductions and neuronal circuits vulnerable to suicide. It is likely that the main factors are dysfunctions of serotonin (5-HT) and hypothalamus-pituitary-adrenal (HPA) axis. Our understanding about the neurobiology of suicide is still limited. However, clinical practice could be assisted by neurobiological findings capable of making the detection of risk populations with higher sensitivity and the development of new treatment interventions. The settlement of biological markers in suicidal behaviors and their relationships is required.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.1
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• pp.3-15
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• 2001

The term 'memory' has acquired so many meanings today that it is not even confined to the mental domain any longer, although it is etymologically derived from the Anglo-Saxon word 'gemund', meaning mind. In its most typical sense, memory can be defined as 'the reawakening of the past in the service of present'. But in many papers, the term memory has been used in a various different meaning, which made the interpretation of the research result very complicated. Recently there has been tremendous development in the neurobiological researches with regard to the memory. This paper reviewed the concept, history, and current tendencies of the memory and memory researches comprehensively for the purpose of showing future direction of the memory researches.

• Electronics and Telecommunications Trends
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• v.9 no.4
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• pp.53-61
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• 1994

최근 생물학에 기반을 두고 최적화 문제와 학습 문제에 많이 사용되고 있는 유전자 알고리즘과 신경 회로망 기술을 결합하는 연구가 활발해 지고 있다. 신경 회로망 연구에 비해 조금 늦게 시작된 유전자 알고리즘에 대한 연구는 유전자 복제, 교차, 돌연 변이 등의 현상을 걸쳐서 새로운 개체를 발생시켜 나가는 진화의 과정에서 착안하여 해결하고자 하는 문제의 해답을 유전자 탐색의 과정을 통하여 찾아내는 것이다. 이 글에서는 유전자 알고리즘과 신경 회로망을 혹은 서로 보조적인 입장에서 혹은 동등한 입장에서 결합하는 연구에 대한 조사를 소개함으로써 보다 복잡한 최적화 문제나 자동 프로그래밍, 기계 학습, 복잡한 자료 분석, 시계열 예측 등의 분야에 응용하는데 도움을 주고자 한다.

• Korean Journal of Biological Psychiatry
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• v.20 no.3
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• pp.74-79
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• 2013

Objectives This paper aims to understand the emotional-biological pathogenesis of eating disorders, and translate the understanding into new brain directed treatments. Methods The first part of the review sets the eating behavior into the context of what is now understood about the central control of appetite and molecular biology. The second part of the review sees how emotion relates to the brain circuit involving eating disorders. Results In general, patients with anorexia nervosa restricting type were less sensitive to reward, whereas patients with bulimia nervosa and anorexia nervosa binge purging type were more sensitive to it. The emotional life of people with eating disorders centers on food, weight, and shape. The abnormalities in social and emotional functioning both precede and persist outside of eating disorders. Conclusions Research into understanding the biological framework of the brain in eating disorders suggests that abnormalities may exist in emotional and information processing. This aspect can be translated into novel brain-directed treatments, particularly in anorexia nervosa.