• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2013.10a
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• pp.435-437
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• 2013

문화자원으로서의가치를내재하고, 접근성이양호한 등대 중일부를 문화교육시설, 공공편의시설 등을 확충하여 등대해양문화공간으로 지정(운영)하고 있으나, 지역(등대)별 해양문화 공연 프로그램의 획일화 등에 따른 집객효과 저조로 다양한 문화컨텐츠 도입이 필요하며, 지자체 등 유관기관과의 협업을 통한 해양관광 개발 등 시너지 효과를 극대화 하기 위한 방안을 연구하였다.

• Defense and Technology
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• no.5 s.255
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• pp.18-25
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• 2000

T-50은 제 3세대 훈련기의 특징을 최대한 살려서 Total Traing System으로서의 가치를 높여야 한다. 즉, 항공기 뿐만 아니라 비행시뮬레이터를 비롯한 각종 지상비행훈련장비와 정비훈련장비 등으로 Total Traing System으로서의 시너지 효과를 높이는데 주력해야 할 것이다. 또한 KT-1과 조화롭게 연계된 비행훈련체계를 구축함으로써 세계 훈련기시장에서 제 3세대 훈련기의 선두주자로서의 인식과 함께 마케팅에도 상호보완효과를 유도해 낼 수 있을 것으로 예상된다. 이제 세계 훈련기 시장의 종주국으로 거듭나고 있는 한국의 항공산업은 때마침 구조조정에 의해 새로 탄생된 한국항공우주산업(주)의 출범과 맞물려 세계 항공업계의 주목을 받기 시작했다.

• Korean Journal of Food Science and Technology
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• v.48 no.3
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• pp.241-246
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• 2016

The object of this study was to develop an alternative way to treat human skin pathogens using marine algae. During this study, we observed that the ethanolic extract of the edible brown algae [Sargassum serratifolium (C. Agardh) C. Agardh] exhibited potential antimicrobial activity against pathogenic commensal bacteria related with acne vulgaris (Propionibacterium acnes, Staphylococcus epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa), and Candida albicans which causes cutaneous candidiasis. Among the solvent-soluble fractions from the ethanolic extract, a hexane-soluble fraction showed the strongest antimicrobial activity against all tested human skin pathogens with MIC values ranging from 32 to $512{\mu}g/mL$. In addition, the hexane fraction exhibited a synergistic antimicrobial activity with commercial antibiotics used in the treatment of acne vulgaris or cutaneous candidiasis. Thus, this study suggests that S. serratifolium extract could be a potential source of natural antimicrobial agents or a pharmaceutical component against human skin pathogens.

• Journal of Applied Biological Chemistry
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• v.52 no.3
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• pp.116-120
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• 2009

We found out the new method of the consortium for the environmental friendly agriculture by 8 kinds of the selected antagonistic rhizobacteria. This research involved composition of mutual complementary consortium by each antagonistic function such as production of antibiotic, siderophore, antifungal cellulase and insoluble phosphate solubilization. The consortium No.11 among composed consortium candidates showed the most pepper growth promoting activity and Phytophthora blight suppression on the in vivo pot test of red-pepper plant. The consortium No. 11 is combination of PGPR Bacillus subtilis AH18 and Bacillus licheniformis K11. B. subtilis AH18 and B. licheniformis K11 both could produce the auxin, antifungal ${\beta}$-glucannase and siderophore. Also, they had mechanism for solubilization of insoluble phosphate. But, B. licheniformis K11 could produce the antibiotic of iturin which was able to inhibit Phytophthora capsici. We confirmed complementary noncompetitive mutualism between B. subtilis AH18 and B. licheniformis K11 of the consortium No.11. The results came out through treatment of two strains co-culture, treatment of individual culture and co-treatment of two individual cultures for the growth and Phytophthora blight suppression of red-pepper. The treatment of two strains co-culture didn't show a synergic effect in comparing sole treatment on the pepper growth promotion and Phytophthora blight suppression. But, when the pots were treated simultaneously with co-treatment of two individual cultures, an synergic effect was seen in the growth promotion of roots, stem, leaves and suppressed Phytophthora blight on red-pepper in vivo pot test.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.3
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• pp.229-235
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• 2015

Skin aging is the phenomena finally expressed on the skin surface and related to the changes in the microstructure of the skin texture. Which is resulted in wrinkle formation and uneven tone of skin and so on. In this study, the synergy effect of Cedrol and a collagen-derived peptide in type III collagen synthesis was evaluated by in vitro test. The physiological skin state of 22 female volunteers was measured after using the cosmetics for 4 weeks. Results showed that Cedrol and a collagen-derived peptide had the excellent synergy effect in type III collagen synthesis. The cosmetics improved skin microrelief, star configurations, skin gloss, skin tone, hydration and elasticity except skin lightening. In conclusion, this study proved that Cedrol and collagen-derived peptide had the synergy effect of type III collagen synthesis in the cell level and cosmetics with those was improved skin aging in human volunteer test.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.8
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• pp.823-830
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• 2008

The feasibility study for the application of the photoelectrocatalytic decolorization of Rhodamine B(RhB) was performed in the slurry photoelectrochemical reactor with powder TiO$_2$. The photoelectrocatalytic process was consisted of powder TiO$_2$, Pt electrode and three 8 W UV-C lamps. The effects of operating conditions, such as current, electrolyte, air flow rate and electrode material were evaluated. The experimental results showed that optimum TiO$_2$ dosage and current in photoelectrocatalytic process were 0.4 g/L and 0.02 A, respectively. It was found that the RhB could be degraded more efficiently by this photoelectrocatalytic process than the sum of the two individual oxidation processes(photocatalytic and electrolytic process). It demonstrated a synergetic effect between the photo- and electrochemical catalysis. Photoelectrocatalytic process was affected to air flow rate and optimum air flow rate was 2 L/min. The electrode material and NaCl effect of decolorization of RhB were not significant within the experiment conditions.

• Journal of Food Hygiene and Safety
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• v.28 no.4
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• pp.354-359
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• 2013

This study was performed to elucidate the antioxidative and antiaging activities of mixed rates 2:6:2(262), 6:2:2(622) and 4:4:2(442) of fermented soybean, fermented rice bran, fermented red ginseng based on the comparision with their separate results of our three previous studies. The antioxidative and antiaging effects of 262, 622 and 442 mixed ratios were evaluated by the determination of superoxide radical scavenging activities, hydroxy radical scavenging activities, linoleic acid inhibition activtiy, elastin synthesis activity, and cell viability of B16F10. The material of 442 ratio showed the higher effects than those of 262 and 622 ratios, and presented the higher effect than the separate material of red ginseng in the antioxidative and antiaging activities. Therefore, this study suggested that the material of 442 ratio in the production of red gineng-containing cosmetics could be preferred as a useful cosmetic ingredient for antioxidation and antiaging.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.271-282
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• 2019

The purpose of this study is to identify the antimicrobial effects of SSH(三神丸) and synerggy effects of the existing antibiotics Oxacillin and Ciprofloxacin on MRSA and to identify the mechanisms. In this case, the procedure and method for verifying anti-bacterial activity and active concentration of MARA by measuring the minimum inhibitory concentration (MIC) of the trichin is used to verify the potency and active concentration of MARA, to confirm the potency of the disease by treating antibiotics and trichine ethanol extract in parallel, and to confirm the anti-bacterial effect over time, when the trichine is activated as an anti-bacterial activity to MARA, and a compound. In addition, we hope that this research will not only serve as meaningful data for the development of new drugs to control MARA immunity, but also serve as an opportunity to further accelerate the research and development of antibiotics to overcome resistant strains.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.2
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• pp.155-161
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• 2021

This study was attempted to investigate natural materials with antimicrobial activity and to apply as natural preservatives in cosmetics. The disc diffusion method was used to search for nine species of natural antibacterial material for three species of skin pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa) and Candida albicans. As a result of measuring the size of inhibition zone, Rhus Semialata gall (Gallnut) extract, Oak vinegar, and ε-polylysine were showed strongest antibacterial activities (> 10 mm). The Minimum Bactericidal Concentration (MBC) of gallnut and oak vinegar ranged from 10 to 20 mg/mL and from 20 to 40 mg/mL against five human skin pathogens. The MBC of ε-polylysine ranged from 0.5 to 2 mg/mL in fungus. The synergic effect of gallnut extract/oak vinegar mixture and gallnut extract/ε-polylysine mixture were evaluated by checkerboard test. Compared to when used alone, the MBC of gallnut extract/oak vinegar mixture were at 4 times lower concentration against E. coli, C. albicans, and A. brasiliensis. Also Furthermore, the MBC of gallnut extract/ε-polylysine mixture were at 4 times lower concentration against C. albicans and A. brasiliensis. It was confirmed that the combination of gallnut extract with oak vinegar or ε-polylysine resulted in synergistic antibacterial effect against three human skin pathogens. Thus, it is expected that gallnut extract and natural product mixture can not only demonstrate antibacterial synergies, but also be applied in cosmetics as a natural preservative system with a wide antibacterial spectrum.

• Journal of radiological science and technology
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• v.37 no.1
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• pp.21-28
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• 2014

Cultured pancreatic beta cells and nerve cells, it is given normal condition of 10% FBS (fetal bovine serum), 11.1 mM glucose and hyperglycemia codition of 1% FBS, 30 mM glucose. For low LET X-ray irradiated with 0.5 Gy/hr dose-rate(total dose: 0.5 to 5 Gy). Survival rates were measured by MTT assay. When non irradiated, differentiated in the pancreatic beta cells experiment is hyperglycemia conditions survival rate compared to normal conditions survival rate seemed a small reduction. However increasing the total dose of X-ray, the survival rate of normal conditions decreased slightly compared to the survival rate of hyperglycemia conditions, the synergistic effect was drastically reduced. When non irradiated, undifferentiated in the nerve cells experiment is hyperglycemia conditions survival rate compared to normal conditions survival rate seemed a large reduction. As the cumulative dose of X-ray normal conditions and hyperglycemia were all relatively rapid cell death. But the rate of decreased survivals by almost parallel to the reduction proceed and it didn't show synergistic effect.