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Anti-aging Effects of Cedrol and Collagen-derived Peptide

세드롤과 콜라겐 유래 펩타이드의 피부노화 개선효과

  • Ryu, Jong Seong (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Cho, Hwan Il (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Won, Ji Hee (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Jeon, Mi Na (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Kwon, Oh Sun (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Won, Bo Mi (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Lim, Jun Man (Skin Research Center, Research Park, LG Household & Healthcare Ltd.) ;
  • Lee, Sang Hwa (Skin Research Center, Research Park, LG Household & Healthcare Ltd.)
  • 류종성 (LG 생활건강 기술연구원) ;
  • 조환일 (LG 생활건강 기술연구원) ;
  • 원지희 (LG 생활건강 기술연구원) ;
  • 전미나 (LG 생활건강 기술연구원) ;
  • 권오선 (LG 생활건강 기술연구원) ;
  • 원보미 (LG 생활건강 기술연구원) ;
  • 임준만 (LG 생활건강 기술연구원) ;
  • 이상화 (LG 생활건강 기술연구원)
  • Received : 2015.08.01
  • Accepted : 2015.09.23
  • Published : 2015.09.30

Abstract

Skin aging is the phenomena finally expressed on the skin surface and related to the changes in the microstructure of the skin texture. Which is resulted in wrinkle formation and uneven tone of skin and so on. In this study, the synergy effect of Cedrol and a collagen-derived peptide in type III collagen synthesis was evaluated by in vitro test. The physiological skin state of 22 female volunteers was measured after using the cosmetics for 4 weeks. Results showed that Cedrol and a collagen-derived peptide had the excellent synergy effect in type III collagen synthesis. The cosmetics improved skin microrelief, star configurations, skin gloss, skin tone, hydration and elasticity except skin lightening. In conclusion, this study proved that Cedrol and collagen-derived peptide had the synergy effect of type III collagen synthesis in the cell level and cosmetics with those was improved skin aging in human volunteer test.

피부 노화는 피부 표면에 나타나는 현상으로 피부 표면의 미세구조와 연관이 있다. 피부 미세구조의 변화는 주름형성, 피부 톤 저하 등 다양한 피부 노화 현상을 유발하는 요인이 된다. 본 연구는 주름 기능성 성분인 세드롤(Cedrol)과 콜라겐 유래 펩타이드 성분을 이용하여 시험관 수준(in vitro)에서 타입III 콜라겐 합성 시너지 효과를 평가하였다. 여성 피시험자를 대상으로 4주 동안 상기 원료가 함유된 크림제품을 사용한 후 피부 미세구조, 스타 형상(star configurations), 보습, 탄력, 피부 밝기, 윤기, 피부 톤, 투명도를 평가하였다. 시험관 수준의 세드롤과 펩타이드를 동시에 처리하면 우수한 수준의 타입III 콜라겐 합성 시너지효과를 나타내었다. 그리고 크림제형을 이용한 인체적용 시험에서는 사용 4주 후부터 피부 미세구조, 스타형상, 윤기, 피부 톤, 보습, 탄력을 개선시켰으나, 피부 밝기 개선 효능은 나타나지 않았다. 본 연구를 통하여 기존 주름 기능성 성분인 세드롤과 콜라겐 유래 펩타이드는 세포 수준에서 타입III 콜라겐 합성 시너지 효과가 있음을 확인하였고 이를 화장품에 적용하여 시험한 결과 피부 노화 개선에 도움을 주는 성분임을 확인하였다.

Keywords

References

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