• Korean Journal of Schizophrenia Research
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• v.23 no.1
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• pp.15-28
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• 2020

Objectives: This study investigated the relationship between clock-drawing test (CDT) performance and neuropsychological functions in patients with chronic schizophrenia. Methods: Thirty-one patients with schizophrenia and 30 healthy controls participated in this study. The CDT was administered in three conditions and analyzed using both quantitative and qualitative scoring systems. Comprehensive neuropsychological tests were administered. Results: The results of the quantitative analysis showed that the schizophrenia group performed significantly worse in all three conditions of the CDT compared with the control group. However, no significant differences were observed between the two groups, when the IQ and educational level were controlled. The qualitative analysis showed that the schizophrenia group exhibited significantly more errors in "graphic difficulty" compared with the control group. In addition, CDT quantitative scores were significantly correlated with visuospatial function, memory, attention and executive functions in patients with schizophrenia. Conversely, each qualitative error type was correlated with specific cognitive domains. Furthermore, "graphic difficulty" and "spatial/planning deficit" were identified as predictors of depression symptoms in patients with schizophrenia. Conclusion: The present study demonstrated that the CDT is useful for assessing cognitive dysfunctions in patients with schizophrenia, while qualitative analyses provide more specific information about cognitive deficits compared with quantitative analyses.

• Sleep Medicine and Psychophysiology
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• v.27 no.1
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• pp.16-23
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• 2020

Objectives: Sleep disturbance in the elderly is associated with cognitive decline. Sleep quality is known to deteriorate with age, and prospective studies seldom have examined the relationship between sleep quality and cognitive function. This study investigates the relationship between early sleep quality and cognitive function based on six-year follow-up data of community individuals older than 60 years. Methods: The participants included 622 community elderly people older than 60 years from Jinju-Si. The final analysis comprised 322 elderly people. Pittsburgh sleep quality index (PSQI) and the Korean version of Consortium to Establish a Registry for Alzheimer's Disease (CERAD-K) were used to assess early sleep quality and cognitive function after six years. Multiple linear regression analysis was performed to investigate the association between early sleep quality and cognitive function in the elderly. Results: Early sleep quality (PSQI) was significantly associated with the results of the digit span test, clock drawing test (clox 1), and word recall test after six years. Sleep quality (PSQI) decreased significantly after six years, and lower quality of sleep (PSQI) score was associated with higher digit span test score (β = -0.167, p = 0.026) and higher clock drawing test score (β = -0.157, p = 0.031). Lower quality of sleep (PSQI) score was associated with higher word recall test (β = -0.140, p = 0.039). Conclusion: The digit span test, word recall test, and clock drawing task (CLOX 1) shown to be significantly associated to sleep quality can be performed fast and easily in clinical practice. It is important to assess early cognitive function in the elderly with poor sleep quality, and further studies could suggest that these tests may be useful screening tests for early dementia in elderly with poor sleep quality.

• 한국노년학
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• v.40 no.2
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• pp.325-340
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• 2020

Early diagnosis and intervention of dementia is critical to minimize future risk and cost for patients and their families. The purpose of this study was to develop and validate Figure-Copy Test(FCT), as a new dementia screening test, that can measure neurological damage and cognitive impairment, and then to examine whether the grading precesses for screening can be automated through machine learning procedure by using FCT imag es. For this end, FCT, Korean version of MMSE for Dementia Screening (MMSE-DS) and Clock Drawing Test were administrated to a total of 270 participants from normal and damaged elderly groups. Results demonstrated that FCT scores showed high internal constancy and significant correlation coefficients with the other two test scores. Discriminant analyses showed that the accuracy of classification for the normal and damag ed g roups using FCT were 90.8% and 77.1%, respectively, and these were relatively higher than the other two tests. Importantly, we identified that the participants whose MMSE-DS scores were higher than the cutoff but showed lower scores in FCT were successfully screened out through clinical diagnosis. Finally, machine learning using the FCT image data showed an accuracy of 73.70%. In conclusion, our results suggest that FCT, a newly developed drawing test, can be easily implemented for efficient dementia screening.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.191-199
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• 2021

This study aims to present the need to supplement the driver's license renewal test for elderly drivers. In Korea, the proportion of elderly drivers is increasing as the elderly population increases rapidly. Overall the traffic accident rate is decreasing but the traffic accident and death rate from traffic accidents are increasing in older drivers. In this study the assessments and education conducted when renewing the driver's license for elderly drivers conducted in Korea were conducted to find out the necessary tests compared to the current situation of foreign countries. Although it is appropriate to evaluate the three key functional areas of vision, cognition, motor and somatosensory, we currently evaluate visual acurity in vison area. While MMSE-K and Clock drawing tests are not recognizable for mild cognitive impairment in cognitive areas. The motor and somato sensory function to perform driving are not evaluated at all. Therefore for safe driving of older drivers, the test to be conducted during renewal of the driver's license will need to supplement that the visual field and contrast sensitivity in vision area, cognitive function from mild cognitive impairments, and the endurance, functional range of motion and proprioception in motor function area.

• Journal of Oriental Neuropsychiatry
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• v.12 no.2
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• pp.185-191
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• 2001

Objectives: This study aimed to evaluate the usefulness as a screening test of Clock Drawing Test(CDT) compared with the standard K-DRS in probably dementia. Methods: The subjects for this study consisted of 19 elderly persons who visited to the outpatient department of Oriental Neuropsychiatry of the Kyunghee Oriental hospital. They received the K-DRS and the Clock Drawing Test. Three observers evaluated them with circle, numbers, hands. Inter-rater reliability of scores from Clock Drawing Test was assessed and Pearson correlation coefficients were used to examined the relationships between scores from Clock Drawing Test and K-DRS. Results: Correlations between individual raters was highly significant (r= .957, .974, and .970, respectively: p<.001). There was stastically significant correlations between K-DRS and CDT scores (r= 0.849, p<.001). Conclusions: The CDT can be rated reliably by observers and correlations between CDT and K-DRS is significantly high. We confirmed the usefulness of CDT as simple, easily administered, low cost, and reliable general screening test for dementia.

• Therapeutic Science for Rehabilitation
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• v.3 no.1
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• pp.67-77
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• 2014

Objective : The purpose of this study was to examine task-oriented training affects on instrumental activity of daily living for elderly with dementia. Methods : The participant is a 75 years old female with dementia. The intervention was performed for 45 minute on 3 times per week over 1 month. Independent variable was task-oriented training and dependent variable were memory(DST), executive function(TMT-A, CDT), changing of IADL(AMPS). Results : The results showed that the participant significantly improved in executive function, performance of IADL. However, the participant did not show significant improvement in memory. Conclusion : In conclusion, the findings of this study indicate that task-oriented training is positive effect on performance of IADL in dementia.

• The Journal of the Korea Contents Association
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• v.13 no.5
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• pp.322-331
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• 2013

The aim of this study was to investigate the effects of occupational therapy with physical exercise on executive function with dementia. For eight elderly persons with mild or moderate dementia, we executed physical exercise with group activity for 10 weeks from April to June, 2012, one times per week, and 50 minutes each time. Before and after the physical activities, the old adults were tested with Verbal Fluency Test(VFT), Trail Making Test A/B(TMT A/B), Clock Drawing Test(CDT). After the physical exercise, the subjects showed significant changes in the score of CDT(p<0.1). In contrast, there was no significant effect in VFT, TMT A. The results of this study show that occupational therapy with physical exercise program for demented elderly people is a useful therapeutic approach by enhancing the their quality of life through improving and maintaining their executive function.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3344-3352
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• 2015

The purpose of this study is to investigate the effects of Korean computer-based cognitive rehabilitation program (CoTras) on frontal-executive functions in patients with traumatic brain injury (TBI). This study was performed at C hospital in Changwon, Gyeongsangnam-do, Korea from August 2013 to March 2014. Ten patients with TBI were randomly divided into two groups. The experimental group had been given CoTras once a day, five times a week for four weeks, whereas the control group had performed self-cognitive training under the same conditions. To verify the effect of intervention, the following executive function measures were used: Korean Montreal Cognitive Assessment (K-MoCA), Executive Clock Drawing Test (ECDT), Trail Making Test (TMT), Rey-Complex Figure Test (RCFT). Intervention group showed significant increase in K-MoCA, TMT, RCFT-delayed recall (p<.05). However, control group showed no significant change in any test. There was significant difference of changed scores (post test-pre test) between two groups in K-MoCA, TMT and RCFT-delayed recall (p<.05). This study showed that CoTras is effective to improve frontal-executive functions in patients with traumatic brain injury.

• Sleep Medicine and Psychophysiology
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• v.20 no.1
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• pp.15-21
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• 2013

Objectives: Cognitive impairment in restless legs syndrome (RLS) patients can be affected by sleep deprivation, anxiety and depression, which are common in RLS. The objective of this study is to investigate relationship between cognitive impairment and RLS in the non-medicated Korean elderly with controlling for psychiatric conditions. Method: The study sample for this study comprised 25 non-medicated Korean elderly RLS patients and 50 age-, sex-, and education- matched controls. All subjects were evaluated with comprehensive cognitive function assessment tools- including the Korean version of Consortium to Establish a Registry for Alzheimer's Disease Assessment Packet (CERAD-K), severe cognitive impairment rating scale (SCIRS), frontal assessment battery (FAB), and clock drawing test (CLOX). Sleep quality and depression were also assessed with Pittsburgh sleep quality index (PSQI) and geriatric depression scale (GDS). Results: PSQI and GDS score showed no difference between RLS and control group. There was no significant difference between two groups in nearly all the cognitive function except in constructional recognition test, in which subjects with RLS showed lower performance than control group (t=-2.384, p=0.02). Subjects with depression ($GDS{\geq}10$) showed significant cognitive impairment compared to control in verbal fluency, Korean version of Mini Mental Status Examination in the CERAD-K (MMSE-KC), word list memory, trail making test, and frontal assessment battery (FAB). In contrast, no difference was observed between subjects who have low sleep quality (PSQI>5) and control group. Conclusions: At the exclusion of the impact of insomnia and depression, cognitive function was found to be relatively preserved in RLS patients compared to control. Impairment of visual recognition in RLS patients can be explained in terms of dopaminergic dysfunction in RLS.