• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.78-78
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• 2015

조기에 홍수 위험을 예측하고, 빠르게 이동 또는 진화하는 강수 사상을 추적하기 위해서는 높은 시간 해상도의 실시간 강우 생산이 필요하다. 레이더는 순간 강우강도를 측정하기 때문에, 긴 시간 간격의 관측 주기는 빠르게 움직이는 폭풍의 레이더 QPE에 상당한 샘플링 오차가 발생하기 쉽다. 따라서 본 연구에서는 레이더 관측주기에 따른 강우량의 정량적 차이에 대한 검증을 실시하였다. 본 검토는 2013-2014년 한국건설기술연구원(KICT) X-Band 이중편파레이더로 관측된 사상을 대상으로 하였다. 최소 관측주기(관측전략에 따른 최소 관측주기)를 토대로 샘플링을 하여 긴관측주기 자료를 생산하였다. 비교결과, 약 5분 관측주기에서도 5 % 이상의 차이를 보이는 경우가 상당수 있었다. 이 결과를 토대로 보면 도시홍수 관측을 위해서는 대략 1-2분 정도의 관측주기를 유지해야 하는 것으로 나타났다.

• Journal of radiological science and technology
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• v.40 no.2
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• pp.213-218
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• 2017

Recently, as the number of high-risk pregnancies increases, the use of new techniques such as Doppler, which have higher acoustic power than in the past, has been increasingly used in prenatal diagnosis and guidelines have been set up by various organizations to prevent excessive exposure. Therefore, in this study, we tried to investigate the temperature change of the body surface for each test mode according to the long time ultrasound examination and to examine the exposure time which is not influenced by the thermal effect. B mode, C mode, and PD mode according to time, and the temperature difference between exposed and unexposed sites were compared. As a result, the B mode showed a significant difference in the temperature change from 10 minutes, 50 minutes after exposed, 20 minutes from the C mode, and 30 minutes from the PD mode (p<0.01). In all three modes, the temperature difference was different (p<0.000), and PD mode was the most sensitive to temperature change. Also, it was found that the temperature rise time was shortened with the increase of the ultrasonic exposure time. Therefore, it is recommended that ultrasonography to observe the embryo or fetus should be used only for diagnostic purposes, avoiding excessive test time.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.235-239
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• 1996

In recent years, the optical properties of multiple-scattering media like tissue have been studied for their potential applications in medicine. In this work the optical properties of multiple scattering media were investigated using the time-resolved reflectance measurement. The reflected light was measured by time-correlated single photon counting system. The transport scattering and absorption coefficient are related to the initial rapid decay and the subsequent decay in reflected light, respectively. Also the optical properties of the samples were measured by conventional method, ie., using continuous wave light. When the distance between the light source and the detector is over 8mm, the optical coefficient can be measured accurately using the suggested method.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2006.05a
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• pp.170-174
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• 2006

근육 단백질과 우유 단백질간의 상호작용의 촉매제로써 TGase의 최적화를 위한 온도와 배양시간을 결정하고자 본 실험을 실시하였다. 돼지 등심에서 근원섬유 단백질을 추출하였고 배양온도는 4, $37^{\circ}C$로, 배양시간은 0, 0.5, 2, 4시간으로 설정하였다. 단백질의 열량분석, 점도, 겔 강도, 단백질 밴드의 변화를 측정하였으며, 그 결과 단백질 열량 변화는 각 단백질 별로 열량 변화 패턴이 상이하게 나타났으며 근원섬유와 카제인 염의 혼합액은 각각의 단백질의 피크와 유사하게 나타났고 배양시간과 온도에 따라 차이를 보여 $4^{\circ}C$에 비하여 $37^{\circ}C$에서 열량 변화가 크게 나타났다. 점도의 경우 배양하지 않은 것과 비교했을 때 $37^{\circ}C$에서 2시간 배양했을 때부터 유의적인 차이를 보이며 증가했으나 4시간 배양한 것과는 차이를 나타내지 않았다. 전기영동의 경우에도 $37^{\circ}C$에서 30분 배양한 처리구는 큰 변화를 나타내지 않았으나 2시간부터 저분자의 밴드가 소멸되고 고분자의 biopolymer를 형성되었다.

• Journal of fish pathology
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• v.20 no.2
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• pp.139-145
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• 2007

To decrease stress in eel (Anguilla japonica) during its culture or transportation, aspirin (ASA) known as analgesic, antiinflammatory and antithrombic agent was administrated by dipping or oral routes. Concentrations of aspirin (ASA) and salicylic acid (SA) in eel plasma were simultaneously measured by a high performance liquid chromatography (HPLC). The plasma was acidified with 0.2 M HCl and 0.2 M orthophosphoric acid, and mixed with acetonitrile. ASA and SA extracted with acetonitrile were analyzed by the HPLC equipped with reversed phase Novapak C18 column (4 ㎛ silica, 150×4 mm) and UV detector(237 nm). The mobile phase consisted of 740 ㎖ water, 900 ㎕ orthophosphoric acid (85%) and 180 ㎖ acetonitrile. The retention times of ASA, SA and 2-methylbenzoic acid(MBA) were 4.8 min, 8.4 min and 11.5 min, respectively. The limit of quantification was 0.01 ㎍/㎖ for SA and 0.05 ㎍/㎖ for ASA. The mean recovery from eel plasma was 70.8～99.6% for ASA and 95.2～100.3% for SA. This HPLC method was applied to analyze ASA and SA of eel plasma after either dipping in a concentration of 20 ppm or feeding the feed supplemented with 50 ㎎/kg BW. Only SA was detected in eel plasma after the administration of ASA by dipping or oral routes because the drug was quickly decomposed into SA in eel plasma. The amount of SA in eel plasma reached the highest value at 3hr in dipping and 7 days in oral administration. When the ASA-administrated eel were kept in ASA free aquaria, 0.02-0.03 ㎍/㎖ of SA were detected 48 hr after the administration in both routes.

• Progress in Medical Physics
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• v.6 no.2
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• pp.61-70
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• 1995

The picosecond time resolved fluorescence spectra of Hematoporphyrin Derivative (HPD) in both solutions and cancer cell are measured by a time correlated single photon counting system with a synchronously mode locked dye laser. Two exoponential decay components in the fluorescence spectra were observed. The slow decay(6.3 ㎱)and the fast one(350 ㎰)are attributed to be originated from monomers and dimers, respectively. The absorption and fluorescence measurements in steady state also showed the presence of a monomeric and dimeric forms of HPD molecules. The monomer lifetime in the cancer cell was measured to be longer than that in solution, which was expected from the blue shift and narrowing of the absorption spectra for HPD-treated in vitro. The relative amplitude of the fast component was found to be enhanced in cancer cell, strongly indicating the higher affinity of the dimer for the cancer cell.

• Korean Journal of Animal Reproduction
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• v.18 no.2
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• pp.101-104
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• 1994

The purpose of the present study was to examine the in vivo activity of oxytocin antagonist I (AI)in the nonpregnant estrous rat. Cannulas were placed in the jugular vein for infusing compounds and a water-filled balloon-tipped cannula placed in one uterine horn for assessing uterine activity. Uterine contractions were monitored with a Grass Polygraph and contractile activity determined as the integrated area for 10 minutes. Five minutes after infusing 5 ${\mu}\textrm{g}$ of AI, 100mU of oxytocin was given as an in bolus injection and repeated every hour for 5 hours. At five minutes, 1 and 2 hours after injection AI the uterine contractile response to 100 mU of oxytocin was significantly inhibited compared to controls(p<0.05). At 3, 4 and 5 hours no differences in response were detected compared to controls(p>0.05). These results in conjunction with other reports from our laboratory suggest that AI has the potential of being a potent and specific tocolytic for prevention of preterm labor in humans.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.332.1-332.1
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• 2014

정보통신 기술의 발전으로 지능형 자동차와 같은 미래형 고부가 가치 자동차 산업은 지속적인 성장이 기대된다. 그리고, 안전과 직결되는 차간 거리 계측은 다양한 종류의 센서에 의해 측정이 되고 있으며, 운전자 및 탑승자의 생명을 보호하고 있다. 다양한 차간 거리센서 중에서도 전방의 물체 인식 및 넓은 영역, 장거리에 대한 센싱은 레이저를 이용하여 구현할 수 있다. 본 논문은 자동차 뿐만 아니라, 지능형 자율 주행시 전방의 물체 인식 및 거리 계측 센서로 적용이 가능한 반도체 레이저의 설계 및 제작에 관해 소개한다. 반도체 레이저는 물질에 따라 각각 다른 파장대역의 광을 조사하고 있으며 이 레이저 빔은 물체에 맞고 부딪히면 반사되어 되돌아 오는 특성을 가지고 있다. 따라서, 펄스 구동에 의해 단위 펄스당 출사되는 레이저는 전방 물체에 부딪혀 되돌아 오는 시간을 구하게 되면 레이저 광원에서 물체까지의 거리를 구할 수가 있게 된다. 여기서 펄스 레이저의 출력은 물체 감지가 가능한 거리의 정보를 가지고 있으며, 펄스로 구동될 때 반복 주파수 및 펄스 폭은 각각 거리계측 시간과 분해능을 결정하는 주요 요소가 된다. 따라서, 장거리 물체의 계측과 물체 식별 능력을 높이기 위해서는 반도체 레이저의 출력을 높이고 펄스폭을 줄여서 분해능을 향상하는 것이 필요하다. 또한, 물체 인식 또는 계측 시간을 빠르게 하기 위해서는 고속 주파수로 동작하게 되면 가능해 질 것이다. 본 논문은 1,550 nm 대역의 반도체 레이저를 제작하여 펄스 구동으로 출력과 펄스폭을 측정하였다. 또한, 보다 높은 전류에서 칩 단면의 열화를 방지하기 위한 기술을 적용하여 설계 및 제작된 레이저의 특성을 측정하여 향후, 지능형 자동차의 레이저 레이다(LIDAR)와 같은 응용분야에 많이 활용될 수 있을 것으로 기대한다.

• Korean Journal of Food Science and Technology
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• v.27 no.1
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• pp.86-91
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• 1995

In order to expand the utility of alginic acid in the food industry, we have investigated to prepare low viscous alginic acid using a method for degradation of alginic acid with the enzyme system of Vibrio sp. AL-145. The enzyme showed maximum activity at pH 8.0 and $37^{\circ}C$, and was stable in the pH range 7.5 to 8.5 and at temperature up to $30^{\circ}C$, and 0.5M NaCl needed for the enzyme activity. The viscosity of alginic acid decreased with the reaction time courses regardless of alginic acid and enzyme concentration, and 90% of viscosity decreased with 60 min of reaction time, but the changes of reducing sugar not exhibited. The soluble concentration of partially degradated alginic acid(PDA) in water was about 10%(w/v), and adsorption capacity of $Ca^{2+}$ ion increased with increasing the concentration of PDA. The alcohol concentration on precipitation of PDA was higher than Na-alginic acid.

• Polymer(Korea)
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• v.38 no.2
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• pp.220-224
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• 2014

Protein adsorption kinetics was studied with the amount of proteins adsorbed to contact lens hydrogels over time scales. Hydroxyethylmethacrylate (HEMA) and silicone hydrogels were dipped in protein solutions (albumin or IgG) and adsorption amounts were measured over time scales. The amount of protein adsorbed to both hydrogel types increased rapidly in 10 min, and remained consistently in 90 min. Decreasing interfacial energetics was taken slowly up to an hour in spite of rapid diffusion of protein molecules. This is due to the fact that water deprivation from three dimensional interphase initially formed by protein diffusion took over an hour. Interpretation of adsorption kinetics on contact lens hydrogels was discussed with understanding of relationship between surface energy and protein adsorption capacity.