• Title/Summary/Keyword: 숙명

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Anti-Inflammatory Active Polysaccharide from Postbiotics of Cordyceps militaris Mycelium-Liquid Culture (동충하초(Cordyceps militaris) 균사체 액체발효 포스트바이오틱스로부터 항염증 활성다당 분리)

  • Yeon Suk Kim;Hyun Young Shin;Hoon Kim;Eun-Jin Jeong;Hyun-Gyeong Kim;Min Geun Suh;Hyung Joo Suh;Kwang-Won Yu
    • The Korean Journal of Food And Nutrition
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    • v.36 no.1
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    • pp.6-16
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    • 2023
  • To investigate the anti-inflammatory activity of submerged culture using Cordyceps militaris mycelium, culture-including mycelia was extracted and lyophilized into postbiotics (hot-water extract; CM-HW). HW was fractionated into crude polysaccharide (CM-CP) by ethanol precipitation, and CM-CP was further dialyzed into CM-DCP by dialysis with running water using 12~14 kDa dialysis tube. When the cytotoxicity of subfractions against cells was assessed, no subfraction had a cytotoxic impact that was substantially different from the control groups. In an inflammatory model using LPS-stimulated RAW 264.7 cells, CM-DCP significantly decreased IL-6 and MCP-1 production levels compared to the LPS-control group. CM-DCP also inhibited IL-6 and IL-8 secretion in HaCaT keratinocytes stimulated with TNF-α and IFN-γ. In the meanwhile, the neutral sugar content and mannose ratio of anti-inflammatory CM-DCP were higher than the other fractions, and CM-DCP contained β-1,3/1,6-glucan of 216.1 mg/g. High pressure size exclusion chromatography revealed that CM-DCP contained molecules with a molecular weight range of 5.6 to 144.0 kDa. In conclusion, postbiotics of C. militaris mycelium significantly promoted anti-inflammatory activity, suggesting that neutral polysaccharides including Glc and Man contribute to the anti-inflammation in RAW 264.7 or HaCaT cells.

A qualitative case study on the experiences of open adoption by adoptive families (입양가족의 개방입양 경험에 대한 질적 사례연구)

  • Kwon, Ji-Sung;Byun, Mi-Hee;Ahn, Jae-Jin;Choi, Woon-Sun
    • Korean Journal of Social Welfare Studies
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    • v.41 no.2
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    • pp.5-33
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    • 2010
  • The purpose of this study is to understand the open adoption experience of adoptive families. For this purpose, the data were collected through diverse data collection methods including in-depth interviews with adoptive families who had experiences of open adoption and analyzed using a qualitative case study approach. Data collected from six adoptive families were employed for within-case analysis and cross-case analysis. Each case was carefully examined and summarized using story-telling style in the within-case analysis and major issues for open adoption appeared in each case were described and compared one by one. In the cross-case analysis, all the cases were re-examined keeping the issues appeared in the within-case analysis in mind and eight integrated themes were emerged from it. The eight integrated themes are 'the crucial meeting', 'a clear arrangement', 'an uneasy parallel', 'the other mom', 'who are the real parents?', 'the words never to say', 'the hidden characters', and 'the center of relations or the outsider'. Based on the results of the study, the policies and practical guidelines related to open adoption were suggested. Also, the suggestions for the further studies were made to obtain more abundant information beyond the limitations of the study.

A Grounded Theory Approach on the Experience of Foster Care Child's Biological Parents (가정위탁아동 친부모의 경험에 대한 근거이론접근)

  • Kim, Jin-Sook;Lee, Keun-Moo
    • Korean Journal of Social Welfare Studies
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    • v.42 no.3
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    • pp.85-119
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    • 2011
  • This Study was to explore the experience of foster care child's biological parents and proposed the practical discuss and method for support their returning home. We approached grounded theory to subject. Twenty biological parent's of foster child participated this research. The Data were collected by in depth-interview and documents. The authors analyzed the data according to frame that proposed Strauss and Corbin(1998). The results as follows: In open coding 143 concepts, 34 subcategory, 13 category. In axial coding the causal conditions were 「self-devaluation」, 「self-stigma」, 「social prejudice」. and the phenomenon were 「life as surplus being」, 「revolving around the world」, and the contextual conditions were 「collapse of life base」, 「rustical fatalism」. The intervention conditions were 「operation of support system」, 「instinct of maternity」. The action/interception strategy were 「closing of single eye」, 「pussling of scattered piece」. The consequence were 「fixations of abandonment」. 「resoaring to the world」 The authors proposed the core category as 「go over the wall of world burdening liabilities of being」. The authors classified patricians life type as 「challenging type」, 「status quo type」, 「escaping type」, Finally, we proposed the practical method for support restoring family the world」, foster care child's biological parents.

A Comparative Study Concerning the Idea of 'Conscience' in Daesoon Thought and Heidegger: Focusing on the Tendency of 'Conscience' to Return to Itself (대순사상과 하이데거의 '양심' 개념에 대한 비교연구 - 근원을 향한 '양심'의 회귀적 특성에 대한 논의를 중심으로 -)

  • Kim, Dae-hyeon
    • Journal of the Daesoon Academy of Sciences
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    • v.28
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    • pp.243-265
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    • 2017
  • In this research, I define 'conscience' in Daesoon thought as the 'Restorative capability of returning to one's roots.' The notion of conscience forms a structure of separation and return, and it is connected to the ascetic aim of realizing human perfection. The conscience opens up potential possibilities and leads realization of potential possibilities by returning to the the point of origin. In the middle of separation and return, the conscience acts as the power of subjectivity possessed by human beings which is known as 'In jon (Human Nobility)' in Daesoon thought. The concept of conscience in Daesoon thought is connected with the subjectivity of In jon and free will as well as the character of subjectivity. This shares commonalities with critical thinking, modern characteristics, and the subjectivity of Heidegger's existentialism. Heidegger describes human fate from an existentialist vantage point using terms such as dasein, Geworfenheit, and Entwurf, and establishes human existence as an act of self-recovery from within in a lonely existential establishment. Daesoon thought implies that humanity is the root of ultimate reality, and this description is in sharp contrast with the thrownness (Geworfenheit) of Heidegger's subjectivity. Therefore, Daesoon thought can be seen as unique in its characterization of humanity as being connected to the root of ultimate reality, autonomy, and independent existence.

The Present Clinical Studies of Oriental Medicine and CAM Therapies in Chemotherapy-induced Peripheral Neurotoxicity (항암제 유발 신경독성을 관리하는 한의학 및 보완대체요법들과 임상시험 현황)

  • Park, Sun-Ju;Go, Ho-Yeon;Han, Yoo-Jin;Ko, Seong-Gyu;Kim, Sung-Hoon
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.205-213
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    • 2009
  • Objectives : Cancer incidence is increasing in all countries and chemotherapy-induced peripheral neuropathy (CIPN) in patients undergoing chemotherapeutic agents have been a clinically serious problems. So far therapeutic options for CIPN patients are limited and no confirmed methods have yet been established for dealing with peripheral neuropathy. Therefore this review is to provide an evidence-based summary of oriental medicine and CAM (complementary and alternative medicine) neuroprotective and treatment therapies which have gone through clinical trials. Methods : An overview of the domestic and international papers of adult clinical trials relating management of only CIPN symptoms through 1990 to present were searched by electronic databases. Search key words were chemotherapy-induced neurotoxicity, chemotherapy-induced peripheral neuropathy, chemotherapy toxicity & herb, chemotherapy toxicity & acupuncture, chemotherapy toxicity & CAM. Only English and Korean written papers were reviewed. Total 25 papers were reviewed in this study, 18 papers were retrieved by electronic search. Results : Clinical studies of managing CIPN were rare, two acupuncture clinical studies and four herb medicinal studies were found. Rest of 19 papers were about other CAM clinical studies. Total 25 papers were analyzed, and all interventions were focused on their pain control efficacy. Other 24 trials of potential therapies except one proved to be effective for CIPN, however some described to be inadequate positive or sufficient negative. Conclusions : As most of the studies were pilot studies, interventions for the prevention and treatment of CIPN have to go through prospective confirmatory studies, such as larger scale randomized, double-blinded, placebo controlled clinical trials must be done for the safe and effective use of proposed therapies. Also standard measurement scales have to be developed for the better clinical study of CIPN.

The effect of transformational leadership recognized by members of the telemarketing organization on organizational performance-centered on the moderating effect of followership (텔레마케팅 조직구성원이 인식한 변혁적 리더십이 조직성과에 미치는 영향-팔로워십의 조절효과를 중심으로)

  • JiHyun Shim
    • Journal of Service Research and Studies
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    • v.12 no.3
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    • pp.45-59
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    • 2022
  • This study attempted to investigate how the transformational leadership perceived by flowers of telemarketing organizations. In particular, this study explored the moderating effect of followership in the relationship between transformational leadership and organizational performance. To verify the research model, 321 surveys collected from 10 domestic call centers were analyzed. Reliability, correlation, factor analysis, and hierarchical regression analysis were performed, and as a result of the analysis, it was found that the transformational leadership in the telemarketing organizations had a positive effect on organizational performance. In addition, it was confirmed that goal consistency, proactive participation, critical thinking, and team spirit, which are the four sub-variables of followership, all have a positive (+) effect on organizational performance, and both goal consistency and proactive participation moderate the relationship between transformational leadership and organizational performance. Considering the special working environment of telemarketing organizations, the results of this study suggest the need for a corporate educational role to increase transformational leadership and followership and the need to build environments by setting up an atmosphere for members to exercise follow-up, and opening up communication structures for members to follow.

The Impact of Nursing Caregivers' Job Enthusiasm on Job Satisfaction: Mediating Effect of Self-Esteem (요양보호사의 직무열의가 직무만족에 미치는 영향: 자아존중감의 매개효과)

  • Jung-Hui, Kim;Mi-Suk, Im
    • Journal of Industrial Convergence
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    • v.21 no.4
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    • pp.157-164
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    • 2023
  • The purpose of this study was to examine the mediating effect of self-esteem in the effect of nursing caregivers' job enthusiasm on job satisfaction. For research analysis, 160 nursing caregivers' engaged in 2 institutions located in Gyeonggi-do, 3 institutions located in Seoul, 5 institutions located in Chungcheongnam-do, and 9 institutions located in Chungcheongbuk-do were surveyed from April 1 to September 2022. Data were collected non-face-to-face using Google links until the 30th. From the collected data of 140 people, 118 copies were used for the final analysis, excluding 22 incomplete responses. First, the effect of positive(+) effect on self-esteem of nursing care workers was confirmed. Second, it was confirmed that caregivers' job enthusiasm had a positive(+) effect on job satisfaction. Third, in the effect of caregiver's job enthusiasm on job satisfaction, it was confirmed as a partial mediating effect of self-esteem. In addition, the Sobel Test was conducted to confirm the significance of the mediating effect, and the significance of the mediating effect was also confirmed. This study has significance in that it suggests social welfare practices and policy interventions necessary to increase job enthusiasm and self-esteem for job satisfaction of nursing care workers, who are the main agents of caring for the elderly.

Analysis of Consumer Characteristics affecting the Availability of Overseas Direct Purchase (해외직구 이용 여부에 영향을 미치는 소비자 특성 분석)

  • Min-Jeong Kim
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.23 no.3
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    • pp.159-166
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    • 2023
  • This study analyzed what consumer characteristics affect the experience of using overseas direct purchase at a time when the overseas direct purchase market is rapidly increasing and consumers' interest in overseas direct purchase is increasing accordingly. For the study, personal data from the 2022 Korea Media Panel Survey were used, and data from 6,734 people who responded "yes" or "no" to whether or not to use overseas direct purchase among 9,941 total respondents were used for analysis. In addition, three variables (demographic, media utilization status, values and lifestyle) were selected among the items of the Korea Media Panel Survey. First, general characteristics were analyzed fo 6,734 people, then, Chi-square test and t-test were performed for comparative analysis between each variable according to the use of overseas direct purchase. Finally, logistic regression analysis was performed to identify the factors affecting overseas direct purchase. As a result of the analysis, 4 out of 5 demographic variables, 2 out of 3 media utilization variables, and 3 out of 7 values and lifestyle variables were derived as decisive factors for using overseas direct purchase. These results can be used to establish marketing strategies that can increase the use of consumers through domestic shopping malls, such as providing differentiated services for the sale of overseas direct shopping products on domestic shopping sites.

A study on Discount in Prior Experience of AI and Acceptance: Focusing on AI Effect (인공지능 사전경험 무시 현상과 수용에 관한 연구: AI Effect를 중심으로)

  • Lee, JeongSeon
    • Journal of Digital Convergence
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    • v.20 no.3
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    • pp.241-249
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    • 2022
  • Artificial intelligence is applied not only to the daily life of individuals but also to all industries, and it is no wonder that the age of artificial intelligence has arrived. Therefore it is important to understand the factors that influence the acceptance of AI. This study analyzes whether "AI Effect" which recognizes that commercialized or familiar artificial intelligence is no longer artificial intelligence, affects the acceptance of artificial intelligence and proposes an acceptance plan based on the results. Two experiments were conducted. The first experiment was conducted on 105 adults in the result it was found that 32.4% (34 people) had AI Effect, AI Effect existed in 43.6% (24 people) of women and 20% (10 people) of men, that is, the proportion of AI Effect exsitence in women is about twice as high.and AI Effect exists when the level of AI knowledge is low. The second experiment was conducted 240 adults and 85 participants with AI Effect were selected. We found the group that recognized experience of AI accepted AI more actively. Understanding of AI Effect is expected to suggest companies' views in order to enhance AI capabilities and acceptance. In addition, future studies are expected on considering individual differences or related to acceptance attitudes.

The Role of Content Services Within a Firm's Internet Service Portfolio: Case Studies of Naver Webtoon and Google YouTube (기업의 인터넷 서비스 포트폴리오 내 콘텐츠 서비스의 역할: 네이버 웹툰과 구글 유튜브의 사례 연구)

  • Choi, Jiwon;Cho, Wooje;Jung, Yoonhyuk;Kwon, YoungOk
    • Journal of Intelligence and Information Systems
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    • v.28 no.1
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    • pp.1-28
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    • 2022
  • In recent years, many Internet giants have begun providing their own content services, which attract online users by offering personalized services based on artificial intelligence technologies. This study investigates the role of two firms' content services within the firms' online service network. We examine the role of Naver Webtoon, which can be characterized as a professional-generated content, within Naver's service portfolio, and that of Google YouTube, which can be characterized as a user-generated content, within Google's service portfolio. Using survey data on viewers' use of the two services, we analyze a valued directed service network, where a node denotes an online service and a relationship between two nodes denotes a sequential use of two services. We found that both Webtoon and YouTube show higher out-degree centrality than in-degree centrality, which implies these content services are more likely to be starting services rather than arriving services within the firms' interactive network. The gap between the out-degree and in-degree centrality of YouTube is much smaller than that of Webtoon. The high centrality of YouTube, a user-generated content service, within the Google service network shows that YouTube's initial role of providing specific-content videos (e.g., entertainment) has expanded into a general search service for users.