• Title/Summary/Keyword: 수혈

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역사 속으로 - ABO식 혈액형분류법을 발견한 카를 란트슈타이너

  • Choe, Yong-Gyun
    • 건강소식
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    • v.34 no.6
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    • pp.38-39
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    • 2010
  • 20세기 초반까지 수혈을 받는 수술 환자가 아무리 수술이 잘 되어도 죽는 경우가 다반사였다. 이때까지만 해도 혈액형이라는 개념이 없어 혈액형에 무관하게 수혈이 이뤄졌기 때문이다. 한 마디로 재수 좋으면 같은 혈액형을 수혈 받고, 재수 없으면 다른 혈액형을 수혈 받는 로또식 수혈이었던 것이다. 로또식의 수혈에서 벗어나 수술의 성공확률을 획기적으로 높인 사람이 있었으니 그가 바로 ABO식 혈액형분류법을 개발한 카를 란트슈타이너(Karl Landsteiner)이다. ABO식 혈액형분류법의 발견은 오늘날까지 이어지고 있는 수혈요법의 틀을 구축했다는데 큰 의의가 있으며, 란트슈타이너는 이 혈액형분류법의 개발로 1930년 노벨의학상을 수상했다.

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Bleeding Tendency and Transfusion Feature after CABG (관상동맥 우회술후 출혈경향과 수혈양상)

  • 이재원;김상필;송명근
    • Journal of Chest Surgery
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    • v.31 no.6
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    • pp.581-585
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    • 1998
  • Postoperative autotransfusion is known as an effective method for blood conservation. We tried to examine whether the autotransfusion of shed mediastinal blood in patients with unstable angina would be valuable for reducing postoperative homologous transfusion by observing the hourly tendency of bleeding and transfusion. Between August and October, 1997, 26 patients with unstable angina underwent coronary arterial bypass surgery by a single surgeon at Asan Medical Center. In retrospective analysis, we found 90% of the patients received homologous transfusions and 85% of them were in the intensive care unit at the same day after operation. In many patients, the cause of transfusion was not anemia but volume replacement. Mean bleeding through the chest tubes was 340 cc for the first 5 hours and 69%(18 pts) showed more than 200 cc of bleeding, the amount generally considered as a initiating point for autotransfusion. Despite the adoption of multiple methods for blood conservation, 90% of the patients needed homologous transfusion. Moreover, many of them had received unnecessary transfusions. We conclude that some kind of blood for transfusion is needed during the immediate postoperative period, and the adoption of postoperative autotransfusion may help in reducing homologous transfusion.

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Open Heart Surgery without Autologous Transfusion (동종수혈없이 시행한 개심술에 대한 연구)

  • Kim, Doo-Sang;Kim, Kyung-Hwan;Ahn, Hyuk;Kim, Yong-Jin
    • Journal of Chest Surgery
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    • v.33 no.12
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    • pp.948-953
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    • 2000
  • 일반적으로 개심술에는 많은 양의 실현이 따르게 마련이고 그 결과로 많은 수혈을 하게 되는데, 응혈 이상증, 과민반응, 급성호흡곤란증 등의 수혈부작용과 간염 및 후천성면역결핍증 등의 질병 감염의 위험성, 그리고 종교적인 이유 등으로 최근들어 동종수혈을 줄이고자 하는 노력이 계속되고 있다. 개심술시 동종수혈에 따른 부작용을 피하기 위해, 동종수혈 없이 자가수혈만으로도 성인개심술이 가능한지 연구하였다. 서울대학교 의과대학 흉부외과학 교실에서는 1996년 1월부터 12월까지 1년 간 자가수혈만으로 개심술을 시행한 실험군 126명과 동종수혈을 시행한 대조군 45명을 대상으로 양군을 비교하였다. 양군 간에 환자의 성별, 대동맥 질환을 제외한 기타 질환, 대동맥수술과정을 제외한 단순 및 복잡수술과정, 평균 대동맥 겸자시간, 수술전 및 수술후 1일째와 7일째 혈색소수치 및 적혈구용적, 수술 전후의 protein 수치와 수술후 albumin 수치, 자가수혈량과 혈장증량제 사용량 등에서는 유의한 차이가 없었으나, 연령, 대동맥질환 및 대동맥수술과정, 평균체외순환시간, 수술 후 회수된 피의 양, 수술직후의 혈색소수치와 적혈구용적, 수술 전 albumin 수치, 그리고 3일간 흉관으로 배액된 양에 있어 차이가 있었다. 본 연구를 통해 동종수혈 없이 자가수혈만으로도 큰 차이없이 여러 종류의 성인 개심술을 성공적으로 할 수 있음을 보고한다.

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Improving the Performance of Blood Transfusion Management Division (수혈관리실의 역할 수행에 따른 개선 효과)

  • Ho-Keun CHOI;Kyung-Suk CHOI
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.1
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    • pp.65-70
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    • 2023
  • The effect of improvement by keeping the former as the priority was examined through an evaluation of the role of the blood transfusion management (BTM) division. This division manages the status of blood for transfusion, evaluates the adequacy of blood transfusion (EABT), monitors and responds to the occurrence of transfusion-related side effects, and performs other tasks necessary for BTM. Although the establishment and operation of the BTM division can lead to the efficient evaluation of transfusion adequacy, there are disadvantages in that it takes time for EABT and it is difficult for the staff in charge of the BTM division to evaluate the adequacy of all the blood. In the future, it is essential to introduce a BTM division and committee specific to Korean patients to implement safe and appropriate BTM in medical institutions, and to assist medical institutions in training their personnel.

The Change of White Blood Cell Count Following Transfusion in Preterm Neonates (미숙아에서 수혈 후 백혈구수의 변화)

  • Yoon, Soo Young;Lee, Gum Joo;Jung, Gui Young
    • Clinical and Experimental Pediatrics
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    • v.45 no.3
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    • pp.325-330
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    • 2002
  • Purpose : We intended to find out how the red cell transfusion would change the white cell count in preterm neonates under treatment in the intensive care unit. We also speculated whether the magnitude of such a change could indicate a potential neonatal infection. Methods : Total white blood cell count, total neutrophil count, and band count were compared and analyzed retrospectively on 33 preterm neonates who received red cell transfusions in our hospital's intensive care unit over a period of two years and a month. Results : We found a mean change of $1.33{\times}10^3/mm^3$ and $0.55{\times}10^3/mm^3$ in total white blood cell count and total neutrophil count in the first eight hours following the red cell transfusion. No significant change was observed in band count between pre and post-red cell transfusion. Conclusion : A mild increase in the white blood cell count caused by an increase in neutrophil count was observed temporarily following the red cell transfusion. But the white blood cell count returned to the pre-transfusion level in about 24 hours, indicating that such a low level of increase cannot be interpreted as an infection of a preterm neonate.

수혈로 인한 에이즈감염, 위험성 있다

  • 이주실
    • RED RIBBON
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    • s.53
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    • pp.16-17
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    • 2003
  • 얼마전 수혈로 인한 에이즈감염보도 이후 헌혈 혈액에 대한 의심이 커지고 있다. 현재 국내에서는 헌혈 혈액에 대해 어떠한 검사를 실시하고 있으며 왜 에이즈에 감염된 혈액이 수혈자에게 공급하게 되었는지 살펴보자.

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Design and Implementation of Mobile Healthcare System supporting Safe Transfusion (안전한 수혈을 지원하는 모바일 헬스케어시스템의 설계 및 구현)

  • Kang, Moon-Seol
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.8
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    • pp.1845-1852
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    • 2015
  • From bar code systems and radio frequency identification (RFID) to beacons utilizing low power bluetooth technology, the fusion of information technology and health and medical treatment is spreading through advances such as automated treatment and examination stages and the use of treatment information connected to smart devices. In this paper, designed and implemented a mobile health care system for the safe management of blood transfusions to prevent accidental problems that can occur during patient blood transfusions. It makes safe and effective blood transfusion possible by using smart devices to read information saved on patient bracelets, blood-collecting containers, blood transfusion bags, and medical personnel identification cards so that they match patient information. By applying the blood transfusion management mobile health care system presented and implemented in this paper to blood transfusion processes in hospitals, it was verified that it allows for safe and effective blood transfusion, preventing accidents which may occur in blood transfusion processes.

Analysis of Massive Transfusion Blood Product Use in a Tertiary Care Hospital (일개 3차 의료기관의 대량수혈 혈액 사용 분석)

  • Lim, Young Ae;Jung, Kyoungwon;Lee, John Cook-Jong
    • The Korean Journal of Blood Transfusion
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    • v.29 no.3
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    • pp.253-261
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    • 2018
  • Background: A massive blood transfusion (MT) requires significant efforts by the Blood Bank. This study examined blood product use in MT and emergency O Rh Positive red cells (O RBCs) available directly for emergency patients from the Trauma Center in Ajou University Hospital. Methods: MT was defined as a transfusion of 10 or more RBCs within 24 hours. The extracted data for the total RBCs, fresh frozen plasma (FFP), platelets (PLTs, single donor platelets (SDP) and random platelet concentrates (PC)) issued from Blood Bank between March 2016 and November 2017 from Hospital Information System were reviewed. SDP was considered equivalent to 6 units of PC. Results: A total of 345 MTs, and 6233/53268 (11.7%) RBCs, 4717/19376 (24.3%) FFP, and 4473/94166 (4.8%) PLTs were used in MT (P<0.001). For the RBC products in MT and non-MT transfusions, 28.0% and 34.1% were group A; 27.1% and 26.0% were group B; 37.3% and 29.7% were group O, and 7.5% and 10.2% were group AB (P<0.001). The ratios of RBC:FFP:PLT use were 1:0.76:0.72 in MT and 1:0.31:1.91 in non-MT (P<0.001). A total of 461 O RBCs were used in 36.2% (125/345) of MT cases and the number of O RBCs transfused per patient ranged from 1 to 18. Conclusion: RBCs with the O blood group are most used for MT. Ongoing education of clinicians to minimize the overuse of emergency O RBCs in MT is required. A procedure to have thawed plasma readily available in MT appears to be of importance because FFP was used frequently in MT.

Analysis of Surgical Blood Use in Operation at YUMC (영남대학부속병원에서의 수술중 수혈량의 분석(1987~1988) - 수술전 혈액의뢰지침 -)

  • Kim, Chung-Sook;Kim, Kyuyng-Dong;Kim, Dae-Chul
    • Journal of Yeungnam Medical Science
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    • v.7 no.1
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    • pp.133-144
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    • 1990
  • This study was performed to guide the effective utilization of blood and optimal blood ordering schedule for various elective surgeries, based on the analysis of 1.462 transfused surgical procedures and 5.933 blood units transfused during operation in the period of two years through January, 1987 to December, 1988 at Yeungnam University Hospital. The frequency of transfusion, and mean transfused units were evaluated and recommended blood unit for each surgical procedure was proposed. We assure that the successful establishment of this guideline can lead to substantial monetary saving, reduced blood outdation, and a decreased blood bank workload with a more appropriate allocation of the technician's time and effort.

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