• Sleep Medicine and Psychophysiology
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• v.1 no.2
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• pp.117-124
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• 1994

Obstructive Sleep Apnea Syndrome(OSAS), that is a complex disease of neuromuscular, respiratory and cardiovascular system, can be cured by various treatment such as weight control, medical and surgical intervention. As most of OSAS may be caused by various anatomical abnormalities, preoperative evaluation for exact anatomical site of obstruction must be needed. And various diagnostic procedures such as fiberoptic nasopharyngoscopy, Mueller test, cinefluoroscopy, cephalometry, computerized tomography, polysomnography would be used for this purpose. Uvulopalotopharyngplasty is currently the most popular method for the patient with OSAS among various surgical maneuvers and is very effective for the relieving the symptoms as like snoring, daytime somnolence, and nocturnal restlessness etc. Although subjective improvement is not compatible with it's objective assessment in postoperative evaluation for it's results, uvulopalatopharyngoplasty could be a recommandable surgical procedure because of it's ample effectiveness in promoting symptom improvement without any risk of serious complications.

• 건강소식
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• v.34 no.8
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• pp.18-23
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• 2010

안녕히 주무셨습니까? 이른 아침 어른을 문안할 때 흔히 사용하는 인사말이다. 그만큼 인간의 생활에서 잠이 중요한 역할을 차지하고 전날 밤에 잘 잤는지의 여부가 다음날 기분을 좌우하기 때문이다. 잠이 보약이라는 말이 있다. 반대로 생각하면 잠을 제대로 자지 못하면 건강에 적신호가 켜진다는 것이다. 잠을 제대로 못 이루게 만들거나 잠을 자도 피곤하게 만드는 원인은 매우 다양하다. 우울증, 수면무호흡증, 하지불안증, 기면증 등이 대표적인 원인들이다. 편안한 숙면을 방해하는 원인들을 사례를 통해 알아본다.

• The Journal of the Korean life insurance medical association
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• v.31 no.1
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• pp.29-33
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• 2012

Nowadays, obstructive sleep apnea is being important to life insurance industry. Many life applicants submit their attending physician's statement, diagnostic certificate, and results of polysomnography to underwriters. So It's necessary to perform evidence-based medical approach. I hope this article is helpful to insurance doctors and underwriters.

• The Monthly Diabetes
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• s.148
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• pp.16-17
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• 2002

비만과 관련된 질환은 당뇨병, 고혈압, 고지혈증, 죽상경화증(동맥경화증), 심근경색증, 지방간, 담석증, 골 관절염, 통풍, 폐쇄성 수면 무호흡증, 대장암, 직장암, 전립선암, 유방암, 자궁내막암 등의 각종 암, 불안, 우울, 적응장애, 히스테리 등의 심리적 질환 등이 있다. 비만이 있을 때 우리 몸에서는 인슐린 자체에 대한 저항성이 생겨서 말초조직에서의 포도당 이용이 감소된다. 연구에 의하면 표준체중의 45$\%$ 이상을 초과한 비만환자는 당뇨병 발생의 위험도가 30배 증가된다고 알려져 있다. 비만이 있을 때 흔히 동반되는 질환들 중 특히 고혈압, 고지혈증, 죽상경화증 등의 질환은 당뇨가 있을 때 흔히 동반될 수 있는 질환들이고, 인슐린 저항성과 깊은 관계가 있는 질환들로 당뇨인들에게 비만은 매우 중요한 질환이라고 할 수 있겠다.

• The Journal of the Korean dental association
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• v.53 no.4
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• pp.259-265
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• 2015

Recently, oral appliances for treating snoring and obstructive sleep apnea are widely used. Among various appliances, mandibular advancement devices are most effective without serious side effects. Advancement of mandible keep airway open and decrease snoring and/or obstructive apnea events. They can be used as stand-alone therapy or an adjunct to continuous positive air pressure for lowering air pressure. Oral appliances should be applied by dentists who have knowledges and experiences on occlusion and temporomandibular disorders and manage of side effects.

• Sleep Medicine and Psychophysiology
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• v.1 no.1
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• pp.60-67
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• 1994

Objectives: The Obstructive sleep apnea syndrome is characterized by snoring, observed apnea during sleep and excessive daytime sleepiness. The overnight polysomnographic recording is used to investigate patients with possible obstructive sleep apnea syndrome. But the overnight polysomnographic recording is time consuming, expensive, and labor-intensive. Recently in diagnosis of obstructive sleep apnea syndrome, several simple screening tests have been suggested. Methods: This study was performed to assess the probability of application of clinical features and the degree of oxygen desaturation as a screening test for the obstructive sleep apnea syndrome. The sensitivity and specificity of the self-report of clinical features including snoring, observed apnea during sleep, excessive daytime sleepiness and insomnia were tested. And the degree of oxygen desaturation measured by oximetry in 42 subjects were compared with the overnight polysomnographic recording results. Results: In the prediction of apnea index more than 5, the sensitivity of observed apnea during sleep, snoring, excessive daytime sleepiness and insomnia were 96.8%, 93.5%, 38.7%, 25.8% and the specificity of those clinical features were 182%, 36.4%, 100%, 72.7%, respectively. In the prediction of apnea index more than 5, the sensitivity and specificity of the combination of more than three self-report clinical features were 54.8% and 90.9%. The degree of oxygen de saturation and maximal apnea duration in the group of apnea index more than 5 were significantly different from those in the group of apnea index below 5(P<0.001). And the apnea index was significantly correlated with the degree of oxygen desaturation and maximal apnea duration(P<0.001). Conclusion: These results suggest that application of clinical features alone as a screening test for the obstructive sleep apnea syndrome is inadequate because of it's high rate of false positive and false negative results. The degree of oxygen desaturation measured by oximetry is possibly applicable to screening test and follow up evaluation of treatment efficacy for the obstructive sleep apnea syndrome.

• Korean Journal of Biological Psychiatry
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• v.16 no.2
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• pp.69-75
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• 2009

Objectives : The detrended fluctuation analysis is one of the nonlinear methods for the investigation of biological time series. It quantifies the fractal scaling properties and is known to be useful in the evaluation of long-range correlations in time series. The heart rate variability(HRV) of obstructive sleep apnea syndrome (OSAS) patients during nighttime was analyzed by detrended fluctuation analysis to assess its relationship with the severity of the symptoms. Methods : Fifty nine untreated male OSAS patients with moderate to severe symptoms(mean age=45.4${\pm}$11.7 years, apnea-hypopnea index, AHI${\geq}$15) underwent nocturnal polysomnography. Moderate(AHI=15-30, N=22) and severe(AHI>30, N=37) OSAS patients were compared for the indices derived from detrended fluctuation analysis and frequency domain analysis of HRV. Results : In the detrended fluctuation analysis, the alpha values were 0.75${\pm}$0.11 and 0.82${\pm}$0.07 for the severe and the moderate OSAS groups respectively. The difference was significant(p<.01). The alpha value had negative correlation with AHI(r=-.425, p=.001). Negative correlation coefficients were also found in the relationships between the alpha values and very low frequency(VLF)(r=-.425, p=.001), low frequency(LF)(r=-.633, p= <.001) and the LF/HF ratio(r=-.305, p=.019) respectively. LF/HF ratio(p=.005) was higher in the severe OSAS group compared to that of the moderate OSAS group. Conclusion : In this study, the detrended fluctuation analysis showed the significant difference between the two OSAS groups classified according to their severity of symptoms. The scaling exponent showed the negative correlation with AHI and indicies of frequency domain analysis. This result suggests that detrended fluctuation analysis can be helpful to estimate the severity of OSAS.

• The Journal of the Acoustical Society of Korea
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• v.40 no.2
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• pp.155-160
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• 2021

This paper proposes an automatic method for detecting snore sound, one of the important symptoms of sleep apnea patients. In the proposed method, sound signals generated during sleep are input to detect a sound generation section, and a spectrogram transformed from the detected sound section is applied to a classifier based on a Convolutional Bidirectional Gated Recurrent Unit (CBGRU) with attention mechanism. The applied attention mechanism improved the snoring sound detection performance by extending the CBGRU model to learn discriminative feature representation for the snoring detection. The experimental results show that the proposed snoring detection method improves the accuracy by approximately 3.1 % ~ 5.5 % than existing method.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.2
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• pp.157-161
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• 2001

The purpose of this study cephalometrically evaluated changes in the posterior airway space for patients with obstructive sleep apnea syndrome(OSAS) before and after surgical advancement of the maxilla and mandible. The change in calculated airway resistance was correlated with the respiratory disturbance index(RDI). Twenty cephalometric radiographs were traced before and after surgery to determine the posterior airway area and calculate resistance. Polysomnograms of each patient were obtained before and after surgery. All patients had a decrease in calculated airflow resistance in the airway. The mean amount of resistance was 865.15 before surgery, decreasing to 192.65 after surgery (p<0.01). Eighty-five percent of the patients experienced improvement in their RDI. Reduction in the RDI appears to be due to an increase in the posterior airway space and decrease in flow resistance.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1993.05a
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• pp.100-100
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• 1993

Palatopharyngoplasty has been widely performed for the treatment of chronic snoring and obstructive sleep apnea syndrome. Lack of literature for long term effectiveness and complications of palatopharyngoplasty made us to report our result with minimum follow up of 5 years, compare to preop and postop 8 weeks deta. We evaluated subjective symptom and objectively documented polysomnographic improvement of 25 among 37 patients undergoing palatopharyngoplasty from 1987 to 1985. The remaining 12 patients were lost to follow up (1) snoring was abolized in 10 patients(40%) of these 25 patients and with vary degree(Grade 1-3), reduced in remainders except 3 patients (2) Sleep apnea seen preoperatively in 15 patient (AI > 20) was reduced to Grade 0 or Grade 1 in 13 patients. And marked change in AI & body weight was not seen at 5 year after operation. (3) 3 cases of mild velopharyngeal insufficiency, 1 case of asymmetry of soft palate 5 cases of pharyngeal dryness, were observed in this retrospective study and there was no nasopharyngeal stenosis loss of taste respiratory and cardiovascular complications.