• Journal of Yeungnam Medical Science
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• v.24 no.2
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• pp.107-118
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• 2007

Background : It is well known that non-rapid eye movement(NREM) sleep activates the occurrence of interictal epileptiform discharges(IED) in many epileptic syndromes. We performed this study to assess the effect of NREM sleep on IED in epileptic patients with organic brain lesions. Materials and Methods : We analyzed awake and sleep electroencephalopathy(EEG) recorded simultaneously after partial sleep deprivation in 50 patients. We calculated the awake and sleep spike index (ASI and SSI, spikes/epoch), and the percentage increase of ASI and SSI during sleep. Results : In the 50 patients, the IEDs were recorded exclusively during the awake state in 1 (2%) patient, and during the sleep state in 13(26%) patients. The SSI was higher in 44 (88%) patients, and the ASI was higher in 5 (10%) patients. The mean ASI and the SSI in patients with organic brain lesions were $0.058{\pm}0.121$ and $0.148{\pm}0.187$, and it was $0.081{\pm}0.150$ and $0.174{\pm}0.226$ in patients without organic brain lesions. There were significant increases in the spike index (P<0.05) during NREM sleep in both groups (n=36), but no significant difference in the percent increase of spike index (P>0.05). Conclusion : The IEDs were activated significantly during NREM sleep both in patients with and without organic brain lesions, but there were no differences in the degree of activation in both groups. The activating effect of NREM sleep was not correlated with clinical factors such as, frequent nocturnal seizures, frequent generalized tonic clonic seizures, type of epilepsy and taking anticonvulsants. We conclude that the routine EEG used to evaluate epileptiform discharges in epileptic patients should include sleep recordings after partial sleep deprivation.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.44-44
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• 2015

저수지나 하천 사면에서 발생하는 산사태와 토석류는 저수지와 하천 수체에 충격을 가한다. 이로 인해 발생하는 수면 충격파는 전파되어 반대편 제방으로 파의 처오름 또는 댐 제체위로의 물넘이로 큰 피해를 줄 수 있다. 최근 외국에서는 2차원 충격파 생성 및 전파의 기본 과정을 구명하기 위한 실험적 연구가 이뤄지고 있으며, 이들 연구들은 충격파의 발생과 전파, 사면활동 물질과 수체의 상호작용 그리고 자유 수면과 유속분표의 발달에 대한 자세한 관측 자료를 제시하고 있다. 아울러 충격파에 영향을 주는 지배 매개변수를 제시하고 있다. 하지만, 이러한 실험적 연구의 최근 진보에도 불구하고, 이들 지배 매개변수를 고려한 충격파 지배공식들은 대상 지역의 복잡한 바닥 지형이나, 평면적 지형 변화를 단순한 추정치로만 고려하게 된다. 따라서 복잡한 지형조건에서 토석류와 수체의 상호작용과 수면 충격파의 전파를 합리적으로 해석하는 데는 한계가 있다. 이 경우 수치모델링 기법을 대안으로 적용할 수 있으나, 수치모델링은 수면에서 충격파의 전파와 수중에서 토석류의 전파를 동시에 모의해야 하고, 뉴턴 유체와 비뉴턴 유체의 특성을 동시에 고려해야하므로 수치해석 연구자들에게는 하나의 큰 도전사항이다. 이 연구는 경계면 포착기법을 이용한 계산유체동력학 기법을 이용하여 사면활동과 이로 인한 정지 수역에서의 충격파의 발생 및 전파를 재현하기 위한 수치 모델링 기법을 개발하는 것이 목적이다. 사면활동과 수면의 경계면을 포착하고 위치를 정립하기 위해서 VOF (volume of fluid) 경계면 재구축 기법을 이용한다. 지배 방정식은 비압축성(incompressible) 질량 보존방정식과 나비어-스톡스(Navier-Stokes) 방정식이며, 서로 다른 유체의 상(phase)애 대한 체적분할이송방정식을 이용한다. 큰와 모의 계열의 난류 모델링 기법을 적용하여 충격파의 전파와 붕괴에 대한 난류의 영향을 고려하였다. 토석류는 비뉴턴 흐름저항 관계식을 적용하여 그 흐름특성을 재현하였다. 이들 지배방정식은 2차 정확도의 유한체적법(finite volume method)을 이용하여 해석한다. 외국의 연구자들이 관측하여 제시한 길이 11 m 그리고 폭 0.5 m의 수로에서 발생한 충격파를 수치적으로 재현하여 개발된 모형의 실제 문제에 대한 적용성을 보여준다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.36 no.5
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• pp.819-830
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• 2016

Hydrodynamic characteristics of wave propagation through density stratification have not been identified in details. So this study conducted a numerical simulation using LES-WASS-3D ver. 2.0 for analysis of density current due to water temperature and salinity in order to analyze hydraulic characteristics under wave action in a two-layer density stratified fluid. For the validity and effectiveness of numerical wave tank used, it was compared and analyzed with the experiment to show waveform based on $3^{rd}$-order Stoke wave theory at the internal of a density stratification. Using the results obtained from numerical simulation, the surface and internal wave heights are reduced as the wave propagates in a two-layer density stratified water. And the surface or internal wave attenuation became more serious as the vorticities were increased by the velocity difference of wave propagation due to the upper-lower density difference around the interface of a density stratification. As well, the surface and internal wave attenuations became more serious with higher density difference and depth ratio between upper and lower layers when the wave propagates through a density stratification.

• Clinical and Experimental Pediatrics
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• v.51 no.8
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• pp.861-867
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• 2008

Purpose : We carried out this study to determine if there is any difference in the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG and if there are any factors influencing on the occurrence rate of EEG. Methods : This study included 178 epileptic children who had visited neurology clinic of the department of pediatrics, Pusan National University Hospital from July 2005 to July 2006. The medical and EEG records of these children who had had both awake EEG and sleep EEG were reviewed. We analysed the occurrence rate of the epileptiform discharge between awake EEG and sleep EEG. We investigated the related clinical factors which included sex, seizure types, underlying causes, age at first seizure, antiepileptic drug (AED) medication, age at recording, and background activity. Results : Among 178 epileptic children, 91 patients (51.1%) showed epileptiform discharge in awake or sleep states, 10 patients (11.0%) abnormal only in awake, 40 patients (44.0%) abnormal only in sleep, 41 patients (45.0%) abnormal in both awake EEG and sleep EEG. The occurrence rate of sleep EEG was 81 of 178 patients (45.5%) which was more than that of the awake EEG (28.7%) (P<0.001). The occurrence rate of sleep EEG is more than that of the awake EEG regardless of sex and underlying causes. But there is no significant difference from awake EEG and sleep EEG in finding the epileptiform discharge in the patient with generalized seizure, younger than 5 years old at first seizure, younger than 10 years old at recording, no antiepileptic medication, and abnormal background activity. Conclusion : The sleep EEG is thought to be more helpful in the diagnosis of childhood epilepsy.

• Journal of Ocean Engineering and Technology
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• v.16 no.3
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• pp.34-39
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• 2002

본 논문에서는 수면파(Surface wave)와 수중파 (Internal wave)간의 동적 상관관계에 관하여 수행된 연구결과를 정리하였다. 표면파의 비선형 문제는 파의 경사매개변수를 2차원으로 가정하여 해석하였으며, Cauchy 문제는 불균일 조류상의 균일 수면중력파에 대하여 해석하였다. 또한, 파의 경사, 주기의 범위(Frequency range) 그리고 자유표면하의 조류의 분포들간의 조화에 대한 연구가 수행되었으며 해류 및 이동파와 연계되어 수중파의 최전 후방에 형성될 수 있는 정적 파형 (Steady wave pattern)이 수면파형에 포함되었다.

• Proceedings of the Optical Society of Korea Conference
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• 2001.02a
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• pp.90-91
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• 2001

파동의 기본적인 성질을 이해하는데 있어서 중요한 실험 중에 하나가 Ripple Tank 실험이다. 그러나, 기존의 실험 장치에서 사용되고 있는 광원은 점광원이 아니어서 수면파의 상을 관찰하기가 쉽지 않다. 본 실험에서는 이것을 보완하기 위해 광원으로 레이저를 사용하였는데 그 결과 선명한 상과 함께 기존의 광원으로는 볼 수 없었던 현상까지도 관찰할 수 있었다. (중략)

• Journal of Life Science
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• v.22 no.8
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• pp.1077-1084
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• 2012

This study investigated the effects of Origanum majorana essential aroma therapy on electrical activity in the brain as evaluated by an electroencephalogram (EEG). The subjects were 29 healthy female young adults, and their sleep quality was assessed by using the Pittsburgh Sleep Quality Index. EEG electrodes were attached at the frontal, temporal, occipital, and parietal lobes according to the international 10-20 system. Subjects were exposed to organic Origanum majorana essential aroma (50 ${\mu}l$) for a period of 3 minutes each before, during, and after aromatherapy. Subjects with good sleep quality showed that Origanum majorana essential aroma increased the theta power at the frontal and temporal lobes of both cerebral hemispheres, the left parietal lobe, and the right occipital lobe. Furthermore, Origanum majorana essential aroma decreased the alpha power at the left occipital lobe and the beta power at the right temporal lobe. On the other hand, subjects with poor sleep quality showed an increase in the theta power at the temporal lobe of both cerebral hemispheres and a decrease in the alpha power at the left parietal lobe by Origanum majorana essential aroma therapy. It is concluded that Origanum majorana essential aroma therapy diminishes the state of wakefulness in the brain; alpha and beta powers were both decreased in the subjects with good sleep quality, but only alpha power was decreased in the subjects with poor sleep quality. Moreover, Origanum majorana essential aroma therapy has a sleep-inducing effect in both subjects with good sleep quality and poor sleep quality.

• Journal of Korea Ship Safrty Technology Authority
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• v.6
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• pp.76-84
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• 2001

수중익선과 같은 고속선의 경우 수중익이 수면근처에 접근하면 여러형태의 파를 유기하게 되며 그에 의한 압력의 변화를 유발시킨다. 이에따라 양력이 감소하고 조파저항이 증가하다가 한계 Froude 수에 이르게 되면 파가 더이상 자신의 형태를 유지하지 못하고 부서지는 쇄파가 발생하면서 조파저항은 감소하고 그대신 쇄파저항이 급격히 증가하게 된다. 이에대한 연구의 한 방법으로 수면하에서 정속으로 움직이는 수중익에 의하여 생성되는 정상파 및 쇄파현상에 대한 연구를 회류수조에서 수행하였다.

• Sleep Medicine and Psychophysiology
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• v.10 no.2
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• pp.100-107
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• 2003

Objectives: Periodic leg movements in sleep (PLMS) might be subdivided based upon whether or not they are associated with visible EEG microarousals (MA). MA is considered to be responsible for nonrestorative sleep and daytime fatigue. The American Sleep Disorders Association's (ASDA) scoring rules for MA based on visual analysis of the EEG changes suggest that MA should last more than 3 seconds. However, it has been suggested that visual analysis may not detect some changes in EEG activity. This study is aimed at measuring changes in EEG spectra during PLMS without MA in order to better understand the arousing response of PLMS. Methods: Ten drug-free patients (three men and seven women) diagnosed with PLMS by polysomnography were studied. Spectral analysis of the EEG was performed in each patient on 30 episodes of PLMS without MA, chosen randomly across the night in stage 2 non-REM sleep. We applied stricter criteria for MA compared to ASDA, by defining it as a return to alpha and theta frequency lasting at least 1 second. Results: The mean PLMS index was $16.7{\pm}10.0$. The mean PLMS duration was $1.3{\pm}0.7$ seconds. Comparison of 4-second EEG activity both before and after the onset of PLMS without MA using independent t-test showed that the movements were associated with significant increase of relative activity in the delta band (p=0.000) and significant decrease of activity in the alpha (p=0.01) and sigma (p=0.000) bands. No significant decrease in the theta (p=0.05), beta (p=0.129), or gamma (p=0.062) bands was found. Conclusion: PLMS without MA was found to be associated with EEG change characterized by increase in the delta frequency band. This finding seems to be compatible with the hypothesis of an integrative hierarchy of arousal responses of Sforza's. Considering that the subjects had lower PLMS index and shorter PLMS duration than those of the previous study, it is suggested that an even less severe form of PLMS without MA could induce neurophysiologic change, which may potentially be of clinical significance.

• Science of Emotion and Sensibility
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• v.15 no.4
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• pp.453-468
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• 2012

This study investigated the effects of Lavandula angustifolia (L. angustifolia) aroma on the brain electrical activity evaluated by an electroencephalogram (EEG) in the male adults since many researches were performed with females and few with males. Sleep quality of 35 male adults were analyzed by Pittsburgh sleep quality index, and they were divided into two groups of good sleep quality and poor sleep quality. EEG electrodes were attached at the frontal (F3, F4), temporal (T3, T4), occipital (O1, O2), and parietal (P3, P4) regions according to the International 10-20 system. EEG was measured for 3 min per each period of before, during, and after L. angustifolia aromatherapy. Subjects with good sleep quality showed increases in the delta power at the parietal region of both cerebral hemispheres and in the theta power at the temporal region of right hemisphere (p<0.05), and a decrease in the alpha at the parietal region of both cerebral hemispheres (p<0.05). And subjects with poor sleep quality showed increases in the delta power at the frontal region of left cerebral hemisphere and in the theta power at the frontal region of both hemispheres (p<0.05). It is concluded that L. angustifolia aroma has effects on decreasing an awakening status related-brain wave and increasing the sleep status related-brain waves in the male adults with good sleep quality, and has also effects on increasing the sleep status related-brain waves in the male adults with poor sleep quality.