• Journal of Acupuncture Research
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• v.26 no.5
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• pp.39-47
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• 2009

목적 : 정상 췌장조직 속에 존재하는 췌장 소도세포들을 파괴시켜 고혈당을 유발시키고 복령 물추출물로 약침을 시술하여 췌장 조직의 보호효과와 항당뇨 효과를 살펴보고자 실험을 진행하였다. 방법 : 5주령의 Sprague-Dawley rat을 통제된 실험실 환경에 적응시킨 후 1주일간 복령약침액(125mg/kg 복령약침군 및 250mg/kg 복령약침군)을 좌우 신수($BL_{23}$)에 교대로 각각 피하에 약침하고 streptozotocin을 복강내 주사하여 3일 후 diabetes mellitus 유도 정도를 평가하고 2주일간 추가 치료를 진행 한 뒤, 혈액지표(plasma glucose, insulin, TG, TC, NEFA, sGOT, sGPT, ALP, BUN, CRE)와 췌장조직의 형태학적 분석 및 염증 관련 단백질의 발현을 평가하였다. 결과 : 복령약침군(125mg/kg 복령약침군 및 250mg/kg 복령약침군)에서 insulin과 triglyceride, NEFA 수치가 유의하게 감소하였으며 간 기능 효소수치인 sGOT가 감소하는 경향을 나타내었으나, 신장기능지수는 유의한 감소를 나타내지 않았다. 특히 250mg/kg 복령약침군에서 streptozotocin 투여로 인한 pancreatic islet의 형태학적 변성이 현저하게 개선되었다. Western blot 결과 JNK-2, P-JNK-2, P-JNK-1, ERK1/2 및 phosphorylated ERK1의 발현이 감소되었다. 결론 : 복령약침이 고인슐린혈증과 고지질질혈증을 개선시키고 streptozotocin에 의한 pancreatic islet의 파괴를 억제하며, 이는 inflammation-related transcription factor인 NF-kB와도 관련이 있는 것으로 판단된다. 향후 복령약침의 항당뇨 효과와 그 기전에 관한 추가 연구가 필요할 것으로 사료된다

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.1D
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• pp.127-132
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• 2011

Load managing method on road became necessary since overloaded vehicles occur damage on road facilities and existing systems for preventing this damage still show many problems. Accordingly, efficient managing system for preventing overloaded vehicles could be organized by using the road itself as a scale by applying genetic algorithm to analyze the load and the drive information of vehicles. First of all, accurate analysis of load using the behavior of road itself is needed for solving illegal axle manipulation problems of overloaded vehicles and for installing intelligent embedded load analyzing system. Accordingly in this study, to use the behavior of road, the transformation was measured by installing underground box type indoor model and indoor experiment was held using genetic algorithm and 10% error were checked.

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.372-383
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• 2011

Our study was carried out to develop the severity-adjustment model for length of stay in hospital for percutaneous coronary interventions so that we would analysis the factors on the variation in length of stay(LOS). The subjects were 1,011 percutaneous coronary interventions inpatients of the Korean National Hospital Discharge In-depth Injury Survey 2004-2006 data. The data were analyzed using t-test and ANOVA and the severity-adjustment model was developed using data mining technique. After yielding the standardized value of the difference between crude and expected length of stay, we analysed the variation of length of stay for percutaneous coronary interventions. There was variation of LOS in regional differences, size of sickbed and insurance type. The variation of length of stay controlling the case mix or severity of illness can be explained the factors of provider. This supply factors in LOS variations should be more studied for individual practice style or patient management practices and healthcare resources or environment. We expect that the severity-adjustment model using administrative databases should be more adapted in other diseases in practical.

• Journal of Korean Society of societal Security
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• v.2 no.4
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• pp.35-41
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• 2009

If any bridge has the monitoring system, the bridge manager can check the history of bridge behavior and the progress of the damage more exactly. When the unexpected event (ex: earthquake and flood) happens, the manager can check the safety condition of the bridge and make the pertinent action for bridge management which is reduction of vehicle speed or traffic control through the system. Additionary the manager can make the well-timed repair or reinforcement through the system, so he can save the management cost or the life cycle cost. This study presents the method of setting the criteria by FEM analysis in bridge monitoring system, and the standard progress for setting the criteria about measurement items of monitoring system for the steel box type bridge.

• Journal of Trauma and Injury
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• v.26 no.1
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• pp.14-17
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• 2013

Purpose: The open abdomen is now the standard of care in various clinical situations, especially it is used to treat abdominal compartment syndrome. Many techniques have been reported for closure after an open abdomen, but most take a long time for complete definitive closure and are associated with various problems. We describe a technique using biologic mesh that can achieve early definitive closure after an open abdomen. Methods: A 45-year-old man presented to the emergency room with a painful hip and painful lower extremities after a fall from 80 feet. Radiologic examination revealed multiple fractures of the pelvis and low extremities. Abdominal compartment syndrome caused by a retroperitoneal hematoma developed during the orthopedic surgery. We performed exploration immediately and closed abdomen temporarily. A peritoneal graft of porcine dermal collagen with anterior myofascial approximation of the rectus abdominis muscles and sliding skin flap was performed three days after the previous surgery. Results: There were no complications related to the wound. The patient was transferred to the Department of Orthopedic Surgery seven days after the initial surgery. Conclusion: Early definitive closure using porcine dermal collagen is a feasible method that can reduce the length of hospitalization and the number of operations for an open abdomen.

• Journal of Internet Computing and Services
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• v.11 no.4
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• pp.129-141
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• 2010

In digital computing environment, for the mal functions in appliances and system errors, the unaccepted intrusion should be occurred. The evidence collecting technology uses the system which was damaged by intruders and that system is used as evidence materials in the court of justice. However the collected evidences are easily modified and damaged in the gathering evidence process, the evidence analysis process and in the court. That’s why we have to prove the evidence’s integrity to be valuably used in the court. In this paper, we propose a mechanism for securing the reliability and the integrity of digital evidence that can properly support the Computer Forensics. The proposed mechanism shares and manages the digital evidence through mutual authenticating the damaged system, evidence collecting system, evidence managing system and the court(TTP: Trusted Third Party) and provides a secure access control model to establish the secure evidence management policy which assures that the collected evidence has the corresponded legal effect.

• Journal of the Society of Naval Architects of Korea
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• v.57 no.4
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• pp.221-229
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• 2020

Naval ships could be seriously damaged by enemy attacks in battle. Moreover, this damage could be spread and deteriorated into a secondary accident. Secondary accidents that have adverse effects on naval ship's survivability, such as fire, flood, smoke extension, and patient occurrence, are defined as casualties. These casualties sharply degrade the survivability of naval ships. Furthermore, naval ships could be burned-out and sunk by casualties in isolated sea. Therefore, damage control and rapid suppression of the casualties in the naval ships is essential. This study was conducted in the establishment of suppression paths according to the characteristics of each casualty so that the developed system can support the rapid suppression in an emergency and even the training situation on a regular state. To establish the suppression paths, the two-dimensional numerical map is designed by converting the three-dimensional features of the naval ships, and the well known algorithms are compared to present the appropriate one for path finding problem on the naval ships. Finally, we devised a specific routing algorithm that fits the characteristics of each casualty in accordance with the Korean Navy's doctrines and handbooks of casualty suppression.

• Journal of the Korea institute for structural maintenance and inspection
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• v.14 no.1
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• pp.117-124
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• 2010

Different to other social infrastructures, bridge elements or bridges can be damaged or collapsed and this may cause death toll and severe social and economical damage, bridges should be managed to maintain a safety level. Diverse strengthening methods is developed to improve a deteriorated bridge performance up to original design level. But rational decision-making process and methodologies to select a optimum strengthening method are absence yet in Korea. This paper therefore derived items and proposed methodologies for quantity estimate considering uncertainty to select a optimum strengthening method among conceptually designed alternatives. And also, to demonstrate the applicability and verification of the proposed approach, it was applied to select the optimum strengthening method for the deteriorated T-shape concrete girder bridge. The model and the procedure can greatly contribute to the uncertainty-oriented alternative selection.

• Korean Journal of Social Welfare Studies
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• v.45 no.2
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• pp.233-261
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• 2014

There are two competing models explaining the causal relationship of depression and self-esteem, and they are cognitive vulnerability model and the scar model. Cognitive vulnerability model explains that low self-esteem poses as a risk factor for development of depressive symptoms/depression while the scar model asserts that the experiences of depression scars the cognitive function of individuals, resulting in negative self-perception. This study was set out to test two models on Korean adults, and to identify factors that are associated with depression and self-esteem relationship. The first four waves (wave 1~4) of the Korea Welfare Panel Study (KOWEPS) were used for analyses, and latent growth curve modeling was employed to examine the relationship. The findings show that the relationship was reciprocal, one affecting the growth trajectory of another over a four year period. Furthermore, education, poverty status, health status, and satisfaction with social relationships were found to be significantly associated with both depression and self-esteem trajectories. Implications for practice and theory are provided.

• International Area Studies Review
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• v.12 no.3
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• pp.89-109
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• 2008

Using hybrid channel affords the benefits of achieving control through the direct channel and achieving flexibility through the indirect channel. However, using a hybrid channel also poses special challenges to a manufacturer, including the problem of managing multiple channel members with disparate goals and priorities. The purpose of this study is to enhance our understanding on the management of hybrid channel. We study marketing channels for fashion apparel to examine governance challenges and solutions of a hybrid channel. We have two objectives to fulfill that purpose. First, we aim to tie two largely separate research streams of salesforce management and marketing channel management together by examining both intrafrim governance and interfirm governance issues under one conceptual framework. Second, we aim to lay a ground work for rigorous further research on this topic by tying two major theoretical approaches of governance together under one conceptual framework. Our predictions were tested with data from the survey of apparel manufacturers and retailers. The analysis results support the predictions moderately.