• Title/Summary/Keyword: 손상 영역

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Study on Peridynamic Interlayer Modeling for Multilayered Structures (가상 절점을 이용한 적층 구조물의 페리다이나믹 층간 결합 모델링 검토)

  • Ahn, Tae Sik;Ha, Youn Doh
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.30 no.5
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    • pp.389-396
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    • 2017
  • Peridynamics has been widely used in the dynamic fracture analysis of brittle materials. Recently, various crack patterns(compact region, floret, Hertz-type crack, etc.) of multilayered glass structures in experiments(Bless et al. 2010) were implemented with a bond-based peridynamic simulation(Bobaru et al.. 2012). The actual glass layers are bound with thin elastic interlayer material while the interlayer is missing from the peridynamic model used in the previous numerical study. In this study, the peridynamic interlayer modeling for the multilayered structures is proposed. It requires enormous computational time and memory to explicitly model very thin interlayer materials. Instead of explicit modeling, fictitious peridynamic particles are introduced for modeling interlayer materials. The computational efficiency and accuracy of the proposed peridynamic interlayer model are verified through numerical tests. Furthermore, preventing penetration scheme based on short-range interaction force is employed for the multilayered structure under compression and verified through parametric tests.

Synthesis and Secretion of Mutant Mannose-Binding Lectin (돌연변이 Mannose-binding Lectin 합성과 세포 병리적 연구)

  • Jang, Ho-Jung;Chung, Kyung Tae
    • Journal of Life Science
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    • v.23 no.3
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    • pp.347-354
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    • 2013
  • Innate immunity is the ability to differentiate infectious agents from self. The innate immune system is comprised of a complicated network of recognition and effector molecules that act together to protect the host in the early stage of an infectious challenge. Mannose-binding lectin (MBL or mannose-binding protein, MBP) belongs to the family of $Ca^{2+}$-dependent lectins (C-type lectin with a collagen-like domain), which are considered an important component of innate immunity. While it is associated with increased risk and severity of infections and autoimmunity, the most frequent immuno-deficiency syndrome was reported to be low MBL level in blood. Deficiency of human MBL is caused by mutations in the coding region of the MBL gene. Rat homologue gene of human MBL gene was used to study functions of wild type and mutant MBL proteins. Although extensive studies have yielded the structural information of MBL, the functions of MBL, especially mutant MBL, still require investigation. We previously reported the cloning of rat wild-type MBL gene and the production of a truncated form of MBL protein and its antibody. Here, we present the cloning of mutant MBL cDNA in collagen-like domain (R40C, G42D, and G45E) using site-directed mutagenesis and differential behaviors of wild type and mutant MBL in cells. The major difference between wild type and mutant MBL was that while wild type MBL was secreted, mutant MBL was inhibited for secretion, retained in endoplasmic reticulum, and still functioned as a lectin.

Fracture Characteristics of Ductile Fiber Reinforced Cement based Composites by Collision of Steel Projectile (비상체의 충돌에 의한 고인성 섬유보강 시멘트복합체의 파괴특성)

  • Nam, Jeong-Soo;Kim, Gyu-Yong;Kim, Hong-Seop;Kim, Jung-Hyun;Han, Sang-Hyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.4
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    • pp.92-100
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    • 2015
  • The aim of this study is to evaluate the fracture characteristics of ductile fiber reinforced cement based composites with 1.5 volume ratio of polyvinyl alcohol and steel fiber by high velocity impact of steel projectile. We used gunpowder impact facility to evaluate the fracture characteristics of ductile fiber reinforced cement based composites by collision of steel projectile, and the impact velocity was from about 150 to 1,000m/s. The results of evaluation on the fracture characteristics of ductile fiber reinforced cement based composites were penetration grade, which is the kinetic energy more than three times of no-fiber reinforced specimen (Plain). In addition, ductile fiber reinforced cement based composites did not occurred critical damage other than the debris. In the case of mass loss, Plain specimen was proportional to kinetic energy of steel projectile, while ductile fiber reinforced cement based composites was not significantly affected by kinetic energy of steel projectile. In particular, this tendency had a close relationship with the fracture characteristics of back side of specimens, and the scabbing inhibiting efficiency of PVA specimen was higher than S specimen. In the results of verifying relationship between front and back side calculated by local damage, scabbing occurred at the region close to the back side in the ductile fiber reinforced cement based composites unlike Plain specimen. Thus, in this study, we examined principal fracture behaviors of ductile fiber reinforced cement based composites under collision of steel projectile, and verified that impact resistance performance was improved as compared to Plain specimen.

Evaluation of the Bending Behavior of RC beam by Using Color-based Image Processing Method (색상에 기반한 영상분석기법을 이용한 콘크리트 거더의 휨 거동 분석)

  • Woo, Tae-Ryeon;Jung, Chi-Young;Kim, In-Tae;Lee, Jong-Han;Cheung, Jin-Hwan
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.24 no.4
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    • pp.48-54
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    • 2020
  • Cracks in reinforced concrete structures are the most common type of damage and are used as important analytical data to understand the fracture behavior characteristics of structures. Currently, there is a problem that most of the crack investigation relies on visual inspection, therefore many researchers have proposed image analysis techniques to improve the problem. In this study, we proposed a crack evaluation method to be applied at an indoor experimental level using image analysis method. The image analysis technique using color is for distinguishing a boundary surface between objects existing in an image, and is a method for separating similar colors into one region based on a predefined color. In this study, to improve the accuracy of image analysis, blue paint was applied to the concrete surface and bending experiments were performed. The image analysis method was able to measure the crack width with superior accuracy compared to the crack diameter, and at the same time, it was also possible to analyze the deflection of the beam. Both the crack and deformation were able to confirm the accuracy similar to the existing measurement method, and it was found that the image analysis method was very excellent in terms of applicability.

Objectives and Strategies of Government Health Promotion Policy (정부의 건강증진사업 목표 및 추진방향)

  • Lee, Jong-Gu
    • Proceedings of The Korean Society of Health Promotion Conference
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    • 2005.09a
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    • pp.3-32
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    • 2005
  • 정부의 건강증진사업은 국민의 건강수명 연장과 삶의 질 향상에 궁극적인 목적이 있다. 이는 건강 지지적인 환경을 조성하고 질병을 예방${\cdot}$관리하며 평생 건강서비스를 제공하고 건강한 생활양식을 형성하도록 함으로써 달성될 수 있는 것이다. 건강증진사업을 위한 기반으로 연구와 개발 강화, 법과 규칙의 조정, 기금과 인력과 같은 자원 확보는 필수적이다. 정부의 건강증진전략은 첫째 자원할당의 우선순위를 확보하는 것으로 건강증진, 질병 및 손상의 예방, 재활관련 사업에 더욱 많은 자원을 할당하는 것이며, 둘째로 국가차원의 건강증진 프로그램을 개발하여 실행하는 것이다. 포괄적인 생애주기별 건강증진 프로그램(건강증진종합계획)과 모아보건, 학교보건, 산업보건, 그리고 만성질환예방프로그램 등이 포함된 포괄적인 프로그램을 개발하여 실행하는 것이다. 셋째로, 건강증진기금을 공공보건을 위한 하부기반과 건강증진 프로그램에 투자함으로써 사업의 하부기반을 정비하는 것이다. 건강증진사업을 위한 하부기반으로는 정책과 위임사항을 들 수 있는데, 국민건강증진법과 국민건강증진종합계획, 2005년 6월에 서울시 의회를 통과한 건강도시추진위원회를 들 수 있다. 정부의 건강증진사업의 법적 기반은 1995년에 제정된 국민건강증진법이다. 국민건강증진법은 국민들이 건강에 대한 가치를 인식하고 책임의식을 함양하며, 올바른 건강지식을 갖고, 국민들이 건강한 생활양식을 실천할 수 있는 환경 조성을 목적으로 하고 있다. 건강증진사업은 대중을 위한 보건교육과 건강상담, 영양관리, 구강보건관리, 질병의 조기발견과 치료를 위한 건강검진, 지역사회 건강문제에 관한 조사와 연구, 담배소비 감소와 건강증진부담금 부과를 통한 국민건강상태의 향상을 위한 사업이다. 훈련과정으로는 보건복지부에서 2005년부터 수행하고 있는 시와 지역을 위한 현장관리 프로그램과 서울시가 수행예정인 지역수준의 지도자 훈련과정이 있다. 건강증진사업의 원활한 진행을 위한 기금조성은 건강증진기금이 담배세로부터 조성되고 있으며 2004년 12월 31일 현재 담배 한 갑 당 500원으로 인상되어 부과되고 있다. 기금의 관리와 운용은 보건복지부가 담당하며, 기금은 건강한 생활양식형성에 대한 지원활동, 국민을 위한 보건교육과 교육자료 개발, 건강증진과 만성질환에 대한 연구, 질병의 조기발견을 위한 건강검진, 구강보건관리활동에 사용되고 있다. 향후 건강증진사업 투자계획은 1단계 (98-02년)에는 사업기반조성기, 2단계(03-06년) 보건소사업발전기, 3단계(07-11년)통합사업정착기로 구성되고 2단계의 인프라구축에 사용될 투자 비율은 30%에서 3단계에 15%로 감소될 예정이며, 사업실행 영역은 50%에서 65%로 확대될 계획이다. 2005년 건강증진사업의 중점목표는 건강증진사업의 지방 분산화, 건강증진사업의 근거마련, 사회적 형평성의 달성에 있다. 건강증진사업의 지방분산화를 위해서는 중앙에 관리센터가 설치되어 기획과 평가, 연구와 개발, 현장관리 훈련을 담당하게 되고, 지역관리센터에서는 자치적인 보건소 중심 건강증진사업의 수행과 평가를 진행하게 된다. 건강증진사업의 근거마련을 위해서 효과가 입증된 사업에 우선순위를 두며, 기획과 평가위원회를 설치하고, 건강증진사업의 평가결과를 환류 할 수 있는 체계를 마련하는 것이다. 또한 건강증진포럼을 구성하며 현 건강조사 체계를 수정한다. 한편 형평성 제고의 측면에서는 저소득층, 노인, 장애인들과 같은 취약계층의 건강상태 향상을 위한 중앙정부와 지방자치단체의 역할을 강화하고, 지역간${\cdot}$사회적 집단 간의 건강증진사업관련 형평성을 제고한다.

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Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells (백서 태자 두개관세포에서 Ti-8Ta-3Nb 합금의 생체적합성)

  • Cho, In-Goo;Cui, De-Zhe;Kim, Young-Joon;Lee, Kyung-Ku;Lee, Doh-Jae
    • Journal of Periodontal and Implant Science
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    • v.36 no.4
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    • pp.849-861
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    • 2006
  • 타이타늄은 기계적 특성이 우수하고 생체적합성이 뛰어나 의료용 장비의 주 재료로 사용되고 있으며 타이타늄 보다 기계적 특성이 더 우수한 타이타늄 합금들(주로 Ti-6Al-4V와 Ti-6Al-7Nb 합금)도 개발되어 치과와 의료용 임플란트로 사용되고 있다. 그러나 타이타늄 합금 성분들 중 알루미늄 (aluminum)과 바나디움(vanadium)은 인체에 노출되면 세포손상과 신경계에 문제를 일으킬 수 있다. 따라서 인체에 독성이 없으면서 기계적 성질과 생체적합성이 우수한 타이타늄 합금의 개발이 필요하다. 최근 인체에 독성이 없는 성분들이 함유된 새로운 ${\beta}$ - 형태의 타이타늄 합금들이 개발되고 있는데, ${\beta}$ - 타이타늄 합금은 그 기계적 성질이 기존의 ${\alpha}+{\beta}$ 타이타늄 합금에 비해 우수하다고 알려져 있다. 최근 새로운 ${\beta}$ - 타이타늄 합금이 전남대학교 부설 타이타늄 연구소에서 개발되었다. 이 연구는 새로 개발된 ${\beta}$ - 타이타늄 합금의 생채 적합성을 세포 증식도, 알카리 인산 분해 효소 활성과 유전자 증폭을 통해 알아보고자 하였다. 그 결과는 다음과 같다; 1. Titanium-6aluminum-4vanadium (Ti-6Al-4V) 합금 표면애서의 세포 증식율은 Titanium-Titanium8Tantalum-3Niobium (Ti-8Ta-3Nb) 합금과 순수 타이타늄 표면에 비해 유의하게 낮았다(p<0.00l). Ti-8Ta-3Nb 합금 표면에서의 증식도는 순수 타이타늄 표면과 유사하였다. 2. Ti-8Ta-3Nb 합금과 순수 타이타늄에서 배양된 세포이 알카리 인산 분해 효소의 활성도는 Ti-6Al-4V 합금에서의 것보다 유의하게 높았다 (p<0.001). 3. 유전자 증폭 분석 결과, Ti-8Ta-3Nb 합금과 순수 타이타늄에서 collagen type I과 bone sialoprotein mRNA 가 유사한 수준으로 발현되었다. 이상의 결과는 생체 적합성 측면에서 Ti-8Ta-3Nb 합금과 순수 타이타늄의 차이가 없음을 보여주며 따라서 Ti-8Ta-3Nb 합금이 의학 및 치의학 영역에서 새로운 임프란트 재료로 사용될 수 있음을 의미한다.

Analysis of Practical Reasoning Processes Presented in Consumer Education of Technology & Home Economics Textbooks (기술.가정 교과서의 소비자교육에 반영된 실천적 추론 과정 분석)

  • Moon, Young-Hoon;Lee, Soo-Hee;Sohn, Sang-Hee
    • Journal of Korean Home Economics Education Association
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    • v.25 no.2
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    • pp.79-101
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    • 2013
  • This study examined how practical reasoning processes were reflected in the revised consumer education of technology & home economics textbooks in secondary schools. Twenty-four textbooks from secondary schools for 7th to 10th grades were analyzed. Areas of textbooks analyzed were introduction, body content, learning activity, and evaluation. Analysis criteria were extracted from the previous literature regarding contents and questions dealing with practical reasoning processes and revised by a researcher of this paper. The results and conclusions of this study are as follows. The results of the analysis of the practical reasoning processes showed that, across all grades, "contexts" was the most common element, and "alternatives and means" was the second most common elements. The elements of "consequences", "action and reflection" were less represented in the textbooks, with the exception of the learning activity part. The types of practical reasoning process reflected were classified either as the entire process of reasoning being reflected or some of the process being reflected, or included in the body content. Most of these were some of the process being reflected. Since there were a lot of concept-oriented statements rather than questions, more practical reasoning questions should be developed to increase the reasoning process. In addition, a need exists to develop a variety of ways to utilize the entire practical reasoning processes in the textbooks to help teachers apply the practical reasoning processes to their lessons.

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Smart Camera Technology to Support High Speed Video Processing in Vehicular Network (차량 네트워크에서 고속 영상처리 기반 스마트 카메라 기술)

  • Son, Sanghyun;Kim, Taewook;Jeon, Yongsu;Baek, Yunju
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.1
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    • pp.152-164
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    • 2015
  • A rapid development of semiconductors, sensors and mobile network technologies has enable that the embedded device includes high sensitivity sensors, wireless communication modules and a video processing module for vehicular environment, and many researchers have been actively studying the smart car technology combined on the high performance embedded devices. The vehicle is increased as the development of society, and the risk of accidents is increasing gradually. Thus, the advanced driver assistance system providing the vehicular status and the surrounding environment of the vehicle to the driver using various sensor data is actively studied. In this paper, we design and implement the smart vehicular camera device providing the V2X communication and gathering environment information. And we studied the method to create the metadata from a received video data and sensor data using video analysis algorithm. In addition, we invent S-ROI, D-ROI methods that set a region of interest in a video frame to improve calculation performance. We performed the performance evaluation for two ROI methods. As the result, we confirmed the video processing speed that S-ROI is 3.0 times and D-ROI is 4.8 times better than a full frame analysis.

Importance awareness and Compliance on Patient Safety for Nurses Working in Operating Rooms (수술실간호사의 수술환자 안전관리에 대한 중요성인지도와 실천이행도)

  • Kim, Joung-Soon;Kim, Ju-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.12
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    • pp.5748-5758
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    • 2011
  • The purpose of this study was to evaluate the perceived patient safety, type of errors related to patient safety, importance awareness and compliance on patient safety for operating room nurses and to identify factors influencing compliance. Data were collected using a structured questionnaire from 191 perioperative nurses. Data were analyzed using descriptive statistics, t-test, paired t-test, ANOVA, Pearson correlation coefficients, and multiple regression. The perceived patient safety score was 6.3 as moderate level. Types of errors were mostly happened in patient injury (39.8%), counts (18.4%) and infection control (17.5%). The level of compliance on patient safety was significantly lower than that of importance awareness (t=18.01, P<.001). Compliance on patient safety showed significantly positive correlations to importance awareness (r=.56, p<.001). Experience of patient safety education, experience of errors in colleague, job position and working experience in hospital explained 13.9% of variance compliance on patient safety(F=8.407, P<.001). In conclusion, Hospital should develop education program related to patient safety, encourage nurses to manage safety protocol and ensure cultivating patient safety culture in the perioperative practice setting.

Microstructure of Spider Booklung as Bio-indicator for Monitoring Environmental Asbestos Exposure (거미 서폐의 미세구조와 석면노출 환경의 모니터링을 위한 생물지표적 유용성 평가에 관한 연구)

  • Kim, Chang-Mo;Moon, Myung-Jin
    • Korean Journal of Environmental Biology
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    • v.32 no.1
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    • pp.49-57
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    • 2014
  • Orb-web spiders can be considered as an effective bio-indicative animal to monitor the ecological air pollution of certain habitat since they have limited shifting ability during their life spans. In this study we revealed the fine structural characteristics of booklung in the orb-web spider Nephila clavata, and its bio-indicative significance in the monitoring environmental asbestos exposure. The high resolution scanning electron microscopy results suggest that the cuticular spikes near the atrium could be act as an effective filtering structure for dust materials. Furthermore, inner cuticular spikes which protruded across the air sacs, have the functions not only sustaining appropriate respiratory volume of each air sac but also help to enhance respiratory capacity by maximizing the gross surface area for gas exchange. Interestingly, in spite of short exposure, the asbestose fibrils were effectively captured on the surface of the atrial cuticular spikes. Furthermore, histologic damages were observed due to penetration of asbestos fibrils through air sacs and fixed on the hemolymph space. In addition, although accumulated mass of hemocytes were observed near the fibrils, there were no asbestos bodies or coagulated hemocytes were found on the surface of the fibrils, This could be mainly due to the short exposure period towards asbestos. Briefly, these results indicate the spider's booklung could be valuable tool in the detection ecological air pollutants.