• Radiation Oncology Journal
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• v.20 no.1
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• pp.41-52
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• 2002

Purpose : 3D conformal radiotherapy, the optimum dose delivered to the tumor and provided the risk of normal tissue unless marginal miss, was restricted by organ motion. For tumors in the thorax and abdomen, the planning target volume (PTV) is decided including the margin for movement of tumor volumes during treatment due to patients breathing. We designed the respiratory gating radiotherapy device (RGRD) for using during CT simulation, dose planning and beam delivery at identical breathing period conditions. Using RGRD, reducing the treatment margin for organ (thorax or abdomen) motion due to breathing and improve dose distribution for 3D conformal radiotherapy. Materials and Methods : The internal organ motion data for lung cancer patients were obtained by examining the diaphragm in the supine position to find the position dependency. We made a respiratory gating radiotherapy device (RGRD) that is composed of a strip band, drug sensor, micro switch, and a connected on-off switch in a LINAC control box. During same breathing period by RGRD, spiral CT scan, virtual simulation, and 3D dose planing for lung cancer patients were peformed, without an extended PTV margin for free breathing, and then the dose was delivered at the same positions. We calculated effective volumes and normal tissue complication probabilities (NTCP) using dose volume histograms for normal lung, and analyzed changes in doses associated with selected NTCP levels and tumor control probabilities (TCP) at these new dose levels. The effects of 3D conformal radiotherapy by RGRD were evaluated with DVH (Dose Volume Histogram), TCP, NTCP and dose statistics. Results : The average movement of a diaphragm was 1.5 cm in the supine position when patients breathed freely. Depending on the location of the tumor, the magnitude of the PTV margin needs to be extended from 1 cm to 3 cm, which can greatly increase normal tissue irradiation, and hence, results in increase of the normal tissue complications probabiliy. Simple and precise RGRD is very easy to setup on patients and is sensitive to length variation (+2 mm), it also delivers on-off information to patients and the LINAC machine. We evaluated the treatment plans of patients who had received conformal partial organ lung irradiation for the treatment of thorax malignancies. Using RGRD, the PTV margin by free breathing can be reduced about 2 cm for moving organs by breathing. TCP values are almost the same values $(4\~5\%\;increased)$ for lung cancer regardless of increasing the PTV margin to 2.0 cm but NTCP values are rapidly increased $(50\~70\%\;increased)$ for upon extending PTV margins by 2.0 cm. Conclusion : Internal organ motion due to breathing can be reduced effectively using our simple RGRD. This method can be used in clinical treatments to reduce organ motion induced margin, thereby reducing normal tissue irradiation. Using treatment planning software, the dose to normal tissues was analyzed by comparing dose statistics with and without RGRD. Potential benefits of radiotherapy derived from reduction or elimination of planning target volume (PTV) margins associated with patient breathing through the evaluation of the lung cancer patients treated with 3D conformal radiotherapy.

• Journal of Korean Tunnelling and Underground Space Association
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• v.22 no.5
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• pp.591-610
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• 2020

Concrete with activated carbon and titanium dioxide (TiO₂) has been used to reduce the particulate matter (PM) in underground structures (e.g., tunnels) due to the high performance of nitrogen oxides (NOx) abatement. Damage (e.g. crack, spalling, or detachment) can be caused by the environmental and ageing effects on the surface of the particulate matter reduction concrete, installed on the tunnel lining. Therefore, it is important to evaluate the existence of spalling on the concrete surface for maintaining performance of NOx reduction. In this study, a basic research was performed for feasibility of spalling evaluation using electrical resistivity characteristics. Given the test results, the electrical resistivity was decreased as the ratios of activated carbon (0~15%) and TiO₂ (0~25%) were increased for specimens. Under a dry condition, electrical resistivity of cement specimens, mixed with activated carbon and TiO₂, was decreased up to 2.3 times, compared with the normal cement specimen. In addition, under saturation conditions (degree of saturation: 85~98%), electrical resistivity of cement specimens with activated carbon, was decreased up to 3.5 times, compared with the normal cement specimen. Regardless of the condition (dry or saturated), the difference of electrical resistivity values shows the range of 2.3~2.8 times between the mixing specimen (with activated carbon (15%) and TiO₂ (25%)) and the normal cement specimen. This study can help to provide basic knowledge for spalling evaluation using the electrical resistivity on the surface of the particulate matter reduction concrete in tunnels.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.5
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• pp.1765-1775
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• 2013

The application of FRP wire as a mean of improving strength and ductility capacity of concrete cylinders under axial compressive load through confinement is investigated experimentally in this study. An experimental investigation involves axial compressive test of three confining amounts of FRP wire and three concrete compressive strengths. The effectiveness of FRP wire confinement on the concrete microstructure were examined by evaluating the internal concrete damage using axial, circumferential, and volumetric strains. The axial stress-strain relations of FRP wire confined concrete showed bilinear behavior with transition region. It showed strain-hardening behavior in the post-cracking region. The load carrying capacity was linearly increased with increasing of the amount of FRP wire. The ultimate strength of the 35 MPa specimen confined with 3 layer of FRP wire was increased by 286% compared to control one. When the concrete were effectively confined with FRP wire, horizontal cracks were formed by shearing. It was developed from sudden expansion of the concrete due to confinement ruptures at one side while the FRP wire was still working in hindering expansion of concrete at the other side of the crack. The FRP wire failure strains obtained from FRP wire confined concrete tests were 55~90%, average 69.5%, of the FRP wire ultimate uniaxial tensile strain. It was as high as any other FRP confined method. The magnitude of FRP wire failure strain was related to the FRP wire effectiveness.

• Tunnel and Underground Space
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• v.18 no.6
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• pp.491-502
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• 2008

A certain range of the original ground around the tunnel should be preserved to ensure structural safety of the tunnel when other structures are made around the tunnel, and thus this range is defined as safety zone of the tunnel. The main points to ensure the stability of an existing tunnel when constructing a new tunnel in an inter-crossing area are distance between two tunnels, size of the new tunnel, excavation method for the new tunnel, ground condition around the tunnel, and lining type of the existing tunnel etc. When the new tunnel is excavated above the existing tunnel, the existing tunnel is likely to suffer deformation at a crown zone, damage of arching effect, and live load of the new tunnel etc. On the other hand, when the new tunnel is excavated below the existing tunnel, the existing tunnel is likely to be damaged due to settlement. This study has been made on the behavior of the existing tunnel by means of model test and numerical analysis when the new tunnel is excavated below the existing tunnel. Safety zone of the tunnel was estimated by the results of strength/stress ratio obtained from numerical analysis, and the movement of ground was estimated by the model test. The results of earth pressure, ground displacements, and convergence of the tunnel obtained from model test were compared with those of numerical analysis, and show a similar trend.

• Journal of Korean Society of Steel Construction
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• v.24 no.1
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• pp.101-108
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• 2012

The orthotropic steel deck bridge made by using relatively thin steel plate, and structural members such as transverse and longitudinal ribs, cross beam, etc. in the bridge are fabricated with complex shape by welding. Therefore, the possibility occurring deformation and defects by welding is very high, and stress states in the welded connection parts are very complex. Also, the fatigue cracks in orthotropic steel deck bridge are happening fromthe welded connection parts of secondary member than main member. However, stress evaluation for main members is mainly carried out in the design process of the bridge, detailed stress evaluation and characteristic analysis is not almost reviewed in the structural details which fatigue crack occurred. For the orthotropic steel deck bridge with open ribs which has been serviced for 29 years, in this study, the cause of fatigue crack is investigated and the fatigue safety of the bridge is examined based on fieldmeasurement by the loading test and real traffic condition. Also, structural analyses using gridmodel and detailed analysis model were carried out for the welded connection parts of longitudinal rib and diaphramthat fatigue crack occurred. Additionally, the behavior characteristics due to running vehicles were investigated by using influence area analysis for these structural details, and the occurrence causes of fatigue crack in the target bridge were clarified.

• Journal of the Microelectronics and Packaging Society
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• v.25 no.3
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• pp.49-53
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• 2018

Since various methods to form well-aligned nano-/micro- patterns are underlying technologies to fabricate next generation wearable electronic devices, many efforts have been made to realize finer patterns in recent years. Among lots of patterning methods, the present invention includes a nano-transfer printing (n-TP) process which is advantageous in that a processing cost is low and high-resolution patterns can be formed within a short processing time. We successfully achieved pattern formation of highly ordered Pt lines with line-width of 250 nm, 500 nm, and $1{\mu}m$ on transparent and flexible substrates. In addition, we analyzed the durability of the patterns, showing excellent stability of line-shape even after a physical and repeated bending test of 500 times using a bending machine. As a result, it is expected that a n-TP process is very useful for forming various metal patterns, and it is also expected to be applied to wiring and interconnection technology of next generation flexible electronic devices.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.32-38
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• 2020

Cargo train braking uses the pressure changes in the air braking pipe to operate the braking tightening and releasing service repeatedly. Air-braking release failure means partial braking caused by a failure of the variable load valve after the driver handling the brake release. This phenomenon causes wheel flaws while driving a wagon, resulting in wheel breakage or train derailment. This study developed the air-braking release failure proof valve considering the technical requirements of the railway operation corporations. In addition, a durability test of the valve was carried out using a braking performance simulator, and its operating performance was evaluated from the pneumatic history under cyclic braking conditions. The warranty life of this valve was assessed by performing 160,000 cycles of testing of 12 prototypes in accordance with the zero-failure test method, considering the number of braking cycles while driving the wagon. During the durability test, the pneumatic input time, output time, and release velocity were almost constant. The warranty life of this valve was 59,860 times the 95% confidence level, which means that it can be operated without trouble for four years when the valve is installed in the bogie of the wagon.

• Journal of the Korea Concrete Institute
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• v.24 no.3
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• pp.249-258
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• 2012

Integral and rigid frame bridges have advantages in bridge maintenance and structural efficiency by eliminating expansion joints and bridge supports. However, the detail of typical girder-abutment connection is rather complex and increases construction cost depending on construction detail. For the purpose of compensating disadvantages such as complexity and additional cost, a new type of bridge is proposed in this study, which improves the efficiency of construction by simplifying the construction detail of girder-abutment connection. The proposed bridge has the connection detail of steel girder and abutment integrated by prestressed PS bar installed in the connection. In this study, finite element analysis and fatigue load test are conducted to evaluate the fatigue capacity of the proposed girder-abutment connection. The results of the finite element analysis revealed that the possibility of the fatigue damage in the girder-abutment connection is very low. The results of the fatigue load test verified that the integrity of the girder and abutment connection is maintained after 2,000,000 cycles of fatigue loading.

• Journal of Oral Medicine and Pain
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• v.36 no.3
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• pp.177-185
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• 2011

Aims: The purpose of this study was to evaluate the relationship between temporomandibular joint pain and the relative signal intensity (RSI) of retrodiscal tissue on T1-, and T2-weighted MRI images. Materials and Methods: This study was based on 122 TMJs of 61 patients who complain of TMJ pain in only one side but were revealed to have disc displacement in both TMJs according to MRI findings. The signal intensities of regions of interest (ROIs) in retrodiscal tissues were measured using T1-, and T2-weighted MRI images. The RSIs of retrodiscal tissues were referenced to the signal intensities of the ROIs of brain gray matter. The relationships between the RSI of retrodiscal tissue and joint pain, joint effusion, condylar degenerative change, and degree of disc displacement were examined. In addition, the relationships between joint pain and joint effusion, condylar degenerative change, and degree of disc displacement were examined. Results: On T1-weighted MR images, the painful TMJs showed significantly higher retrodiscal tissue RSI than non-painful TMJs. In addition, there is an association between joint pain and the degree of disc displacement. However, on T2-weighted MR images, the RSIs of retrodiscal tissues didn't show any significant differences with regard to joint pain, joint effusion, condylar degenerative change, and degree of disc displacement. Conclusions: The signal intensity of retrodiscal tissue can be used as a diagnostic marker for painful TMJ. However, the overall results suggest the signal intensity of retrodiscal tissue has a limited diagnostic significance in determining the pathologic status of TMJ.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.94-101
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• 2016

Objectives : Anemia is a common problem in the management of elderly patients. Recent studies reported that anemia was associated with cognitive impairment and Alzheimer's disease. This study was aimed to analyze the differences of hemoglobin levels in Korean patients with Alzheimer's disease(AD) dementia, mild cognitive impairment(MCI), and healthy controls. Furthermore, the study also examined if any association between hemoglobin levels and cognitive functions existed. Methods : A total of 116 Korean elderly adults were participated in this study(mean age 74.67 years ; 60.3% female). The Korean version of the Mini-Mental State Examination(MMSE-K), Clinical Dementia Rating(CDR) and Global Deterioration Scale(GDS) were applied to all subjects. Hematological and related blood chemistry values were investigated. Results : We found that patients with AD dementia had significantly lower hemoglobin and hematocrit levels than MCI subjects and healthy control group. The hemoglobin levels showed a positive correlation with MMSE-K and negative correlation with CDR, GDS. Conclusions : Among Korean elderly, low hemoglobin level is associated with a cognitive impairment. This study indicates that AD is associated with anemia, and low hemoglobin levels may contribute to potentially useful clinical markers of AD. The risk factor for dementia needs to be confirmed by prospective longitudinal studies in a larger group of patients.