• Tunnel and Underground Space
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• v.33 no.5
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• pp.388-398
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• 2023

The changes in groundwater flow due to mining development act as a contributing factor to major issues such as ground subsidence, strength reduction and collapse. For the sustainable mining development, measures for dealing with fluctuations in seasonal underground water inflow, power losses, pump damage, and unexpected increases in inflow must be put in place. In this study, the aim is to identify the causes of underground seepage through the examination of hydrological connectivity between the study area and nearby limestone mine. A tracer tes for assessing subsurface connectivity has been planned. A variety of tracers, such as dyes and ions, were applied in lab test to select the optimal tracer material, and a hydrological model of the study area was implemented through field test. Finally, the hydrological connectivity between the external stream and underground water in the mine was analyzed.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.37 no.2
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• pp.103-110
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• 2024

In this study, a nonlinear dynamic analysis of a frame and single member, which reflect the characteristics of a plant facility, is performed using the commercial MIDAS GEN program and the results are analyzed. The general structural members and material properties of the plant are considered. The Newmark average-acceleration numerical-analysis method is applied to a plastic hinge to study material nonlinearity. The blast load of a vapor-cloud explosion, a representative plant explosion, is calculated, and nonlinear dynamic analysis is conducted on a frame and single member. The observed dynamic behavior is organized according to the ratio of natural period to load duration, maximum displacement, ductility, and rotation angle. The conditions and range under which the frame functions as a single member are analyzed and derived. NSFF with a beam-column stiffness ratio of 0.5 and ductility of 2.0 or more can be simplified and analyzed as FFC, whereas NSPF with a beam-column stiffness ratio of 0.5 and ductility of 1.5 or more can be simplified and analyzed as FPC. The results of this study can serve as guidelines for the blast-resistant design of plant facilities.

• Neonatal Medicine
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• v.18 no.1
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• pp.59-69
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• 2011

Purpose: Current studies have demonstrated the neuroprotective effects of 6-cyano-7-nitroquinoxalin-2,3-dione (CNQX) in many animal models of brain injury, including hypoxic-ischemic (HI) encephlopathy, trauma and excitotoxicity, but limited data are available for those during the neonatal periods. Here we investigated whether CNQX can protect the developing rat brain from HI injury via mediation of nitric oxide synthase. Methods: In an in vivo model, left carotid artery ligation was done in 7-day-old Sprague-Dawley (SD) rat pups. The animals were divided into six groups; normoxia (N), hypoxia (H), hypoxia with sham-operation (HS), hypoxia with operation (HO), HO treated with vehicle (HV), and HO treated with CNQX at a dose of 10 mg/kg (HC). Hypoxia was made by exposure to a 2 hr period in the hypoxic chamber (92% $N_2$, 8% $O_2$). In an in vitro model, embryonic cortical neuronal cell culture of SD rats at 18-day gestation was done. The cultured cells were divided into three groups: normoxia (N), hypoxia (H), and hypoxia treated with CNQX (HC). The N group was prepared in 5% $CO_2$ incubators and the other groups were placed in 1% $O_2$) incubators (94% $N_2$, 5% $CO_2$) for 16 hr. Results: In the in vitvo and in vivo models, the expressions of iNOS and eNOS were reduced in the hypoxia group when compared to the normoxia group, whereas they were increased in the CNQX-treated group compared to the hypoxia group. In contrast, the expression of nNOS was showed reversely. Conclusion: CNQX has neuroprotective property over perinatal HI brain injury via mediation of nitric oxide synthase.

• Korean Chemical Engineering Research
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• v.55 no.6
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• pp.837-845
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• 2017

A recirculating integrated system composed of a fluidized biofilter filled with waste-tire crumb media fixed with return sludge from wastewater treatment facility of D dyeing industrial center, and a UV/photocatalytic reactor packed with calcined $TiO_2$ coated-glass beads as photocatalyst-support, was constructed and was run to treat authentic textile-dyeing wastewater from D-dyeing industrial center, which was mixed with an alkaline polyester-weight-reducing wastewater and a wastewater from sizing process. As a result, its total removal efficiency(RE(tot)) of $COD_{cr}$ and colors were ca. 81% and 55%, respectively. The synergy effect of the recirculating integrated system to enhance total removal efficiency(RE(tot)) of $COD_{cr}$ and colors were evaluated at most ca. 7% and 3%, respectively. The fluidized biofilter and the UV/photocatalytic reactor were responsible for ca. 94% and 6% of the total $COD_{cr}$ removal efficiency, respectively, and were also responsible for ca. 86% and 14% of the total color-removal efficiency, respectively. Thus, the degree of the UV/photocatalytic reactor-unit process's contribution to RE(tot) of color, was about 2.4 times of that to RE(tot) of $COD_{cr}$. Therefore, the UV/photocatalytic reactor facilitated the more effective elimination of colors by breaking down the chemical bonds oriented from colors of dyes such as azo-bond, than $COD_{cr}$. In addition, the effect of the removal efficiency of each unit process(i.e., the fluidized biofilter or the UV/photocatalytic reactor) of the recirculating integrated system on RE(tot) of $COD_{cr}$ and colors, was analysed by establishing its model equation with an analytic correlation.