• Journal of Adhesion and Interface
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• v.18 no.1
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• pp.13-24
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• 2017

In this study, nanoparticles which encapsulated hydrophobic antimicrobial compounds with 50wt% of payload and 70%of solid content were prepared. These nanoparticles could be dispersed at water as well as various medium. Water dispersible organic-inorganic (O-I) hybrid nanoparticles were first prepared using alkoxysilane-functionalized amphiphilic polymer precursors through a conventional sol-gel process. Hydrophobic antimicrobial compound, Eugenol encapsulated nanoparticles were prepared using these O-I hybrid nanoparticles through a new nanoprecipitation process. The effect of various preparation on the size of nanoparticles, amount of payload, antimicrobial activity, and release rate of encapsulated compounds was investigated. All eugenol-encapsulated O-I nanoparticles regardless of preparation condition showed the same minimal inhibitory concentration (MIC) (50mg/ml) and 99% of antimicrobial activity for every strain. Their antimicrobial activity could maintain longer than two weeks. Especially, eugenol-encapsulated O-I nanoparticles prepared using tetraethoxysilane (TEOS) exhibited the highest payload (50wt%) and the lowest release rate which was owing to higher inorganic content in the O-I nanoparticles. And these O-I nanoparticles dispersed in hexanediol (HD) showed the highest antimicrobial activity and solid content (70wt%) because HD acted as a solvent as well as a antimicrobial agent.

• Journal of Science and Technology Studies
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• v.8 no.2
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• pp.109-135
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• 2008

This paper alms to analyze gender sensitiveness of national R&D projects-in the field of health- in Korea and to find a new policy which can enhance gender sensitiveness. From the gender sensitive perspective, the gender unbalanced participation in scientific research should be reconsidered, and the result of research also has to be gender balanced. In advanced countries such as european countries or United states, gender sensitive research are enforced in various ways. The NIH developed guidelines on the inclusion of women in clinical research, while the Health Canada invented a new evaluation tool of gender sensitiveness in researches. The analysis of gender sensitiveness in korean national R&D programmes showed that low number of women researchers involved in national R&D programmes, one gender oriented research subjects, and ignorance of women's specific interest in research programmes should be reconsidered and changed. In order to Improve the korean situation, not only a selection process, but also an evaluation process of performed programmes should be developed and implemented.

• Journal of the Korean Chemical Society
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• v.54 no.1
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• pp.137-141
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• 2010

Generally, polymer materials are not air-permeable and hydrophilic. In addition, they do not possess anti-fungal property. Hydrophilicity, air-permeability, and anti-fungal properties of new composites consisting of polymer, ceramic nanoparticles, and silver ion were investigated by contact angle measurements, air permeation time, and cell culture. The hydrophilic, air-permeable, and anti-fungal composites can be used in health care industry.

• Review of KIISC
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• v.28 no.3
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• pp.18-25
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• 2018

최근 블록체인 기술을 응용한 가상화폐에 대한 관심이 높아지면서 자본금이 많지 않은 사람들도 블록체인 네트워크에 참여하기 시작했다. 가장 유명한 가상화폐인 비트코인이 채택한 PoW 방식은 고성능 하드웨어의 과열된 열풍을 불어왔고 PoS 방식은 기존 지분이 많은 참여자들이 많이 존재하여 소수의 자본금을 가진 신규 참여자들이 네트워크에 새로 참여하기 어려운 환경이다. 따라서 본 논문에서는 기존 블록체인 증명방식인 PoW, PoS 방식보다 네트워크 참여를 위한 자본금이 적고 신규로 참여하더라도 리스크가 적은 PoP(Proof-of-Probability) 방식을 소개한다. PoP 방식은 블록을 생성할 시 실제 암호화된 해쉬와 수많은 가짜 해쉬를 각 노드들이 정렬하여 진짜 해쉬를 복호화하여 찾은 노드가 블록을 생성하는 방식이다. 또한 1개의 해쉬를 복호화하여 검증받을 때 1분의 대기시간을 두어 과열된 컴퓨팅파워 경쟁을 제한한다. 지분(Stake)이 많을수록 블록을 생성할 확률은 높아지지만 이는 PoS 방식처럼 절대적이지 않다. 이 방식을 이용한다면 지분을 많이 가진 유효성 검증자(Validators)에 의한 집중화를 피하며 블록체인 네트워크에 참여하려는 진입장벽도 낮출 수 있을 것 이다.

• Membrane Journal
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• v.24 no.4
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• pp.301-310
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• 2014

In this study, the silica nanoparticles were considerably chosen to improve a dimensional stability, proton transport and electrochemical performance of the resulting inorganic-organic nanocomposite membranes. For this purpose, hydrophobic silica (Aerosil$^{(R)}$ 812, Degussa) and hydrophilic silica (Aerosil$^{(R)}$ 380, Degussa) nanoparticles were, respectively, introduced into a Sulfonated poly(arylene ether sulfone) (SPAES) polymer matrix. The $SiO_2$ particles are evenly dispersed in a SPAES matrix by the aid of a non-ionic surfactant (Pluronics$^{(R)}$ L64). A $SiO_2$ content plays an important role in membrane microstructures and membrane properties such as proton conductivity and water uptake. Therefore, to study nanocomposite membranes with excessive amount of silica, the content of silica nanoparticles were increased up to 5 wt%. Interestingly, a hydrophobic $SiO_2$ containing nanocomposite membrane showed better electrochemical performance (29% higher than pristine SPAES) despite of low proton conductivity due to its adhesive properties with a catalyst layer in a single cell test. All the silica-SPAES membranes exhibited better performance than a pristine SPAES membrane.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.196-196
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• 1994

DDS에 활용될 수 있는 고분자 소재를 개발할 목적으로 물성 및 응용성이 우수한 고분자 겔에 관한 연구를 수행하였다. Ethylene oxide,propylene oxide 각각의 copolymer인 poloxamer등의 prepolymer들을 triisocyanate로 가교시키고 diisocyanate 로 chain이 연장된 "soft hydrogel"을 제조하였다. 모델 약물을 선정하여 crosslinker와 extender의 조절에 따른 hydrogel의 약물 방출 조절능을 조사하였으며 그 기전을 규명하고자 하였다. 가교부위에 urethane bond를 함유한 soft hydtogel은 건조상태에서도 고무와 같은 전연성을 보여 일반적인 hydrogel과 대비되는 특성을 보였으며 이에 따른 다양한 활용성이 기대되었다. Extender및 crosslinker의 비율에 따라서 이 rubber elasticity가 조절되었다. 가교도가 감소할수록 팽윤도가 상승하였고 이에 따른 약물방출도 증가함을 확인하였다. 또한 Prepolymer의 분자량 및 친수/소수성등의 물성에 따라 약물방출을 조절할 수 있었다. 제조된 hydrogel에 조절방출시 필요한 기능을 부가시키고자 poly(carylic acid)류와 IPN 공중합체를 합성하여 물성을 조사하였고 비이온성/양이온성/음이온성 모델약물을 선정하여 pH에 따른 가변적 팽윤도와 이온성 상호작용등에 근거한 약물 조절방출기전을 조사하였다.기전을 조사하였다.

• The Korean Journal of Archival Studies
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• no.31
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• pp.3-42
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• 2012

This paper considers some possibilities of community archives by exploring the concepts ans meanings of archival description. The author deals with two interesting cases -Herstory Writers Workshop Collection of Stony Brook University in New York and Poolmoo Collection of Poomoo Agricultural School in Korea. The author argues that archivists should know the specifications of Community Archives related to National Archives when they organizing and preserving records and archives of community archives.

• Journal of the Korean GEO-environmental Society
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• v.15 no.3
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• pp.15-19
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• 2014

Spilling pollutants and its contamination to the ground have serious impact to public resulting in various research about remediation techniques. In this study, the use of amphiphilic block copolymer for remediation was investigated with a series of laboratory tests on removal of hydrophobic contaminant in soil. Four types of amphiphilic block copolymer were developed and the efficiency of the cleaning was compared with surfactant using arbitrary diesel-contaminated soils. The results of the study show that the use of amphiphilic polymer in the soil washing process significantly enhanced the remediation of the contaminated soil and a potential of new methodology of eco-friendly remediation.

• Korean journal of communication and information
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• v.23
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• pp.189-221
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• 2003

This study compares the influence of perceived public opinion on Internet users' willingness to expression in real space with in cyber space. In real space, people who perceive their opinions as minority opinion are reluctant to express theirs publicly because of fear of isolation. But cyber space is the anonymous world. So we can expect that people express their opinions freely without the fear of isolation in this space. This study's results provide the support for our expectation. In cyber space, the minority perception group has as the high willingness to expression of their opinion about the abrogation of the Korean Family Rights Raw as the majority perception group. Both of in cyber space and in real space, it is the perception failure group that makes discrepancy in the willingness to expression. This group has the lowest willingness to expression in both space. However, the other predictors of willingness to expression in cyber space are similar to those in real space. Issue salience, Communication apprehension, and Age are the very significant predictors of willingness to expression in both spaces. Sex and ideology are significant predictors in real space, while the frequency of online conversation is the significant predictor in cyber space.

• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2002.10a
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• pp.31-42
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• 2002

최근 지하철 터널은 사용자 편의성, 도심지 접근성 및 원활한 교통처리 등을 고려하여 지반조건이 불리한 상황에서도 터널로 계획되는 경우가 많아지고 있다 따라서 시공중의 터널안정성확보, 굴착에 따른 인접구조물의 침하영향, 발파진동영향 등을 종합적으로 고려한 지보패턴 및 보조·보강공법의 결정이 매우 중요하나 정량적인 판단기준의 부재로 인하여 주로 경험적인 설계에 의존하는 경우가 많다. 본 연구에서는 도심지 지하철 터널의 복합적인 거동특성을 고려하기 위하여 여러 가지 예상위험요소의 정량화 방안을 제안하고, 다변량 통계분석기법을 활용하여 여러 가지 위험 요소들의 특성을 함축적으로 나타내는 소수의 총합적인 지표(안정성인자, 환경성인자)로 대표화 할 수 있음을 검증하였다. 안정성 인자 및 환경성 인자를 이용한 서울시 지하철 00공구 설계사례를 통해 정량화지표(Multiple Index)의 터널설계에의 적용성을 평가하고 이의 설계시 활용방안을 제안하고자 하였다.