• Childhood Kidney Diseases
• /
• v.3 no.2
• /
• pp.109-116
• /
• 1999

Purpose: Insulin-like growth factor(IGF)-I and -II are peptide growth factor whose activity is modulated by interaction with the family of six IGF-binding proteins(IGFBPs). IGF-I is detected in rat kidney and has metabolic and growth effects. This study was designed to examine temporal expression of IGFBPs in kidney during renal development and postischemic regeneration in rat. Method: The expression of IGFBPs in kidney during renal development from 15th day of gestation to adult life by using Northern blot analysis. We also examined the renal IGF-IGFBP axis in uremic rat by using Northern blot and immunohistochemistry. Results: The mRNA of IGFBP-1 and -3 were not or barely detected in fetal stages. However, the mRNA level of IGFBP-1 and -3 were increased gradually from day 7 after birth to adult. In contrast, the mRNA of IGFBP-2 and -5 were highly expressed in fetal stages and maintained almost same levels until day 7 (IGFBP-2) or day 30 (IGFBP-5) after birth, then their levels decreased markedly. The mRNA of IGFBP-4 were expressed moderately in fetal kidney and increased gradually after birth. Interestingly, the mRNA of IGFBP-1 and-4 were induced up to 3-5 fold during maximum regeneration period and were recovered to normal levels after acute ischemic injury. In contrast, the mRNA level of IGFBP-3 and-IGFBPrP-1 were decreased slightly at 1 day after ischemic injury, then recovered to normal level during maximum regeneration period. Conclusion: There were differential expressions of IGFBPs in kidney that can modulate IGF action on developing, differentiating, maintaining, and regenerating renal structure and function.

• Journal of Animal Science and Technology
• /
• v.49 no.1
• /
• pp.59-66
• /
• 2007

Sixty-seven Hanwoo calves were allocated into two groups, 27 spring calves (SC) and 40 fall calves (FC) to investigate the effects of calving season on water and nutrient intakes, growth performance and disease occurrence for the nursing and the post-weaning period. Mean DMI of 3 to 4 mo old FC was lower than that of SC due to low temperature in winter for FC. Water intake was higher for FC (birth to 1 mo old) but lower for SC (2 to 4 mo old) than the others. Mean BW did not differ between SC and FC, but average daily gain for over 2 mo old SC were significantly higher than FC. Diarrhea was mainly observed when the calves were before 60 d old; in particular, it occurred more frequently for less than 30 d old FC compared with SC. The present results indicate that calving season may affect water intake, feed intake and growth performance of Hanwoo calves.

• Clinical and Experimental Pediatrics
• /
• v.52 no.2
• /
• pp.242-246
• /
• 2009

The clinical features of ring chromosome 13 include mental and growth retardation, CNS anomalies, facial dysmorphism, cardiac defects, genital malformations, limb anomalies, skeletal deformities and anal malformations. Although many cases of ring chromosome 13 have been reported worldwide, only 6 cases have been reported in Korea, and the latter cases were not mosaic but pure ring chromosome 13. Here we report a case with mosaic ring chromosome 13. The baby boy was born at 37 weeks of gestation by induced vaginal delivery due to intrauterine growth restriction (IUGR). He was the second baby of a 28-year-old hepatitis B carrier mother and a 32-year-old father. There was no family history of chromosomal anomalies. The baby was a symmetric IUGR with a birth weight of 1,860 g, length of 44.8 cm, and head circumference of 29.4 cm. The physical examination revealed microcephaly, trigonocephaly, flat occiput, large ears, short neck and dysmorphic facial features, including microophthalmia, hypertelorism, antimongoloid slanting palpebral fissures, a flat nasal bridge, and micrognathia. The karyotype of this patient performed by peripheral blood lymphocytes was 46,XY,r(13)(p13q34)/45,XY,-13/46,XY,dic r(13;13)(p13q34;p13q34). The baby showed failure to thrive, hypotonia, and developmental delay. We report the first case of mosaic ring chromosome 13 in a male baby in Korea and compare this case with other Korean cases of non-mosaic ring chromosome 13.

• Journal of Nutrition and Health
• /
• v.25 no.2
• /
• pp.187-199
• /
• 1992

The purpose of the study is to assess and evaluate methods employed in nutrition surveys and to give an information on methodological considerations for future studies in Korea. Three hundred thirty six papers of nutritional surveys published from 1960 to 1990 were classified into 9 groups according to the survey subject and analyzed for methods used in survey. The frequency of publications according to the survey subject was as the following order : 'in-fants and preschool children' 'school age children' 'adolescence' 'college students' 'preg-nant and lactating women' 'housewives' 'the elderly' 'workers' and 'patients' Eighty five percents of papers applied methods of dietary assessment. of which weighing method recall method an record method were extensively used in the order. Questionnairs included items related to nutrition such as food habit nutrition knowledge etc. Anthropometric techniques were employed in 53% of papers and in general growth measurement were undertaken for children and body composition was emphasized for adults. biochemical assessment was limited to 32% of papers and assessment of anemia was the major test. Clinical studies were applied to 26% of the studies. of which only 5% employed examination of clinical signs of malnutrition Recently self-reported health status assessed using questionnaires has been adopted frequently. Further researches are required for evaluation of the methods employed in nutrition surveys in order to develop the standard model for nutrtion survey so that obtained data can become more reliable and utilized efficiently.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.32 no.1
• /
• pp.109-118
• /
• 2005

In the field of pediatric dentistry, comparison and analysis of cephalogram values of children are important fir evaluation of growth and development, and are essential to evaluate the craniofacial form and growth pattern for early diagnosis of malocclusion. For this, cephalographic norm values are important, but not many studies on the primary dentition exist. To compare the past norm values of normal occlusion in the primary dentition with current norms, preschool children, 4 to 5 years of age, with normal occlusion in the primary dentition who visited our hospital were examined. Among these children, 46 children with normal facial form and developmental status were chosen for evaluation of cephalogram values. The following results were as follows: 1. For skeletal values, the angular values showed no significant differences between males and females, and the linear values were generally greater in males than females. 2. SNA was $81.3^{\circ}$, SNB was $76.6^{\circ}$ and ANB difference was $4.7^{\circ}$. 3. The ratio for Mandibular body length to Anterior cranial base length was 0.9 : 1 for both male and female and the ratio for posterior facial height to anterior facial height was 61.4 % for male, 62.0 % for female. 4. For dental values, IMPA was $84.2^{\circ}$ and UA to SN was $90.8^{\circ}$. 5. The upper lip to Ricketts esthetic line was positioned 2.6 mm anteriorly, and the lower lip to Ricketts esthetic line was positioned 2.5 mm anteriorly.

• Korean Journal of Health Education and Promotion
• /
• v.14 no.1
• /
• pp.161-172
• /
• 1997

In order to assess the physical growth and development, and nutritional status of primary, middle and high school students in the city of Seoul, physiques of 4, 041 persons(Male : 2, 096, Female: 1, 945) were measured from March 1 to July 31 in 1995 and variouis physical and nutritional indices, maximum growth age related to them were calculated. The results are as follows: 1. Physical Growth and Development The growth of body height showed straight linear development among male in the ages 7~16 and among female 7~14, and after that showed slower development. The age of cross over between two sexes was between 11.5 to 12.5 years of age. The maximum growth age was between 11 and 12 years of age(7.28cm) in male and between 11 aqnd 12 years of age(9.77cm) in female. In terms of body weight, it also showed straight linear development among male in the ages 7~16 and among female 7~14, and after that showed slower development. The maximum growth age was between 11 and 12 years of age(7.64kg) in male and between 11 and 12 years of age(8.l9kg) in female. In terms of chest girth, it showed two step development among male in the age of 7~13 and 13~17, and among female in the age of 7~14 and 14~17. The age of cross over between two sexes was 11 and 12 years of age. In terms of sitting height, it showed two step development in the age of 7~14 and 14~17 of both sexes and the age of cross over between two sexes was between 10.5 to 14.5 years of age. The maximum growth age was between 11 and 12 years of age(3.64cm) in male and between 11 and 12 years of age(5.98cm) in female. 2. Maximum Growth Age of Physical Growth and Development In body height, MGA was 10.59 for male and 10.34 for female which showed that MGA for both sexes appeared in similar periods. In body weight, MGA was 10.30 for male and 10.30 for female which showed that MGA for both sexes appeared in similar periods. In chest-girth, MGA was 14.74 for male and 11.60 for female which showed that MGA for female appeared about 3 years earlier than for male. In sitting height, MGA was 11.69 for male and 11.38 for female which showed that MGA for both sexes appeared in similar periods. Maximum growth ages of physiques appeared in order of body height 〉 body weight 〉 sitting height 〉 chest-girth.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.33 no.4
• /
• pp.699-703
• /
• 2006

The purpose of this study was to analyze the parental consultations, patients' age and consulters. Also it was to improve the tendency of consultation homepage The subjects were 2485 questions on Korean Academy of Pediatric Dentistry Homepage except deleted questions which were not related with consultations. The examined contents were categorized into patients' age, counseling contents, consulters. The results were as follows: 1. Patients mostly belonged to preschool children(64.29%). 2. In the subjects, questions were mostly about growth and development, restorative and pulp treatment. 3. In the subdivided subjects, great part of questions were about tooth eruption, restorative and pulp treatment and trauma. 4. The 93.72% of consulters were mothers. 5. We should reinforce with FAQ about growth and development, restorative and pulp treatment and trauma. Also we should improve on quality of information and childcare related contents and Homepage related pediatric dentistry.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.11 no.2
• /
• pp.122-129
• /
• 2008

Purpose: Patients with chronic gastrointestinal disease are at risk for trace element deficiency due to impaired absorption and gastrointestinal loss. The aim of this study was to evaluate the trace element status of patients with gastrointestinal disease by blood and hair analysis, and to determine the usefulness of hair mineral analysis for diagnosing trace element deficiency not detected by a blood test. Methods: An analysis of hair minerals was performed and compared with blood mineral analysis in 13 patients with chronic gastrointestinal disease. The concentration of each element in the hair and blood was compared in the subgroups based on parenteral nutritional support or clinical symptoms. Results: Almost all patients had trace element deficiency. The trace elements deficient in the blood or hair analysis included zinc, selenium and copper. The hair zinc concentration was significantly lower in the group receiving parenteral nutritional support. The hair selenium concentration was statistically associated with the clinical symptoms of hair loss, brittle hair and loss of hair pigmentation. Conclusion: The results of this study suggest that patients with chronic gastrointestinal disease should receive adequate zinc and selenium replacement to avoid trace element deficiency especially when treated with long-term parenteral nutrition. Hair mineral analysis is useful as a complementary tool for the detection of a trace element deficiency.

• Parasites, Hosts and Diseases
• /
• v.27 no.1
• /
• pp.57-66
• /
• 1989

A scanning electron microscopic study was performed to observe the tegumental ultrastructures of Paragonimus iloktuenensis according to its developmental stages. The metacercariae were obtained from the liver of the brackish water crab, Sesarma dehaani. Juvenile and adult p. iloktsuenensis were recovered from the experimental rats on 2, 4 and 8 weeks after infection. The findings were summarized as follows: 1. The encysted metacercariae were charaeteristically gourd-shape, with their whole body surface beset with numerous spade-shape spines. The Barge, type II sensory papillae (non-ciliated round swellings) were arranged along the rim of the oral and ventral suckers, 11~12 and 6~8 in numbers respectively, 2. Two-week old juvenile worms, recovered chieay from the liver of the experimental rats, were slender in body shape: with their ventral sucker near the anterior one-third level. The distribution of tegumental spines was less dense than in the encysted metacercariae. The spines were with 1~2 pointed tips and 3~.4 longitudinal splits. Numerous ciliated knob-like, type I papillae were observed in both sides of the oral sucker, and 6 large, type If papillae were arranged along the rim of the ventral sucker. 3. Four week old worms, recovered from the thoracic cavity and/or lung parenchyme of the experimental rats, were thicker than wide in body configuration, and their ventral sucker was located near the anterior one.fourth level. The tegumental spines at ventral surface were grouped, each group with 3~5 aggregated ones. The type I and type II papillae (small-sired) were distributed chiefly around the rim of two suckers. 4. Adult (eight-week old) worms, recovered from the capsules in the lung parenchyme, were very stout, and covered densely with bearfoot like spines. At dorsal surface, cobblestone-like cytoplasmic processes were well-developed, with many tegumental spines embedded in them. It was observed in this study that the tegument of p. iloktsuenensis continued to change and differentiate as the worms grew to be adults.

• Korean journal of applied entomology
• /
• v.44 no.3 s.140
• /
• pp.189-197
• /
• 2005

Cellulose-digesting bacteria were isolated from hindgut of Allomyrina dichotoma (Coleoptera: Dynastidae). The bacterial isolates were identified as Yersinia sp. and Bacillus sp. The addition of the identified bacteria to diet increased growth rate of the cetoniid beetle, Protaetia brevitarsis senlensis (Coleoptera: Cetoniidae), probably by digesting cellulose nutrient contained in the oak tree sawdust diet. An additive of wheat flour at more than 10% to the sawdust diet significantly enhanced growth of P. brevitarsis senlensis. Trimmed branches of apple trees have been disposed in the apple farms and could be used for a diet component of the cetoniid beetle when the cellulose-digesting bacteria were mixed with the derived-sawdust. Resulting manure from mass rearing of P. brevitarsis senlensis contained high organic matters and trace amounts of toxic metals. When the manure were splayed on soil, it was effective as a natural compost and significantly stimulated lettuce growth. This research suggests a model technology to use cellulose-digesting bacteria to use for culturing grub, which results in natural recycles of trimmed branches in apple farms as grub diet, and to use grub manure as a natural compost.