• Geotechnical Engineering
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• v.13 no.1
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• pp.19-34
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• 1997

Applications of geostatistical method to cone penetrometer data have been performed at the overconsolidated clay site. Randomlylocated 28 electronic CPT soundings (Location A) and consistently-located 38 CPT soundings(Location B) are investigated geostatistically. Variograms for Locations A and B have been developed for q, from the CPT data by using "kriging" principles, which establish the horizontal and vertical correlation distrances at this site. These vertical and horizontal correlation distances can be used to optimal sampling design, where, if one needs to compare two test results, sampling must be made within these vertical and horizontal correlation distances. Analysis of the variograms indicated that the geological formation between two locations are not very different in both vertical direction and horizontal direction.direction.

• Korean Journal of Clinical Pharmacy
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• v.19 no.1
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• pp.50-60
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• 2009

Highly variable drugs (within-subject variability greater than 30%) have been difficult to meet current regulatory acceptance criteria using a reasonable number of study subjects. In this study, we reviewed previous studies presenting alternative approaches for bioequivalence evaluation of highly variable drugs, and focused on an approach for widening the bioequivalence acceptance limits using within-subject variability. We discussed the suggested five solutions for highly variable drug including the deletion of $C_{max}$ of the bioequivalence criteria, direct expansion of bioequivalence limit, multiple dose studies in steady state, bioequivalence assessment on the metabolite, add-on study, and widening the bioequivalence acceptance limits based on reference variability. The methods for widening of bioequivalence limits based on reference variability are scaled average bioequivalence containing within-subject variability on reference drug (${\sigma}_{WR}$), population bioequivalence derived from total variability on reference drug (${\sigma}_{TR}$) and test drug (${\sigma}_{TT}$), and individual bioequivalence derived from subject by formulation interaction variability (${\sigma}_D$) and within subject variability on reference drug (${\sigma}_{WR}$) and test drug (${\sigma}_{TR}$). To apply these methods, the switching variability (${\sigma}_0$) will have to be set by the regulatory authorities. The proposals of bioequivalence evaluation approach for the highly variable in Korea are presented for both of new drug and reevaluation drug.

• The KSFM Journal of Fluid Machinery
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• v.18 no.2
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• pp.22-28
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• 2015

The primary design goal of a compressor is focused on improving efficiency. Secondary objective is to widen the operating range of compressor. This paper presents a numerical and experimental investigation of the influence of the bleed slot on the operating range for the 1.2 MW class centrifugal compressor installed in a turbocharger. The main design parameters of the bleed slot casing are upstream slot position, inlet pipe slope, downstream slot position and width. The DOE(design of experiment) method was carried out to optimize the casing design. Numerical analyses were done by the commercial code ANSYS-CFX based on the three dimensional Reynolds-averaged Navier-Stokes equations. Results showed that efficiency and pressure ratio increased as the downstream slot position and width were smaller and the upstream position was located away from the impeller inlet. Experimental works were also done with and without the bleed slot casing. The simulation results were in good agreement with the test data. Enhancement of both the surge margin up to 26.5% and the pressure ratio with the optimized bleed slot design were achieved, compared with the surge margin of only 6.6% without the bleed slot casing.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1999.11a
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• pp.270-273
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• 1999

Y2k will be able to enormous disaster. The many make an effort to find a solution to problem of Y2k. Problem of Y2k must solution to as follow. First, problem of Y2k solution organization must constructed. Second, in step with each stage-the first, developing and complete stage, stage of Y2k solution must be constructed. Third, solution of Y2k must construct to hierarchy. hierarchy structure constructed form six stage to first stage, first stage is investigation resources, second stage is estimation influence, third stage is planing conversion, fourth stage is working conversion, fifte spot, sixth stage is diffusion on the spot.

• Journal of the Korean Geosynthetics Society
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• v.2 no.3
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• pp.11-18
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• 2003

The one of the most important concerns in the design of the final cover system is to restrict percolation of water into the waste body. To minimize entering the water, the final cover system has the barrier layer that consists of a single compacted clay liner(CCL) or a composite liner with high density polyethylene(HDPE) overlying CCL. The HDPE as well as CCL can be damaged by landfill settlements. Therefore, this study was conducted to assess the effects of HDPE induced by settlements in the final cover system after closure. The results of the three test that is field test, lysimeter test in laboratory, and prediction of settlement represent that the HDPE in the final cover system is not pretty much affected by settlements and stable on settlements.

• Journal of Astronomy and Space Sciences
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• v.19 no.4
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• pp.351-366
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• 2002

In this study, we developed low cost INS and (D)GPS integration for continuous attitude and position and utilized it for the determination of exterior orientation parameters of image sensors which are equipped in 4S-Van. During initial alignment process, the heading information was extracted from twin GPS and fine alignment with Kalman filter was performed for the determination of roll and pitch. Simulation and van test were performed for the performance analysis. Based on simulation result, roll and pitch error is around 0.01-0.03 degrees and yaw error around 0.1 degrees. Based on van test, position error in linear road is around 10 cm and curve around 1 m. Using direct georeferencing method, the image sensor's orientation and position information can be acquired directly from (D)GPS/INS integration. 4S-Van achieved 3D spatial data using (D)GPS/INS and image data can be applied to the spatial data integration and application such as contemporary digital map update, road facility management and Video GIS DB.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.10
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• pp.6014-6028
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• 2014

This study examined the levels of language anxiety and their causal factors in different English class environments. The findings show that the levels of language anxiety vary significantly in different types of class environments, indicating that both the class environments and individual characteristics are meaningful variables of language anxiety. The findings also show that unlike the levels of language anxiety, its causal factors are almost constant regardless of the class environment with communication apprehension being the most important factor. This study suggests that the English proficiency of students and professors needs to be considered when constructing specific class environments, in addition to promoting class environments favorable to students' active participation in class.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.3
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• pp.122-129
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• 2020

To conduct probabilistic seismic fragility analysis for nuclear power plants, it is very important to define the failure modes and criteria that can represent actual serious accidents. The seismic design criteria for piping systems, however, cannot fully reflect serious accidents because they are based on plastic collapse and cannot express leakage, which is the actual limit state. Therefore, it is necessary to clearly define the limit state for reliable probabilistic seismic fragility analysis. Therefore, in this study, the limit state of the SCH80 3-inch steel pipe elbow, the vulnerable part of piping systems, was defined as leakage, and the in-plane cyclic loading test was conducted. Moreover, an attempt was made to quantify the failure criteria for the steel pipe elbow using the damage index, which was based on the dissipated energy that used the moment-deformation angle relationship.

• Journal of Korean Society of Steel Construction
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• v.26 no.1
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• pp.11-20
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• 2014

The Concrete Capacity Design(CCD) method has been used in the design of anchor since 2001 and Korean design code specify that concrete breakout capacity of CIP anchor under seismic load shall be taken as 75% of static capacity. In this study, an experimental study was performed to evaluate the concrete breakout capacity of unreinforced CIP anchors under dynamic shear force. For the purpose, three static and dynamic shear-loading tests were conducted using 20mm diameter anchors, respectively. The edge distance of 120mm was considered in the tests. In the dynamic tests, 15 cycles pulsating load with 1Hz speed was applied and the magnitude of loading step was increased until concrete breakout failure occurs. From the tests, the concrete breakout capacity under dynamic shear loading showed nearly same capacity by static loading.

• Journal of the Society of Naval Architects of Korea
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• v.31 no.1
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• pp.14-21
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• 1994

The studios on the stability of damaged ships have been carried out continuously to prevent frequent damages or sinkings which cause large loss of life and fortunes. For dry cargo ships, continuing losses have resulted in new legislation of the probabilistic damage stability. IMO has developed requirements for the subdivison and damage stability of dry cargo ships based on probabilistic concepts. The calculation of the probabilistc damage stability is a complicated and iterative job hence development of computer programs is indispensable. In this research, programming of the probabilistic damage stability according to new requirements has been done and the results were compared with those carried out by the other foreign packages. New algorithm using a grid model in a transversal section was introduced to reduce efforts in preparing input data for damage scenarios and as a result, has brought significant improvement in efficiency and performance.