• Progress in Medical Physics
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• v.1 no.1
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• pp.31-42
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• 1990

The finding of long lived free radicals produced by ionizing radiation in organic crystals and the quantification of this effect by electron spin resonance(ESR) spactroscopy has proven excellent dosimetric applicability. The tissue equivalent alanine dosimeter also appear appropriate for radiation therapy level dosimetry. The dose measurement was performed in a Rando phantom using high energy photons as produced by high energy medical linear accelerator and cobalt-60 teletherapy unit. The absorbed dose range of the ESR/alanine dosimetry system could be extended down to 0.1 Gy. The response of the alanine dosimeters was determined for photons at different therapeutic dose levels from less than 0.1 Gy to 100 Gy and the depth dose measurements were carried out for photon energies of 1.25MeV, 6 and 10 MV with alanine dosimeters in Rando phantom. Comparisons between ESR/alanine in a Rando phantom and ion chamber in a water phantom were made performing depth dose measurements to examine the agreement of both methods under field conditions.

• Progress in Medical Physics
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• v.27 no.1
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• pp.8-13
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• 2016

Dual energy cone-beam CT can distinguish two materials with different atomic compositions. The principle of dual energy cone-beam CT based on modulation layer is that higher energy spectrum can be acquired at blocked x-ray window. To evaluate the possibility of modulation layer based dual energy cone-beam CT, we analyzed x-ray spectrum for various thicknesses of modulation layers by Monte Carlo simulation. To compare with the results of simulation, the experiment was performed on prototype cone-beam CT for 50~100 kVp with CdTe XR-100T detector. As the result of comparing, the mean energy of energy spectrum for 80 kVp are well matched with that of simulation. The mean energy of energy spectrum for 80 and 120 kVp were increased as 1.67 and 1.52 times by 2.0 mm modulation layer, respectively. We realized that the virtual dual energy x-ray source can be generated by modulation layer.

• Investigative Magnetic Resonance Imaging
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• v.11 no.2
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• pp.127-132
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• 2007

Sinonasal neuroendocrine carcinoma is a rare disease, and reports focusing on the MR imaging findings of sinonasal neuroendocrine carcinoma are extremely rare. Threrefore we intend to report 2 cases of histologically confirmed neuroendocrine carcinoma. A 62-year-old man and a 74-year-old man are both presented with nasal bleeding. Computed tomography(CT) images of the 2 patients showed large, ill-defined masses in sinonasal cavities with adjacent bony destructions. MR images showed masses with isosignal intensity on Tl-weighted images and mixed iso- and high signal intensity on T2-weighted images. Post-contrast MR images showed heterogenous enhancement of masses with necrosis. Adjacent bony destructions were also noted on MR images. In both cases, peritumoral cystic lesions or mucoceles with high signal intensity on T1-weighted images were noted in sphenoid sinus. Both of the CT and MR imaging findings of the 2 patients were nonspecific which are usually seen in malignant tumor. But further study is needed for the significance of the peritumoral cystic areas adjacent the tumors.

• Journal of Sensor Science and Technology
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• v.4 no.4
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• pp.1-9
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• 1995

The ${\gamma}$-ray deposition spectra were calculated by Monte Calro method to obtain the scintillation characteristics of the ${\gamma}$-ray for BGO scintillation detector with the spherical shape of 1.25 cm radius. The code used in calculating the ${\gamma}$-ray deposition spectra was made for personal computer with qbasic language. Also the ${\gamma}$-ray energy spectra of $^{22}Na$, $^{137}Cs$ and $^{207}Bi$ were measured with the detector. The energy dependent resolution below 2000 keV for the detector was determined by estimating the standard deviation of the photopeak fitted with gaussian function, and $X^{2}$ fitting using Nardi's empirical formula. The measured spectra of $^{22}Na$ and $^{137}Cs$ were compared with the broadened spectra which were obtained by broadening the calculated ${\gamma}$-ray deposition spectra with the energy dependent resolution. The absolute efficiency and the intrinsic peak efficiency of the detector were obtained by calculating the ${\gamma}$-ray deposition spectrum with the code.

• Journal of radiological science and technology
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• v.31 no.1
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• pp.83-87
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• 2008

The purpose of this study is to get the correction factor to correct the measured values of the absolute absorbed dose proportional to the water equivalent depth. The measurement conditions in white polystyrene and water phantoms for 10MV X-ray beam are that the distance of source to center of ionization chamber is fixed at SAD 100 cm, the field sizes are $10{\times}10\;cm^2$, $20{\times}20\;cm^2$ and the depths are 2.3 cm, 5 cm, 10 cm, and 15 cm, respectively. The mean value of ionization was obtained by three times measurements in each field size and depths after delivering 100 MU from linear accelerator with output of 400 MU per min to the two phantoms. The correction factor and the percentage deviation in TPR were obtained below 0.97% and 0.53%, respectively. Therefore, we can get high accuracy by using the correction factor and the percentage deviation in TPR in measuring the absolute absorbed dose with the solid water equivalent phantom.

• Korean Journal of Environmental Agriculture
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• v.18 no.1
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• pp.41-47
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• 1999

To investigate the combined effect of gamma ray irradiation and NaCl treatment on Tradescantia somatic cell pink mutations, potted plants of Tradescantia 4430 were evenly sprayed with NaCl solution(170mM) 24 hours before irradiation(NaCl+${\gamma}$) and after irradiation(${\gamma}$+NaCl). Irradiation doses were 0.3, 0.5, 1.0 and 2.0 Gy of gamma-ray. The plants irradiated only with gamma radiation were used as control group(CT). Frequency of pink mutation increased linearly with irradiation close and the peak interval of elevated mutation frequencies appeared during 6∼12 days aver irradiation in all the experimental groups. The slope of dose-response curve in CT was 5.99($r^2$=0.99), while it were 4.55($r^2$=0.98) in NaCl+${\gamma}$ and 4.33($r^2$=0.99) in ${\gamma}$+NaCl. It seemed that pre- and post-treatment of NaCl had a protective effect it against radiation-induced cell damages since it decreased the slope value by more than 24%. It is suggested that protective effect on DNA damages can be invoked in irradiated stamen hair cells by NaCl treatment.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2016.05a
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• pp.100-102
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• 2016

Every crew are in great peril that they should put out a fire on board in person due to a property of ship isolated. Accordingly, it is essential to verify whether the fire-fighter's outfits and fire-fighting scenarios in accordance with present regulations are safe and effective actually. As a result of comparison between shore fire-fighter's outfits and fire-fighting scenarios and those on ship and statistics calculation of the place and frequency of the fire of actual ship, present limitations of fire suppression system and fire-fighter's outfits were proved. In addition, derive the distance to the place on ship that has highest frequency of fire occurrence from examining actual ship's drawings according to their description and size. Finally from experiments in more experimental groups by changing numbers of actual fire-fighters and environment and conduction of survey of a number of crew in active service on ship, the most effective fire-fighter's outfits system and fire-fighting scenarios will be derived.

• Progress in Medical Physics
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• v.15 no.2
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• pp.105-111
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• 2004

The parallel plate detector with dielectric film for dosimetry was designed to measure detection characteristic of 6 MV X-ray with medical linear accelerator. PTFE film was inserted into FEP films that are made by two one-side metal coated materials for ion source. The thicknesses of PTFE dielectric film was 100 ${\mu}{\textrm}{m}$ and the thickness of FEP dielectric film was 100 ${\mu}{\textrm}{m}$, respectively. This detector was fixed by two acrylic plate for physical hardness ad geometrical consistency. The geometrical condition for measurement with parallel-plate for detector was below; SSD=100 cm and the 5 cm depth between detector and phantom surface The major parameter of detector characteristics such as zero drift current, leakage current, charge response by applied voltage, reproducibility, linearity, TMR measurement, dose rate effect were measured. The zero drift currents are 8.3 pA and leakage currents are 10 pA. The charge response of applied voltage is showing linearity in 414 voltage. The measurement deviation of reproducibility in this detector is within 1% for dose and the linearity of applied dose shows in this detector. The TMR curves in phantom between this parallel plate detector and reference detector are matched within 3% deviation from maximum dose depth to 7.5 cm depth. It is considered that this dosimetric system is satisfactory for the purpose of the constancy check of the 6 MV x-ray from medical linear accelerator.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2004.11a
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• pp.153-156
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• 2004

Korea Food and Drug Administration(KFDA) has peformed the calibration of therapy level dosimeters for Co-60 radiation since 1979. The reference standard ionization chamber has been calibrated at BIPM in France. The uncertainty on the KFDA calibration coefficients is 0.9 %(k=2) for air kerma and absorbed dose to water. Since 1999 a national quality audit program for ensuring dosimetry accuracy in Korea radiotherapy centers has been performed by the KFDA. The uncertainty associated with the determination of the absorbed dose to water from the TLD readings for high energy x-ray is 1.6 %(k=1). The correction factors for energy, non-linearity dose response, and TLD holder are used in the dose determination. Agreement between the user stated dose and KFDA measured dose within ${\pm}$ 5 % is considered acceptable. KFDA TLD postal dose quality audit program was peformed for 71 beam qualities of 53 domestic radiotherapy centers in 2003. The results for quality assurance showed that 63 out of 71 beam qualifies (89 %) satisfied the acceptance limit. The second audit was carried out for the centers outside the limit and ail of them have been corrected.

• Progress in Medical Physics
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• v.23 no.3
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• pp.127-137
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• 2012

A conversing beam is firstly designed for radiosurgery by a neurosugern Lars Leksell in 1949 with orthogonal x-rays tube moving through horizontal moving arc to focusing the beam at target center. After 2 decades he composits 201 source of the Co-60 for gamma knife which beams focused at locus. Sveral linac-based stereotactic radiosurgery using the circular collimated beam which size range for 0.4~4.0 cm in a diameter by non-coplanar multiarc have been developed over the decades. The irregular lesions can be treated by superimposing with several spherical shots of radiation over the tumour volume. Linac based techniques include the use of between 4 and 11 non-co-planar arcs and a dynamic rotation technique and use photon beam energies in the range of 6~10 MV. Reviews of the characteristics of several treatment techniques can be found in the literature (Podgorsak 1989, Schell 1991). More in recent, static conformal beams defined by custom shaped collimators or a mini- or micro-multileaf collimator (mMLC) have been used in SRS. Finally, in the last few years, intensity-modulated mMLC SRS has also been introduced. Today, many commercial and in-house SRS programs have also introduced non-invasive immobilization systems include the cyberknife and tomotherapy and proton beam. This document will be compared the characteristics of dose distribution of radiosurgery as introduced gamma knife, BrainLab include photon knife in-house SRS program and cyberknife in currently wide used for a cranial SRS.