• Title/Summary/Keyword: 생체적합도

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Current status on global sweetpotato cultivation and its prior tasks of mass production (세계 고구마 재배현황 및 대량생산의 선결과제)

  • Kim, Ho Soo;Lee, Chan-Ju;Kim, So-Eun;Ji, Chang Yoon;Kim, Sung-Tai;Kim, Jin-Seog;Kim, Sangyong;Kwak, Sang-Soo
    • Journal of Plant Biotechnology
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    • v.45 no.3
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    • pp.190-195
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    • 2018
  • Sweetpotato [Ipomoea batatas (L.) Lam] represents an attractive starch crop that can be used to facilitate solving global food and environmental problems in the $21^{st}$ century. It can be used as industrial bioreactors to produce various high value-added materials, including bio-ethanol, functional feed, antioxidants, as well as food resources. The non-profit Center for Science in the Public Interest (CSPI) announced sweetpotato as one of the ten 'super foods' for better health, since it contains high levels of low molecular weight antioxidants such as vitamin-C, vitamin-E and carotenoids, as well as dietary fiber and potassium. The United States Department of Agriculture (USDA) also reported that sweetpotato is the best bioenergy crop among starch crops on marginal lands, that does not affect food security. The Food and Agriculture Organization (FAO) estimated that world population in 2050 will be 9.7 billion, and require approximately 1.7 times more food than today. In this respect, sweetpotato will be a solution to solving problems such as food, energy, health, and environment facing the globe in the $21^{st}$ century. In this paper, the current status of resources, and cultivation of sweetpotato in the world was first described. Development of a new northern route of the sweetpotato and its prior tasks of large scale cultivation of sweetpotato, were also described in terms of global food security, and production of high-value added biomaterials.

Study on Strawberry 'Maehyang' Qualities Packed with MA film of Different Oxygen Transmission Rate during Simulated Export Distribution Conditions (산소투과도를 달리한 MA 필름으로 포장한 딸기 '매향'의 모의 수출 조건에서 품질 고찰)

  • Yoon, Hyuk Sung;Choi, In-Lee;Han, Su Jung;Kim, Ju Young;Choi, Ga Eun;Yoon, Jae Su;Kang, Ho-Min
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.23 no.2
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    • pp.83-87
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    • 2017
  • This study was conducted to determine types of oxygen transmission rate (OTR) films suitable for modified atmosphere (MA) storage treatment of strawberries (cv. 'Maehyang') for export and examination related changes in quality of strawberries during simulated shipping distribution conditions ($2^{\circ}C$ for $10days{\sim}8^{\circ}C$ for 11 days). Strawberries were packed by 1,300, 10,000, 20,000, and $30,000cc/m^2{\cdot}day{\cdot}atm$ OTR films for MA storage treatment and perforated film as the control for MAP. Fresh weight loss rate was less than 0.5% in OTR films except for the perforated film. Carbon dioxide and oxygen content in packages prevailed in permissible range for strawberries under recommended CA/MA conditions (i.e., $CO_2$: 15~20%, $O_2$: 5~10%) at 10,000 cc, 20,000 cc, and 30,000 cc OTR films. Ethylene content in OTR films did not reveal significant differences during storage. The 1,300 cc OTR film revealed highest off-flavor and lowest fungal incidence rate by sensory evaluation. The firmness, soluble solids, and visual quality were preserved the highest at 10,000 cc OTR film. In conclusion, 10,000 cc OTR film preserved the highest quality and extended shelf-life by 13 days if compared with conventional distribution conditions.

Discriminant Analysis of Human's Implicit Intent based on Eyeball Movement (안구운동 기반의 사용자 묵시적 의도 판별 분석 모델)

  • Jang, Young-Min;Mallipeddi, Rammohan;Kim, Cheol-Su;Lee, Minho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.6
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    • pp.212-220
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    • 2013
  • Recently, there has been tremendous increase in human-computer/machine interaction system, where the goal is to provide with an appropriate service to the user at the right time with minimal human inputs for human augmented cognition system. To develop an efficient human augmented cognition system based on human computer/machine interaction, it is important to interpret the user's implicit intention, which is vague, in addition to the explicit intention. According to cognitive visual-motor theory, human eye movements and pupillary responses are rich sources of information about human intention and behavior. In this paper, we propose a novel approach for the identification of human implicit visual search intention based on eye movement pattern and pupillary analysis such as pupil size, gradient of pupil size variation, fixation length/count for the area of interest. The proposed model identifies the human's implicit intention into three types such as navigational intent generation, informational intent generation, and informational intent disappearance. Navigational intent refers to the search to find something interesting in an input scene with no specific instructions, while informational intent refers to the search to find a particular target object at a specific location in the input scene. In the present study, based on the human eye movement pattern and pupillary analysis, we used a hierarchical support vector machine which can detect the transitions between the different implicit intents - navigational intent generation to informational intent generation and informational intent disappearance.

Studies on the Graft Polymerization of Polyethyleneglycol Monomethacrylate onto Chitosan and Drug(Vitamin B12) Permeation Behavior (키토산과 폴리에틸렌글리콜 모노메타크릴레이트의 그라프트중합과 약물(Vitamin B12)방출에 관한 연구)

  • Chung, Joo-Eun;Chung, Byung-Ok;Chang, Byung-Kwon;Choi, Kyu-Suk
    • Applied Chemistry for Engineering
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    • v.5 no.3
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    • pp.524-536
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    • 1994
  • Chitosan is known to be a good biocompatible natural polymer. Polyethyleneglycol monomethacrylates(PEGM) were grafted onto chitosan and their reaction conditions and properties of the graft polymers obtained were estimated. Using ceric ammonium nitrate(CAN) as the initiator, the optimum condition for graft polymerization was determined amount of the initiator and monomer concentrations and reaction time. Grafting yields such as total conversion, the percentage of grafting and the efficiency of grafting were calculated and examined the optimum reaction condition for high grafting yields. The percentage of grafting and total conversion were maximum at condition that the concentration of initiator was $4{\sim}5{\times}10^{-3}M$, the concentration of monomer was 0.5~0.6M, the reaction time was 2~3 hours and the reaction temperature was about $40^{\circ}C$. Thermal characteristics, solubility for chitosan solvents and inherent viscosity of synthesized graft copolymers were investigated. In high initiator concentration, characteristics of chitosan were greatly diminshed. In case of inherent viscosities, chitosan-g-PE-90 was 2.81 dl/g, chitosan-g-PE-200, 3.01dl/g and chitosan-g-PE-350, 4.93dl/g. And a tendency of viscosity increase depending on the length of ethylene oxide residue was confirmed. Degree of swelling, tensile strength, elongation of membrane prepared from graft copolymers were determined. Properties of graft copolymers were affected by percentage of grafting and length of ethylene oxides residue in polyethylene glycol monomethacrylates. Tensile strength, elongation and degree of swelling of graft copolymers were remarkably improved than chitosan. As percentage of grafting increased, the amount of drug permeation was also increased.

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Relative Evaluation for Biocompatibility of Pure Titanium and Titanium Alloys using Histological and Enzymatic Methods (조직학과 효소활성 방법을 이용한 순 타이타늄과 타이타늄 합금의 상대적인 생체적합성 평가)

  • Yeom, Dong-Sun;Kim, Byung-Il;Lee, Yu-Mi;Lee, Eun-Jung;Yee, Sung-Tae;Seong, Chi-Nam;Seo, Kwon-Il;Cho, Hyun-Wook
    • Toxicological Research
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    • v.23 no.4
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    • pp.331-339
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    • 2007
  • Titanium or titanium alloy is a widely used implant material according to its certified biocompatibility, sufficient strength and ready availability. The purpose of this study was to evaluate the relative biocompatibility of titanium and titanium alloy specimens (Ti-29Nb-13Ta, TiNb and Ti-6Al-4V, Ti64) using in vivo and in vitro methods. For in vivo experiment, the specimens were implanted in the abdominal subcutaneous region of female mice for 2 and 4 weeks. The reaction of connective tissue to specimens was evaluated histologically. The specimens were encapsulated by fibrous connective tissue consisting of fibroblast, fibrocyte and other cells including neutrophil, macrophage, giant multinucleated cell and unidentified cells. Some newly formed blood vessels were located in the fibrous capsule surrounding the implant. Cell types and the thickness of fibrous capsules were examined quantitatively. Most of cell types located in the fibrous capsule were fibroblasts and fibrocytes. The average thickness of fibrous capsules for the TiNb specimens was much thinner than that of the titanium alloy, Ti64. The thickness of the fibrous capsule around all titanium specimens decreased at 4 weeks compared to 2 weeks post-implantation. The biocompatibility of titanium and titanium alloy specimens were also investigated in in vitro method using alkaline phosphatase from MG-63 cells. Alkaline phosphatase activity of the TiNb specimen showed higher activity than the titanium alloy, Ti64. In conclusion, the TiNb alloy with thin capsule thickness in vivo and high alkaline phosphatase activity in vitro will be of considerable use in biomedical applications.

The Biocompatibility Of Cultured Bone Marrow Cells And Gingival Fibroblasts On The Titanium Surfaces (티타늄 배양에 대한 배양골수와 치은 섬유아세포의 생체적합성)

  • Oh, Choong-Young;Park, Joon-Bong;Kwon, Young-Hyuk;Lee, Man-Sup
    • Journal of Periodontal and Implant Science
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    • v.26 no.1
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    • pp.143-160
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    • 1996
  • The purpose of this study was to evaluate the response in aspect of attachment and growth rate of osteoblasts and growth rate of osteoblasts and human gingival fibroblasts to the commercially pure titanium(CP titanium)and titanium alloy(Ti-6AI-4V) that are used widely as implant materials, and to obtain the basic information to ideal implant materials. In the studly, commercially pure titanium in first test group, titanium alloy(Ti-6AI-4V) in second test group, cobalt-chrome-molybdenum alloy(Co-Cr-Mo alloy) in positive control group, and tissue culture polystyrene plate in negative control group were used. The results of this study were as follows. 1. Bone marrow cells cultured on CP titanium and Ti-6Al-4V showed significantly greater attachment and growth rate(p(0.05) compared to Co-Cr-Mo alloy in each time. 2. There were no significant differences(p>0.05) in attachment and growth rate of bone marrow cells cultured on CP titanium and Ti-6AI-4V or tissue culture plate. 3. Most bone marrow cells cultured on CP titanium, Ti-6Al-4V and tissue culture plate were attached well to each substratum in first 2days, and then, grew at higher growth rate. On the other hand, some cells cultured on Co-Cr-Mo alloy failed to attach in first 2 days, and then, attached cells grew at lower growth rate than other groups. 4. Attachment and growth rates of gingival fibroblasts cultured on CP titanium and Ti-6Al-4V showed no significant differences(p>0.05) compared to Co-Cr-Mo alloy in 2 days, but significantly greater increase(p<0.05) in 5 and 9 days. 5. There were no significantly differences(p>0.05) between growth rates on gingival fibroblasts cultured on CP titanium, Ti-6Al-4V and tissue culture plate in 2 and 5days, but a significant lower growth rate(p<0.05) on CP titanium and Ti-6Al-4V versus tissue culture plate. 6. Some gingival fibroblasts cultured on all specimen groups failed to attach, but attached cells grew well, especially on CP titanium, Ti-GAl-4V and tissue culture plate. 7. There were no significant differences(P>0.05) between growth rates of both bone marrow cells and gingival fibroblasts cultured on CP titanium and Ti-6AI-4V. As a result of this study, both commercially pure titanium and Ti-6AI-4V showed excellent biocompatibility and there was no significant difference in the cellular response to the both metals. Bone marrow cells cultured on each substratum showed significantly greater growth rate and responded sensitively to cytotoxic effects of metal surfaces compared to gingival fibroblasts. Considering cell response to the substrate, it was likely that the composition itself of titanium metals have no significant effect on the biocompatibility. Further study need to be done to evaluate the influence of surface characteristics on cellular responses.

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The effect of denture adhesives on the retention of complete denture (의치 접착제가 총의치의 유지력에 미치는 영향에 관한 연구)

  • Yoon, Yu-Mi;Choi, Yu-Sung;Lee, Joon-Seok
    • The Journal of Korean Academy of Prosthodontics
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    • v.48 no.2
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    • pp.87-93
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    • 2010
  • Purpose: The purpose of this study was to compare the retention of the two denture adhesives with a silicone edentulous model and a resin denture base in vitro study. Material and methods: The experimental groups were used two denture adhesives and classified into 5 subgroups each. Subgroups were divided by the number of times the saliva sprayed. The control group was used synthetic saliva only. Dislodging tensile strengths were applied to the resin denture base using Instron in 3 directions ; vertical, lateral, and anterior-posterior. Results: The retention of two denture adhesives was increased significantly than saliva alone (P <.05). In each denture adhesives, the retention of saliva sprayed first was decreased than denture adhesive alone, but it didn't have significant differences. Whenever saliva sprayed repeated, the retention was decreased significantly than saliva sprayed first (P <.05). In each denture adhesives, vertical retentive force was highest than lateral and anterior-posterior retentive forces, and anterior-posterior retentive force was higher than lateral retentive force. This results were significantly different (P < .05). Significant differences of the retentive ability among two denture adhesives were not observed. Conclusion: From the results, use of the denture adhesives resulted in improved retentive ability of denture. Especially retentive force was highest in vertical direction.

Full-mouth rehabilitation with pressed ceramic technique using provisional restorations (Pressed ceramic technique을 이용하여 제작되는 완전 도재관 완전 구강 회복 증례)

  • Roh, Hyun-Sik;Woo, Yi-Hyung;Pae, Ahran
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.1
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    • pp.47-51
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    • 2013
  • With the introduction of dental implants, restoration of missing teeth with conventional fixed or removable partial dentures is being replaced with implants. Especially, with young patients, not only longevity but also esthetic factors need to be considered. Implant restorations provide long-term success functionally but, esthetic complications such as, marginal exposure due to gingival recession, loss of the papilla and dark color of metal abutments may occur. Recently, zirconia restorations with CAD/CAM technology provide functional, biocompatible and esthetic restorations possible. All-ceramic restorations using the pressed ceramic technique show better fracture toughness values than those of the conventional porcelain veneering technique. Pressed ceramic technique creates the veneer design in wax and the lost wax technique is used to create the restoration. The final contour of the restoration may be controlled during wax-up. A 22-year old female patient was restored with dental implants and zirconia restorations using the pressed ceramic technique presenting short-term but optimistic prognosis.

Effects of Mineral Trioxide Aggregate on the Proliferation and Differentiation of Human Dental Pulp Stromal Cells from Permanent and Deciduous Teeth (Mineral trioxide aggregate가 유치 및 영구치의 치수기질세포 증식 및 분화에 미치는 영향)

  • Kim, Seunghye;Jeon, Mijeong;Shin, Dong Min;Lee, Jae Ho;Song, Je Seon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.40 no.3
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    • pp.185-193
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    • 2013
  • Mineral trioxide aggregate (MTA) has recently been used as a pulpotomy medicament for primary molars. The aim of this study was to evaluate and compare the proliferation and differentiation potential of dental pulp stromal cells of permanent teeth and deciduous teeth cultured on MTA-coated surface. Human dental pulp stromal cells were obtained from human permanent premolars and deciduous teeth and cultured on MTA-coated culture plates. The cells were subjected to proliferation assay and cell cycle analysis. Their differentiation potential was evaluated by analysing changes in the mRNA expressions of runt-related transcriptional factor 2 (Runx2) and alkaline phosphatase (ALP). Morphological changes of cells in direct contact with MTA were observed using scanning electron microscopy (SEM). The proliferation rates, distribution of cell cycles and mRNA expression patterns of Runx2 and ALP were similar in both types of pulpal cells. SEM observations revealed that both types changed into more dendrite-like cells. On the surface of MTA, human dental pulp stromal cells from deciduous and permanent teeth were able to both proliferate and differentiate into cells that induce mineralization. MTA is suitable as a biocompatible pulpotomy medicament for primary teeth.

Mechanical strength of Zirconia Abutment in Implant Restoration (지르코니아 임플란트 지대주의 기계적 강도에 관한 연구)

  • Shin, Sung-ae;Kim, Chang-Seop;Cho, Wook;Jeong, Chang-Mo;Jeon, Young-Chan;Yun, Ji-Hoon
    • Journal of Dental Rehabilitation and Applied Science
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    • v.25 no.4
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    • pp.349-360
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    • 2009
  • Purpose: As the esthetic demands of dental implant patients are increased, the demands of zirconia as implant abutment material are also increased. It has non-metalic color, good biocompatibility, high strength and high toughness. Even thought the advatage of zirconia abutment, there are a few studies about mechanical properties of zirconia abutment. This study evaluated the mecanical strength with compressive bending strength and endurance limit of implant-zirconia abutment assembly. Materials and Methods: Static and cyclic loading of implant-Zirconia abutment assembly were simulated under worst case condition according to ISO. Test groups were implants of external butt joint with straight regular diameter and angled regular diameter zirconia abutment, implant of external butt joint with narrow straight diameter zirconia abutment and implant of internal conical joint with straight narrow diameter zirconia abutment. All test group were evaluated the mecanical strength with compressive bending strength and endurance limit. After fatique testing, fracture surface were examined by SEM. Results: The compressive bending strengths exceed 927N. Regular diameter zirconia abutment were stronger than narrow diameter zirconia abutment(P<.05). The endurance limits ranged from 503N to 868N. Conclusion: Within the limitation of this study, zirconia implant abutment exceeded the estabilished values for maximum incisal biting forces reported in the literature.