• Title/Summary/Keyword: 생체적합도

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Blood Compatibility of Hollow Fiber Membranes Treated by Plasma Polymerization (플라즈마 중합 처리된 중공사 막의 혈액 적합성)

  • Lee, Sam-Cheol;Kwon, O-Sung
    • Membrane Journal
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    • v.15 no.3
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    • pp.233-240
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    • 2005
  • Surface modification of polypropylene hollow fiber membranes was performed in order to develop blood-compatibility biomaterials for use in the blood contacting surfaces and oxygenation membranes of a lung assist device (LAD), important medical device even more useful. Blood compatibility of materials was determined by using anticoagulation blood and evaluating formation of blood clots on their surfaces as well as activation of plasma coagulation cascade, platelet adhesion, and aggregation. It was verified that the number of platelets on the silicone coated fibers was significantly lower than that on untreated fiber membrane, indicating improved blood compatibility. It was also found that the polypropylene hollow fiber membranes using plasma treatment exhibited suppression of complement activation in blood compatibility test.

Calculation and Applicability of Rotifers Biomass (Polyarthra spp.) based on Length-Weight Relationship and Spatial Distribution of Body Length (윤충류 생체량 계산과 적용에 관한 고찰 및 제언: Polyarthra의 체장 분포를 이용한 길이-무게 관계식 및 생체량 비교 분석)

  • Oh, Hye-Ji;Seo, Dong-Hwan;Choi, Moonjung;Jeong, Hyun-Gi;Kim, Hyun-Woo;Oh, Jong Min;Chang, Kwang-Hyeon
    • Korean Journal of Ecology and Environment
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    • v.51 no.3
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    • pp.205-211
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    • 2018
  • In this study, we estimated the applicability of length-weight relationship-based biomass calculations by comparison of body length of genus Polyarthra collected from different habitats. Through the comparison, we also tested availability of representative species-specific biomass value of Polyarthra which is often used without length measurement. Polyarthra samples were collected from rivers (Han River and Nakdong River) and reservoir (Paldang Reservoir), and the body length was measured for statistical comparison among habitats and biomass calculations using different equations suggested previously. According to the results, the body length of Polyarthra spp. was significantly different among sampling sites, and the necessity of body length measurement for rotifer species in each situation has been suggested rather than using the representative biomass values which is fixed without considering time and space. Comparison of suggested biomass calculations based on our measured Polyarthra body length, the equation suggested by McCauley showed more reasonable range of biomass values than that suggested by EPA. In addition, in order to calculate more accurate biomass, it is necessary to measure the body length of rotifers, at least more than 44 individuals to reduce error probability to less than 5% with 99% probability. However, since direct measurement of rotifers biomass is limited, it is considered that further analyses are required for more precise application of rotifer biomass of which has high variability due to complex morphologies and species-specific cyclomorphosis often induced by biotic and abiotic factors in the habitats.

Study of Biomass Estimation Methods for the Freshwater Cladoceran Species, Simocephalus serrulatus (Koch, 1841) (담수산 지각류 Simocephalus serrulatus (Koch, 1841) 생체량 산정 방법 연구)

  • Hye-Ji Oh;Geun-Hyeok Hong;Yerim Choi;Kwang-Hyeon Chang
    • Korean Journal of Ecology and Environment
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    • v.56 no.2
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    • pp.161-171
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    • 2023
  • The medium-large cladoceran species Simocephalus spp. predominantly occur in habitats with developed aquatic vegetation. Accordingly, due to Simocephalus' high contribution to zooplankton community biomass in the lake's littoral zone and wetland habitats, estimating their biomass is important to understand the matter cycling based on biological interactions within the aquatic food web. In this study, we reviewed the length-weight regression equations used previously to estimate Simocephalus biomass, directly measured S. serrulatus' body specification (length, width and area) and their biomass(dry weight) using instruments such as a microscopic digital camera and a microscale, and performed regression analysis between each other. When S. serrulatus biomass was estimated using the equation (Kawabata and Urabe, 1998) presented in 『Biomonitoring Survey and Assessment Manual』, Korea, errors between estimates and measures were relatively large compared to the S. serrulatus species-specific biomass estimate equation developed by Lemke and Benke (2003). In addition, both equations showed not only increasing trends in error (estimate-measure) with increasing S. serrulatus' body length, but also in error variance among similar-sized individuals. The results of regression analysis with dry weight by body specifications indicated that the most appropriate equation for estimating the biomass of S. serrulatus was derived from the width-dry weight exponential regression equation (R2=0.9555). The review and development study of such species-specific biomass estimation equations for zooplankton can be used as a tool to understand their role and function in aquatic ecosystem food webs.

The Promotion of Cell Attachment and Proliferation on Silk Fibroin (실크 생체막에 대한 세포 부착 및 세포 증식)

  • Jo, You-Young;Kweon, Hae-Yong;Lee, Kwang-Gill;Nam, Sung-Hee;Lee, Heui-Sam;Yeo, Joo-Hong
    • Journal of Applied Biological Chemistry
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    • v.54 no.3
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    • pp.166-170
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    • 2011
  • Silk fibroin, a natural protein produced by silkworm, is a good biomaterial which has biodegradability and biocompatibility. To ascertain the effects of silk fibroin on cell growth, silk fibroin films were prepared using silk fibroin aqueous solutions of various concentrations. We investigated the attachment, proliferation, morphology of the cells and the expression levels of genes related to cell attachment and growth on the silk fibroin films. When the cells were cultured on the 0.1 and 1% silk fibroin film, the cell adhesion ability was very excellent. Particularly, overall cell growth on the 1% silk fibroin film was definitely superior to the others. Also, expression levels of genes related cell growth were increased on the 0.1 and 1% silk fibroin film. These results suggest silk as a material for medical applications.

The Design of Feature Selection Classifier based on Physiological Signal for Emotion Detection (감성판별을 위한 생체신호기반 특징선택 분류기 설계)

  • Lee, JeeEun;Yoo, Sun K.
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.11
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    • pp.206-216
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    • 2013
  • The emotion plays a critical role in human's daily life including learning, action, decision and communication. In this paper, emotion discrimination classifier is designed to reduce system complexity through reduced selection of dominant features from biosignals. The photoplethysmography(PPG), skin temperature, skin conductance, fontal and parietal electroencephalography(EEG) signals were measured during 4 types of movie watching associated with the induction of neutral, sad, fear joy emotions. The genetic algorithm with support vector machine(SVM) based fitness function was designed to determine dominant features among 24 parameters extracted from measured biosignals. It shows maximum classification accuracy of 96.4%, which is 17% higher than that of SVM alone. The minimum error features selected are the mean and NN50 of heart rate variability from PPG signal, the mean of PPG induced pulse transit time, the mean of skin resistance, and ${\delta}$ and ${\beta}$ frequency band powers of parietal EEG. The combination of parietal EEG, PPG, and skin resistance is recommendable in high accuracy instrumentation, while the combinational use of PPG and skin conductance(79% accuracy) is affordable in simplified instrumentation.

Research on DNN Modeling using Feature Selection on Frequency Domain for Vital Reaction of Breeding Pig (모돈 생체 반응 신호의 주파수 영역 Feature selection을 통한 DNN 모델링 연구)

  • Cho, Jinho;Oh, Jong-woo;Lee, DongHoon
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2017.04a
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    • pp.166-166
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    • 2017
  • 모돈의 건강 상태를 정량 지수화 하기 위한 연구를 수행 중이다. 지제이상, 섭식 불량, 수면 패턴 등의 운동 특성 분석을 위하여 복수의 초음파 센서를 이용하였다. 시계열 계측 신호를 분석하여 정량 지수화를 수행하는 과정에서 주파수 도메인 분석을 시도하였다. 이 과정에서 주파수 도메인의 분해능에 따른 편차 극복을 위한 비선형 모델링을 수행하였다. 또한 인접한 시계열 데이터 구간 간의 상관성 분석이 가능하면 대용량 데이터의 실시간 처리로 인한 지연 시간 극복 및 기대되는 예후에 대한 조기 진단이 가능할 것이다. 본 연구에서는 구글에서 제공하는 Tensorflow와 NVIDIA에서 제공하는 CUDA 엔진을 동시 적용한 심층 학습 시스템을 이용하였다. 전 처리를 위하여 주파수 분해능 (2분, 3분, 5분, 7분, 11분, 13분, 17분, 19분)에 따른 데이터 집합을 1단계로 두고, 상위 10 순위 안에 드는 파워 스펙트럼 밀도의 크기를 2단계로 하여, 총 2~10개의 입력 노드를 순차적으로 선정하였고, 동일한 방식으로 인접한 시계열의 파워 스펙터럼 밀도를 순위를 변화시켜 지정하였다. 대표적인 심층학습 모델인 Softmax regression with a multilayer convolutional network를 이용하여 Recursive feature selection 경우의 수를 $8{\times}9{\times}9$로 총 648 가지 선정하고, Epoch는 10,000회로 지정하였다. Calibration 모델링의 경우 Cost function이 10% 이하인 경우 해당 경우의 학습을 중단하였으며, 모델 간 상호 교차 검증을 수행하기 위하여 $_8C_2{\times}_8C_2{\times}_8C_2$ 경우의 수에 대한 Verification test를 수행하였다. Calibration 과정 상 모든 경우에 대하여 10% 이하의 Cost function 값을 보였으나, 검증 테스트 과정에서 모든 경우에 대하여 $r^2$ < 0.5 인 결정 계수 값이 나타났다. 단적으로 심층학습 모델의 과도한 적합(Over fitting) 방식의 한계를 보인 것이라 판단할 수 있다. 적합한 Feature selection 및 심층 학습 모델에 대한 지속적이고 추가적인 고려를 통해 과도적합을 해소함과 동시에 실효적이고 활용 가능한 Classification을 위한 입, 출력 노드 단의 전후 Indexing, Quantization에 대한 고려가 필요할 것이다. 이를 통해 모돈 생체 정보 정량화를 위한 지능형 현장 진단 기술 연구를 지속할 것이다.

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Optimal Cultural Conditions for Prothallus Propagation and Sporophyte Formation of Dryopteris hangchowensis Ching (각시톱시네고사리의 전엽체 증식 및 포자체 형성을 위한 최적의 배양조건)

  • Park, Kyung Tae;Jang, Bo Kook;Lee, Ki Cheol;Lee, Cheol Hee
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2018.10a
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    • pp.71-71
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    • 2018
  • 본 연구는 각시톱시네고사리(Dryopteris hangchowensis Ching)의 전엽체 증식 및 포자체 형성을 위한 번식방법을 구명하고자 수행되었다. 각시톱지네고사리의 식물체를 무가온 온실에 재배하면서 포자를 채취하였으며, 수집된 포자는 기내에서 발아시켜 전엽체를 획득한 다음 계대배양하면서 실험의 재료로 사용하였다. 전엽체 대량증식을 위하여 1/4, 1/2, 1배로 조절한 MS배지와 Knop배지를 조성하였다. 이후 전엽체 300mg을 균일하게 다져 조성된 배지에 8주간 배양하였다. 연구의 결과, 전엽체의 생체중은 1/2MS와 1/4MS에서 3.4g으로 가장 많이 증가하였다. 현미경 관찰의 결과, 두 배지 모두 정상적인 전엽체의 형태로 발달하였으며, 생육도 양호하였다. 포자체 형성을 위한 적정 배양토의 혼합조건을 확인하고자 원예상토, 피트모스, 펄라이트 및 마사토의 혼합비율을 5종류로 달리하여 조성하였다. 준비된 배양토를 사각분($7.5{\times}7.5{\times}7.5cm$)에 충진 후 기내 배양한 전엽체 1g과 증류수를 함께 10초간 분쇄하여 토양표면에 균일하게 분주한 다음 12주간 재배하였다. 연구의 결과, 원예상토, 피트모스, 펄라이트를 1:1:1(v:v:v) 비율로 혼합한 토양에서 포트 당 223.7개로 가장 많은 포자체가 형성되었다. 또한 형성된 포자체의 생육을 조사한 결과, 상기 토양에서 생체중, 엽수, 엽장, 엽폭, 근수, 근장 및 SPAD value 등의 생육수치가 우수하였다. 따라서 각시톱시네고사리의 전엽체 증식에 적합한 배지는 경제성과 생육수준을 고려하여 1/4MS 배지가 적합하며, 포자체 대량생산을 위해서는 원예상토, 피트모스, 펄라이트를 1:1:1(v:v:v)로 혼합한 토양이 적합하다고 판단되었다.

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Evaluating Impressions of Robots According to the Robot's Embodiment Level and Response Speed (로봇의 외형 구체화 정도 및 반응속도에 따른 로봇 인상 평가)

  • Kang, Dahyun;Kwak, Sonya S.
    • Design Convergence Study
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    • v.16 no.6
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    • pp.153-167
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    • 2017
  • Nowadays, as many robots are developed for desktop, users interact with the robots based on speech. However, due to technical limitations related to speech-based interaction, an alternative is needed. We designed this research to design a robot that interacts with the user by using unconditional reflection of biological signals. In order to apply bio-signals to robots more effectively, we evaluated the robots' overall service evaluation, perceived intelligence, appropriateness, trustworthy, and sociability according to the degree of the robot's embodiment level and the response speed of the robot. The result showed that in terms of intelligence and appropriateness, 3D robot with higher embodiment level was more positively evaluated than 2D robot with lower embodiment level. Also, the robot with faster response rate was evaluated more favorably in overall service evaluation, intelligence, appropriateness, trustworthy, and sociability than the robot with slower response rate. In addition, in service evaluation, trustworthy, and sociability, there were interaction effects according to the robot's embodiment level and the response speed.

Active Spinning Training System using Complex Physiological Signals (복합 생체신호를 이용한 능동형 스피닝 트레이닝 시스템)

  • Kim, Cheol-Min;Kang, Gyeong-Heon;Kim, Eun-Seok
    • The Journal of the Korea Contents Association
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    • v.15 no.7
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    • pp.591-600
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    • 2015
  • Recently high interest in health and fitness has led to vibrant researches for the active fitness system to learn and enjoy the exercise program for oneself. In this paper, we design and implement the active spinning training system which enables user to have self-learning and experience of customized spinning training program by the biometric and movement information acquired from user's physiological signals. The proposed system provides the appropriate difficulty of spinning program which reflects the concordance rate of spinning dance gestures and the amount of exercising by analyzing the physical status of participant from his brain and pulse waves and recognizing the skeletal movement in real time. For the higher exercise effect, the system offers a virtual personal trainer to show the correct poses and controls the level of difficulty depending on the concordance rate of participant's motions. The experiment with various participants through the proposed system shows that it is able to help users in getting the available exercise effect in comparatively short time.

Identifying Optimal AMG Concentration for Promoting Growth of Lactuca sativa L. cv. Fidel at Plant Factory System (식물공장내 상추 '피델'의 생육 촉진을 위한 최적 AMG 농도 구명)

  • Song, Tae Eui;Kim, Bo Mi;Park, Sung Jik;Moon, Jun Kwan;Kim, In Soo;Goo, Ja Jun;Lee, Chang Hee
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2018.04a
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    • pp.55-55
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    • 2018
  • 본 연구는 상추 '피델'을 이용한 완전제어형 식물공장에서의 재배를 하기 위해 기존의 배양액에 생육 촉진용 AMG의 농도를 구명하고 그에 맞는 매뉴얼을 확립하기 위해 실시하였다. 실험은 기존 배양액에 AMG(고활성 칼슘용액+복합 활성 미네랄)를 추가하였으며 '피델'의 생육에 적합한 AMG의 농도는 0, 0.05, 0.1, 0.2%를 양액에 추가하여 5반복 4처리로 진행하였다. 생육 조사 항목은 초폭, 초장, 엽장, 엽폭, 엽록소, 생체중을 조사하였다. '피델'의 생장에서 초폭, 엽폭, 엽장은 3주차부터 생장량이 급증하였으며 AMG 4처리구 5주차 조사에서는 초폭 평균 335g, 357g, 369g, 381g을 나타냈으며 엽폭은 평균 168g, 191g, 202g, 208g, 엽장 평균 129g, 134g, 144g, 144g으로 조사되었다. AMG 농도 0.1~0.2%는 통계적으로 생장 촉진 효과가 나타났으나 유의차가 크지 않아 0.1% AMG가 적정한 것으로 판단되었다. 엽록소 함량의 경우 정식 2주차 이후서부터는 SPAD 평균 29~32로 기록되어 엽록소함량은 크게 변화하지 않았다. 또한 엽수의 증가폭에 비해 생체중의 증가폭이 컸으며 생체중의 경우 정식 3주부터 5주 사이에 생체중이 5배 이상 급증하는 생장 패턴을 나타내었다. 5주차 생체중에서는 0% AMG의 경우 평균 82g, 0.05% AMG는 평균 85g, 0.1% AMG는 평균 115g, 그리고 0.2% AMG는 평균 114g으로 조사되었다. 따라서 0.1~0.2% AMG에서는 차이가 없게 나타남에 따라 생장촉진을 위해서는 0.1% AMG를 추가하는 것이 적정하다고 판단되었다.

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