• Journal of The Korean Society of Grassland and Forage Science
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• v.38 no.4
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• pp.298-309
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• 2018

This study examined the multi-functionality of an eco-pastoral system in alpine grassland and measured its economic value. The multi-functionality can be divided into three categories: direct-use value, indirect-use value, and heritage value. Direct-use value includes both extractive (forage and livestock production) and non-extractive (recreation and tourism) functions. Indirect-use value includes the functions of water conservation, soil erosion control, atmospheric control, landscape, livestock-manure management, and forest firebreaks. The heritage value includes the function of species diversity. The results showed that the annual value for 1 hectare of the eco-pastoral system in alpine grassland's direct use was estimated to be 21,090,874 Korean won; the indirect-use value was 15,562,203 won when the landscape in grassland system, and 16,018,224 won when the landscape comprised in silvopastoral system. The value of the species diversity in heritage terms ranged from 767,273 to 1,578,845 won, depending on whether it included any endangered species. The total value of multi-functionality of the eco-pastoral system in alpine grassland was estimated to be a minimum of 37,420,350 won/ha and a maximum of 38,687,942 won/ha. The results of this study can provide useful insights for the eco-pastoral system in alpine grassland policies in Republic of Korea.

• Journal of agriculture & life science
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• v.52 no.6
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• pp.1-12
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• 2018

This study was conducted to analyze the openness of erosion control dams situated near mountain stream. The ecological functions of erosion control dams analyzed by such openness for adequately protect and manage the diversity of species and to prevent disasters. The obtained results were as follows. When structurally modifying or changing non-permeable, gravity type dams with a passing rate of less than 1% into open-type dams, the passing rate increased by about 77 times more from 0.72% to 55.8%. Except for closed, gravity type erosion control dams that are constructed with a special purpose such as creating sand deposits and reservoirs, there is a need to construct and improve the dams into permeable type dams that can relatively satisfactorily perform various functions such as carrying soil and sand to the downstream region and create a ecological corridor upstream and downstream for fish and amphibians. The openness based on the blocking height of the erosion control dam varies depending upon the height of the base part and the depth of the substructural part. It must be designed based on the on-site conditions and the purpose of the construction. The functional types of erosion control dams based on the open form of the cross-section as follows: the fish traffic type, flood control type, reservoir type for forest fire control), non-permeability type for soil and rock blocking, net type for blocking the rock flow and the particle screen type.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.180-180
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• 2021

가로수는 「도로법」 제11조에 따른 도로(고속국도를 제외한다)와 보행자전용도로 및 자전거전용도로 등 대통령령으로 정하는 도로의 도로구역 안 또는 그 주변지역에 심는 수목을 말하며, 도시의 가로수는 기후조절효과 및 대기오염 정화효과 등을 가질 뿐 아니라 도심지 내에 녹색을 도입하고 도시경관을 구성하는 주요 요소이다. 전국 각 시도에서는 가로수 조성사업을 지속적으로 추진하고 있다. 하지만 몇몇 도시에서는 적절하지 않은 가로수 관리로 인해 가로수가 말라죽는 현상이 증가하고 있다. 이에 가로수 고사 현상을 감소시키기 위하여 토양수분과 토양온도를 측정하여 가로수 피해와 연관성을 조사할 필요성이 있다고 판단하였다. 본 연구는 춘천시에서 진행하였으며, 일반 가로수와 현재 가로수 고사로 문제가 되고 있는 3 모니터링 지점을 선정하고, 토양수분 센서를 5, 15, 40 cm 깊이에 설치하였다. 센서를 이용하여 토양수분과 지온, EC 모니터링을 실시하였다. 토양수분 모니터링 자료를 활용하여 토층별 토양수분 소비량 산정을 하고, 현장 토양시료를 채취하여 물리·화학적 특성을 분석하였다. 또한 가로수 증발산량 산정 및 토층별 토양수분 소비량과 소비패턴을 비교하였다. 본 연구 결과를 향후 RZWQM(Root Zone Water Quality Model) 모델의 기초자료 및 시나리오 구성에 활용될 수 있으며, 모니터링 및 모델링 결과를 활용하여 가로수 및 도시 표토 기능 위협 요인을 분석에 활용 될 수 있다.

• Journal of Life Science
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• v.20 no.2
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• pp.231-236
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• 2010

Antibiotics in veterinary medicine have been used to treat disease, promote growth rate and improve feed efficiency. However, alternative sources are needed because of of bacterial resistance to antibiotics and residues of antibiotics. The present study was carried out to evaluate the effect of CS682, a fermentation product of Korean soil bacteria, on safety, growth rate and feed efficiency, and to evaluate its value as an alternative for antibiotics used as a feed additive. Two dosages of CS682 (0.1% and 1%) were fed to chickens for 28 days. The results showed that, when compared to chickens in the control group, growth and feed efficiency was improved. Also, mortality, hematology, general clinical signs and necropsy were examined. Chickens in the treatment groups showed no adverse effects. A total of 72 weaning pigs were used to confirm the effects of CS682 at one dose level (0.1%) regarding feed efficiency. Supplementation with 0.1% CS682 also resulted in improved weight gain and feed efficiency ratio. Based on these results, CS682 may be effective in improving feed efficiency safely as a feed additive.

• Proceedings of the Korean Information Science Society Conference
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• 2003.10b
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• pp.832-834
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• 2003

단백질은 생명현상 유지에 필수적인 기능을 담당하며 이러한 기능이 단백질의 3차 구조에 의해 결정된다는 것이 밝혀짐으로써 단백질 3차 구조에 대한 연구가 더욱 활발히 진행되고 있다. 본 논문에서는 단백질의 3차 구조를 파악할 수 있는 Java3D 기반의 단백질 구조 뷰어인 KPDBViewer에 대하여 기술한다. 개발된 KPDBViewer는 3차원 이미지 상에서 단백질 내 아미노산들의 이벤트 처리를 지원함으로써 단백질내 아미노산의 정보를 보다 효과적으로 파악할 수 있다 또한, Java2D 기반의 단백질 뷰어는 다양한 구조 보기 기능이 부족하다. 이와 같은 기능을 제공함으로써 단백질 구조 정보를 보다 쉽게 이해하는데 도움을 줄 것으로 기대한다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.439-441
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• 2004

소프트웨어 시험은 소프트웨어 제품의 고 품질을 보장하기 위한 중요한 요소들 중의 하나이고, 특히 신뢰도가 원자력 발전소외 안전에 직결되는 디지털 기반의 원전 계측제어계통 소프트웨어는 고품질과 고신뢰도를 제공하여야 한다. 그러므로 원자력발전소에 사용되는 소프트웨어는 안전성과 신뢰성을 제공하기 위해 체계적인 시험을 통하여 설계의 정당성을 확인하고, 요건명세서나 설계사양서에 나타난 계통 및 구성요소의 기능과 요건들이 만족하게 실행됨을 확인하여야 한다. 규제기관에서도 소프트웨어의 안정성, 기능의 완전한 수행, 소프트웨어 자체가 계통의 기능을 저하 시키는지와 계통에게 예정되지 않은 기능을 수행하도록 영향을 주는지외 확인 등을 소프트웨어 시험을 통해 확인하도록 요구하고 있다. 이와 같이 원자력발전소에 사용되는 소프트웨어의 시험을 위해서는 보다 엄격하고 명확한 시험 프레임웍을 개발하고 적용키는 것이 필요하다. 본 논문에서는 소프트웨어 시험과 관련된 인허가 규제요건을 분석하고, 이에 따라 현재 설계를 진행중인 SMART MMIS 소프트웨어 시험에 적용될 소프트웨어 개발생명주기 시험활동, 시험 조직, 시험문서, 소프트웨어 등급별 시험방법 등 시험 프레임웍을 제시한다.

• Journal of Life Science
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• v.23 no.11
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• pp.1409-1414
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• 2013

Lymph node (LN) is the sites where mature lymphocytes become stimulated to respond to invading pathogens in the body. Lymphocytes screen the surfaces of pathogen-carrying antigen-presenting cells for cognate antigens, while moving along stromal structural back bone. Fibroblastic reticular cells (FRC) is stromal cell forming the 3 dimensional structure networks of the T cell rich zones in LN, and provide a guidance path for immigrating T lymphocytes. In these cooperative environments, the cell to cell bidirectional interactions between FRC and T cells in LN are therefore essential to the normal functioning of these tissues. Not only do FRCs physically construct LN architecture but they are essential for regulating T cell biology within these domains. FRC interact closely with T lymphocytes, is providing scaffolds, secreting soluble factors including cytokine in which FRCs influence T cell immune response. More recently, FRC have been found to induce peripheral T cell tolerance and regulate the extent to which newly activated T cells proliferate within LN. Thus, FRC-T cell crosstalk has important consequences for regulating immune cell function within LN. In addition, FRC have profound effects on innate immune response by secreting anti-microbial peptides and complement, etc in the inflammatory milieu. In summary, we propose a model in which FRC engage in a bidirectional touch to increase the T cell biological efficiency between FRC and T cells. This collaborative feedback loop may help to maintain tissue function during inflammation response.

• Journal of agriculture & life science
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• v.44 no.6
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• pp.121-132
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• 2010

Soybean farms in Changnyeong were selected for hazard analysis to establish the Good Agricultural Practices (GAP) model of soybean, and physical, chemical(heavy metal) and biological(sanitary indications, foodborne pathogens) hazard analysis for cultivation environment (soil, water) was carried out. First, bow which is able to be mixed in soil and water was confirmed as physical hazard. Levels (Cd:0.01~0.103, Cu:0.001~6.036, As:0.006~3.045, Hg:ND~0.041, Pb:0.003~3.952, $Cr^{+6}$:0.007~0.496, Zn:0.001~66.500, Ni:0.003~18.010) of heavy metals in soil and water were appropriate for GAP criteria. In biological hazard, APC and coliform in soil were detected at the levels of $6.0{\pm}0.3$ and $3.6{\pm}1.6$ log CFU/g, and levels of water were $3.5{\pm}0.7$ and $1.9{\pm}0.7$ log CFU/mL, while E. coli wasn't detected in all sample. However, coliform in water wasn't appropriate for criteria, and E. coli O157 was detected about 22% in some farms, so it needs ways to prevent contamination by human and animals excrements. In conclusion, it needs proper management to prevent cross-contamination of hazards although physical and chemical hazard level were appropriate for GAP criteria while biological hazard wasn't.

• Journal of Food Hygiene and Safety
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• v.36 no.4
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• pp.347-352
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• 2021

Yam (Dioscorea japonica) is widely utilized as food and a pharmaceutical ingredient as it contains a variety of valuable constituents. Allantoin is one of the bioactive components in yam that is used in pharmaceutical and cosmetic industry. This study was conducted to analyze and compare the allantoin content of yam flesh and peel by HPLC analytical method using an amino bonded-phase column to make up for the limitations of the previous HPLC analytical methods. The allantoin contents of yam flesh and peel were 3.09±0.025 and 3.91±0.11 mg/g (dry weight), respectively. The results of this study indicated that yam peel has higher allantoin content than yam flesh, and that the discarded yam peel could be used as a source for high value-added functional materials.

• Journal of Life Science
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• v.33 no.1
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• pp.64-72
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• 2023

Despite several advances in identification of cardiac transcription factors, there are still needs to find new bioactive molecules that promote cardiomyogenesis from stem cells to highly efficient myocardial differentiation. We analyzed Illumina expression microarray data of mouse embryonic stem cells (mESCs)-derived cardiomyocytes. 276 genes were upregulated (≥ 4fold) in mESCs-derived cardiomyocytes compared undifferentiated ESCs. Secreted phosphoprotein 2 (Spp2) is one of candidates and is known to inhibit bone morphogenetic protein 2 (BMP2) signal transduction as a pseudoreceptor for BMP2. However, its function in cardiomyogenesis is unknown. We confirmed that Spp2 expression increased during the differentiation into functional cardiomyocytes using mESCs, TC-1/Kh2 and E14. Interestingly, Spp2 secretion transiently increased 3 days after formation of embryoid bodies (EBs), indicating that the extracellular secretion of Spp2 is involved in the differentiation of ESCs into cardiomyocytes. To characterize Spp2, we performed experiments using the C2C12 mouse myoblast cell line, which has the property of shifting the differentiation pathway from myoblastic to osteoblastic by treatment with BMP2. Similar to the differentiation of ESCs, transcription of Spp2 increased as C2C12 myoblasts differentiated into myotubes. In particular, Spp2 secretion increased dramatically in the early stage of differentiation. Furthermore, treatment with Spp2-Flag recombinant protein promoted the differentiation of C2C12 myoblasts into myotubes. Taken together, we suggest a novel bioactive protein Spp2 that differentiates ESCs into cardiomyocytes. This may be useful for understanding the molecular pathways of cardiomyogenesis and for experimental or clinical promotion of stem cell therapy for ischemic heart diseases.