• Journal of Chest Surgery
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• v.38 no.10 s.255
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• pp.661-668
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• 2005

Background: We have hypothesized that, if a low resistant gravity-flow membrane oxygenator is used, then the twin blood sacs of TPLS can be located at downstream of the membrane oxyenator, which may double the pulse rate at a given pump rate and increase the pump output. The purpose of this study was to determine the optimal configuration for the ECLS circuits by using the concept of pulse energy and pump output. Material and Method: Animals were randomly assigned to 2 groups in a total cardiopulmonary bypass model. In the serial group, a conventional membrane oxygenator was located between the twin blood sacs. In the parallel group, the twin blood sacs were placed downstream of the gravity-flow membrane oxygenator. Energy equivalent pressure (EEP) and pump output were collected at pump-setting rates of 30, 40, and 50 BPM. Result: At the given pump-setting rate, the pulse rate was doubled in the parallel group. Percent changes of mean arterial pressure to EEP were $13.0\pm1.7,\; 12.0\pm1.9\;and\;7.6\pm0.9\%$ in the parallel group, and $22.5\pm2.4,\; 23.2\pm1.9,\;and\;21.8\pm1.4\%$ in the serial group at 30, 40, and 50 BPM of pump-setting rates. Pump output was higher in the parallel circuit at 40 and 50 BPM of pump-setting rates $(3.1\pm0.2,\;3.7\pm0.2L/min\;vs.\;2.2\pm0.1\;and\;2.5\pm0.1L/min,\;respectively,\;p=0.01)$. Conclusion: Either parallel or serial circuit configuration of the ECLS generates effective pulsatility. As for the pump out, the parallel circuit configuration provides higher flow than the serial circuit configuration.

• 순환기질환의공학회:학술대회논문집
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• 2006.10a
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• pp.36-37
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• 2006

• Journal of agriculture & life science
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• v.52 no.6
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• pp.127-138
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• 2018

In this study, the operational characteristics of a domestic vegetable transplanter were investigated. The main functional components and power path of the tranplanter were analyzed. The link structure of transplanting device waskinematically analyzed, and 3D modeling and dynamic simulation were performed. Based on this analysis, the trajectory of the bottom end of the transplanting hopper was analyzed. Also, the plant spacing according to the engine speed and the shifting stage of transplanting transmission was analyzed and verified by field test. As main results of this study, the transplanting device is one degree of freedom(DOF) 4-bar link type mechanism which comprises 10 links and 13 rotating joints. The transplanting hopper plants seedlings in a vertical direction while maintaining a constant posture by the links of transplanting device. The power is transmitted to both the driving part and transplanting part from the engine, and the maximum and minimum plant spacing of the transplanting device were 428.97 mm and 261.20 mm.

• Journal of Chest Surgery
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• v.37 no.3
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• pp.201-209
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• 2004

Extracorporeal life support (ECLS) system is a device for respiratory and/or heart failure treatment, and there have been many trials for development and clinical application in the world. Currently, a non-pulsatile blood pump is a standard for ECLS system. Although a pulsatile blood pump is advantageous in physiologic aspects, high pressure generated in the circuits and resultant blood cell trauma remain major concerns which make one reluctant to use a pulsatile blood pump in artificial lung circuits containing a membrane oxygenator. The study was designed to evaluate the hypothesis that placement of a pressure-relieving compliance chamber between a pulsatile pump and a membrane oxygenator might reduce the above mentioned side effects while providing physiologic pulsatile blood flow. The study was performed in a canine model of oleic acid induced acute lung injury (N=16). The animals were divided into three groups according to the type of pump used and the presence of the compliance chamber, In group 1, a non-pulsatile centrifugal pump was used as a control (n=6). In group 2 (n=4), a single-pulsatile pump was used. In group 3 (n=6), a single-pulsatile pump equipped with a compliance chamber was used. The experimental model was a partial bypass between the right atrium and the aorta at a pump flow of 1.8∼2 L/min for 2 hours. The observed parameters were focused on hemodynamic changes, intra-circuit pressure, laboratory studies for blood profile, and the effect on blood cell trauma. In hemodynamics, the pulsatile group II & III generated higher arterial pulse pressure (47$\pm$ 10 and 41 $\pm$ 9 mmHg) than the nonpulsatile group 1 (17 $\pm$ 7 mmHg, p<0.001). The intra-circuit pressure at membrane oxygenator were 222 $\pm$ 8 mmHg in group 1, 739 $\pm$ 35 mmHg in group 2, and 470 $\pm$ 17 mmHg in group 3 (p<0.001). At 2 hour bypass, arterial oxygen partial pressures were significantly higher in the pulsatile group 2 & 3 than in the non-pulsatile group 1 (77 $\pm$ 41 mmHg in group 1, 96 $\pm$ 48 mmHg in group 2, and 97 $\pm$ 25 mmHg in group 3: p<0.05). The levels of plasma free hemoglobin which was an indicator of blood cell trauma were lowest in group 1, highest in group 2, and significantly decreased in group 3 (55.7 $\pm$ 43.3, 162.8 $\pm$ 113.6, 82.5 $\pm$ 25.1 mg%, respectively; p<0.05). Other laboratory findings for blood profile were not different. The above results imply that the pulsatile blood pump is beneficial in oxygenation while deleterious in the aspects to high pressure generation in the circuits and blood cell trauma. However, when a pressure-relieving compliance chamber is applied between the pulsatile pump and a membrane oxygenator, it can significantly reduce the high circuit pressure and result in low blood cell trauma.

• Journal of agriculture & life science
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• v.53 no.4
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• pp.113-124
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• 2019

In this study, the operational characteristics of a cam-type vegetable transplanter which usually used in domestic was analyzed and operating mechanism of a transplanting device was analyzed. The main components and power path of the transplanter were analyzed. The maximum and minimum control cycles according to the moving speed and the plant spacing were analyzed. 3D modeling and simulation were performed to derive the trajectory of the bottom end of the transplanting hopper and the plant spacing at the each operating condition. The simulation results were verified by the field tests. As main findings of this study, the transplanting device has one degree of freedom (DOF) which consist of 13 links, 17 rotating joints and 1 half joint, and each part has composite structure with cam and links. By continuous and repetitive motion of the structures of transplanting device, the transplanting hopper plants the seedling in the ground with a vertical direction, and the seedling was planted stably. The power is transmitted to the driving part and transplanting device from the engine, and the maximum and minimum plant spacing of the transplanting device were about 900 mm and 350 mm, respectively.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.05a
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• pp.23-25
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• 2019

낸드 플래시 메모리(NAND Flash Memory)는 컴퓨터 시스템의 대용량 저장장치를 위한 소자로써, 대용량화의 주요 원인으로는 메모리 셀(Cell) 당 저장할 수 있는 비트 수를 증가시킴으로써 집적도를 증가시킨 것이다. 그러나, 이러한 집적도의 증가는 에러의 증가를 가져와서 저장장치에서 가장 중요한 신뢰성이 급격하게 저하하는 요인이며, 저장장치의 생명주기(Lifetime)을 감소시키게 된다. 기존에 낸드 플래시 메모리 저장장치의 Lifetime을 증대시키기 위해서 P/E cycle을 고려하여 데이터 영역의 일부를 점점 더 ECC 영역으로 변경시키는 방식을 적용한 바가 있다. 이러한 방식은 데이터 영역의 감소로 인한 저장장치 내에서 관리되는 호스트-플래시 간 데이터 관리 크기의 미스매치로 인한 여러 가지 오버 헤드를 생성한다. 본 연구에서는 P/E cycle에 따른 데이터 영역의 ECC 영역으로의 전환을 통한 Lifetime을 증가시키는 방식에 있어서, 오버헤드를 줄이기 위한 캐쉬 관리 구조 및 매핑 관리 구조에 대한 설계를 진행하였다. 이러한 설계를 낸드 플래시 메모리 기반 저장장치에 적용할 경우, LifeTime을 증대시키기 위해서 ECC를 데이터 영역으로 확장하는 방식을 사용할 때 저하될 수 있는 일반 읽기 및 쓰기의 성능 저하를 어느 정도 감소시켜줄 수 있을 것으로 기대한다.

• Journal of Chest Surgery
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• v.40 no.12
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• pp.874-877
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• 2007

Airway management is difficult problem in severe tracheal stenosis. A total airway obstruction during the procedure resulted in a fatal outcome. We suggest a tracheostomy assisted with an emergency bypass system as a possible method for avoiding this complication.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.1660-1664
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• 2008

Extra-corporeal Life Support System (ECLS) is the device used in emergency cases to substitute a extracorporeal circulation in open heart surgery, cardiac arrest or in acute cardiopulmonary failure. To obtain the effect of counter-pulsation on hemodynamic response in the ECLS quantitatively, we developed cardiovascular model which consists of 12 compartment model of heldt et al. and 3 compartment model of Schreiner et al. based on windkessel approximation. We compared coronary perfusion, arterial pulse pressure, cardiac output, and left ventricular pressure-volume diagram according to flow configuration such as counter-pulsation, copulsation, and continous flow. When counter-pulsation was applied, 5% higher coronary perfusion, 26% lower pulse pressure, and 2% higher cardiac output than copulsation condition were calculated. We conclude that counter-pulsation configuration in the ECLS is hemodynamically more stable than copulsation and influences the positive effect to recover ventricles.

• Korean Chemical Engineering Research
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• v.59 no.1
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• pp.100-105
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• 2021

This paper proposes the polydimethylsiloxane (PDMS) blade coating method for fabrication of paper-based analytical device (PAD) that is able to monitor the disease diagnosis and progress without special analytical equipment. The mold that has PAD design is easily modified by using laser cutting technique. And the fabricated mold is used for hydrophobic barrier formation by blade coating. We have optimized the stable formation of PDMS hydrophobic barrier as blade coating condition, which is established by analyzing the structure of the PDMS hydrophobic barrier and change of hydrophilic channel size as thickness of the ink and contact time with the chromatography paper. Based on optimal condition, we demonstrate that PAD as biosensor can apply to detect protein, glucose, and metal ion without special analysis equipment.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.400-400
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• 2022

관로 내 빈번히 발생하는 수격압의 발생은 관망 구조물에 피로가 누적되고 관벽에 손상을 발생시켜, 관로 내 누수가 다양한 형태로 생성된다. 관 내 누수가 발생되는 경우 관 내부의 수격압의 발생 시 생성되는 부압으로 인하여 외부 물질이 관으로 흡수되거나 혼합되어 스케일과 미생물의 생성되는 등 관 내의 수질에 악영향을 끼치며 마찰을 증가시켜 통수능이 감소하고 관리에 추가적인 비용을 발생시킨다. 이러한 영향을 방지하기 위해 관 내에서 생성되는 누수를 탐지하기 위하여 수격압을 발생시켜 압력파를 분석하거나 추적을 수행하는 여러 가지 연구들이 수행되었다. 본 연구에서는 현장 관망과 연결된 100A 대구경 관로에 관로 수압 발생장치를 연결하여 기존의 수격압을 발생시켜 분석하는 방법 대신 안전하고 용이한 방법인 압력파를 주입하여 실험을 수행하였다. 실험을 통해 획득한 데이터를 시간상에서 분석하고 Fourier 변환을 통한 빈도상 분석과 Wavelet 분석으로 신호주기에서 누수가 미치는 영향을 파악하였다. 실험 결과에서는 누수에 의한 영향으로 반사파가 직접적으로 변형되는 형태보다 시스템 전체에서 반영되어 수두가 감쇠되는 형태로 나타났다. Fourier 변환을 통해 무누수 조건과 누수조건의 비교에서 누수의 유무에 따른 신호의 형태가 차이를 보였다. 앞선 연구들에서의 누수의 특정한 위치를 찾아내는 형태 대신 신호처리 후 분석을 통해 시스템 전체에서 일어나는 감쇠를 통해 누수 존재 유무를 판별하고자 한다.